• 제목/요약/키워드: 3D Morphology

검색결과 682건 처리시간 0.03초

한지 원재료인 닥나무와 인피섬유의 해부학적·화학적 특성 연구 (Anatomical, Morphological, and Chemical Characteristics of Paper-mulberry Wood and Bast Fiber for Raw Material of Korean Paper(Hanji))

  • 고인희;정선화
    • 보존과학회지
    • /
    • 제34권6호
    • /
    • pp.517-524
    • /
    • 2018
  • 본 연구는 닥나무의 삼단면 관찰을 통하여 공통된 해부학적 특성을 가지는지 확인하고 닥나무 인피섬유의 섬유장 폭, 내강폭과 같은 형태학적 특징과 화학적 특징을 통해 펄프, 제지공정에 영향을 미칠 수 있는 인자들을 분석하였다. 닥나무는 환공재, 반환공재이며 대도관이 고립관공으로 방사상배열이다. 접선단면 방사조직은 1~3열이고 나선비후가 관찰되어져 공통적으로 동일한 해부학적 특성이 나타났다. 인피섬유의 형태학적 특징으로는 섬유장 6.58~9.01 mm, 섬유폭 $15.85{\sim}27.80{\mu}m$, 내강폭 $4.50{\sim}12.54{\mu}m$로 나타났다. 펄프, 제지공정에 중요한 특성으로 여겨지는 runkel ratio, slenderness ratio 등을 고려했을 때 강원도 D시료가 가장 적합하였다. 인피섬유의 화학적 특성으로 경상도 C시료가 낮은 추출물 함량과 높은 셀룰로오스 함량을 가지는 것을 확인하였다. 섬유의 형태학, 화학적 특성은 한지 제조 후 품질을 결정하는 주요 인자의 기초자료로 활용될 것이다.

Saponins from Panax japonicus ameliorate age-related renal fibrosis by inhibition of inflammation mediated by NF-κB and TGF-β1/Smad signaling and suppression of oxidative stress via activation of Nrf2-ARE signaling

  • Gao, Yan;Yuan, Ding;Gai, Liyue;Wu, Xuelian;Shi, Yue;He, Yumin;Liu, Chaoqi;Zhang, Changcheng;Zhou, Gang;Yuan, Chengfu
    • Journal of Ginseng Research
    • /
    • 제45권3호
    • /
    • pp.408-419
    • /
    • 2021
  • Background: The decreased renal function is known to be associated with biological aging, of which the main pathological features are chronic inflammation and renal interstitial fibrosis. In previous studies, we reported that total saponins from Panax japonicus (SPJs) can availably protect acute myocardial ischemia. We proposed that SPJs might have similar protective effects for aging-associated renal interstitial fibrosis. Thus, in the present study, we evaluated the overall effect of SPJs on renal fibrosis. Methods: Sprague-Dawley (SD) aging rats were given SPJs by gavage beginning from 18 months old, at 10 mg/kg/d and 60 mg/kg/d, up to 24 months old. After the experiment, changes in morphology, function and fibrosis of their kidneys were detected. The levels of serum uric acid (UA), β2-microglobulin (β2-MG) and cystatin C (Cys C) were assayed with ELISA kits. The levels of extracellular matrix (ECM), matrix metalloproteinases (MMPs), tissue inhibitors of metalloproteinases (TIMPs), inflammatory factors and changes of oxidative stress parameters were examined. Results: After SPJs treatment, SD rats showed significantly histopathological changes in kidneys accompanied by decreased renal fibrosis and increased renal function; As compared with those in 3-month group, the levels of serum UA, Cys C and β2-MG in 24-month group were significantly increased (p < 0.05). Compared with those in the 24-month group, the levels of serum UA, Cys C and β2-MG in the SPJ-H group were significantly decreased. While ECM was reduced and the levels of MMP-2 and MMP-9 were increased, the levels of TIMP-1, TIMP-2 and transforming growth factor-β1 (TGF-β1)/Smad signaling were decreased; the expression level of phosphorylated nuclear factor kappa-B (NF-κB) was down-regulated with reduced inflammatory factors; meanwhile, the expression of nuclear factor erythroid 2-related factor 2-antioxidant response element (Nrf2-ARE) signaling was aggrandized. Conclusion: These results suggest that SPJs treatment can improve age-associated renal fibrosis by inhibiting TGF-β1/Smad, NFκB signaling pathways and activating Nrf2-ARE signaling pathways and that SPJs can be a potentially valuable anti-renal fibrosis drug.

3차원 도시공간정보를 이용한 도시열섬현상의 분석 (Analysis of Urban Heat Island Effect Using Information from 3-Dimensional City Model (3DCM))

  • 전범석;김학열
    • Spatial Information Research
    • /
    • 제18권4호
    • /
    • pp.1-11
    • /
    • 2010
  • 본 연구는 2차원적 도시특성변수를 이용한 기존 선행연구와 달리, 도시기하학적인 특성을 중심으로 도시열섬현상에 관한 설명모형을 구축하고 이에 대한 정책적 시사점을 제시하고 자하는 연구이다. 오하이오주 콜럼버스 도시(Columbus, Ohio)의 3차원 도시공간구축을 위하여 LiDAR 데이터가 활용되었고, 건축물의 외부공간을 구축하기 위하여 건물수치지도가 이용되었다. 또한 식생지수와 도시온도 자료를 추출하기 위하여 Landsat TM 영상의 band 3, band 4, Thermal band 가 이용되었다. 복잡한 자료 추출 과정을 통해 획득된 6가지 변수들(건물의 총 부피, 건물의 총 표면적, 평균 건물의 높이-도로폭 비율, 공극률, 건물바닥면적비율, 식생지수)을 도입하여 단순회귀 및 다중회귀 모형을 구축하였다. 회귀모형구축에 있어서는 비선형관계에 있는 변수를 선형화하기 위해 Box-Tidwell 변형기법을 적용하였으며 최적화된 변수변형을 통한 선형회귀모형을 구축하였다. 공극률, 식생지수, 건축 표면적 변수로 추정된 다중회귀모형은 전체 온도변이의 57%를 설명할 수 있는 것으로 나타났으며, 도시열섬을 저감시키기 위한 다양한 정책수립(오픈스페이스 확대정책, 옥상녹화, 벽면녹화 등)에 의미있는 결과를 제공하였다.

EC : MA 혼합전해질에서 카본 전극의 용량 특성 II. 초기 비가역 용량에 대한 첨가제의 효과 (Properties of Capacity on Carbon Electrode in EC : MA Electrolyte II. Effect of Additives on Initial Irreversible Capacity)

  • 박동원;김우성;손동언;최용국
    • 공업화학
    • /
    • 제17권6호
    • /
    • pp.575-579
    • /
    • 2006
  • 리튬의 삽입과 탈리가 가능한 탄소전극은 첫 싸이클 동안 카본전극 계면에 solid electrolyte interface가 형성된다. 초기 충전과정에서의 용매분해로 형성된 막은 전지의 성능에 영향을 미치게 되며, 이러한 용매분해는 초기 비가역 용량의 주된 요인중의 하나이다. 본 연구에서는 초기 비가역 반응을 억제하기위해 카본 표면 위에 부동태 막 형성을 위한 첨가제로서 $Li_{2}CO_{3}$을 사용하였다. $Li_{2}CO_{3}$ 첨가 효과를 시간대 전압법, 순환 전압-전류법, 그리고 임피던스법을 이용하여 조사하였고, 또한 SEM, EDX 그리고 XRD를 통해 표면 현상과 조성의 변화를 관찰하였다. 1 M $LiPF_{6}$/EC : MA (1 : 3, v/v) 전해질 용액에 $Li_{2}CO_{3}$의 첨가는 전극 표면에서의 용매분해 억제를 통하여 초기 비가역 용량을 감소시킴을 확인하였다.

Effects of Alfalfa Meal on Growth Performance and Gastrointestinal Tract Development of Growing Ducks

  • Jiang, J.F.;Song, X.M.;Huang, X.;Zhou, W.D.;Wu, J.L.;Zhu, Z.G.;Zheng, H.C.;Jiang, Y.Q.
    • Asian-Australasian Journal of Animal Sciences
    • /
    • 제25권10호
    • /
    • pp.1445-1450
    • /
    • 2012
  • A study was conducted to evaluate effects of alfalfa meal on growth performance and gastrointestinal tract development of growing layer ducks to provide evidence for application of alfalfa meal in the duck industry. Two hundred and fifty-six healthy Shaoxing 7-wk old growing layer ducks were selected and randomly allocated to 1 of 4 dietary treatments based on corn and soybean meal and containing 0, 3, 6, and 9% of alfalfa meal for 8 wks. Each treatment consisted of 4 replicates of 16 ducks each. Briefly, birds were raised in separate compartments, and each compartment consisted of three parts: indoor floor house, adjacent open area and a connecting water area. The results showed: i) Growing ducks fed alfalfa meal diet were not significantly different in average daily gain, feed intake and gain-to-feed ratio from those fed no alfalfa diet (p>0.05). ii) Alfalfa meal increased the ratio crop, gizzard to live weight, caecum to live weight, the caecum index of growing ducks (p<0.05). iii) Villus height in duodenum and jejunum of growing ducks increased significantly with the increase of alfalfa meal levels (p<0.05). Crypt depth in duodenum and jejunum of growing ducks decreased significantly with the increase of alfalfa meal levels (p<0.05). This experiment showed that feeding of alfalfa meal to growing layer ducks could improve gastrointestinal tract growth and small intestinal morphology without effect on performance. This experiment provides evidence that alfalfa meal is a very valuable feedstuff for growing layer ducks.

바닥면상태에 따른 심장세포의 수축력 변화 (The dependence of contractile force for the cardiomyocytes on a different engineered surface)

  • 김진석;박정렬;류석규;백정은;차정훈;박세완;김현철;김병규;박석호;전국진
    • 대한전자공학회:학술대회논문집
    • /
    • 대한전자공학회 2005년도 추계종합학술대회
    • /
    • pp.881-884
    • /
    • 2005
  • We present a microfabricated three-dimensional (3-D) hybrid biopolymer micro cantilever which can measure the contractile force of cardiomyocytes and analyze the force dependence on different types of surface. To make different conditions of the cell seeding surface, we fabricated the specific type of cantilever which was grooved on the surface. The presented cantilever was facilitated to measure bending of the cantilever and to calculate the contractile force of cardiomyocytes. Also, we demonstrate the dependence of the morphology for the cardiomyocytes seeded on a plain surface and a grooved surface. Finally, we show the dependence of force for the cardiomyocytes on a different surface.

  • PDF

Sol-gel 법을 이용한 내오염 반사방지 코팅막 제조 (Fabrication of Hydrophobic Anti-Reflection Coating Film by Using Sol-gel Method)

  • 김정엽;이지선;황종희;임태영;이미재;현승균;김진호
    • 한국재료학회지
    • /
    • 제24권12호
    • /
    • pp.689-693
    • /
    • 2014
  • Anti-reflection coating films have used to increase the transmittance of displays and enhance the efficiency of solar cells. Hydrophobic anti-reflection coating films were fabricated on a glass substrate by sol-gel method. To fabricate an anti-reflection film with a high transmittance, poly ethylene glycol (PEG) was added to tetraethyl orthosilicate (TEOS) solution. The content of PEG was changed from 1 to 4 wt% in order to control the morphology, thickness, and refractive index of the $SiO_2$ thin films. The reflectance and transmittance of both sides of the coated thin film fabricated with PEG 4 wt% solution were 0.3% and 99.4% at 500 nm wavelength. The refractive index and thickness of the thin film were n = 1.29 and d = 105 nm. Fluoro alkyl silane (FAS) was used for hydrophobic treatment on the surface of the anti-reflection thin film. The contact angle was increased from $13.2^{\circ}$ to $113.7^{\circ}$ after hydrophobic treatment.

이차전지용 미세다공성 PVdF 분리막의 제조와 물성 (Preparation and Characterization of Microporous PVdF Membrane for Li-ion Rechargeable Battery)

  • 남상용;유대현;정미애;임지원;변홍식;정철호;이영무;서명수
    • 멤브레인
    • /
    • 제17권3호
    • /
    • pp.233-243
    • /
    • 2007
  • 본 연구에서는 충전용 이차전지의 분리막으로 쓰이는 다공성 막을 기존의 분리막 재료보다 뛰어난 물성을 나타내는 PVdF(poly(vinylidene fluoride))를 사용하여 상전이 방법으로 제조하였다. 용매인 DMF(N,N-dimethylformamide)에 PVdF를 단일상으로 녹인 후 깨끗한 유리판에 캐스팅하여 막을 얻었다. 얻어진 분리막에서 가장 높은 공극률은 78.6%로 얻어졌다. UTM(universal testing machine)을 이용하여 측정된 분리막의 인장강도는 PVdF 20 wt%에서 5.16 MPa의 값을 나타내었다. 시차주사현미경(scanning electron microscopy, SEM)을 이용하여 분리막의 단면 관찰을 통해 다공성을 확인하였다.

쥐가오리 모방 진동식 조류 터빈의 출력향상에 대한 실험적 연구 (Experimental Study on Power Improvement of a Flapping Tidal Stream Turbine by Mimicking a Manta-Ray)

  • 고진환;김지훈
    • Ocean and Polar Research
    • /
    • 제39권4호
    • /
    • pp.293-300
    • /
    • 2017
  • Various approaches have been tried in an effort to improve the power performance of a flapping tidal stream turbine after it was introduced as an alternative to conventional rotary turbines. Among the different approaches, researches on mimicking the morphology and behavior of animals have been conducted. In this study, we utilized a flapper to mimic the multi-joint pectoral fin of a Manta-ray and investigated its effect on power generation. Experiments were conducted by a dual flapping apparatus with rigid and flexible flappers in a towing tank facility. First, in order to determine the conditions that can produce high power generation, the performances of the dual rigid flappers were compared when input arm angles and frequencies are changed, and the two conditions $40^{\circ}$, 0.2 Hz and $40^{\circ}$, 0.3 Hz for the input arm angle, frequency were selected. When the mimicked flexible flapper was used instead of the front rigid flapper and the rear one, the power was improved by an average of 22% and 38% in the experimental conditions, respectively. Moreover, it was recognized from the apparent camber observed during the experiment that the flexible flapper had been successfully applied. If the feasibility of the Manta-Ray mimicked flapper is improved through subsequent researches, the flapping tidal turbine can be a viable alternative to rotary turbines in the near future.

탈세포화 기법을 이용한 돼지 바이오 스캐폴드: 환자 맞춤형 장기재생을 위한 역분화 줄기세포 동물모델 (Decellularized Bioscaffold of Pig Organs: A Tool for Patient-specific Organogenesis Using Induced Pluripotent Stem Cells)

  • 박경미;곽호현;남현숙;박인철;전용환;박성민;이승태;우제석;우흥명
    • 한국임상수의학회지
    • /
    • 제28권1호
    • /
    • pp.57-62
    • /
    • 2011
  • The shortage of transplantable kidneys has many efforts to regenerate bioartificial kidneys using transgenic animals and diverse kinds of scaffolds which are important tools for cell seeding. However, there are many limitations for clinical applications so far. Recently, decellularized bioscaffolds using animal organs come into spotlight because of its many superior advantages. In current study, we produced decellularized kidney bioscaffolds of pig which is an attractive animal as a clinical model for human. We decellularized pig kidneys with 1% SDS detergent solution using peristaltic pump systems for 12h. After decellularization process, the kidney bioscaffolds preserved intact 3D morphology including glomerular structure and almost DNA from pig was entirely removed. In addition, this process could preserve micro vascular network which is necessary for cell survival. Although, additional studies for recellularization and transplantation should be required, the decellular vascularized kidney bioscaffolds might have many potentials for kidney regeneration.