• Journal of the Korean Geotechnical Society
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• v.39 no.8
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• pp.17-28
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• 2023

Laboratory-scale hydraulic fracturing experiments were conducted on granite specimens at various viscosities and injection rates of the fracturing fluid. A series of cross-sectional computed tomography (CT) images of fractured specimens was obtained via a three-dimensional X-ray CT imaging method. Pixel-level fracture segmentation of the CT images was conducted using a convolutional neural network (CNN)-based Nested U-Net model structure. Compared with traditional image processing methods, the CNN-based model showed a better performance in the extraction of thin and complex fractures. These extracted fractures extracted were reconstructed in three dimensions and morphologically analyzed based on their fracture volume, aperture, tortuosity, and surface roughness. The fracture volume and aperture increased with the increase in viscosity of the fracturing fluid, while the tortuosity and roughness of the fracture surface decreased. The findings also confirmed the anisotropic tortuosity and roughness of the fracture surface. In this study, a CNN-based model was used to perform accurate fracture segmentation, and quantitative analysis of hydraulic stimulated fractures was conducted successfully.

• Molecules and Cells
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• v.24 no.3
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• pp.441-444
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• 2007

Despite the importance of cell fate decisions regulated by epigenetic programming, no experimental model has been available to study transdifferentiation from myoblasts to smooth muscle cells. In the present study, we show that myoblast cells can be induced to transdifferentiate into smooth muscle cells by modulating their epigenetic programming. The DNA methylation inhibitor, zubularine, induced the morphological transformation of C2C12 myoblasts into smooth muscle cells accompanied by de novo synthesis of smooth muscle markers such as smooth muscle ${\alpha}$-actin and transgelin. Furthermore, an increase of p21 and decrease of cyclinD1 mRNA were observed following zebularine treatment, pointing to inhibition of cell cycle progression. This system may provide a useful model for studying the early stages of smooth muscle cell differentiation.

• Journal of the Korean Society of Visualization
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• v.19 no.3
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• pp.115-122
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• 2021

Oral cancer surgery typically consists of resection of lesion, neck dissection and reconstruction, and it has an impact on the position of hyoid bone. Therefore, morphological change of airway can occur since the geometric parameter of airway is correlated with the hyoid bone. Airflow is affected by geometry of the airway. In this study, flow characteristics were compared between pre- and post-surgery models by both particle image velocimetry (PIV) and numerical simulation. 3D model of upper airway was reconstructed based on CT data. Velocity is accelerated by the reduced channel area, and vortex and recirculation region are observed in pre- and post-surgery models. For the post-surgery model, high pressure distribution is developed by significantly decreased hydraulic diameter, and the longitudinal flow stream is also interrupted.

• Korean Journal of Remote Sensing
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• v.8 no.2
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• pp.131-145
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• 1992

A low cost personal computer and image processing S/W were empolyed to derive Digtal Elevation Model(DEM) of tidal flat from multitemporal LANDSAT TM images, and to create three-dimensional(3D) perspective views of the tidel flat on Komso bay in west coasts of Korea. The method for generation of Digital Elevation Model(DEM) in tidal flat was considered by overlapping techniques of multitemporal LANDSAT TM images and interpolations. The boundary maps of tidal flat extracted from multitemporal images with different water high were digitally combined in x, y, z space with tide in formation and used as an inputcontour data to obtain an elevation model by interpolation using spline function. Elevation errors of less than $\pm$0.1m were achived using overlapping techniques and a spline interpolation approach, respectively. The derived DEM allows for the generation of a perspective grid and drape on the satellite image values to create a realistic terrain visualization model so that the tidal flat may be viewed from and desired direction. As the result of this study, we obtained elevation model of tidal flats which contribute to characterize of topography and monitoring of morphological evolution of tidal flats. Moreover, the modal generated here can be used for simulation of innudation according to tide and support other studies as a supplementary data set.

• Journal of Wetlands Research
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• v.13 no.1
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• pp.79-94
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• 2011

As demonstrated in study for non-submerged groynes, the flow field is predominantly two-dimensional, with mainly horizontal eddies. The eddies shed form the tips of the groynes and migrate in the flow direction. These eddies have horizontal dimensions in the order of tens of meters and time-scales in the order of minutes. In the standard flow simulations, these motions are usually not resolved, due to a too coarse grid, too large time steps and, more importantly, the use of inadequate turbulence modelling. using for example a k-${\varepsilon}$ model, it is necessary to introduce substantial modifications. Therefore simulation resolved in this study, were carried out using the DELFT-3D-MOR programme, which is part of the DELFT3D software package of WL/Delft Hydraulics and In this study, apply a two-dimensional depth-averaged model, taking an horizontal large eddy simulation(HLES). The bed morphology computed when using HLES, as well as the associated time-scale, is similar to what has been obseved in a field case. When using a mean-flow model with-out HELS, the bed morphology is less realistic and the morphological time-scale is much larger. This slow development is the result of neglecting(or averaging). the strong velocity fluctuations associated with the time-varying eddy formation.

• Journal of Radiation Protection and Research
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• v.47 no.3
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• pp.143-151
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• 2022

Background: After the Fukushima Daiichi Nuclear Power Plant (FDNPP) accident, biological alterations in the natural biota, including morphological changes of fir trees in forests surrounding the power plant, have been reported. Focusing on the terminal buds involved in the morphological formation of fir trees, this study developed a method for estimating the absorbed radiation dose rate using radionuclide distribution measurements from tree organs. Materials and Methods: A phantom composed of three-dimensional (3D) tree organs was constructed for the three upper whorls of the fir tree. A terminal bud was evaluated using Monte Carlo simulations for the absorbed dose rate of radionuclides in the tree organs of the whorls. Evaluation of the absorbed dose targeted ¹³¹I, ¹³⁴Cs, and ¹³⁷Cs, the main radionuclides subsequent to the FDNPP accident. The dose contribution from each tree organ was calculated separately using dose coefficients (DC), which express the ratio between the average activity concentration of a radionuclide in each tree organ and the dose rate at the terminal bud. Results and Discussion: The dose estimation indicated that the radionuclides in the terminal bud and bud scale contributed to the absorbed dose rate mainly by beta rays, whereas those in 1-year-old trunk/branches and leaves were contributed by gamma rays. However, the dose contribution from radionuclides in the lower trunk/branches and leaves was negligible. Conclusion: The fir tree model provides organ-specific DC values, which are satisfactory for the practical calculation of the absorbed dose rate of radiation from inside the tree. These calculations are based on the measurement of radionuclide concentrations in tree organs on the 1-year-old leader shoots of fir trees. With the addition of direct gamma ray measurements of the absorbed dose rate from the tree environment, the total absorbed dose rate was estimated in the terminal bud of fir trees in contaminated forests.

• Journal of the Korean Society of Surveying, Geodesy, Photogrammetry and Cartography
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• v.38 no.3
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• pp.237-246
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• 2020

Recently, as high resolution satellites data have been serviced, frequent DSM (Digital Surface Model) generation over urban areas has been possible. In addition, it is possible to detect changes using a high-resolution DSM at building level such that various methods of building change detection using DSM have been studied. In order to detect building changes using DSM, we need to generate a DSM using a stereo satellite image. The change detection method using D-DSM (Differential DSM) uses the elevation difference between two DSMs of different dates. The D-DSM method has difficulty in applying a precise vertical threshold, because between the two DSMs may have elevation errors. In this study, we focus on the urban structure change detection using D-nDSM (Differential nDSM) based on nDSM (Normalized DSM) that expresses only the height of the structures or buildings without terrain elevation. In addition, we attempted to reduce noise using a morphological filtering. Also, in order to improve the roadside buildings extraction precision, we exploited the urban road network extraction from nDSM. Experiments were conducted for high-resolution stereo satellite images of two periods. The experimental results were compared for D-DSM, D-nDSM, and D-nDSM with road extraction methods. The D-DSM method showed the accuracy of about 30% to 55% depending on the vertical threshold and the D-nDSM approaches achieved 59% and 77.9% without and with the morphological filtering, respectively. Finally, the D-nDSM with the road extraction method showed 87.2% of change detection accuracy.

• Composites Research
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• v.37 no.2
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• pp.59-67
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• 2024

Research was conducted on a PA material-based composite material manufacturing method for application to engine mount brackets. Engine mount brackets must have heat resistance, impact resistance, and damping performance. PA66 resin was used as the base material for the composite material. The glass fiber was used as the reinforcement material. The composite material was manufactured using the injection molding method. The thermal, mechanical, and morphological characteristics were analyzed depending on the content of glass fiber. 3D model was created using the property evaluation database of composite materials(input data). The damping performance of the generated 3D model was extracted as out-put data. The reason for evaluating the characteristics of PA-based composite materials and conducting simulations on the damping performance of 3D models of engine brackets is because product performance can be predicted without manufacturing actual automobile parts and conducting damping performance tests. As a result of the damping simulation, damping performance tended to increase proportionally as the mass fraction of the reinforcement increased. But above a certain level, it no longer increased and slightly decreased. As a result of comparing the actual experimental values a nd the simulated values, the approximate value was within ±5%.

• Journal of Microbiology and Biotechnology
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• v.3 no.3
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• pp.209-213
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• 1993

The flow behavior of the mycelial broth of glucoamylase hyperproducer Asp. niger No. PFST-38 for the production of glucoamylase were studied. The mycelial broth followed Bingham-pseudoplastic flow model described by Herschel-Bulkley equation. The yield stress increased with the increase in mycelial concentration. The dependency of the consistency index and the flow behavior index on the mycelial concentration could be expressed by a linear relationship. The consistency index increased proportionally with the mycelial concentration while the flow behavior index decreased with the increase in mycelial concentration. The flow property of the broth was related to the morphological data obtain in the previous study. The changes in apparent viscosity of the broth could be expressed as a function of the hyphal thickness as shown below.

• Food Science of Animal Resources
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• v.41 no.4
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• pp.623-635
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• 2021

The effect of deer antler extract on muscle differentiation and muscle atrophy were evaluated to minimize muscle loss following aging. Various deer antler extracts (HWE, hot water extract of deer antler; FE, HWE of fermented deer antler; ET, enzyme-assisted extract of deer antler; UE, extract prepared by ultrasonication of deer antler) were evaluated for their effect on muscle differentiation and inhibition of 5-aminoimidazole-4-carboxamide ribonucleoside (AICAR)-induced muscle atrophy in C2C12 cells. Morphological changes according to the effect of antler extracts on muscle differentiation were confirmed by Jenner-Giemsa staining. In addition, the expression levels of genes related to muscle differentiation and atrophy were confirmed through qRT-PCR. In the presence of antler extracts, the length and thickness of myotubes and myogenin differentiation 1 (MyoD1) and myogenic factor 5 (Myf5) gene expression were increased compared to those in the control group (CON). Gene expression of AMP-activated protein kinase (AMPK), MyoD1, and myogenin, along with the muscle atrophy factors muscle RING finger-1 (MuRF-1) and forkhead box O3a (FoxO3a) upon addition of deer antler extracts to muscle-atrophied C2C12 cells was determined by qRT-PCR after treatment with AICAR. The expression of MuRF-1 and FoxO3a decreased in the groups treated with antler extracts compared to that in the group treated with AICAR alone. In addition, gene expression of MyoD1 and myogenin in the muscle atrophy cell model was significantly increased compared that into the CON. Therefore, our findings indicate that antler extract can increase the expression of MyoD1, Myf5 and myogenin, inhibit muscle atrophy, and promote muscle differentiation.