Proceedings of the IEEK Conference (대한전자공학회:학술대회논문집)

The Institute of Electronics and Information Engineers (대한전자공학회)
권호 표지

The dependence of contractile force for the cardiomyocytes on a different engineered surface

바닥면상태에 따른 심장세포의 수축력 변화

  • Kim, Jin-Seok (School of Electrical Engineering, Seoul National University, Microsystem Research Center, Korea Institute of Science and Technology) ;
  • Park, Jung-Yul (Microsystem Research Center, Korea Institute of Science and Technology) ;
  • Ryu, Suk-Kyu (Microsystem Research Center, Korea Institute of Science and Technology) ;
  • Baek, Jeong-Eun (Microsystem Research Center, Korea Institute of Science and Technology) ;
  • Cha, Jung-Hun (School of Electrical Engineering, Seoul National University) ;
  • Park, Se-Wan (School of Electrical Engineering, Seoul National University) ;
  • Kim, Hyeon-Chul (School of Electrical Engineering, Seoul National University) ;
  • Kim, Byung-Kyu (The School of Aerospace and Mechanical Engineering, Hankuk Aviation University) ;
  • Park, Suk-Ho (Microsystem Research Center, Korea Institute of Science and Technology) ;
  • Chun, Kuk-Jin (School of Electrical Engineering, Seoul National University)
  • 김진석 (서울대학교 공과대학 전기컴퓨터공학부, 한국과학기술연구원 마이크로시스템연구센터) ;
  • 박정렬 (한국과학기술연구원 마이크로시스템연구센터) ;
  • 류석규 (한국과학기술연구원 마이크로시스템연구센터) ;
  • 백정은 (한국과학기술연구원 마이크로시스템연구센터) ;
  • 차정훈 (서울대학교 공과대학 전기컴퓨터공학부) ;
  • 박세완 (서울대학교 공과대학 전기컴퓨터공학부) ;
  • 김현철 (서울대학교 공과대학 전기컴퓨터공학부) ;
  • 김병규 (한국항공대학교, 항공우주 및 기계공학부) ;
  • 박석호 (한국과학기술연구원 마이크로시스템연구센터) ;
  • 전국진 (서울대학교 공과대학 전기컴퓨터공학부)
  • Published : 2005.11.26
Download PDF
⟨ Previous Next ⟩

Abstract

We present a microfabricated three-dimensional (3-D) hybrid biopolymer micro cantilever which can measure the contractile force of cardiomyocytes and analyze the force dependence on different types of surface. To make different conditions of the cell seeding surface, we fabricated the specific type of cantilever which was grooved on the surface. The presented cantilever was facilitated to measure bending of the cantilever and to calculate the contractile force of cardiomyocytes. Also, we demonstrate the dependence of the morphology for the cardiomyocytes seeded on a plain surface and a grooved surface. Finally, we show the dependence of force for the cardiomyocytes on a different surface.

Keywords