• Korean Journal of Veterinary Research
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• v.58 no.4
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• pp.211-217
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• 2018

Mesenchymal stem cells (MSCs) are useful candidates for tissue engineering and cell therapy. Physiological cell environment not only connects cells to each other, but also connects cells to the extracellular matrix that provide mechanical support, thus exposing the entire cell surface and activating signaling pathways. Hydrogel is a polymeric material that swells in water and maintains a distinct 3-dimensional (3D) network structure by cross linking. In this study, we investigated the optimized cellular function for canine adipose tissue-derived MSCs (cAD-MSCs) using hydrogel. We observed that the expression levels of Ki67 and proliferating cell nuclear antigen, which are involved in cell proliferation and stemness, were increased in transwell-hydrogel (3D-TN) compared to the transwell-normal (TN). Also, transforming growth factor-${\beta}1$ and SOX9, which are typical bone morphogenesis-inducing factors, were increased in 3D-TN compared to the TN. Collagen type II alpha 1, which is a chondrocyte-specific marker, was increased in 3D-TN compared to the TN. Osteocalcin, which is a osteocyte-specific marker, was increased in 3D-TN compared to the TN. Collectively, preconditioning cAD-MSCs via 3D culture systems can enhance inherent secretory properties that may improve the potency and efficacy of MSCs-based therapies for bone regeneration process.

• Journal of the Korean Society of Radiology
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• v.12 no.7
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• pp.879-886
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• 2018

A 3-dimensional (D) printer is a device capable of outputting a three-dimensional solid object based on data modeled in a computer. These features are utilized in the bone model X - ray phantom production etc using CT data by fusing with the radiation science field. A bone model phantom was made using data obtained by CT scan of an existing Pelvis phantom, using PLA, Wood, XT-CF20, Glow fill, Steel filaments which are materials of Fused Filament Fabrication (FFF) 3D printer.Measure Hounsfield Unit (HU) with images obtained by CT scan of the existing Pelvis phantom and five material phantoms made with 3D printer under the same conditions,SI and SNR were measured using a diagnostic X-ray generator, and each phantom was compared and analyzed.As a result, the X - ray phantom in the X - ray examination condition of the limb was found to be most suitable for the glow fill filament.The characteristics of the filament can be known to the base of this research and the practicality of X - ray phantom fabrication was confirmed.

• Journal of radiological science and technology
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• v.40 no.1
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• pp.87-92
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• 2017

The weight of small animal dosimetry has been continuously increased in pre-clinical studies using radiation in small animals. In this study, three-dimensional(3D) small animal phantom was fabricated using 3D printer which has been continuously used and studied in the various fields. The absorbed dose of 3D animal phantom was evaluated by film dosimetry. Previously, the response of film was obtained from the materials used for production of 3D small animal phantom and compared with the bolus used as the tissue equivalent material in the radiotherapy. When irradiated with gamma rays from 0.5 Gy to 6 Gy, it was confirmed that there was a small difference of less than 1% except 0.5 Gy dose. And when small animal phantom was irradiated with 5 Gy, the difference between the irradiated dose and calculated dose from film was within 2%. Based on this study, it would be possible to increase the reliability of dose in pre-clinical studies using irradiation in small animals by evaluating dose of 3D small animal phantom.

• Journal of the Korea Institute of Information and Communication Engineering
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• v.14 no.9
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• pp.1987-1992
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• 2010

This paper deals with the method of using the three dimensional characteristic information to classify the front environment in travelling by using the images captured by a CCD camera equipped on a mobile robot. The images detected by the three dimensional characteristic information is divided into the part of obstacles, the part of corners, and th part of doorways in a corridor. In designing the travelling path of a mobile robot, these three situations are used as an important information in the obstacle avoidance and optimal path computing. So, this paper proposes the method of deciding the travelling direction of a mobile robot with using input images based upon the suggested algorithm by preprocessing, and verified the validity of the image information which are detected as obstacles by the analysis through neural network.

• Journal of the Korean Society of Manufacturing Process Engineers
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• v.19 no.9
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• pp.59-70
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• 2020

Three-dimensional (3D) design data is used for various purposes throughout the life cycle of a plant construction project. Plant 3D CAD systems support 3D modeling based on specs-catalogs, which contain data that are used for different purposes such as design, procurement, production, and handover. Therefore, it is important to share the spec-catalog data in the 3D design model with other application systems. Sharing this data thus requires a system that extracts spec-catalog data from plant 3D CAD systems and converts them into neutral model data. In this paper, we analyze equipment spec-catalog data of plant 3D CAD systems and, based on these analyses, define the data structure for neutral spec-catalog data. We subsequently propose a procedure that translates native spec-catalog data to neutral model data and develop a prototype system that performs this operation. The proposed method is then experimentally validated for the test spec-catalog data.

• Archives of Plastic Surgery
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• v.43 no.1
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• pp.32-37
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• 2016

Background We conducted this study to analyze the values of the key cephalometric angular measurements of the mandible using 3-dimensional (3D) computed tomography scans. Methods In the 106 enrolled patients, a 3D cephalometric analysis was performed to measure the angular variables of the mandible. These values were compared between the two sides and between the two sexes. Results The frontal measurements revealed that the mandibular body curve angle was larger on the left (Lt) side (right [Rt], $141.24{\pm}7.54$; Lt, $142.68{\pm}6.94$; P=0.002) and the gonial angle was larger on the right side (Rt, $134.37{\pm}8.44$; Lt, $131.54{\pm}7.14$; P<0.001). The sagittal measurements showed that the gonial angle was larger on the right side (Rt, $134.37{\pm}8.44$; Lt, $131.54{\pm}7.14$; P>0.05). Further, the transverse measurements revealed that the mandibular body curve angle was larger on the right side (Rt, $140.28{\pm}7.05$; Lt, $137.56{\pm}6.23$; P<0.001). Conclusions These results provide an average of the mandibular angular measurements for the Korean population, establishing a standard for determining surgical patient groups and outcome evaluations in the field of mandible contour surgery.

• Journal of Korean Tunnelling and Underground Space Association
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• v.10 no.2
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• pp.139-152
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• 2008

A series of numerical experiments were carried out to simulate the rock cutting behavior by TBM disc cutter in a given took condition. AUTODYN-3D, a commercial program capable of simulating three-dimensional dynamic failure, was utilized to carry out the numerical tests over four different disc cutter spacing conditions. After modelling three-dimensional geometries of disc cutter and rock specimen, the linear cutting tests by a disc cutter were simulated for eight different types of rocks. The numerical result, that is the optimum cutter spacing for isotropic rocks had the good agreements with those from linear cutting test. However, for relatively anisotropic or jointed rocks, the specific energy obtained from the numerical tests was almost two-times bigger than the real linear cutting results. Therefore, to simulate cutting procedures for anisotropic rocks realistically, further studies would be necessary.

• Progress in Medical Physics
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• v.11 no.1
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• pp.85-90
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• 2000

In radiation therapy, the effects of radiation are decided total dose, total treatment times and number of radiation dose fractions. We considered that total dose, total treatment times and number of radiation dose fractions in intensity modulation radiation therapy(IMRT) infuence tumor cell killing. The goal of three dimensional conformal radiation therapy(3DCRT) in radiation therapy is to conform the partial distribution of the prescribed radiation dose to the precise 3D configuration of the tumor, and at the same time, to minimize the dose to the surrounding normal tissues. To optimize treatment volume of tumor, treatment volume will be same tumor volume. All IMRT compare to conventional treatment plus boost IMRT when total dose irradiated 75 - 90 Gy. Because of biological effect, total dose are decreased 12.5 - l5Gy in all IMRT.

• Journal of Korea Multimedia Society
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• v.13 no.7
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• pp.1095-1104
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• 2010

This study is to suggest the design generation methodology for the maximization of idea generation ability and to overcome restriction of thinking out of existing idea generation methodology, it has suggested the CGS(Character Generation System) that is a creative idea generation methodology identified and complemented the problem of the existing computerized idea generation(PDS with Proportion) method out of the preceded studies on the creative idea generation methodologies. In addition, this research being extended on the article vol.11,no.11, "CGS System based on Three-Dimensional Character Modeling Ⅰ(Part1: about Non-Digital Process )," on Korea Multimedia Society in November 2008 issue and this study is expected to have effectives as one method for idea generation or creative image generation assistance during the 3D character development process with practical implementation of system, research directions and present the results.

• Journal of Electrochemical Science and Technology
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• v.9 no.3
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• pp.229-237
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• 2018

The electrochemical sensing performance of metal-graphene hybrid based sensor may be significantly decreased due to the dissolution and aggregation of metal catalyst during operation. For the first time, we developed a novel large-area high quality three dimensional graphene foam-incorporated gold nanoparticles (3D-GF@Au) via chemical vapor deposition method and employed as free-standing electrocatalysis for non-enzymatic electrochemical glucose detection. 3D-GF@Au based sensor is capable to detect glucose with a wide linear detection range of $2.5{\mu}M$ to 11.6 mM, remarkable low detection limit of $1{\mu}M$, high selectivity, and good stability. This was resulted from enhanced electrochemical active sites and charge transfer possibility due to the stable and uniform distribution of Au NPs along with the enhanced interactions between Au and GF. The obtained results indicated that 3D-GF@Au hybrid can be expected as a high quality candidate for non-enzymatic glucose sensor application.