• Title/Summary/Keyword: 3-Chloro-4-fluoropropiophenone

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Optimization of Reduction of 3-chloro-4-fluoropropiophenone by Whole Cells of Saccharomyces cerevisiae (Saccharomyces cerevisiae를 이용한 3-chloro-4-fluoropropiophenone 환원 반응 최적화)

  • Lee, Hae-Ryong;Jeong, Min;Yoo, Ik-Keun;Hong, Soon-Ho
    • KSBB Journal
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    • v.26 no.6
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    • pp.569-571
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    • 2011
  • Reduction of 3-chloro-4-fluoropropiophenone by Saccharomyces cerevisiae as a whole cell biocatalyst was optimized. Effects of glucose, S. cerevisiae and 3-chloro-4-fluoropropiophenone concentrations on conversion of reduction reaction was investigated. Optimum concentrations of glucose, S. cerevisiae and 3-chloro-4-fluoropropiophenone were 100, 40 and 20 g/L, respectively. At optimum condition, 100% of conversion was achieved in 12 hours of reaction.