• 융합정보논문지
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• 제11권12호
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• pp.39-48
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• 2021

본 연구의 목적은 COVID-19 상황에서 간호대학생의 그릿, 회복탄력성, 학업적 자기효능감, 소진의 정도를 파악하고 소진에 영향을 미치는 요인을 확인하기 위함이다. 2021년 5월 11일부터 5월 25일까지 G시 소재 대학에 재학 중인 간호대학생 3학년 155명을 대상으로 하였다. 자료분석은 t-test, ANOVA, Scheffe, Kruskal-Wallis test, Pearson's correlation, 다중회귀분석으로 분석하였다. 통계학적으로 소진은 그릿, 회복탄력성, 학업적 자기효능감과 유의한 역 상관관계를 보였다. 소진에 대한 영향요인은 회복탄력성, 전공만족도, 학업적 자기효능감, 임상실습만족도로 총 변화량의 60%를 설명하였다. 본 연구를 바탕으로 COVID-19 상황에서 간호대학생의 소진을 감소시키기 위해 회복탄력성, 전공만족도, 학업적 자기효능감, 임상실습만족도를 높이기 위한 전략이 필요하다.

• Journal of Radiation Protection and Research
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• 제44권2호
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• pp.79-88
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• 2019

Background: The main goal of experiments is to compare various operational and technical characteristics of D-Shuttle semiconductor personal dosimeters of the Japanese company "Chiyoda Technol Corporation" and Harshaw thermoluminescent dosimeters (TLD) manufactured by "Thermo Fisher Scientific" and DTL-02 of the Russian Research and Production Enterprise (RPE) "Doza" by their occupational and calibration exposure at various dose equivalents from 0.5 to 20 mSv of gamma-radiation. Materials and Methods: Besides dosimeters DTL-02, D-Shuttle and Harshaw TLD, there were also used: (1) the primary reference radionuclide source Hopewell Designs IAEA: G10-1-12 with $^{137}Cs$ isotope (an error is not more than 6% and activity is 20 Ci), and (2) the verification device UPGD-2M of RPE "Doza" and installed in the National Center for Expertise and Certification of the Republic of Kazakhstan (Kapchagai, the National Center for Expertise and Certification). Results and Discussion: The main results of researches are the following: (1) TLDs for Harshaw 6600 and DVG-02TM have an approximately equal measurement accuracy of the individual dose equivalents in the range from 0.5 to 20 mSv of gamma-radiation. (2) Advantages of dosimeters for Harshaw 6600 are due to the high measurement productivity and opportunity to indicate the dose on the skin $H_p$(0.07). Advantages of DVG-02TM consist of operation simplicity and lower cost than of Harshaw 6600. (3) D-Shuttles are convenient for use in the current and the operational monitoring of ionizing radiation. Measurement accuracy and 10% linearity of measurements are ensured when D-Shuttle is irradiated with dose equivalents below 1 mSv at the equivalent dose rate not higher than $3mSv{\cdot}hr^{-1}$. This allows using D-Shuttle at a routine technological activity. Conclusion: The obtained results of experiments demonstrate advantages and disadvantages of D-Shuttle semiconductor dosimeters in comparison with two TLD systems of DVG-02TM and Harshaw 6600.

• 자원환경지질
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• 제46권5호
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• pp.375-390
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• 2013

켄티차(Kenticha) 희유원소(Ta-Li-Nb-Be) 광화대는 에티오피아 남부의 오피올라이트 습곡-쓰러스트 복합체내에 위치하고 있으며, 1980년대 에티오피아-구소련간 수행된 공동탐사 프로그램을 통해서 처음 발견되었다. 켄티차 희유원소 광화대는 남쪽에서 북쪽으로 덜미다마(Dermidama), 킬킬리(Kilkele), 슈니힐(Shuni Hill), 켄티차, 부포(Bupo) 페그마타이트를 포함한다. 켄티차 페그마타이트는 남북방향의 사문암과 활석-녹니석 편암층을 평행하게 관입하고 있으며, 대략 연장 2 km, 폭 400-700 m로 노출되어 있다. 켄티차 페그마타이트는 내부적으로 대상(zoning)을 이루고 있으며, 광물조합에 따라 하부 석영-백운모-조장석 화강암, 중부 백운모-석영-조장석-미사장석 페그마타이트, 상부 스포듀민-석영-조장석 페그마타이트로 세분된다. 주성분, 미량성분(Rb, Li, Nb, Ta, Ga), 원소비(K/Rb, Nb/Ta, Mg/Li, Al/Ga)는 페그마타이트의 분별작용과 고화작용이 하부에서 상부 페그마타이트로 진행되었음을 시사한다. 반면에 일반적인 페그마타이트 멜트의 분화양상과 달리 켄티차 페그마타이트의 Mg/Li 비는 상부 페그마타이트로 가면서 증가하는 양상을 보인다. 이러한 양상은 후기 마그마성 열수변질 또는 상부 초염기성암과의 반응 결과로 해석된다. 켄티차 페그마타이트의 희유원소 광화작용은 상부 페그마타이트에 집중되며, 최대 $Li_2O$ 3.0%, Rb 3,780 pm, Cs 111 ppm, Ta 1,320 ppm, and Nb 332 ppm을 함유하고 있다. 켄티차 페그마타이트에서 광석광물은 주로 탄탈라이트, 스포듀민, 레피돌라이트가 산출되며, 탄탈라이트는 거정의 석영-스포듀민과 상대적으로 세립의 당상 조장석과 함께 산출된다. 탄탈라이트는 $Mn^*$과 $Ta^*$ 값에 근거할 때 Mn-탄탈라이트로 분류된다. 거정질과 세립의 탄탈라이트는 조성($Mn^*$, $Ta^*$, Nb/Ta) 차이가 명확히 나타나며, 거정질 탄탈라이트는 세립의 탄탈라이트에 비해 Ta이 강하게 부화되며 Nb은 결핍되어 있다. 결론적으로 켄티차 페그마타이트에서 희유원소 광화작용은 마그마 멜트의 분별작용 최후기에 형성되었다.

• Imaging Science in Dentistry
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• 제30권3호
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• pp.189-198
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• 2000

Purpose: The study was aimed to detect the induction of apoptosis, cell cycle arrest and calcified nodule formation after irradiation on primarily cultured osteoblasts. Materials and Methods: Using rat calvarial osteoblasts, the effects of irradiation on apoptosis, cell cycle arrest, and calcified nodule formation were studied. The single irradiation of 10 and 20 Gy was done with 5.38 Gy/min dose rate using the l37Cs cell irradiator at 4th and 14th day of culture. Apoptosis induction and cell cycle arrest were assayed by the flowcytometry at 1, 2, 3, and 4 days after irradiation. The formation of calcified nodules was observed by alizarin red staining at 1, 3, 10, 14 days after irradiation at 4th day of culture, and at 1, 4, 5 days after irradiation at 14th day of culture. Results: Apoptosis was not induced by 10 or 20 Gy independent of irradiation and culture period. Irradiation did not induced G1 arrest in post-irradiated ostedblasts. After irradiation at 4th-day of culture, G2 arrest was induced but it was not statistically significant after irradiation at 14th-day of culture. In the case of irradiated cells at 4th day of culture, calcified nodules were not formed and at 14th-day of culture after irradiation, calcified nodule formation did not affected. Conclusion: Taken together, these results suggest that irradiation at the dose of 10-20 Gy would not affect apoptosis induction of osteoblasts. Cell cycle and calcified nodule formation were influenced by the level of differentiation of osteblasts.

• 한국결정성장학회지
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• 제3권1호
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• pp.66-74
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• 1993

칼륨-흑연 층간 화합물(K-GIC)을 변형된 Two-buib법에 의하여 흑연의 반응 온도 변화($T_g:450^{\circ}C$ , $400^{\circ}C$, $350^{\circ}C$, $300^{\circ}C$, $250^{\circ}C$) 에 따라 정체된 천연흑연으로부터 합성하였고 합성된 K-GIC는 X-선 회절법을 이용하여 stage 형성과정을 확인하였으며, 이때 1 stage, 2 stage에 있어서 (001)회절선의 d 값은 $5.35\AA$과 $8.73\AA$ 에 해당하였다. K-GIC의 stage 안정성과 에너지 상태는 UV/VIS Spectrophotometer를 사용하여 알 수 있었으며 측정결과T_g$가 $250^{\circ}C$일 때 Reflectance의 최소값이 2.67eV(465nm)의 높은 에너지쪽으로 이동하였으며, 즉 X-선 회절법과 UV/VIS spectrophotometric data로부터 흑연의 탄소원자들 사이에 전하운반자가 많이 존재하여 낮은 stage가 형성되었음을 제시하고 있으며, 또한 이들 결과는 K-GIC의 전자물성과 그 밖의 물리적 성질에 대한 정보를 제공하여 주고 있다. 특히 지금까지 연구 보고된 바에 의하면 이 값들은 연구자에 따라 다르므로 본 연구를 통하여 정확한 값을 측정 제시하게 되었다.

• 한국가금학회지
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• 제38권2호
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• pp.137-144
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• 2011

본 시험은 토종닭의 교배 조합이 계육의 지방산과 아미노산 및 핵산 관련 물질 함량에 미치는 영향을 조사하기 위하여 수행되었다. 공시계는 4개 교배 조합으로 발생된 3원 교잡종을 이용하였다. 시험 설계는 A(CS${\times}$B), B(CH${\times}$S), C(RS${\times}$H), D(백세미)로 하였으며, 4처리구에 따라 암수 각각 9반복, 반복당 10수씩($4{\times}2{\times}9{\times}10$) 총 720수를 완전 임의 배치하였다. 시험 사료는 제시한 옥수수-대두박 위주의 준육용계 사료를 자체 제작하여 이용하였다. 5주령 계육의 포화지방산의 함량은 C처리구에서 가장 낮았으며, A처리구가 가장 높았다(p<0.05). 10주령 계육의 포화지방산의 함량은 5주령 계육과 마찬가지로 C처리구에서 가장 낮았으며, A처리구가 가장 높았다(p<0.05). 계육의 아미노산 함량은 모든 계육의 필수 아미노산 함량은 lysine, leucine, arginine, phenylalanine 등의 순이었고, 비필수 아미노산 함량은 glutamic acid, aspartic acid, alanine 등의 순이었다. 5주령에서는 필수 아미노산 중 valine, leucine, phenylalanine 및 lysine은 A계통에서 가장 낮게 나타났으며, phenylalanine과 lysine 함량은 B계통에서 가장 높았다(p<0.05). 비필수 아미노산 중 cystine, aspartic acid, glycine, alanine 및 proline은 A계통에서 가장 낮았고(p<0.05), 다른 계통들 사이에서는 차이가 없었다. 10주령 계육의 아미노산 함량은 모든 처리구에서 유의적인 차이가 없었다. 계육의 핵산 관련 물질 중 hypoxanthine(Hx)은 5주령에서 C처리구가 14.5%로 가장 높게 나타났으나, 10주령에서는 B처리구가 9.29%로 가장 높게 나타났다(p<0.05). 처리구간 계육의 Inosine monophosphate(IMP)는 각각 131.4 mg/100 g, 187.7 mg/100 g, 250.2 mg/100 g 및 214.0 mg/100 g으로 A, B, C처리구 사이에 유의차가 있었다(p<0.05). 10주령의 IMP는 C처리구가 258.6 mg/100 g으로 가장 높았고(p<0.05), A, B, D처리구 사이에서는 차이가 없었다. 5주령의 adenosine mono phosphate(AMP)는 처리구간 차이가 없었으나, 10주령에서는 5.46 mg/100 g, 5.96 mg/100 g, 5.45 mg/100 g 및 5.47 mg/100 g으로 B처리구에서 가장 높게 나타났다(p<0.05).

• Journal of Microbiology
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• 제33권2호
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• pp.154-159
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• 1995

SH-14, a novel killer strain of Ustilago maydis was isolated in Korea. It has been reported in other papers that the toxin specificity and double-stranded RNA pattern of SH-14 strain were different from other laboratory strains. In this paper, we analyzed the biochemical characteristics of U. maydis SH-14 virus. Three distinctive peaks were isolated from CsCl density gradient, designated as top (T), intermediate (I) and bottom (B) components. We found that the densities of each components, 1.285, 1.408 g/cm$\^$3/, respectively, are very similar to those of other strains. As previously reported by the analysis of dsRNA in each component, the dsRNA segments are separately encapsidated. Capsid protein of SH-14 virus consists of two proteins about 70 Kd shown by SDS-PAGE analysis. Electron microscopic examination of the virus particles revealed that UmV particles are very similar in size and morphology to all isolates as well as all lab-strains. In order to test immunological cross reactivity of UmV, werstern bolt analysis was carriedout with antiserum against A8 virus. All capsid protein had positive reaction against A8 antibody which indicated that UmV are immunologically cross-reactive with all isolates from Korea. The results presented in this paper may show that UmV isolated from SH-14 strain has very similar biochemical characteristics to those of other UmV. However, the difference in the toxin specificity and the molecular weight of toxin protein from the SH-14 strain has us to conclude that U. maydis SH-14 strain is a new killer type.

• 대한미생물학회지
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• 제17권1호
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• pp.87-93
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• 1982

Two cases of pulmonary disease in a 54 year-old female and a 70 year-old male patient due to Mycobacterium avium-intracellulare complex(MAIC) and a case of pulmonary infection ina 69 year-old male patient due to M. fortuitum(MF) were found recently in this institute. All three patients had a long history of anti-tuberculous chemotherapy because they were initially diagnosed as pulmonary tuberculosis. A 70 year-old male patient infected with MAIC had an unsuccessful chemotherapy history of isoniazid(INH), para-aminosalicylic acid(PAS) and streptomycin(SM) with an incomplete, temporary, symptomatic improvement, for three years since 1964 when he was first diagnosed as pulmonary tuberculosis on physical examination. A 54 year-old female patient infected with MAIC also had an unsuccessful chemotherapy history with the various anti-tuberculous drugs since 1958. Both patients discharged large number of MAIC in their sputum specimens for at least more than one year, but no M. tuberculosis at all. A 69 year-old male patient infected with MF was diagnosed as moderately advanced pulmonary tuberculsis in 1977. Combined chemotherapy with INH+PAS+pyrazinamide(PZA) improved his clinical symptoms, however, his chest radiograph was deteriorated again in 1980 one year after he stopped therapy. Therefore he started chemotherapy again with INH+ethionamide(TH)+cycloserine(CS) but no improvement was noticed. MF was cultured from his sputum in August 1981 and he continuously discharged the same bacilli until last examination of January 1982. Whether all three patients were initially !infected with nontuberculous mycobacteria or complicated with predisposing tuberculosis was not clear because there were no reliable bacteriological examination records.

• Asian-Australasian Journal of Animal Sciences
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• 제16권6호
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• pp.806-812
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• 2003

Attempts have been made to establish relationship between the response to ACTH challenge in female calves, growth and first lactation performance. A total of 19 Holstein calves weighing 100 kg i. v. were given 0.50 IU of ACTH/kg $BW^{.75}$ (EXACTHIN inj., Richter G., Budapest) at 60 days of age. Serial blood samples were taken at times 0, 0.5, 1, 2, 3, 4 and 5 hours and analyzed for cortisol, glucose insulin and FFA levels. From challenge series the area under the curve from time of administration and the following 5 h were calculated. Negative, and mostly loose relationship between response to ACTH challenge for cortisol, insulin, or FFA and ADWG during growth have been established (p>0.05) with positive one for glucose. Bivariate coefficients of correlation varied within the range from -0.35 to 0.15. Estimations reveal negative correlation between the length of first lactation and cortisol or insulin (r=-0.80, p<0.001 and r=-0.45, p<0.10, resp.) Close association between cortisol or insulin and actual first lactation milk yield was found (r=-0.48, p<0.10; r=-0.64, p<0.01, resp.). Close relationship between the response to ACTH challenge and milk protein yield was present only for insulin (r=-0.59, p<0.05).

• 한국의학물리학회지:의학물리
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• 제30권4호
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• pp.89-93
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• 2019

Purpose: This study aims to develop new markers based on silicone rubber and urethane rubber to enhance visibility in low magnetic field magnetic resonance (MR) imaging. Methods: Four types of markers were fabricated using two different base materials. Two of the markers were composed of two different types of silicone rubber: DragonSkin™ 10 MEDIUM and BodyDouble™ SILK. The other two markers were composed of types of urethane rubber: PMC™ 780 DRY and VytaFlex™ 20. Silicone oil (KF-96 1000cs) was added to the fabricated markers. The allocated amount of oil was 20% of the weight (wt%) of each respective marker. The MR images of the markers, with and without the silicone oil, were acquired using MRIdian with a low magnetic field of 0.35 T. The signal intensities of each MR image for the markers were analyzed using ImageJ software and the visibility for each was compared. Results: The highest signal intensity was observed in VytaFlex™ 20 (279.67±3.57). Large differences in the signal intensities (e.g., 627% in relative difference between BodyDouble™ SILK and VytaFlex™ 20) among the markers were observed. However, the maximum difference between the signal intensities of the markers with the silicone oil showed only a 62% relative difference between PMC™ 780 DRY and DragonSkin™ 10 MEDIUM. An increase in the signal intensity of the markers with the silicone oil was observed in all markers. Conclusions: New markers were successfully fabricated. Among the markers, DragonSkin™ 10 MEDIUM with silicone oil showed the highest MR signal intensity.