• Journal of the Korean Society of Radiology
• /
• v.16 no.6
• /
• pp.709-718
• /
• 2022

We evaluated the effect of high-density aluminum, titanium, and steel metal inserts on computed tomography (CT) numbers and radiation treatment plans for Tomotherapy. CT images were obtained using a cylindrical TomoPhantom comprising cylindrical rods of various densities and metal inserts. Three CT image sets were evaluated for image quality as the mean CT number and standard deviation. Dose evaluation also performed. The reference values did not significantly differ between the CT image sets with the corrected metal inserts. The higher-density material exhibited the largest difference in the mean CT number and standard deviation. The conformity index at Iterative-Metal Artifact Reduction (iMAR) was approximately 20% better than that of non-iMAR. No significant target or organ at risk dose difference was observed between non-iMAR and iMAR. Therefore, iMAR is helpful for target or organ at risk delineation and for reducing uncertainty for three-dimensional conformal radiation therapy in Tomotherapy.

• Journal of the Korean Geotechnical Society
• /
• v.39 no.8
• /
• pp.17-28
• /
• 2023

Laboratory-scale hydraulic fracturing experiments were conducted on granite specimens at various viscosities and injection rates of the fracturing fluid. A series of cross-sectional computed tomography (CT) images of fractured specimens was obtained via a three-dimensional X-ray CT imaging method. Pixel-level fracture segmentation of the CT images was conducted using a convolutional neural network (CNN)-based Nested U-Net model structure. Compared with traditional image processing methods, the CNN-based model showed a better performance in the extraction of thin and complex fractures. These extracted fractures extracted were reconstructed in three dimensions and morphologically analyzed based on their fracture volume, aperture, tortuosity, and surface roughness. The fracture volume and aperture increased with the increase in viscosity of the fracturing fluid, while the tortuosity and roughness of the fracture surface decreased. The findings also confirmed the anisotropic tortuosity and roughness of the fracture surface. In this study, a CNN-based model was used to perform accurate fracture segmentation, and quantitative analysis of hydraulic stimulated fractures was conducted successfully.

• Journal of the Korean Association of Oral and Maxillofacial Surgeons
• /
• v.50 no.4
• /
• pp.197-205
• /
• 2024

Objectives: To evaluate the effectiveness of decompression and various parameters that may affect volume change in cystic lesions. Patients and Methods: This retrospective study included patients who visited the Department of Oral and Maxillofacial Surgery at Ewha Womans University Medical Center between 2012 and 2022 for decompression of cystic lesions of the jaw. To measure volume changes, pre- and post-decompression cone-beam computed tomography was performed and reconstructed in three dimensions using Mimics 25.0 software (Materialise NV). A comparative analysis was performed based on sex, age, initial cyst volume, location, degree of cortical layer expansion, and pathologic diagnosis using the Mann-Whitney U and Kruskal-Wallis tests. Results: In all 20 cases, the duration of decompression was 7.84±3.35 months, and all patients successfully completed the decompression period without any complications. Significant differences were observed in the reduction rate and shrinkage speed based on the degree of cortical layer expansion. However, only the shrinkage speed (not the reduction rate) showed a significant difference with respect to the initial cyst volume. Significant differences were not observed based on sex, age, location, or pathologic diagnosis. Conclusion: Although the present study involved a small number of cases, the effectiveness of decompression was confirmed. In particular, 3D analysis overcame the shortcomings of previous studies of decompression and allowed earlier resection. Further studies with more patients are required to provide a rationale for these results and identify factors that influence decompression.

• Journal of the Korean GEO-environmental Society
• /
• v.17 no.7
• /
• pp.15-25
• /
• 2016

In the present work, a number of advanced three-dimensional (3D) parametric finite element numerical analyses have been conducted to study the behaviour of single piles and pile groups in consolidating ground from coupled consolidation analyses. Single piles, $4{\times}4$ and $6{\times}6$ piles inside groups with a spacing of 2.5D were considered, where D is the pile diameter. It has been found that dragload and downdrag on the piles developed rather quickly at the early stage of consolidation. However, when the degree of consolidation was more than 50~75%, only little increases of dragload and downdrag were induced on the pile. Negative Skin Friction (NSF) on the pile in the fill layer was mobilised quickly and remained constant throughout further consolidation. The development of NSF is influenced both by the relative shear displacements at the pile-soil interface and the vertical effective soil stresses during consolidation. The former governed the early stage of consolidation and the latter affected the later stage of consolidation. The vertical effective soil stresses adjacent to the piles were reduced due to the shear stress transfer at the pile-soil interface, in particular for piles inside the pile groups. The range of NSF influence zone concerning the reductions of the effective vertical soil stresses was about 20D measured from the piles in the horizontal direction. On the contrary, the effective horizontal soil stresses acting on the piles were similar to those at the far field.

• Journal of the Korean Geotechnical Society
• /
• v.31 no.5
• /
• pp.35-46
• /
• 2015

In this study, the behavior of self-supported earth retaining wall with stabilizing piles was investigated by using a numerical study and field tests in urban excavations. This earth retaining wall can provide stable support against lateral earth pressures through its use of stabilizing piles that provide passive resistance to lateral earth pressures arising due to ground excavations. Field tests at two sites were performed to verify the performance of instrumented retaining wall with stabilizing piles. Furthermore, detailed 3D numerical analyses were conducted to provide insight into the in situ wall behavior. The 3D numerical methodology in the present study represents the behavior of the self-supported earth retaining wall with stabilizing piles. A number of 3D numerical analyses were carried out on the self-supported earth retaining wall with stabilizing piles to assess the results stemming from wide variations of influencing parameters such as the soil condition, the pile spacing, the distance between the front pile and the rear pile, and the pile embedded depth. Based on the results of the parametric study, the maximum horizontal displacement and the maximum bending moment significantly decreased when the retaining wall with stabilizing piles is used. Moreover, the horizontal displacement reduction effect of influencing parameters such as the pile spacing and the distance between the front pile and the rear pile is more sensitive in sandy soil, with a higher friction angle compared to clayey soil. In engineering practice, reducing the pile spacing and increasing the distance between the front pile and the rear pile can effectively improve the stability of the self-supported earth retaining wall with stabilizing piles.

• Journal of radiological science and technology
• /
• v.40 no.1
• /
• pp.63-70
• /
• 2017

The purpose of this study was compare to the patient setup deviation of two different type thermoplastic immobilization masks for glottis cancer in the intensity-modulated radiation therapy (IMRT). A total of 16 glottis cancer cases were divided into two groups based on applied mask type: standard or alternative group. The mean error (M), three-dimensional setup displacement error (3D-error), systematic error (${\Sigma}$), random error (${\sigma}$) were calculated for each group, and also analyzed setup margin (mm). The 3D-errors were $5.2{\pm}1.3mm$ and $5.9{\pm}0.7mm$ for the standard and alternative groups, respectively; the alternative group was 13.6% higher than the standard group. The systematic errors in the roll angle and the x, y, z directions were $0.8^{\circ}$, 1.7 mm, 1.0 mm, and 1.5 mm in the alternative group and $0.8^{\circ}$, 1.1 mm, 1.8 mm, and 2.0 mm in the alternative group. The random errors in the x, y, z directions were 10.9%, 1.7%, and 23.1% lower in the alternative group than in the standard group. However, absolute rotational angle (i.e., roll) in the alternative group was 12.4% higher than in the standard group. For calculated setup margin, the alternative group in x direction was 31.8% lower than in standard group. In contrast, the y and z direction were 52.6% and 21.6% higher than in the standard group. Although using a modified thermoplastic immobilization mask could be affect patient setup deviation in terms of numerical results, various point of view for an immobilization masks has need to research in terms of clinic issue.

• The Journal of Korean Institute of Communications and Information Sciences
• /
• v.38C no.12
• /
• pp.1196-1206
• /
• 2013

In this paper, based on the information about navigation system of UAV with PTZ camera and 3D topography, algorithm able to show us in real-time UAV's geographical shooting location and automatically calculate superficial measure of the shooting area is proposed. And the method that can automatically estimate whether UAV is allowed to shoot a specific area is shown. In case of an UAV's shooting attempt at the specific area, obtainability of valid image depends on not only UAV's location but also information of 3D topography. As a result of the study, Ground Control Center will have real-time information about whether UAV can shoot the needed topography. Therefore, accurate remote flight control will be possible in real-time. Furthermore, the algorithm and the method of estimating shooting probability can be applied to pre-flight simulation and set of flight route.

• Journal of Institute of Control, Robotics and Systems
• /
• v.8 no.9
• /
• pp.776-787
• /
• 2002

Automation of welding process in shipyards is ultimately necessary, since the welding site is spatially enclosed by floors and girders, and therefore welding operators are exposed to hostile working conditions. To solve this problem, a welding mobile robot that can navigate autonomously within the enclosure has been developed. To achieve the welding task in the closed space, the robotic welding system needs a sensor system for the working environment recognition and the weld seam tracking, and a specially designed environment recognition strategy. In this paper, a three-dimensional laser vision system is developed based on the optical triangulation technology in order to provide robots with 3D work environmental map. Using this sensor system, a spatial filter based on neural network technology is designed for extracting the center of laser stripe, and evaluated in various situations. An environment modeling algorithm structure is proposed and tested, which is composed of the laser scanning module for 3D voxel modeling and the plane reconstruction module for mobile robot localization. Finally, an environmental recognition strategy for welding mobile robot is developed in order to recognize the work environments efficiently. The design of the sensor system, the algorithm for sensing the partially structured environment with plane segments, and the recognition strategy and tactics for sensing the work environment are described and discussed with a series of experiments in detail.

• Bulletin of the Korean Chemical Society
• /
• v.34 no.7
• /
• pp.1972-1984
• /
• 2013

Microtubules play an important role in intracellular transport, mobility, and particularly mitosis. Paclitaxel (Taxol$^{TM}$) and paclitaxel-like compounds have been shown to be anti-tumor agents useful for various human tumors. Paclitaxel-like compounds operate by stabilizing microtubules through interface binding at the interface between two ${\beta}$-tubulin monomers in adjacent protofilaments. In this paper we present the elucidation of the structural features of paclitaxel and paclitaxel-like compounds (e.g., epothilones) with microtubule stabilizing activities, and relate their activities to spatial and chemical features of the molecules. CATALYST program was used to generate three-dimensional quantitative structure activity relationships (3D-QSARs) resulting in 3D pharmacophore models of epothilone- and paclitaxel-derivatives. Pharmacophore models were generated from diverse conformers of these compounds resulting in a high correlation between experimental and predicted biological activities (r = 0.83 and 0.91 for epothilone and paclitaxel derivatives, respectively). On the basis of biological activities of the training sets, five- and four-feature pharmacophore hypotheses were generated in the epothilone and paclitaxel series. The validation of generated hypotheses was achieved by using twelve epothilones and ten paclitaxels, respectively, which are not in the training sets. The clustering (grouping) and merging techniques were used in order to supplement spatial restrictions of each of hypothesis and to develop more comprehensive models. This approach may be of use in developing novel inhibitor candidates as well as contributing a better understanding of structural characters of many compounds useful as anticancer agents targeting microtubules.

• JSTS:Journal of Semiconductor Technology and Science
• /
• v.14 no.5
• /
• pp.508-517
• /
• 2014

We design and analyze the n-channel junctionless fin-shaped field-effect transistor (JL FinFET) with 10-nm gate length and compare its performances with those of the conventional bulk-type fin-shaped FET (conventional bulk FinFET). A three-dimensional (3-D) device simulations were performed to optimize the device design parameters including the width ($W_{fin}$) and height ($H_{fin}$) of the fin as well as the channel doping concentration ($N_{ch}$). Based on the design optimization, the two devices were compared in terms of direct-current (DC) and radio-frequency (RF) characteristics. The results reveal that the JL FinFET has better subthreshold swing, and more effectively suppresses short-channel effects (SCEs) than the conventional bulk FinFET.