• Journal of Hospice and Palliative Care
• /
• 제24권3호
• /
• pp.144-153
• /
• 2021

Purpose: Advance care planning (ACP) is widely understood to improve end-of-life care. This systematic review and meta-analysis aimed to examine the effects of ACP interventions on decision conflict and psychological distress. Methods: A search of PubMed, CINAHL, CENTRAL, EMBASE, KISS, KoreaMed, and RISS was conducted in November 2020. The study included randomized controlled trials. Data were pooled using fixed- and random-effects models. Results: Fourteen studies were identified that cumulatively included 1,548 participants. ACP interventions were effective in alleviating decision conflict (d=-0.53; 95% CI: -0.83 to -0.23), depression (d=-1.22; 95% CI: -1.71 to -0.74) and anxiety (d=-0.76; 95% CI: -1.12 to -0.39). Conclusion: ACP interventions have significant positive effects on reducing decision conflict and psychological distress. A high level of bias was shown related to allocation concealment and blinding. The results of this study are expected to be useful for end-of-life care providers to improve the effectiveness of ACP interventions.

• 한국지반신소재학회논문집
• /
• 제15권4호
• /
• pp.25-32
• /
• 2016

지반공학에서 평면변형율을 가정하는 2차원 사면안정해석은 일반적으로 널리 사용되고 있다. 이 가정은 사면활동이 넓은 영역에 걸쳐서 발생되는 가정이므로 3차원 효과가 무시된다. 대다수 연구에서 2차원해석의 최소안전율값은 3차원해석에 비하여 작게 평가되는 보수적인 결과를 나타낸다. 최근에는 컴퓨터의 소프트웨어와 하드웨어를 포함한 해석방법의 발달로 3차원해석에 대한 요구가 커지고 있다. 본 논문에서는 원호모드, 병진모드사면을 이용하여 유한요소에 의한 2, 3차원해석 및 2차원 한계평형해석을 통하여 수치해석을 실시하였다. 해석결과 매개변수(요소망크기, 체적팽창각(dilatency angle), 경계조건, 응력이력, 모델차원)에 따른 사면안정해석에 미치는 영향을 분석하였다. 해석결과 2차원 해석보다 3차원 해석에 의한 사면의 안전율 값은 항상 크게 평가되며, W 뱡향 경계조건이 롤러지지인 경우, 사면폭에 의한 결과 차이는 없는 것으로 조사되었다.

• 대한수의학회지
• /
• 제37권3호
• /
• pp.669-685
• /
• 1997

The present study was performed to evaluate the effects of xylazine and tiletamine + zolazepam on echocardiograms before and after experimental myocardial infarctions in clinically normal dogs taken preliminary examinations related to cardiac function. The results are as follows. With xylazine administration, left ventricle end-diastolic dimension, left ventricle end-systolic dimension, left atrium/aorta, ejection time and velocity of circumferential fiber shortening increased and mitral valve CD slope, % delta D decreased(p<0.01). In tiletamine+zolazepam administered group, interventricular septum amplitude(p<0.01), mitral valve DE slope(p<0.05) and ejection time(p<0.01) decreased and left atrium/aorta, ejection time also decreased compared with xylazine group(p<0.01). In 48 hours after experimental myocardial infarction group, anterior aortic wall amplitude decreased compared with control, xylazine, tiletamine + zolazepam group, respectively(p<0.01). Posterior aortic wall amplitude decreased compared with control(p<0.01). Left ventricle end systolic dimension increased compared with control and tiletamine + zolazepam group, respectively(p<0.01). Left ventricular posterior wall end systolic dimension decreased compared with control(p<0.01). Left ventricular posterior wall amplitude decreased compared with control and tiletamine+zolazepam group(p<0.01). Left atrium/aorta decreased compared with xylazine group(p<0.01). % thickening left ventricular posterior wall decreased compared with control(p<0.05). % delta D decreased compared with control and tiletamine+zolazepam group(p<0.01). Ejection time decreased compared with xylazine(p<0.01). Velocity of circumferential fiber shortening increased compared with control and tiletamine + zolazepam group(p<0.01). With xylazine administration 48 hours after experimental myocardial infarction, anterior aortic wall amplitude, posterior aortic wall amplitude decreased compared with control(p<0.01). Left ventricle end-diastolic dimension increased compared with control(p<0.01). Left ventricle end-systolic dimension increased compared with control and tiletamine + zolazepam group, respectively(p<0.01). Left ventricular posterior wall end-systolic dimension and left ventricular posterior wall end-diastolic dimension decreased compared with control(p<0.01). Left atrium/aorta decreased compared with xylazine group(p<0.01). % thickening left ventricular posterior. wall(p<0.05) and % delta D(p<0.01) decreased compared with control. Velocity of circumferential fiber shortening increased compared with tiletamine + zolazepam group(p<0.01). With tiletamine + zolazepam administration 48 hours after experimental myocardial infarction, anterior aortic wall amplitude decreased compared with control, xylazine and tiletamine+zolazepam group, respectively(p<0.01). Posterior aortic wall amplitude decreased compared with control(p<0.01). Left ventricle end-systolic dimension increased compared with control and tiletamine+zolazepam group(p<0.01). Left ventricular posterior wall end-systolic dimension, left ventricular posterior wall end-diastolic dimension and interventricular septum amplitude decreased compared with control(p<0.01). Left atrium/aorta decreased compared with xylazine group(p<0.01). % delta D decreased compared with control and tiletamine + zolazepam group(p<0.01). Ejection time decreased compared with xylazine group and velocity of circumferential fiber shortening increased compared withtiletamine+zolazepam group(p<0.01). Conclusively, echocardiography was proved to be a useful, diagnostic, non-invasive and simple method for establishing the diagnosis of myocardial infarction and evaluating the effects of drug on cardiac function before and after myocardial infarction.

• 대한본초학회지
• /
• 제33권4호
• /
• pp.1-7
• /
• 2018

Objectives : Diabetic nephropathy is one of the most significant chronic complications of diabetes. Advanced glycation end products (AGEs) have been implicated in the development of diabetic nephropathy. GS-E3D is an enzymatic modified red ginseng extract by pectin lyase and has an increased concentration of the ginsenoside Rd compared to an unmodified red ginseng extract. In this study, we evaluated the preventive effects of GS-E3D on renal dysfunction in the type 2 diabetic db/db mice. Methods : GS-E3D (100 or 250 mg/kg body weight per day) was given to db/db mice through oral gavage for 6 weeks. Body weight and blood glucose levels were examined. At the end of the experiment, albuminuria was measured. The renal tissues were collected for histological examination, and immunohistochemical staining was used to detect renal accumulation of AGEs and podocyte loss Results : In the db/db mice, severe hyperglycemia developed, and albuminuria was significantly increased. Diabetes induced markedly morphological alterations to the renal glomerular cells. AGE accumulations and podocyte loss were detected in renal glomeruli. No difference in blood glucose levels was noted between GS-E3D-treated and vehicletreated diabetic db/db mice. However, GS-E3D treatment significantly reduced albuminuria and AGE accumulations in diabetic mice. Moreover, the loss of podocytes was restored by GS-E3D treatment. Conclusions : GS-E3D might be beneficial for the treatment of diabetic nephropathy. The ability of GS-E3D on to attenuate albuminuria and podocyte dysfunction in the db/db mice may be mediated by the inhibition of AGE accumulation.

• Computers and Concrete
• /
• 제13권3호
• /
• pp.411-421
• /
• 2014

A central pullout test was conducted to investigate the bonding properties between high strength rebar and reactive powder concrete (RPC), which covered ultimate pullout load, ultimate bonding stress, free end initial slip, free end slip at peak load, and load-slip curve characteristics. The effects of varying rebar buried length, thickness of protective layer and diameter of rebars on the bonding properties were studied, and how to determine the minimum thickness of protective layer and critical anchorage length was suggested according the test results. The results prove that: 1) Ultimate pull out load and free end initial slip load increases with increase in buried length, while ultimate bonding stress and slip corresponding to the peak load reduces. When buried length is increased from 3d to 4d(d is the diameter of rebar), after peak load, the load-slip curve descending segment declines faster, but later the load rises again exceeding the first peak load. When buried length reaches 5d, rebar pull fracture occurs. 2) As thickness of protective layer increases, the ultimate pull out load, ultimate bond stress, free end initial slip load and the slip corresponding to the peak load increase, and the descending section of the curve becomes gentle. The recommended minimum thickness of protective layer for plate type members should be the greater value between d and 10 mm, and for beams or columns the greater value between d and 15 mm. 3) Increasing the diameter of HRB500 rebars leads to a gentle slope in the descending segment of the pullout curve. 4) The bonding properties between high strength steel HRB500 and RPC is very good. The suggested buried length for test determining bonding strength between high strength rebars and RPC is 4d and a formula to calculate the critical anchorage length is established. The relationships between ultimate bonding stress and thickness of protective layer or the buried length was obtained.

• 대한물리의학회지
• /
• 제16권3호
• /
• pp.123-130
• /
• 2021

PURPOSE: Robotic gait training is being used increasingly to improve the gross motor performance and gait speed. The present study examined the effectiveness of a novel end-effector type of robotic gait training (RGT) system on standing, walking, running, and jumping functions, as well as the gait speed in children with spastic cerebral palsy. METHODS: Eleven children with spastic cerebral palsy Gross Motor Function Classification System (GMFCS) levels I-III (6 males; age range, 15.09 ± 1.44 years) were examined. They underwent 24 sessions (30 minutes/sessions, one time/day, three days/week for eight consecutive weeks) of RGT. The Gross Motor Function Measure-88 D domain (GMFM D), and GMFM E were assessed with a pretest and posttest of RGT. The setting was a one-group pretest-posttest design. RESULTS: A comparison of the pre-test and post-test show that the outcomes in post-test of GMFM D (p < .01), GMFM E (p < .05), and 10MWT were improved significantly after RGT intervention. CONCLUSION: The present study provided the first evidence on the effects of an eight-weeks RGT intervention in participants with spastic CP. The outcomes of this clinical study showed that standing performance, locomotion function, and gait speed increased in after 24 sessions of the end-effector RGT system in children with spastic cerebral palsy.

• 한국전자파학회지:전자파기술
• /
• 제24권2호
• /
• pp.35-50
• /
• 2013

This paper discusses effects of mesh planes on signal integrity in high-speed glass ceramic packages. One of serious signal integrity issues in high-speed glass ceramic packages is high far-end (FE) noise coupling between signal interconnects. Based on signal integrity analysis, a methodology is presented for reducing far-end noise coupling between signal interconnects in high-speed glass ceramic modules. This methodology employing power/ground mesh planes with alternating spacing and a via-connected coplanar-type shield (VCS) structure is suggested to minimize far-end noise coupling between signal lines in high-speed glass ceramic packages. Optimized interconnect structure based on this methodology has demonstrated that the saturated far-end noise coupling of a typical interconnect structure in glass ceramic modules could be reduced significantly by 73.3 %.

• Wind and Structures
• /
• 제30권5호
• /
• pp.533-546
• /
• 2020

Large Eddy Simulation (LES) is used to study the effects of steady slot suction on the aerodynamic forces of and flow around a wall-mounted finite-length square cylinder. The aspect ratio H/d of the tested cylinder is 5, where H and d are the cylinder height and width, respectively. The Reynolds number based on free-stream oncoming flow velocity U_∞ and d is 2.78×10⁴. The suction slot locates near the leading edge of the free end, with a width of 0.025d and a length of 0.9d. The suction coefficient Q (= U_s/U_∞) is varied as Q = 0, 1 and 3, where U_s is the velocity at the entrance of the suction slot. It is found that the free-end steady slot suction can effectively suppress the aerodynamic forces of the model. The maximum reduction of aerodynamic forces occurs at Q = 1, with the time-mean drag, fluctuating drag, and fluctuating lift reduced by 3.75%, 19.08%, 40.91%, respectively. For Q = 3, all aerodynamic forces are still smaller than those for Q = 0 (uncontrolled case), but obviously higher than those for Q = 1. The involved control mechanism is successfully revealed, based on the comparison of the flow around cylinder free end and the near wake for the three tested Q values.

• 대한전기학회:학술대회논문집
• /
• 대한전기학회 1996년도 하계학술대회 논문집 A
• /
• pp.172-174
• /
• 1996

In this paper, the characteristics of single-phase induction motors is studied using TDFE(Time Domain Finite Element) analysis. The magnetic field equation from the Maxwell's equations is solved using 2-Dimensional TDFE method, and the circuit equations from the stator and rotor are solved simultaneously. The 3-D effects, which are the end-leakage reactance and the resistance of end-rings are considered in 2-D combined equations. The proposed method is applied to the commercial single-phase induction motor. The calculated waveforms of the currents shows a good agreement with the measured ones.

• 대한기계학회논문집A
• /
• 제40권8호
• /
• pp.731-736
• /
• 2016

본 연구에서는 의용생체공학에 널리 사용되는 미소바늘과 같은 3차원 고종횡비 미소구조물을 용이하게 제작할 수 있는 하이브리드 자외선 노광법에 대해 기술한다. 하이브리드 자외선 노광법은 기존에 사용되고 있는 경사노광, 회전노광 및 역노광을 혼합한 방법으로, 경사 및 회전노광은 경사진 축대칭 형상을 가지는 3차원 미소구조물의 제작이 가능하도록 하고 역노광은 자외선 노광공정 중 필연적으로 발생하는 하부기판에서의 자외선 반사를 최소화 시킨다. 자체 개발한 자외선 노광시스템과 SU-8 음성감광제를 이용하여 하이브리드 자외선 노광법의 다양한 공정조건이 최종 제작된 3차원 고종횡비 미소구조물 형상(종횡비, 선단의 곡률반경 등)에 미치는 효과를 확인한다. 또한 SU-8의 소프트 베이킹(soft baking) 조건과 미소구조물 선단 형상 사이의 관계에 대해서도 논의한다.