• Title/Summary/Keyword: 3D-SG

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Evaluation of Health-related Quality of Life for Hypothesized Medical States Associated with Cervical Cancer

  • Murasawa, Hideki;Konno, Ryo;Okubo, Ichiro;Arakawa, Ichiro
    • Asian Pacific Journal of Cancer Prevention
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    • v.15 no.22
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    • pp.9679-9685
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    • 2014
  • Background: When evaluating health-economics for cervical cancer prevention policies in Japan, it is important to use Japanese value settings. This study aimed to obtain preference-based measures (preference measures) for hypothesized health states among healthy Japanese women, and to examine differences between the EuroQol-5D (EQ-5D) and standard gamble (SG) instruments. Materials and Methods: The investigation was performed among female students at a nursing university. We used written hypothetical scenarios describing three grades of cervical intraepithelial neoplasia (CIN) and eight stages of cervical cancer, both at diagnosis and after medical intervention. Preference measures were evaluated using both EQ-5D and SG. Results: We received responses from 136 women. The mean number of respondents per stage was 24.6 (SD: 2.7). At diagnosis, average EQ-5D scores for CIN1, CIN2, CIN3, IA1, IA2, IB1, IB2, IIA, IIB, III, and IV stages were 0.84 (0.14), 0.78 (0.12), 0.73 (0.10), 0.78 (0.12), 0.72 (0.12), 0.63 (0.13), 0.64 (0.12), 0.68 (0.08), 0.62 (0.13), 0.55 (0.21), and 0.18 (0.24), respectively. Using one-way analysis of variance with the Tukey-Kramer method for multiple comparisons (each stage vs. CIN1), we found significant differences for IB1 and more advanced stages (p<0.05). After medical intervention, corresponding EQ-5D scores were 0.84 (0.12), 0.81 (0.12), 0.84 (0.12), 0.80 (0.15), 0.78 (0.11), 0.64 (0.15), 0.63 (0.15), 0.71 (0.15), 0.50 (0.17), 0.52 (0.17), 0.21 (0.28). The multiple comparisons identified significant differences for IB1 and more advanced stages, excepting IIA (p<0.05). SG evaluations were more variable and relatively higher than EQ-5D evaluations. Conclusions: We obtained preference measures for three grades of CIN1-3 and eight stages of cervical cancer. In combination with appropriate sensitivity analyses, these preference measures will provide a basis for an economic evaluation of cervical cancer prevention in Japan. We suggest that EQ-5D is appropriate for cost-utility analysis of this topic.

Effect of Steviol β-Glucopyranosyl Ester on The Production of Nitric Oxide and Inflammatory Cytokines in RAW 264.7 Cells (Steviol β-Glucopyranosyl Ester가 RAW 264.7 세포의 산화질소 및 염증성 사이토카인 생성에 미치는 영향)

  • Jung, Heehoon;Cho, Uk Min;Hwang, Hyung Seo;Cho, Kun;Lee, Sang Rin;Kim, Moo Sung
    • Journal of the Society of Cosmetic Scientists of Korea
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    • v.44 no.3
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    • pp.239-247
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    • 2018
  • Chronic inflammation is known to have effects on various diseases such as gout, cancer, dementia, atopic disease, and obesity. In addition, since some signal cascades involved in the development of inflammation are known to affect the damage and aging of the skin tissue, studies are being conducted actively to control the inflammation mechanism. In order to mitigate or prevent inflammatory response, a number of researches have been made to develop anti-inflammatory materials from some plants. In particular, Stevia rebaudiana produces steviol glycosides (SG), a natural sweetener with a distinctive flavor. Studies on some of SG have been shown to have anti-inflammatory activity. Researchers of this study expected that more SG also possess anti-inflammatory activity, besides stevioside, rebaudioside A, and steviol. In order to confirm this possibility, the researchers screened inhibition activity of various steviol glucosides for NO production in RAW 264.7 cell lines. As a result, steviol ${\beta}-glucopyranosyl$ ester (SGE) showed the highest inhibitory activity among steviol derivatives treated at the same molar concentration. In addition, we found that mRNA expression level of $interleukin-1{\alpha}$ ($IL-1{\alpha}$), $interleukin-1{\beta}$ ($IL-1{\beta}$), cyclooxygenase-2 (COX-2), nuclear factor kappa-light chain-enhancer of activated B cells ($NF-{\kappa}B$) and inducible nitric oxide synthase (iNOS) was also decreased in a dose-dependent manner. These results show that SGE inhibits anti-inflammatory activity and NO production in mouse macrophage RAW 264.7 cells. It was confirmed that SGE has potential to be applied as an anti-inflammatory material.

Analysis of MRPC Probe Signal According to Defect Size Variation for S/G Tube in Nuclear Power Plant (원전SG세관의 결함크기에 따른 MRPC 프로브의 신호 해석)

  • Kim, Ji-Ho;Song, Ho-Jun;Lim, Keon-Gyu;Lee, Hyang-beom
    • Proceedings of the KIEE Conference
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    • 2005.07b
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    • pp.1008-1010
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    • 2005
  • In the examination of steam generator(SG) tube in nuclear power plant, eddy current testing probes play an important role in detecting the defects. Bobbin probe and MRPC probe is usually used for the inspection of SG tube. Bobbin probe is good at high speed inspection, but ability of detection of circumferential defect is very weak. On the contrary MRPC probe, which moves for inspection in the direction of axial and circumferential simultaneously, has very slow inspection speed, but it has excellent detection capability for small cracks, which is hardly detected by bobbin probe. In this paper, for the accurate analysis of experimental ECT signals, construction of MRPC probe signals database according to the variation of defect size is the main purpose. Using 3-D finite element method, ECT signals are analyzed, and signals analysis add according to frequency ingredient. The results, which are analysis and characteristics ion of electromagnetism simulation signals, is databased.

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Effects of Different Type of Exercise on Blood Variables and Leptin Hormones in SD Rats (훈련방법의 차이가 흰쥐의 혈액성분과 랩틴농도에 미치는 영향)

  • Jin, Young-Wan
    • Journal of Life Science
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    • v.16 no.6
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    • pp.960-963
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    • 2006
  • The purpose of this study is to evaluate the different type of exercise training on the changes of blood variables and leptin in SD rats. For this study, SD rats were divided into three groups: control group (CG: n=10), swim trained group (SG: n=10), and treadmill trained group (TG: n=10). The animals were housed in a pathogen-free animal facility ($22-24^{\circ}C$, 50-60% relative humidity, 08:00-20:00 lighting hours) at D university animal center, Pusan, Korea). Food and water were available ad libitum. The trained rats underwent a 8-wk endurance swim training (5 times/wk) in water at $26-29^{\circ}C$ (SG) and treadmill training (5 times/wk) in DAEJONG treadmill for 60 min. All data were expressed as mean and standard deviation by using SPSS package program (ver 10.0). The result through the statistical analysis of this data were summarized as follows: 1. In the weight changes, there were significant differences among CG, SG and TG(p<.05) after regular swim and treadmill training. TG showed the lowest weight than the other groups. 2. In the epididymal & perirenal adipose tissue levels, there were significant differences among CG, SG and TG(p<.05) after regular swim and treadmill training. TG showed the lowest adipose tissue levels than the other groups. 3. In the triglyceride changes, For the SG and TG, there were significantly decreased after regular swim and treadmill training. TG showed the lowest triglyceride levels than the other groups. 4. In the insulin hormone, For the SG and TG, there were significantly decreased after regular swim and treadmill training. TG showed the lowest insulin levels than the other groups. 5. In the leptin changes, For the SG and TG, there were significantly decreased after regular swim and treadmill training. TG was the lowest than the other groups. Based on the results, Regular swim and treadmill training decrease body weight, epididymal & perirenal adipose tissue levels significantly, this is caused but by decreased triglycerides, insulin, and leptin hormone levels not by the other factors. Regular treadmill training decreased insulin hormone levels compare to swim training, however there was no direct insulin effect on the weight changes. and it might be the direct effect of leptin hormones.

Step-Size Control for Width Adaptation in Radial Basis Function Networks for Nonlinear Channel Equalization

  • Kim, Nam-Yong
    • Journal of Communications and Networks
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    • v.12 no.6
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    • pp.600-604
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    • 2010
  • A method of width adaptation in the radial basis function network (RBFN) using stochastic gradient (SG) algorithm is introduced. Using Taylor's expansion of error signal and differentiating the error with respect to the step-size, the optimal time-varying step-size of the width in RBFN is derived. The proposed approach to adjusting widths in RBFN achieves superior learning speed and the steady-state mean square error (MSE) performance in nonlinear channel environment. The proposed method has shown enhanced steady-state MSE performance by more than 3 dB in both nonlinear channel environments. The results confirm that controlling over step-size of the width in RBFN by the proposed algorithm can be an effective approach to enhancement of convergence speed and the steady-state value of MSE.

MIMO MB-OFDM System (MIMO MB-OFDM 시스템)

  • Heo Joo;Chang Kyung Hi
    • The Journal of Korean Institute of Communications and Information Sciences
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    • v.29 no.10A
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    • pp.1177-1188
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    • 2004
  • This paper describes and analyzes the performance of MB-OFDM UWB system that is suggested as one of standards in IEEE 802.15 TG3a for UWB application. UMBchannel model that has been contributed in IEEE 802.15 SG3a is a wideband channel model of 6Ghz bandwidth, so we modify it to have 3 subband channels that are obtained by filtering conventional U Channel, considering center frequency hopping and system bandwidth. From simulations, we compare performances of MB-OFDM system in AWGN and WB channel and verify the frequency and time domain diversity gains from time End frequency spreading technique. We also compare and analyze the performance of proposed SFBC MB-OFDM with that of conventional MB-OFDM system. Simulation results show SFBC MB-OFDM system outperforms conventional MB-OFDM system about 1.5dB of Eb/No at target BER of 10$^{-m4}$./.

Four New Acetylated Ginsenosides from Processed Ginseng(Sun Ginseng)

  • Park, Il-Ho;Han, Sang-Beom;Kim, Jong-Moon;Piao, Longzhu;Kwon, Sung-Won;Kim, Na-Young;Kang, Tak-Lim;Park, Man-Ki;Park, Jeong-Hill
    • Archives of Pharmacal Research
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    • v.25 no.6
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    • pp.837-841
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    • 2002
  • Four new acetylated ginsenosides were isolated from the processed ginseng (SG, sun ginseng). Their structures were determined to be $3{\beta},{\;}12{\beta}-dihydroxydammar-20(22),24-diene-3-O-{\beta}-D-glucopyranosyl(1{\rightarrow}2)-{\beta}-D-6"-O-acetylglucopyranoside;{\;}3{\beta},12{\beta}-dihydroxydammar-20(21),{\;}24-diene-3-O-{\beta}-D-glucopyranosyl(1{\rightarrow}2)-{\beta}-D-6"-O-acetylglucopyranoside;{\;}3{\beta},{\;}6{\alpha},12{\beta}-trihydroxydammar-20(22),24-diene-6-O-{\beta}-D-6'-O-acetylglucopyranoside{\;}and{\;}3{\beta},6{\alpha},12{\beta}-trihydroxydammar-20(21),24-diene-6-O-{\beta}-D-6'-O-acetylglucopyranoside$ based on spectroscopic evidences. The compounds were named ginsenoside $Rs_4,{\;}Rs_5,{\;}RS_6{\;}and{\;}Rs_7$, respectively.pectively.

The Analysis of Kinematic Difference in Glide and Delivery Phase for the High School Male Shot Putter's Records classified by Year (남자 고등부 포환던지기 선수들의 연도 별 기록에 따른 글라이드와 딜리버리 국면의 운동학적 차이)

  • Park, Jae-Myoung;Chang, Jae-Kwan;Kim, Tae-Sam
    • Korean Journal of Applied Biomechanics
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    • v.23 no.4
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    • pp.295-306
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    • 2013
  • The purpose of this study was to provide high school male shot putters training methods of gliding and delivery motion through comparative analysis of kinematic characteristics. To accomplish this purpose, three dimensional motion analysis was performed for the subjects(PKC, KKH, YDL) who participated in high school male shot putter competition on 92nd (2011), 93rd (2013) National Sports Festival. The subjects were filmed by four Sony HXR-MC2000 video cameras with 60 fields/s. The three-dimensional kinematic data of the glide, conversion and delivery phase were obtained by Kwon3d 3.1 version. The data of the shoulder rotational angles and projection angles were calculated with Matlab R2009a. The following conclusions had been made. With the analysis of the gliding and stance length ratio, the gliding length was shorter at the TG than the SG with short-long technique but the gliding and stance length ratio was 46.8:53.2% respectively. The deviation of the shots trajectory from APSS(Athlete-plus-shot-system) revealed that the PKC showed similar to "n-a-b-c-I" of skilled S-shape type, KKH and YDL showed "n-a-d-f-I'" of unskilled type. Furthermore, they showed smaller radial distance from the central axis of the APSS and the shots were away from the linear trajectory. From this characteristics, The PKC who performed more TG than SG had shorter glide with S-shape of APSS(skilled type) showed the better record than others with technical skill. But KKH and YDL had bigger glide ratio with "n-a-d-f-I'" of unskilled type and improved their records with technical factor. The projection factor had an effect on the record directly. Because PKC maintained more lower glide and transition posture with momentum transfer through COG's rapid horizontal velocity respectively the subject possessed the characteristics of high horizontal and vertical velocity with large turning radius from shot putter to APSS.

Quantitative Estimaton of Amount of Sediment Loss around Round Revetment for Various Inflow Velocities (접근유속에 따른 호안 주변 매립토 유실량의 정량적 평가 방안)

  • Kim, Dong Hyun;Cho, Jae Nam;Kim, Gyu-Seon;Lee, Seung Oh
    • Proceedings of the Korea Water Resources Association Conference
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    • 2016.05a
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    • pp.106-106
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    • 2016
  • 매립공사시 매립토의 유실로 인한 공사기간의 지연, 공사비 증액 등이 발생할 수 있다. 이에 대한 정량적인 예측은 매우 중요하나, 그에 대한 연구는 상대적으로 미비하다. 본 연구에서는 매립토의 유실은 유입된 유사와 호안 표면의 유사가 흐름에 의해 공사구간을 빠져나간 양이라 정하였다. 매립공사에서 유실량의 산정은 매립물량 산정과 직결되며 이는 경제성 부분에서 매우 중요하다. 그러나 국내에서는 경험에 의존한 유실율을 기준으로 매립물량을 결정하고 있는 실정이고, 현장계측으로도 유실량을 정량적으로 판단하기 쉽지않다. 따라서 본 연구에서는 호안 주변의 흐름 특성을 고려한 매립토의 유실량을 정량적으로 평가하기 위한 방안으로 실험적 연구를 수행하였다. 수리실험은 길이 13.0 m, 폭 5.0 m의 직사각형 단면의 광폭 수로에서 수행하였으며 일정한 양의 유사를 유입하기 위해 자체 제작한 유사공급장치를 사용하였다. 매립토의 특성을 고려하기 위하여 일반모래($d_{50}=0.621mm$, SG=2.72)와 안트라사이트($d_{50}=1.547mm$, SG=1.61) 두 가지 유사를 사용하였고, 매립토 유실요인 중 흐름특성에 의해 외부로 유실되는 양을 보다 명확히 규명하기 위해 유사를 유입하기 전과 후의 양을 각각 직접 채취하는 원시적인 방법과 3D 스캔을 통한 방법을 이용하여 평가한 유실율과 비교 검토해 보았다. 두 가지 방법에 대한 상대오차는 최대 3.12%로 나타났다. 흐름조건에 따른 매립토의 유실율은 살펴보면 두 가지 유사 모두 한계유속(Vc)을 넘어서는 순간, 급격히 유실율이 증가하였고, 일반모래는 약 10 % 안트라사이트는 약 30%로 각각 나타났다. 향후 매립토의 특성인자의 영향을 명확하게 구분하기 위해 다양한 매립토를 활용하여 보다 많은 조건하에서 실험을 수행한다면 매립토의 유실량 산정의 정확성을 높일 수 있을 것이라 기대된다.

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Low-Power Discrete-Event SoC for 3DTV Active Shutter Glasses (3DTV 엑티브 셔터 안경을 위한 저전력 이산-사건 SoC)

  • Park, Dae-Jin;Kwak, Sung-Ho;Kim, Chang-Min;Kim, Tag-Gon
    • Journal of the Institute of Electronics Engineers of Korea SP
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    • v.48 no.6
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    • pp.18-26
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    • 2011
  • Debates concerning the competitive edge of leading 3DTV technology of the shutter glasses (SG) 3D and the film-type patterned retarder (FPR) are flaring up. Although SG technology enables Full-HD 3D vision, it requires complex systems including the sync transmitter (emitter), the sync processor chip, and the LCD lens in the active shutter glasses. In addition, the transferred sync-signal is easily affected by the external noise and a 3DTV viewer may feel flicker-effect caused by cross-talk of the left and right image. The operating current of the sync processor in the 3DTV active shutter glasses is gradually increasing to compensate the sync reconstruction error. The proposed chip is a low-power hardware sync processor based discrete-event SoC(system on a chip) designed specifically for the 3DTV active shutter glasses. This processor implements the newly designed power-saving techniques targeted for low-power operation in a noisy environment between 3DTV and the active shutter glasses. This design includes a hardware pre-processor based on a universal edge tracer and provides a perfect sync reconstruction based on a floating-point timer to advance the prior commercial 3DTV shutter glasses in terms of their power consumption. These two techniques enable an accurate sync reconstruction in the slow clock frequency of the synchronization timer and reduce the power consumption to less than about a maximum of 20% compared with other major commercial processors. This article describes the system's architecture and the details of the proposed techniques, also identifying the key concepts and functions.