• Title/Summary/Keyword: 3-MX

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THE RELATIONS BETWEEN CRANIOFACIAL MORPHOLOGY AND DENIAL AESTHETIC INDEX(DAI) (치열심미지수(DAI)와 악안면 형태와의 관계)

  • Choi, Yong-Sung;Kim, Eun-Kyung;Choi, Hyun-Gue;Kim, Jong-Ghee
    • The korean journal of orthodontics
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    • v.27 no.6 s.65
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    • pp.871-880
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    • 1997
  • Multiple features of occlusion have been combined by epidemiologists in attempts to objectively to determine malocclusion severity and treatment priority. Jenny et al were developed DAI(Dental Aesthetic Index), which is an orthodontic index based on socially defined aesthetic standards. This study aimed to evaluate association between 10 occlusal components of DAI and individual measures of skeletal morphology by use of univariate and multivariate analysis. In addition the relationship between a Dental Aesthetic Index score and skeletal morphology was evaluated. The data for this study were obtained from cephalometric radiographs and dental casts of 182 Korean patients(79 men, 103 women) with permanent dentition who had been accepted for the orthodontic treatment at Department of Orthodontics, Chonbuk National University. The results are as follows: 1. Several occlusal components of DAI(missing, crowding and spacing in the incisal segment, diastema, largest anterior irregularity on upper and lower arch) were not associated with individual measures of craniofacial morphology. 2. Sagittal occlusal components of DAI were associated with anteroposterior skeletal measures. 3. The relation between vertical occlusal components of DAI and vertical skeletal measures was low magnitude. 4. A Dental Aesthetic Index, which is based on several aspects of occlusion, did not identify craniofacial morphology. We can conclude that combination of certain occlusal components of the DAI may be related with specific skeletal morphology; but, this concept could not be accepted generally.

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Generation and Characterization of Monoclonal Antibodies against Human Interferon-lambda1

  • Hong, Seung-Ho;Kim, Jung-Sik;Park, Sun
    • IMMUNE NETWORK
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    • v.8 no.1
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    • pp.7-12
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    • 2008
  • Background: Members belonging to the interferon-lambda (IFN-${\lambda}$) family exert protective action against viral infection; however, the mechanisms of their action have remained elusive. To study IFN-${\lambda}$ biology, such as endocytosis of IFN-${\lambda}$, we produced monoclonal antibodies (Abs) against human IFN-${\lambda}$ and examined their usefulness. Methods: We purified recombinant human IFN-${\lambda}$1 expressed in Escherichia coli by using affinity columns. Then, we generated hybridoma cells by fusing myeloma cells with splenocytes from IFN-${\lambda}$1-immunized mice. For evaluating the neutralizing activity of the monoclonal Abs against IFN-${\lambda}$1, we performed RT-PCR for the MxA transcript. In order to study the binding activity of IFN-${\lambda}$ and the monoclonal Ab complex on HepG2 cells, we labeled the monoclonal Ab with rhodamine and determined the fluorescence intensity. Results: Four hybridoma clones secreting Abs specific to IFN-${\lambda}$1 were generated and designated as HL1, HL2, HL3, and HL4. All the Abs reacted with IFN-${\lambda}$1 in the denatured form as well as in the native form. Abs produced by HL1, HL3, and HL4 did not neutralize the induction of the MxA gene by IFN-${\lambda}$1. We also demonstrated the binding of the HL1 monoclonal anbitody and IFN-${\lambda}$ complex on HepG2 cells. Conclusion: Monoclonal Abs against IFN-${\lambda}$1 were produced. These Abs can be used to study the cellular binding and internalization of IFN-${\lambda}$.

Change in three dry rangeland species growth and soil properties by compost application

  • Sadeghi, Hossein;Shourije, Fatemeh Ansar;Masoudi, Masoud
    • Journal of Ecology and Environment
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    • v.35 no.2
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    • pp.131-140
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    • 2012
  • There are different types of compost used as soil conditioners and fertilizers. Plants can have different responses to different forms of compost. This field study was performed to examine the effects of different types of compost on growth factors of three dry rangeland species (Atriplex, $Atriplex$ $lentiformis$; Saltwort, $Seidlitzia$ $rosmarinus$; Haloxylon, $Haloxylon$ $persicum$) and soil properties. The experiment was conducted in the Fars Province of Iran during the year 2010-2011. Compost applications consisted of compost tea, solid compost (SC), solid and liquid mixture (MX) and no compost as the control. The study was a factorial experiment based on a randomized complete block design with 3 replications. The results showed that all the tested compost applications enhanced the growth traits of all three species. It was also demonstrated that the use of compost significantly increased the organic matter (1% probability level [PL]), nitrogen concentration (5% PL), phosphorous (5% PL) and potassium (5% PL) concentrations of the soil. The soil's pH level was unchanged (range, 7.3 to 7.6), and the sodium concentration was also significantly decreased (1% PL) by the use of compost. The higher responses were observed in canopy volume and soil sodium and the lower were observed in stem diameter and soil pH level. Among the three plants in the study, Atriplex showed the best response to the application of compost. Based on the results of this study, it can be recommended that the best compost application to increase growth and improve soil condition is the mixed compost (MX) for Atriplex and the SC for Saltwort and Haloxylon.

Rapid Determination of Electroplating Solutions (1) -Copper from Copper Plating Solutions (각종 도금액의 신속분석법 (제 1 보))

  • 염희택
    • Journal of the Korean institute of surface engineering
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    • v.1 no.1
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    • pp.5-13
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    • 1967
  • Up to this date, numerous methods of analysis of electropling solutions are published. Some, however, need lots of works before reaching final results, or require high technique and special instruments, and also some are unaccurate due to unclearnes of end point. Like our undevelop countries, technicians of electroplating shops are most high school graduates or under, and have not much knowledge on chemistry. Furthermore, those technicians have to control their plating solutions by themselves without having enough analytical laboratory equipment . Therefore, in this paper the simplest, besides accurate method is investigated after comparing numerous methods published. Among the methods of copper determinations from acid and alkaline copper plating baths, EDTA titration method are chosen, due to these methods are the simpest and fastest for the evaluation of metal content, without requirng any special instrument. For acid copper solutions, chelate titrations were accurate enough. Since the end point of titration of chelate method is variable according to the kind of indicators and other metal's coexisitence as well as solution component, many difficulties were encountered from cyanide copper, on the contrary of acid copper bath. PAN , PV, and MX indicators were tried , but it is found that MX is the best. In chyanide solution ,due to cyanide is the masking reagent , elimination of this component is essential , and finally found that elimination CN-by precipitation with AgNO$_3$ solution was the simplest and the most accurate way among others. This method was very accurate for the new plating solutions even coexistence with organic brightners. However used solutions for long months running have to be predetermined the accurate copper value by thiosulfate method form time to time, before chelate titration by means of AgNO$_3$ precipitation. Always some constant deviations will be seen according to the solutions nature. Therefore those deviation values have to be compensated each time.

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Comparative Molecular Field Analysis (CoMFA) and Comparative Molecular Similarity Index Analysis (CoMSIA) Study of Mutagen X

  • Bang, Soo-Jin;Cho, Seung-Joo
    • Bulletin of the Korean Chemical Society
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    • v.25 no.10
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    • pp.1525-1530
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    • 2004
  • Mutagen X (MX) exists in our drinking water as the bi-products of chlorine disinfection. Being one of the most potent mutagen, it attracted much attention from many researchers. MX and its analogs are synthesized and modeled by quantitative structure activity relationship (QSAR) methods. As a result, factors affecting this class of compounds have been found to be steric and electrostatic effects. We tried to collect all the data available from the literature. With both CoMFA and CoMSIA various combinations of physiochemical parameters were systematically studied to produce reasonable 3-dimensional models. The best model for CoMFA gave $q^2$ = 0.90 and $r^2$ = 0.97, while for CoMSIA $q^2$ = 0.85 and $r^2$ = 0.94. So the models seem to be reasonable. Unlike previous result of CoMFA, in our case steric parameter alone gave the best statistics. Although the steric contribution was found to be the most important in both CoMFA and CoMSIA, steric parameter along with electrostatic parameter produced slightly better model in CoMSIA. Overall, steric contribution is clearly the most important single factor. However, when we compare chlorine and bromine substitution, chlorine substitution can be more mutagenic. This indicates that other factors such as electrostatic effect also influence the mutagenicity. From the contour maps, steric contribution seems to be focused on rather small area near C6 substituent of the furanone ring, rather than C3 substituent. Therefore the locality of steric contribution can play a significant role in mutagenicity.

Fabrication and Characterization of Hexagonal Tungsten Oxide Nanopowders for High Performance Gas Sensing Application (육방정계 텅스텐옥사이드 나노분말의 합성과 고성능 가스센서응용을 위한 성능 평가)

  • Park, Jinsoo
    • Journal of Powder Materials
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    • v.26 no.1
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    • pp.28-33
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    • 2019
  • The gas sensor is essential to monitoring dangerous gases in our environment. Metal oxide (MO) gas sensors are primarily utilized for flammable, toxic and organic gases and $O_3$ because of their high sensitivity, high response and high stability. Tungsten oxides ($WO_3$) have versatile applications, particularly for gas sensor applications because of the wide bandgap and stability of $WO_3$. Nanosize $WO_3$ are synthesized using the hydrothermal method. As-prepared $WO_3$ nanopowders are in the form of nanorods and nanorulers. The crystal structure is hexagonal tungsten bronze ($MxWO_3$, x =< 0.33), characterized as a tunnel structure that accommodates alkali ions and the phase stabilizer. A gas detection test reveals that $WO_3$ can detect acetone, butanol, ethanol, and gasoline. This is the first study to report this capability of $WO_3$.

A STUDY ON THE CORRELATIONSHIP OF SUBMENTOVERTEX VIEW AND LATERAL CEPHALOGRAM MEASUREMENTS (이하두정방사선사진과 측모두부방사선사진상에서의 계측치 상호연관성에 관한연구)

  • Cho, Jae-Hyung;Ryu, Young-Kyu
    • The korean journal of orthodontics
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    • v.26 no.4
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    • pp.414-420
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    • 1996
  • Cephalometric measureements have disadvantage of representing cranio-facial structures in two dimension only and therefore they pose limitations in describing three-dimentional structures of cranio-facial region. More interests have been put on the correlation between the two planes. This study evaluated correlations between facial type score, which allows effects on malocclusion, growth change prediction and establishment of treatment method and prognosis, and measurements from submentovertex view. Cephalometric view and submentovertex view were taken of skeletal Class I adults with optimal profile and correlations between them have been observed. Following results were obtained: 1. To learn about factors that influence average condylar angulation, FACE, INT-CO-ANG, MN-CORPUS, CON-RATIO, GON-RATIO, MN-RATIO were used as variables and underwent multiple regression analysis. As a result, the following equation was obtained : CON-AVE=.l73(FACE)-.322(INT-CO-ANG)+36.34(GON-RATIO) +.420(MN-CORPUS) (($R^2=.85451$) 2. The following equation was obtained concerning facial type score. FACE= .050(CON-ANG)+.023(INT-CO-ANG)-.075(MN-CORPUS)($R^2=.31547$) 3. Among the submentovertex measurements, MN-CORPUS, CON-RATIO, GON-RATIO, MN-RATIO showed close correlations. (P<0.05) 4. Average condylar angualtions were $23.37^{\circ}$ on the right and $20.71^{\circ}$ on left. There was a difference between the two. FACE : facial type soore. CON-ANG: mean value of condylar angulation. CON-AVE: mean value of Rt. Lt condylar angulation. INT-CO-ANG : angle between Rt. Lt condylar axis. MN-CORPUS : angle formed between RT. Lt gonion & pogonion. CON-RATIO: lntercondylar distance/mandibular body length. GON-RATIO : intergonion distanoe/mandibular body length. MN-RATIO: lntermylohyoid distance/mandibular body length. MX-RATIO: intermaxillary tuberosity distance/ANS-PNS distance.

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THE LATERAL CEPHALOMETRIC STUDY OF THE GROWING CHILDREN WITH CLASS III MALOCCLUSION BY MCNAMARA ANALYSIS (McNamara분석법에 의한 III급 부정교합 아동의 두부방사선 계측학적 연구)

  • Yang, Ku-Ho;Kim, Ji-Young;Choi, Nam-Ki
    • Journal of the korean academy of Pediatric Dentistry
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    • v.28 no.3
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    • pp.412-420
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    • 2001
  • In the growing children with normal occlusion and class III malocclusion who need the early treatment to be helped to diagnose and to set up treatment plan by calculating the mean values of the lateral cephalometric measurements, cephalometric measurements by McNamara alalysis were achieved and compared on both the 84 elementary school children with normal occlusion and 83 class III malocclusion children at the age of 7 to 9 in Kwangju city and the results were as follows: 1. On the boys group, between normal occlusion and class III malocclusion, Effective maxillary length, Maxillomandibular differential, Facial axis, Nasion perpendicualr to pogonion, Point A perp to Mx 1, and A-Pog line to Mn 1 showed significant differences(p<0.05). 2. On the girls group, between normal occlusion and class III malocclusion significant differences were shown in Effective Maxillary length, Maxillomandibular differential, Mandibular plan angle, Nasion perpendicualr to Point A, Point A perp to Mx 1, A-Pog line to Mn 1(p<0.01). 3. There were no significant differences between normal occlusion and class III malocclusion of boys group but significant differences between them of girls group in Effective mandibular length(P<0.01). On the boys and girls group, Effective maxilla length of class III malocclusion was shorter than that of normal occlusion. 4. There were no significant differences between normal occlusion and class III malocclusion both in boys and girls at Anterior lower facial height. 5. There were significant differences between boys and girls both in class III malocclusion and normal occlusion at Anterior lower facial height and Mandibular plane angle(p<0.01).

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Microstructural Development of Ferritic 11Cr-3.45W Heat-resistance Steel for Ultra-supercritical Power Plant During Creep and Thermal Aging (크리프와 등온열화에 따른 초초임계압 발전설비용 페라이트계 11Cr-3.45W 내열합금강의 미세조직 변화)

  • Kim, Chung-Seok
    • Journal of the Korean Society for Heat Treatment
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    • v.31 no.3
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    • pp.91-96
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    • 2018
  • Microstructural development of ferritic 11Cr-3.45W heat-resistance steel for ultra-supercritical power plant during creep and thermal aging was investigated using electron microscopy. The test samples were isothermally aged at $700^{\circ}C$ for up to 4000 hours and subjected to creep loading at $700^{\circ}C$ for predetermined periods of lifetime to prepare the damaged materials. In this structural material, a various secondary phases are the primary influence on mechanical properties of ferritic heat-resistance steel. The typical precipitates of $M_{23}C_6$, MX and $M_2X$ secondary phases had been analyzed through qualitative and quantitative manner. Coarsening of precipitates and increase of lath width were observed during creep and thermal aging. This phenomenon was remarkable for creep process compared with isothermal aging process.

The Biomechanical Evaluation of New Walking-shoes (신 워킹 전문화의 생체역학적 기능성 평가)

  • Kim, Eui-Hwan;Chung, Chae-Wook;Lim, Jung
    • Korean Journal of Applied Biomechanics
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    • v.16 no.2
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    • pp.193-205
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    • 2006
  • This study was to analysis the kinematic and kinetic differences between new walking shoe(NWS : RYN) and general walking shoe(GWS). The subjects for this study were 10 male adults who had the walking pattern of rearfoot shrike with normal foot. The movement of one lower leg was measured using plantar pressure and Vicon Motion Analysis Program(6 MX13 and 2 MX40 cameras : 100 f / s) while the subjects walked at the velocity(1.5m/s. on 2m).. The results of this study was as follows : 1. The NWS was better than the GWS that caused injuries such as adduction, abduction and pronation are reduced While walking on a perpendicular surface, the landing angle and the knees angles were extensive which makes walking more safe which reduces anxiety and uneasiness. 2. The bottom of the NWS were now made into a more circular arch which supports the weight of the body and reduces the irregular angles when wearing GWS. This arch made the supporting area more wide which made the upholding the trunk of the body more effective. The whole bottom of the foot that supports the weight is more flexible in addition, increases the safeness of walking patterns and the momentum of the body. 3. The moment the heel of the foot of the NWS touch the ground, the range of the pressure were partially notable and the range of the pressure on the upper part of the thigh were dispersed The injuries that occurred while walking. primary factors when a shock related injuries are reduced Judgements of the impacts of the knees and the spinal column dispersing could be made.