• Title/Summary/Keyword: 2p24

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The Significance of 24-Hour Esophageal pH Monitoring in Children with Recurrent Vomiting or Regurgitation (반복성 구토 또는 역류증 환아에서 24시간식도 산도 측정의 의의)

  • Lee, So-Hyun;Lee, Chang-Han;Chung, Ki-Sup
    • Pediatric Gastroenterology, Hepatology & Nutrition
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    • v.2 no.2
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    • pp.139-146
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    • 1999
  • Purpose: The aim of this study was to evaluate the clinical significance of 24 hour pH monitoring in the pediatric patients with recurrent vomiting or regurgitation. Methods: We performed 24 hour pH monitoring on 87 pediatric patients with recurrent vomiting or regurgitation using GastrograpH with glass electrode. The pathologic GER was determined by the reflux index (RI). RIs>10% were considered positive in patients <1 year of age, whereas RIs of >5% were positive in other age groups. We evaluated the mean and standard deviation of the reflux parameters between physiologic and pathologic GER groups, and also compared the reflux indices of each group with respect to time zones of the day. Results: Pathologic GER was found in 32 of 87 patients (36.8%), and the age incidence included 32.5% in infants <6 months old, 13.3% in infants aged 6 months-1 year old, 61.5% in children aged 1~2 years old, 14.3% in children aged 2~3 years old and 66.7% in children >3 years old. In physiologic GER patients, the RI was $3.7{\pm}2.9%$ for the patients <1 year old (group A), and $1.8{\pm}1.5%$ for those ${\geq}1$ year old (group B) which was statistically significant between the 2 age groups (p=0.02). The number of long refluxes more than 5 minutes was significantly increased (p=0.03) in group A ($1.7{\pm}1.9$) than in group B ($0.8{\pm}1.0$). The duration of the longest reflux was significantly longer (p=0.007) in group A ($604{\pm}551$ sec) than in group B ($275{\pm}296$ sec). In pathologic GER patients, the RI was $17.7{\pm}11.6%$ for the patients <1 year old and $7.8{\pm}2.9$ for those ${\geq}1$ year old. The number of long refluxes of more than 5 minutes were $8.9{\pm}4.6$ and $3.2{\pm}1.8$, and the duration of the longest reflux were $1955{\pm}2190$ sec and $1093{\pm}706$ sec for each age group. In both physiologic and pathologic GER patients, there was no significant difference of RI among the time zones of the day. Conclusion: Pathologic GER was found in 36.8% of patients. There was significant difference of RI between those <1 year old and those ${\geq}1$ year old in physiologic GER patients. There was no significant difference of RI among the time zones of the day in both pathologic and physiologic groups. In our study, the frequency of pathplogic GER was too much higher in age group of 1~2 years old (61.5%) than in group of 6 months-1 year old (13.3%), which means that further study is needed to determine the pathologic criteria of RI (Vandenplas criteria is >5%) in the age group of 1~2 years old.

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Factors Influencing the Fear of Falling among Community-dwelling Elderly in Korea (지역사회 재가노인의 낙상 두려움 예측요인)

  • Park, Nan Ju;Shin, Yong Soon
    • Journal of the Korea Academia-Industrial cooperation Society
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    • v.20 no.6
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    • pp.278-287
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    • 2019
  • This study was conducted to identify the predictors influencing fear of falling in community-dewelling elderly. A secondary data analysis was performed using data of 65 years or older elderly who participating in the 2014 Korean Elderly Survey(Jun. 11th ~ Sep. 4th 2014). Multivariated logistic regression analysis was used to identify the risk factors of fear of falling. 81.5% of the elderly had fear of falling. There were significant factors, sex(OR=2.87, p<.001), education(OR=1.73, p<.001), presence of cohabiting spouse(OR=1.19, p<.001), experience of falling(OR=6.35, p<.001), arthritis(OR=1.83, p<.001), depression(OR=2.25, p<.001), cognitive deficit (OR=1.24, p<.001), instrumental activities of daily living (OR=1.98, p<.001), exercise(OR=1.29, p<.001) and the number of chronic diseases(over 3: OR=2.53, p<.001, 1~2: OR=1.73, p<.001), predicting fear of falling in community-dwelling elderly. Fear of falling was associated with multifactorial condition, and arthritis was an important factor in chronic disease. This study will provide fundamental information on programming and a policy proposal related to fear of falling.

Subjective Health and Factors of Health-related Quality of Life in Elderly Haenyo (해녀 노인의 건강수준과 건강 관련 삶의 질에 영향을 미치는 요인연구)

  • Chae, Myungah;Kim, Jeung-Im;Choi, Kyung Sook;Han, Ki-Hye
    • Women's Health Nursing
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    • v.24 no.2
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    • pp.105-115
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    • 2018
  • Purpose: To investigate the subjective health and health-related quality of life (HRQoL) in Haenyo. Methods: Subjects were 100 elderly Haenyo in Jeju island who belonged to a fishing-village society. Main variables were activities of daily living (ADL), instrumental ADL (IADL), the HRQoL, subjective health, and depression. Subjective health and differences of HRQoL by variables were analyzed by t-test or ANOVA using IBM SPSS Statistics 23. Hierarchical multiple regression was executed to examine the effects of the major factors on the quality of life. Results: The mean age was 69.9 years, the mean period for diving career was 51.5 years, and work hours per month were 37.8. Comorbidity of diseases was 2.74, and the common health problems were osteoporosis and headache/dizziness. HRQoL was significantly different by age (F=4.52, p=.013), education (F=6.10, p=.003), muljil work years (F=3.93, p=.050), depression (t=-3.04, p=.030), subjective health state (F=30.62, p<.01), and degenerative arthritis (F=-2.38, p=.019). In the final model by hierarchical multiple regression, ADL/IADL (${\beta}=.41$, p<.001), depression (${\beta}=-.29$, p<.001), and subjective health (${\beta}=.43{\sim}.51$, p<.001) were significant and explained 63.5% of the total variance of HRQoL. Conclusion: Haenyo have specific health problems different from those of elderly women in general. ADL/IADL, depression and subjective health affected their HRQoL. It is clear that Haenyos' health problems need further study to improve their health.

Factors Related to Smoking Behavior among High School Students (일 지역 고등학생의 흡연경험 관련 요인)

  • Choi, Won-Hee;Je, Mi-Soon;Lee, Sam-Soon
    • Journal of Korean Public Health Nursing
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    • v.24 no.2
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    • pp.226-236
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    • 2010
  • Purpose: The study investigated factors related to the smoking behavior among 639 high school students in Geoje, Korea. Methods: Data collected by self-reported questionnaires was analyzed by the SPSS WIN 14.0 program with Chi-test, t-test, and multiple logistic regression analysis. Results: Smoking behavior differed by gender (p=.002), school type (p=.001), experience with alcohol consumption (p=.005), family harmony (p=.003), father's smoking (p=.001), academic achievement (p=.010), self-esteem (p=.010), stress (p=.004), and attitude to smoking (p=.0001). Smoking behavior was significantly associated with gender (odds ratio (OR)=0.66, 95% confidence interval (CI)=0.46-0.95), school type (OR=1.52, 95% CI=1.03-2.23), experience with alcohol consumption (OR=0.56, 95%CI= 0.39-0.82), academic achievement (OR=1.98, 95-I=1.20-3.29), attitude to smoking (OR= 0.76, 95%CI=0.69-0.84) and father's smoking (OR=1.59, 95%CI=1.11-2.29). Conclusion: Anti-smoking programs for high school students should especially consider those at higher risk (males in vocational high school with no drinking experience of drinking, lower academic achievement, favorable attitude to smoking, and whose fathers smoke). Community efforts to reduce adult smoking would be advantageous.

Food security and diet quality among urban poor adolescents in Kuala Lumpur, Malaysia

  • Janice Ee Fang Tay;Satvinder Kaur;Wui Wui Tham;Wan Ying Gan;Nik Norasma Che Ya;Choon Hui Tan;Serene En Hui Tung
    • Nutrition Research and Practice
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    • v.17 no.2
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    • pp.269-283
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    • 2023
  • BACKGROUND/OBJECTIVES: This study aimed to examine the food security status of urban poor adolescents and its association with diet quality. SUBJECTS/METHODS: A cross-sectional survey was conducted among 188 adolescents aged 13-18 yrs living in Kuala Lumpur, Malaysia. Household food insecurity and dietary intake data were collected using the Radimer/Cornell hunger and food insecurity instrument and 2-day 24-h dietary recalls, respectively. Diet quality was determined using the Malaysian Healthy Eating Index (HEI). Weight and height were measured and body mass index-for-age, as well as height-for-age z scores were calculated. RESULTS: The present study revealed that 47.9% of the adolescents experienced household food insecurity, 24.5% experienced individual food insecurity, 18.6% household food security, and 9.0% child hunger. The mean score of diet quality was 56.83 ± 10.09, with a significantly lower HEI score among food insecure adolescents (household food insecure, individual food insecure, and child hunger) than household food secure adolescents (P = 0.001). The differences between food secure and food insecure households were found to be significant for energy (P = 0.001) and nutrients including proteins (P = 0.006), carbohydrates (P = 0.005), dietary fiber (P = 0.001), folate (P < 0.001), and vitamin C (P = 0.006). The multiple linear regression showed that adolescents who experienced food insecurity (β = -0.328; P = 0.003) were found to be significantly associated with poor diet quality (F = 2.726; P < 0.01), wherein 13.3% of the variation in the diet quality was explained by the food security status. CONCLUSIONS: Experiencing food insecurity contributed to poor diet quality among urban poor adolescents. Further longitudinal studies are needed to comprehensively understand this association to improve food insecurity and diet quality among urban poor communities.

Application of a Modified Triple Pelvic Osteotomy for Treatment of Hip Dysplasia in Dogs (개의 고관절 이형성 치료를 위한 변형 3중 골반 절골술의 적용)

  • Kim Young-Sam;Lim Ji Hey;Jung Chang-soo;Byeon Ye-eun;Kanaya Tomohiro;Nagaoka Katsuyoshi;Kweon Oh-kyeong
    • Journal of Veterinary Clinics
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    • v.22 no.4
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    • pp.328-335
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    • 2005
  • The objective of this study was to evaluate tire effects of modified triple pelvic osteotomy(TPO). The procedures of modified TPO were composed of two iliac osteotomies and a pubic symphysiotomy at a tittle. Medical records of modified TPO treatment on 36 dogs and of unilateral TPO on 7 dogs were reviewed on the basis of signalment, body weight, operation time, Healing time of osteotomy sites and complications from October 2002 to September 2004. The values of clinical status and hip dysplasia, Norberg angle, percentage of femoral head coverage and pelvic diameter from radiographs taken preoperative, immediately postoperative, 2, 4, 8, 12 and 24 weeks after operation, respectively, were measured. In .unilateral TPO, the dogs could start standing without assistance from $3.0\pm1.0days$ and walking from $8.3\pm0.6days$ (n=3). Mean clinical grade before and 24 weeks after surgery were $2.2\pm0.42$(n=6) and $3.5\pm0.7$ (n=2), respectively. Mean operation time was $107.3\pm38.9$ minutes (n=4). In modified TPO, the dogs were seen to staff standing without assistance from $4.9\pm3.7$ days and walking from $7.3\pm4.8days$ (n=25). Mean clinical grade before surgery and 24 weeks after surgery were $2.3\pm1.5$ (n=27) and $3.2\pm0.7$)(n=9), respectively. Postoperative clinical grade significantly improved against preoperative clinical grade (P<0.01). Mean operation time was $143\pm42.8$ minutes (n=24). This was shorter than time f3r twice unilateral TPO. By comparison with preoperative values, postoperative mean radiographic grade, percentage of femoral head coverage and Norberg angle measured at the recheck time point significantly increased (P<0.01). Mean postoperative pelvic diameter was significantly larger than preoperative pelvic diameter in modified TPO (P<0.01) but not in unilateral TPO. These results indicated that modified TPO was effective technique for the treatment of hip dysplasia in dogs.

Outcome of Pallidal Deep Brain Stimulation in Meige Syndrome

  • Ghang, Ju-Young;Lee, Myung-Ki;Jun, Sung-Man;Ghang, Chang-Ghu
    • Journal of Korean Neurosurgical Society
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    • v.48 no.2
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    • pp.134-138
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    • 2010
  • Objective : Meige syndrome is the combination of blepharospasm and oromandibular dystonia. We assessed the surgical results of bilateral globus pallidus internus (GPi) deep brain stimulation (DBS) in patients with medically refractory Meige syndrome. Methods : Eleven patients were retrospectively analyzed with follow-ups of more than 12 months. The mean follow-up period was $23.1{\pm}6.4$ months. The mean age at time of surgery was $58.0{\pm}7.8$ years. The mean duration of symptoms was $8.7 {\pm}7.6$ years. DBS electrodes were placed under local anesthesia using microelectrode recording and stimulation. After $2.4{\pm}1.3$ days of trial tests, the stimulation device was implanted under general anesthesia. Patients were evaluated using the Burke-Fahn-Marsden Dystonia Rating Scale (BFMDRS). Results : BFMDRS total movement scores improved by 59.8%, 63.5%, 74.1%, 74.5%, and 85.5% during the immediate postoperative period of test stimulation, 3, 6, 12, and 24 months (n = 5) after surgery, respectively. The BFMDRS total movement scores were reduced gradually and the results reached statistical significance in the postoperative period (test period, p < 0.001; 3 months, p < 0.001; 6 months, p = 0.003; 12 months, p < 0.001; 24 months, p = 0.042). There was no statistical difference between 12 months and 24 months. BFM subscores improved by 63.3% for the eyes, 80.9% for the mouth, 68.4% for speech/swallowing, and 87.9% for the neck at 12 months after surgery. The adverse effects were insignificant. Conclusion : The bilateral GPi-DBS can be effective for the treatment of intractable Meige syndrome without significant side effects.

A Study on the Oxidative Damage Induced by UVB Irradiation to Mouse Skin (UVB 조사로 인한 마우스 피부조직의 산화적 손상)

  • Rhie Sung-Ja;Kim Young-Chul
    • Environmental Analysis Health and Toxicology
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    • v.21 no.2 s.53
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    • pp.165-172
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    • 2006
  • The backs with a hair cut of 6-week-old healthy ICR male mice were once exposed to a dose of $400mJ/cm^2$ UVB. An acute dermal inflammation was observed, and the inflamed skins were almost completely cured after 6 days of the exposure. At 24 hours after exposure, the epidermal keratinocytes showed a cell-membrane damage with the destruction of intercellular junctions, agglutination of tonofilaments within the cytoplasm and nucleus damage. The activity of XO showed a significant increase (p<0.05) in up to 144 hours. The activities of CAT and SOD showed a significant decrease (p<0.05) in up to 96 hours, but they were not significantly different from the normal value at 144 hours. The GST activity was significantly decreased (p<0.01) in up to 96 hours, not so at 24 hours. However, that was not significantly different from the normal value at 144 hours. There was a significant decrease (p<0.01) in the contents of TBARS at 48 and 96 hours, without any significant difference at 144 hours. While the content of GSH was significantly lower (p<0.05) at 24 hours, that was not significantly different thereafter up to 144 hours from the normal value. Therefore, it is assumed that skin damage with a dose of $400mJ/cm^2$ UVB irradiation might be caused by the oxidative stress which was resulted from the unbalance of oxygen fret radical generating and scavenging enzymes.

Efficiency and Behavior of P32-labeled Phosphorus in Camellia japonica L in Blooming Stage (개화기(開花期)에 들어선 동백나무(Camellia japonica L)의 P32 표식(標識) 인산(燐酸)의 행동(行動)과 효율(効率)에 대(對)하여)

  • Kim, Jong Man;Kim, Yong Kwan
    • Journal of Korean Society of Forest Science
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    • v.9 no.1
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    • pp.75-80
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    • 1969
  • Traced observations were carried out for efficiency and behavior of Camellia japonica L in bloom stage by employing $p^{32}$-labeled phosphorus, growing in Southern Korea, and the results were as follows. 1) The percentage of phosphorus contained in flowerbud was double the value of the other parts, and the root and the stem were the same patterns in the course of the times. 2) The circulation of the phosphorus in the plant seems to occur within 24 hours, the proportions of the phosphorus at the growing-point and flowerbud had a half of the total phosphorus contained in other parts. 3) Specific activities of each part were notable on the growing-point where, after 24 hours it took more than 80 percent. On the other hand, the efficiency rate which derived from the phosphorus was shown as about 19 percents.

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Use of Lysozyme as a Feed Additive on In vitro Rumen Fermentation and Methane Emission

  • Biswas, Ashraf A.;Lee, Sung Sill;Mamuad, Lovelia L.;Kim, Seon-Ho;Choi, Yeon-Jae;Bae, Gui-Seck;Lee, Kichoon;Sung, Ha-Guyn;Lee, Sang-Suk
    • Asian-Australasian Journal of Animal Sciences
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    • v.29 no.11
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    • pp.1601-1607
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    • 2016
  • This study was conducted to determine the effect of lysozyme addition on in vitro rumen fermentation and to identify the lysozyme inclusion rate for abating methane ($CH_4$) production. An in vitro ruminal fermentation technique was done using a commercial concentrate to rice straw ratio of 8:2 as substrate. The following treatments were applied wherein lysozyme was added into 1 mg dry matter substrate at different levels of inclusion: Without lysozyme, 2,000, 4,000, and 8,000 U lysozyme. Results revealed that, lysozyme addition had a significant effect on pH after 24 h of incubation, with the highest pH (p<0.01) observed in 8,000 U lysozyme, followed by the 4,000 U, 2,000 U, and without lysozyme. The highest amounts of acetic acid, propionic acid (p<0.01) and total volatile fatty acid (TVFA) (p<0.05) were found in 8,000 U after 24 h of incubation. The $CH_4$ concentration was the lowest in the 8,000 U and the highest in the without lysozyme addition after 24 h of incubation. There was no significant differences in general bacteria, methanogen, or protozoan DNA copy number. So far, addition of lysozyme increased the acetate, propionate, TVFA, and decreased $CH_4$ concentration. These results suggest that lysozyme supplementation may improve in vitro rumen fermentation and reduce $CH_4$ emission.