• Journal of Yeungnam Medical Science
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• 제21권1호
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• pp.40-50
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• 2004

특발성 척추측만증 환자에서 3차원적인 재구성을 이용한 관상면에서 척추경의 폭을 측정하는 것이 오차를 줄일 수 있는 방법이고 척추경 나사못의 삽입 시 척추경의 크기를 술 전에 측정한 후 그 값의 최대치보다 작은 최대 크기의 원추형 나사못을 삽입하는 것이 안전한 방법이라 사료된다. 척추경 나사못을 삽입할 시에는 척추경의 모양이 원주 형태가 아닌 낙루 형태나 신장 형태 등 추체마다의 다양한 모양을 고려하여 나사못 크기와 삽입 방법에 세심한 주의가 필요할 것으로 사료된다.

• 전자공학회논문지
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• 제53권9호
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• pp.137-142
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• 2016

컴퓨터단층촬영(CT) 검사의 정맥주사(IV)시 조영제의 혈관외유출은 조직손상을 유발할 수 있다. Bolus tracking 시스템을 이용하여 조영제를 주입과정에서 발생하는 혈관외유출을 검출한다. 또한 조직손상을 방지하기 위하여 MPR 및 VR 영상을 이용하여 혈관외유출을 검출하였다. 조영제의 혈관외유출을 검출하기 위하여 16MDCT, 64MDCT를 사용하였다. 혈관외유출에 대한 3차원영상은 환자치료에 중요한 치료정보를 제공할 수 있다. 또한 조영제와 조직 간의 선예도를 개선하기 위해서 edge enhancement 영상처리기법을 적용하였고, 선예도 및 대조도가 개선되었다.

• Journal of Korean Neurosurgical Society
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• 제47권3호
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• pp.180-184
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• 2010

Objective : To prevent temporal depression after the pterional craniotomy, this study was designed to examine the safety and aesthetic efficacy of the brushite calcium phosphate cement (CPC) in the repair and augmentation of bone defects following the pterional craniotomy. Methods : The brushite CPC was used for the repair of surgically induced cranial defects, with or without augmentation, in 17 cases of pterional approach between March, 2005 and December, 2006. The average follow-up month was 20 with range of 12-36 months. In the first 5 cases, bone defects were repaired with only brushite CPC following the contour of the original bone. In the next 12 cases, bone defects were augmented with the brushite CPC rather than original bone contour. For a stability monitoring of the implanted brushite CPC, post-implantation evaluations including serial X-ray, repeated physical examination for aesthetic efficacy, and three-dimensional computed tomography (3D-CT) were taken 1 year after the implantation. Results : The brushite CPC paste provided precise and easy contouring in restoration of the bony defect site. No adverse effects such as infection or inflammation were noticed during the follow-up periods from all patients. 3D-CT was taken 1 year subsequent to implantation showed good preservation of the brushite CPC restoration material. In the cases of the augmentation group, aesthetic outcomes were superior compared to the simple repair group. Conclusion : The results of this clinical study indicate that the brushite CPC is a biocompatible alloplastic material, which is useful for prevention of temporal depression after pterional craniotomy. Additional study is required to determine the long-term stability and effectiveness of the brushite calcium phosphate cement for the replacement of bone.

• Radiation Oncology Journal
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• 제24권2호
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• pp.81-87
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• 2006

목적: 3차원 입체조형 방사선치료를 시행 받은 코인두암 환자에서 설문조사를 이용하여 구강건조증의 시간경과에 따른 변화양상을 분석하고자 하였다. 대상 및 방법: 2000년 12월부터 2005년 8월까지 코인두암 환자에서 3차원 입체조형 방사선치료를 적용한 환자 51명을 설문조사의 대상으로 하였다. 3차원 입체조형 방사선치료는 3회의 컴퓨터 단층촬영(Computed tomography: CT)모의치료를 이용한 3단계 치료계획을 시행하는 순차적 조사영역 축소방법을 사용하였고, 총 선량 72 Gy를 목표로 하였다. 구강건조증은 일상생활에서 중요한 4가지 항목으로 구성된 설문점수(xerostomia questionnaire score: XQS)를 측정하였으며, 방사선치료 후 경과시간, 성별, 나이, 병기, 항암치료의 병용유무, 그리고 이하선의 평균 방사선량 등에 따르는 차이를 분석하였다. 결과: 항암치료를 병용한 환자가 40명, 방사선치료 단독환자가 11명이었으며, 방사선치료 후 설문조사까지 경과 시간은 중앙값 20 ($1{\sim}58$)개월이었다. 전체 환자에서 XQS 점수의 평균은 8.4점(최하 6점, 최고 14점, 표준편차 1.9)이었다. 방사선치료 후 경과시간에 따라 XQS 점수는 통계적으로 유의하게 감소하는 경향을 보였다($X^2$=-0.484, p<0.05). 성별, 나이, 병기에 따라 XQS 점수의 차이는 없었고, 항암치료를 병용한 환자에서 방사선치료 단돈 환자와 비교하여 XQS 점수가 유의하게 높았다(p=0.001). 전체 이하선의 평균선량은 35 Gy 미만에서 35 Gy 이상보다 XQS 점수가 통계적으로 유의하게 낮았다(p=0.05). 결론: 코인두암 환자에서 3차원 입체조형 방사선치료 후 측정한 XQS 점수는 방사선치료 후 시간경과에 따라 감소하는 양상을 보였으며, 항암치료를 병용함으로써 더 악화되는 경향이 있고, 이하선에 조사되는 평균선량을 35Gy 미만으로 하는 것이 구강건조증 증상완화에 도움이 될 수 있겠다.

• Archives of Plastic Surgery
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• 제35권1호
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• pp.28-35
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• 2008

Purpose: The pedicle of transverse rectus abdominis myocutaneous(TRAM) flap and deep inferior epigastric arterial perforator flap is deep inferior epigastic artery (DIEA) and accurate anatomic knowledge about perforator of DIEA is very important for the elevation of these flap. The authors investigated a detailed vascular network of perforator of DIEA in Koreans. Methods: 24 fresh cadavers were studied. Among them, 15 were examined based on the plain X-ray examination for the distribution and location of perforator of DIEA. And 9 fresh cadavers were examined based on the 3-dimensional computed tomography(CT) study for the distance between ending point of perforator of DIEA and mother artery, the distance between most medial mother artery and midline, the distance between most lateral mother artery and midline, and the running type of perforators of DIEA. Results: Based on the plain X-ray examination, suitable(external diameter$${\geq_-}0.5mm$$) perforators of DIEA are located between the level of umbilicus and 8 cm below it. Based on the 3D-CT study, average distance between the ending point of perforator of DIEA and the mother artery is 30.26 mm on the left, 28.62 mm on the right, respectively. The average distance between most medial mother artery and midline is 17.13 mm on the left, 15.76 mm on the right, respectively. The average distance between most lateral mother artery and midline is 56.31 mm on the left, 50.90 mm on the right, respectively. The main running course of suitable perforators of DIEA is type a, which is a direct musculocutaneous perforator vessel from main vascular axis passing outward to join the subdermal plexus, directly. Conclusion: 3-dimensional computed tomography study as well as plain X-ray examination provided more accurate and detail informations about perforators of DIEA in Koreans. These informations will help us understand the detailed vascular anatomy and operation with ease and safe in the lower abdomen of Koreans.

• 한국의학물리학회지:의학물리
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• 제28권4호
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• pp.144-148
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• 2017

When a high density metallic implant is placed in the path of the proton beam, spatial heterogeneity can be caused due to artifacts in three dimensional (3D) computed tomography (CT) scans. These artifacts result in range uncertainty in dose calculation in treatment planning system (TPS). And this uncertainty may cause significant underdosing to the target volume or overdosing to normal tissue beyond the target. In clinical cases, metal implants must be placed in the beam path in order to preserve organ at risk (OARs) and increase target coverage for tumors. So we should introduce Ti-mesh. In this paper, we measured the lateral dose profile for proton beam using an EBT3 film to confirm dosimetric impact of Ti-mesh when the Ti-mesh plate was placed in the proton beam pathway. The effect of Ti-mesh on the proton beam was investigated by comparing the lateral dose profile calculated from TPS with the film-measured value under the same conditions.

• 대한두개안면성형외과학회지
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• 제17권3호
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• pp.162-164
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• 2016

Stafne bone cavity is a rare mandibular defect that was first reported by Edward C. Stafne in 1942. It commonly presents with a well-demarcated, asymptomatic, unilateral radiolucency that indicates lingual invagination of the cortical bone. A 52-year-old female patient who with nasal bone fracture, visited the hospital. During facial bone computed tomography (CT) for facial area evaluation, a well-shaped cystic lesion was accidentally detected on the right side of the mandible. Compared to the left side, no swelling or deformity was observed in the right side of the oral lesion, and no signs of deformity caused by mucosal inflammation. 3D CT scans, and mandible series x-rays were performed, which showed a well-ossified radiolucent oval lesion. Axial CT image revealed a cortical defect containing soft tissue lesion, which has similar density as the submandibular gland on the lingual surface of the mandible. The fact that Stafne cavity is completely surrounded by the bone is the evidence to support the hypothesis that embryonic salivary gland is entrapped by the bone. In most cases, Stafne bone cavity does not require surgical treatment. We believe that the mechanical pressure from the salivary gland could have caused the defect.

• 방송공학회논문지
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• 제28권3호
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• pp.293-301
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• 2023

표준화되지 않은 의료 데이터 수집 및 관리는 여전히 수동으로 진행되고 있어, 이 문제를 해결하기 위해 딥 러닝을 사용해 CT 데이터를 분류하는 연구들이 진행되고 있다. 하지만 대부분 연구에서는 기본적인 CT slice인 axial 평면만을 기반으로 모델을 개발하고 있다. CT 영상은 일반 이미지와 다르게 인체 구조만 묘사하기 때문에 CT scan을 재구성하는 것만으로도 더 풍부한 신체적 특징을 나타낼 수 있다. 이 연구는 axial 평면뿐만 아니라 CT 데이터를 2D로 변환하는 여러가지 방법들을 통해 보다 높은 성능을 달성할 수 있는 방법을 찾고자 한다. 훈련은 5가지 부위의 CT 스캔 1042개를 사용했고, 모델 평가를 위해 테스트셋 179개, 외부 데이터셋으로 448개를 수집했다. 딥러닝 모델 개발을 위해 ImageNet으로 사전 학습된 InceptionResNetV2를 백본으로 사용하였으며, 모델의 전체 레이어를 재 학습했다. 실험결과 신체 부위 분류에서는 재구성 데이터 모델이 99.33%를 달성하며 axial 모델보다 1.12% 더 높았고, 조영제 분류에서는 brain과 neck에서만 axial모델이 높았다. 결론적으로 axial slice로만 훈련했을 때 보다 해부학적 특징이 잘 나타나는 데이터로 학습했을 때 더 정확한 성능 달성이 가능했다.

• 한국의학물리학회지:의학물리
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• 제32권2호
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• pp.40-49
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• 2021

Purpose: This study aimed to develop a surface-guided radiosurgery system customized for a neurosurgery clinic that could be used as an auxiliary system for improving the accuracy, monitoring the movements of patients while performing hypofractionated radiosurgery, and minimizing the geometric misses. Methods: RGB-D cameras were installed in the treatment room and a monitoring system was constructed to perform a three-dimensional (3D) scan of the body surface of the patient and to express it as a point cloud. This could be used to confirm the exact position of the body of the patient and monitor their movements during radiosurgery. The image from the system was matched with the computed tomography (CT) image, and the positional accuracy was compared and analyzed in relation to the existing system to evaluate the accuracy of the setup. Results: The user interface was configured to register the patient and display the setup image to position the setup location by matching the 3D points on the body of the patient with the CT image. The error rate for the position difference was within 1-mm distance (min, -0.21 mm; max, 0.63 mm). Compared with the existing system, the differences were found to be as follows: x=0.08 mm, y=0.13 mm, and z=0.26 mm. Conclusions: We developed a surface-guided repositioning and monitoring system that can be customized and applied in a radiation surgery environment with an existing linear accelerator. It was confirmed that this system could be easily applied for accurate patient repositioning and inter-treatment motion monitoring.

• Maxillofacial Plastic and Reconstructive Surgery
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• 제40권
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• pp.30.1-30.6
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• 2018

Background: The purpose of the present study was to investigate the differences in the position and shape of the anterior loop of the inferior alveolar nerve (ALIAN) in relation to the growth pattern of the mandibular functional subunit. Methods: The study was conducted on 56 patients among those who had undergone orthognathic surgery at the Gangnam Severance Hospital between January 2010 and December 2015. Preoperative computerized tomography (CT) images were analyzed using the Simplant OMS software (ver.14.0 Materialise Medical, Leuven, Belgium). The anterior and inferior lengths of ALIAN (dAnt and dInf) and each length of the mandibular functional subunits were measured. The relationship between dAnt, dInf, and the growth pattern of the mandibular subunits was analyzed. Results: The length of the anterior portion of ALIAN (dAnt) reached 3.34 ± 1.59 mm in prognathism and 1.00 ± 0.97 mm in retrognathism. The length of the inferior portion of ALIAN (dInf) reached 6.81 ± 1.33 mm in prognathism and 5.56 ± 1.34 mm in retrognathism. The analysis of Pearson's correlation coefficiency on all samples showed that the lengths of functional subunits were positively correlated with the loop depth. The length of the symphysis area in prognathic patients was positively correlated with the anterior loop depth (p = 0.005). Conclusions: Both the anterior and inferior length of ALIAN are longer in prognathic patients. Especially, it seems to be associated with the growth of the symphysis area.