• 제목/요약/키워드: 3DPC

검색결과 75건 처리시간 0.028초

통계모형을 활용한 박새류의 서식지 연결성 평가: 서울시 도시생태현황도 자료를 중심으로 (Habitat Connectivity Assessment of Tits Using a Statistical Modeling: Focused on Biotop Map of Seoul, South Korea)

  • 송원경;김은영;이동근
    • 환경영향평가
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    • 제22권3호
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    • pp.219-230
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    • 2013
  • Species distribution modeling is one of the most effective habitat analysis methods for wildlife conservation. This study was for evaluating the suitability of species distribution to distance between forest patches in Seoul city using tits. We analyzed the distribution of the four species of tits: varied tit (Parus varius), marsh tit (P. palustris), great tit (P. major) and coal tit (P. ater), using the landscape indexes and connectivity indexes, and compared the resulting suitability indexes from 100m to 1,000m. As factors affecting to the distribution of tits, we calculated landscape indices by separating them into intra-patch indices (i.e. logged patch area (PA), area-weighted mean patch shape index (PSI), tree rate (TR)) and inter-patch indices (i.e. patch degree (PD), patch betweenness (PB), difference probability of connectivity (DPC)), to analyze the internal properties of the patches and their connectivity by tits occurrence data using logistic regression modeling. The models were evaluated by AICc (Akaike Information Criteria with a correction for finite sample sizes) and AUC (Area Under Curve of ROC). The results of AICc and AUC showed DPC, PA, PSI, and TR were important factors of the habitat models for great tit and marsh tit at the level of distance 500~800m. In contrast, habitat models for coal tit and varied tit, which are known as forest interior species, reflected PA, PSI, and TR as intra-patch indices rather than connectivity. These mean that coal tit and varied tit are more likely to find a large circular forest patch than a small and long-shaped forest patch, which are higher rate of forest. Therefore, different strategies are required in order to enhance the habitats of the forest birds, tits, in a region that has fragmented forest patches such as Seoul city. It is important to manage forest interior areas for coal tit and varied tit, which are known as forest interior species and to manage not only forest interior areas but also connectivity of the forest patches in the threshold distance for great tit and marsh tit as adapted species to the urban ecosystem for sustainable ecosystem management.

Structure-Activity Relationships of Peptide Antibiotics with Improved Bacterial Cell Selectivity of Pseudin

  • Lee, Yeongjoon;Jeon, Dasom;Kim, Jin-Kyoung;Kim, Yangmee
    • 한국자기공명학회논문지
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    • 제21권3호
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    • pp.78-84
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    • 2017
  • Pseudin is a naturally occurring 24 amino-acid-residue antimicrobial peptide derived from the skin of paradoxical frog Pseud's paradoxa. It shows potency against the bacteria and antibiotic-resistant bacteria strain, but has high cytotoxicity against mammalian cell. In our previous study, substitution of $Pro^{11}$ for Gly (Ps-P) increased bacterial cell selectivity but decreased the antibacterial activity of pseudin. In this study, we designed pseudin analogue, Ps-4K-P with increased cationicity up to +7 in Ps-P by substituting Glu14, Gln10, Gln24, and Leu18 with Lys. Ps-4K-P showed improved potent antibacterial activity with high bacterial cell selectivity. We determined the tertiary structure of Ps-4K-P in the presence of DPC micelles by NMR spectroscopy and it has a hinge structure at $Pro^{11}$ followed by three turn helices from $Pro^{11}$ to $Val^{23}$ at the C-terminus. Amphipathicity with increased cationicity as well as helix-hinge-helix structural motif provided by introduction of a Pro at position $Gly^{11}$ are the crucial factors which confer antibacterial activity with bacterial cell selectivity to Ps-4K-P.

A Novel Control Scheme for T-Type Three-Level SSG Converters Using Adaptive PR Controller with a Variable Frequency Resonant PLL

  • Lin, Zhenjun;Huang, Shenghua;Wan, Shanming
    • Journal of Power Electronics
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    • 제16권3호
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    • pp.1176-1189
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    • 2016
  • In this paper, a novel quasi-direct power control (Q-DPC) scheme based on a resonant frequency adaptive proportional-resonant (PR) current controller with a variable frequency resonant phase locked loop (RPLL) is proposed, which can achieve a fast power response with a unity power factor. It can also adapt to variations of the generator frequency in T-type Three-level shaft synchronous generator (SSG) converters. The PR controller under the static α-β frame is designed to track ac signals and to avert the strong cross coupling under the rotating d-q frame. The fundamental frequency can be precisely acquired by a RPLL from the generator terminal voltage which is distorted by harmonics. Thus, the resonant frequency of the PR controller can be confirmed exactly with optimized performance. Based on an instantaneous power balance, the load power feed-forward is added to the power command to improve the anti-disturbance performance of the dc-link. Simulations based on MATLAB/Simulink and experimental results obtained from a 75kW prototype validate the correctness and effectiveness of the proposed control scheme.

시금치(Spinacia oleracea L.) 엽록체의 광합성 전자전달 활성에 미치는 iso-Butanol의 영향 (Effects of iso-Butanol on Photosynthetic Electron Transport Activity in Isolated Spinach Chloroplasts)

  • 박강은
    • Journal of Plant Biology
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    • 제35권3호
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    • pp.247-252
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    • 1992
  • iso-Butanol이 엽록체의 광합성 전자전달 활성에 미치는 영향을 연구하기 위하여 암조건하에서 시금치의 엽록체에 iso-butanol을 처리한 후 대조구와 비교하여 광계 II 활성과 광계 I 활성을 조사하였으며, 또한 iso-butanol이 틸라코이드 막단백질에 미치는 영향을 알아보기 위해 전기영동으로 틸라코이드 막단백질의 변화를 조사하였다. 광계 I 활성은 iso-butanol이 저농도(1-4%)일 때는 증가하였으나 고농도(5-9%) 에서는 감소되었다. 광계 II 활성은 iso-butanol의 농도가 0.6, 0.8, 1%에서는 각각 75%, 55% 및 25%로 활성이 감소하였다. Butanol 중에서 탄소수는 같으나 OH 기의 위치가 다른 1-butanol, sec-butanol, tert-butanol, iso-butanol이 광계 II의 전자전달계에 미치는 영향을 비교해 본 결과 OH 기를 중심으로 탄소의 배열이 직선상 일 때 저해효과가 크다는 것을 알 수 있었다. iso-butanol이 1차적으로 광계 II에 미치는 억제 부위는 0.8% iso-butanol 처리구에 DPC 첨가했을 때 DCIP 환원율이 93%로 증가하는 것으로 보아 광계 II의 산화 부위임을 알 수 있다. 0.8% iso-butanol 처리구에 외부에서 망간과 칼슘을 첨가하였을 때 광계 II 활성이 각각 83%와 79%로 보호된 것으로 보아 광계 II 활성 억제는 망간의 소실과 관계 있는 것으로 생각된다. 또한 1% iso-butanol 처리한 엽록체를 20배 희석하였을 때 활성이 78%로 회복되었다. iso-Butanol은 1% 이하의 저농도에서 광계 II 활성을 감소시킨데 비해 1% iso-butanol 처리구의 틸라코이드 막단백질의 SDS-PAGE에 의한 band pattern은 대조구와 유사하며 2% 처리구에서는 52 Kd 부근에서 미세한 band pattern의 차이가 있으며 5%의 iso-butanol 처리구의 틸라코이드 막단백질의 band는 전체적으로 많이 소실되었다. 이것으로 보아 iso-butanol은 가역적으로 광계 II의 산화부위에 관여하는 단백질에 영향을 주어 $Ca^{2+}와\;Mn^{2+}$ 이온의 친화력을 저하시켜 광계 II 활성을 억제시키고 또한 알코올의 R-group의 틸라코이드 막에 침투하여 막구조를 변형시키므로 광계 I 활성이 증가하며 고농도(5-9%)에서는 비가역적으로 막구조를 변경하여 광계 I 활성이 감소한 것으로 사료된다.

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超音波를 利用한 Dodecyl Pyridinium Chloride 水溶液中의 미셀과 반대이온 사이의 解離-再結合反應의 反應速度論的 硏究 (Kinetic Study using Ultrasonic Technique on the Dissociation-Recombination Reaction between Micelle and Counter-ion in Dodecyl Pyridinium Chloride Solution)

  • 이근무
    • 대한화학회지
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    • 제20권3호
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    • pp.193-197
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    • 1976
  • 界面活性劑 dodecyl pyridinium chloride 水溶液에서의 超音波吸收를 $20^{\circ}C$, 振動數 0.1${\sim}$90 Mc에서 測定하였다. 超過吸收는 cmc 以上의 濃度에서만 觀測되었다. 超音波超過吸收의 메카니즘은 $M_2\;{\rightleftharpoons}\;M_1\;+\;1.2Cl^-$ 反應에 基因됨을 알았다. 여기서 $M_2,\;M_1$은 다른型의 미셀이다. 정, 逆反應速度常數는 각각 $6.6{\times}10^5 sec^{-1},\;2.7{\times}10^11sec^{-1}mol^{-1.2}$임이 觀測되었다. 自由에너지, 엔탈피, 엔트로피등 몇가지 反應速度論的性質도 算出하였다.

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Structure-Activity Relationships of 9-mer Antimicrobial Peptide analogue of Protaetiamycine, 9Pbw2

  • Kim, Jin-Kyoung;Lee, Eun-Jung;Jung, Ki-Woong;Kim, Yang-Mee
    • 한국자기공명학회논문지
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    • 제15권1호
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    • pp.1-13
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    • 2011
  • 9Pbw2 is a 9-mer analog of protaetiamycine derived from the larvae of the beetle Protaetia brevitarsis. Previously, we designed four 9-mer peptide analogues to optimize the balance between the hydrophobicity and cationicity of the peptides and to increase bacterial cell selectivity. Among them, 9Pbw2 has high antibacterial activity without cytotoxicity. The results obtained in previous study suggest that the bactericidal action of 9Pbw2 may be attributed to the inhibition of the functions of intracellular components after penetration of the bacterial cell membrane. In order to understand structure-activity relationships, we determined the three-dimensional structure of 9Pbw2 in 200 mM DPC micelle by NMR spectroscopy. 9Pbw2 has one hydrophobic turn helix from $Trp^3$ to $Arg^8$ and positively charged residues at the N- and C-terminus. This result suggested that positively charged residues from position at the C-terminus in 9Pbw2 may be important for the primary binding to the negatively charged phospholipid head groups in bacterial cell membranes and hydrophobic residues in the middle portion face toward the acyl chains of the hydrophobic lipid in the bacterial cell membrane.

Detergent Screening for NMR-Based Structural Study of the Integral Membrane Protein, Emopamil Binding Protein (Human Sterol Δ8-Δ7 Isomerase)

  • Won, Hyung-Sik
    • 한국자기공명학회논문지
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    • 제21권1호
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    • pp.13-19
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    • 2017
  • Human sterol ${\Delta}8-{\Delta}7$ isomerase, commonly known as emopamil binding protein (EBP), is an essential protein in the cholesterol-synthetic pathway, and mutations of this protein are critically associated with human diseases such as Conradi-Hunermann-Happle or male EBP disorder with neurological defects syndrome. Due to such a clinical importance, EBP has been intensively investigated and some important features have been reported. EBP is a tetra-spanning membrane protein, of which $2^{nd}$, $3^{rd}$, and $4^{th}$ membrane-spanning ${\alpha}$ helices play an important role in its enzymatic function. However, detailed structural feature at atomic resolution has not yet been elucidated, due to characteristic difficulties in dealing with membrane protein. Here, we over-expressed EBP using Escherichia coli and performed detergent screening to find suitable membrane mimetics for structural studies of the protein by NMR. As results, DPC and LMPG could be evaluated as the most favorable detergents to acquire promising NMR spectra for structural study of EBP.

한국 주소의 배달점 코드(DPC:Delivery Point Code) 설계 방안에 관한 연구 (A Study on the Design of Korean Address Delivery Point Code)

  • 왕승진;김호연;이상호;남윤석
    • 한국정보처리학회:학술대회논문집
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    • 한국정보처리학회 2002년도 추계학술발표논문집 (하)
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    • pp.2341-2344
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    • 2002
  • 우편물량 처리에서 병목현상의 원인이 되고있는 수작업에 의한 순로구분 작업을 원활하고 신속하게 처리하며 집배원의 업무 부담을 경감시키기 위해 자동화가 시도되고 있다. 이러한 자동화된 순로구분기의 개발에 있어 순로구분에 필요한 주소 데이터 베이스를 관리하기 위해서는 각 배달지점에 대한 고유한 ID 부여가 필요하다. 따라서 본 논문에서는 아직 체계화되지 않은 한국 주소의 배달점 코드 설계 방안에 대해서 연구하였다. 먼저 해외 각국의 배달점 코드할당 방법을 알아보고, 배달점 코드의 기본 정의 및 설계 방향을 제시한다. 그리고 각 주소의 고유한 배달점 코드를 설계하는데 있어 여러 가지 방안을 제시하고 각 대안별 장단점 및 설계 방법을 제시하였으며 적합한 설계 방안을 선정하였다. 또한 기존의 주소체계뿐만 아니라 도입 예정인 새주소 체계와의 적합성도 고려하였다. 본 논문에서 제시한 우편번호 앞 3자리와 6자리의 일련번호를 연결한 배달점 코드가 현재의 한국 주소체계 뿐만 아니라 새주소 체계에도 적합할 것으로 판단된다. 마지막으로 몇 가지 적용 사례를 통한 제안한 방안들을 검증해 보았다.

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Expression of Heterotic Genetic Interaction among Multivoltine Recurrent Backcross/Congenic Lines for Higher Shell Weight of Silkworm, Bombyx mori L.

  • Verma, A.K.;Chattopadhyay, G.K.;Sengupta, M.;Sengupta, A.K.;Das, S.K.;Urs, S.Raje
    • International Journal of Industrial Entomology and Biomaterials
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    • 제7권1호
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    • pp.21-27
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    • 2003
  • Manifestation of heterotic genetic interaction was studied in different hybrids made between multivoltine recurrent backcross (RBL)/congenic lines (Con. L) during unfavourable season when temperature and relative humidity are > $30^{\circ}C$ and 86%, respectively. A few number of silkworm race or strain or breed like Nistari (N + p or Np) can sustain the temperature above 3$0^{\circ}C$ and RH above 86%. The present heterosis study screened a hybrid i.e., CB$_{5}$Lm5RBL1M$_{6}$DPC-LmE$^1$RBL and its reciprocal provided heterobeltiotic effect on survival by number and pupation rate at a magnitude of 20% (p < 0.01) and yield by weight of 10% (p < 0.01). Beside all the hybrids expressed heterosis over check - Nistari (N + p) with better quality silk. Therefore, aforesaid hybrid may be useful for utilization at commercial level during adverse seasons of West Bengal.gal.

유묘 뿌리썩음병 진전에 따른 이산재배 토양의 유별 (Grouping the Ginseng Field Soil Based on the Development of Root Rot of Ginseng Seedlings)

  • 박규진;박은우;정후섭
    • 한국식물병리학회지
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    • 제13권1호
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    • pp.37-45
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    • 1997
  • Disease incidence (DI), pre-emergence damping-off (PDO), days until the first symptom appeared (DUS), disease progress curve (DPC), and area under disease progress curve (AUDPC) were investigated in vivo after sowing ginseng seeds in each of 37 ginseng-cultivated soils which were sampled from 4 regions in Korea. Non linear fitting parameters, A, B, K and M, were estimated from the Richards' function, one of the disease progress models, by using the DI at each day from the bioassay. Inter- and intra-relationships between disease variables and stand-missing rate (SMR) in fields were investigated by using the simple correlation analysis. Disease variables of the root rot were divided into two groups: variables related to disease incidence, e.g., DI, AUDPC and A parameter, and variables related to disease progress, e.g., B, K and M parameters. DI, AUDPC, and DUS had significant correlations with SMR in ginseng fields, and then it showed that the disease development in vivo corresponded with that in fields. Soil samples could be separated into 3 and 4 groups, respectively, on the basis of the principal component 1 (PC1) and the principal component 2 (PC2), which were derived from the principal component analysis (PCA) of Richards' parameters, A, B, K and M. PC1 accounted for B, K and M parameters, and PC2 accounted for A parameter.

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