• Title/Summary/Keyword: 2p24

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Changes of carbon-13 Isotope of Dissolved Inorganic Carbon Within Low-pH CO2-rich Water during CO2 Degassing (pH가 낮은 탄산수의 CO2 탈기에 따른 용존탄소동위원소 변화)

  • Chae, Gitak;Yu, Soonyoung;Kim, Chan Yeong;Park, Jinyoung;Bang, Haeun;Lee, Inhye;Koh, Dong-Chan;Shinn, Young Jae;Oh, Jinman
    • Journal of Soil and Groundwater Environment
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    • v.24 no.3
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    • pp.24-35
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    • 2019
  • It is known that ${\delta}^{13}C_{DIC}$ (carbon-13 isotope of dissolved inorganic carbonate (DIC) ions) of water increases when dissolved $CO_2$ degases. However, ${\delta}^{13}C_{DIC}$ could decrease when the pH of water is lower than 5.5 at the early stage of degassing. Laboratory experiments were performed to observe the changes of ${\delta}^{13}C_{DIC}$ as $CO_2$ degassed from three different artificial $CO_2$-rich waters (ACWs) in which the initial pH was 4.9, 5.4, and 6.4, respectively. The pH, alkalinity and ${\delta}^{13}C_{DIC}$ were measured until 240 hours after degassing began and those data were compared with kinetic isotope fractionation calculations. Furthermore, same experiment was conducted with the natural $CO_2$-rich water (pH 4.9) from Daepyeong, Sejong City. As a result of experiments, we could observe the decrease of DIC and increase of pH as the degassing progressed. ACW with an initial pH of 6.4, ${\delta}^{13}C_{DIC}$ kept increasing but, in cases where the initial pH was lower than 5.5, ${\delta}^{13}C_{DIC}$ decreased until 6 hours. After 6 hours ${\delta}^{13}C_{DIC}$ increased within all cases because the $CO_2$ degassing caused pH increase and subsequently the ratio of $HCO_3{^-}$ in solution. In the early stage of $CO_2$ degassing, the laboratory measurements were well matched with the calculations, but after about 48 hours, the experiment results were deviated from the calculations, probably due to the equilibrium interaction with the atmosphere and precipitation of carbonates. The result of this study may be not applicable to all natural environments because the pressure and $CO_2$ concentration in headspace of reaction vessels was not maintained constant as well as the temperature. Nevertheless, this study provides fundamental knowledge on the ${\delta}^{13}C_{DIC}$ evolution during $CO_2$ degassing, and therefore it can be utilized in the studies about carbonated water with low pH and the monitoring of geologic carbon sequestration.

Analysis of Actual Use Situation of Animal Medicine in Hanwoo Farms (한우농가의 동물약품 이용실태 분석)

  • Kim, G.W.;Koo, S.H.
    • Journal of Animal Environmental Science
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    • v.17 no.1
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    • pp.1-10
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    • 2011
  • This study was conducted to investigate the actual situation of animal medicine use in Hanwoo farms, which were a total of 114 farms. Items surveyed were preference of animal medicine, choice criterion, purchase route, purchase frequency, antibiotics substitution products, etc. Data were collected from May to June, 2010. The kinds of animal medicine which preferred in Hanwoo farms is probiotics (40.4%). Whereas the lowest preference is immunizing agent (12.3%). There was significant difference among regional group (p<0.05), and the significant difference was also found in different farm size group (p<0.05). The factor of choice for purchase of animal medicine was efficiency (31.6%), first of all. There was significant difference among regional group (p<0.05). The purchase route of animal medicine was mostly supplied with the help of government (41.6%). The significant difference were showed in regional group (p<0.05). But that was not found in farm size group (p>0.05). The highest frequency at purchasing antibiotics was less than 1 time per 1 year (38.6%). There was statistically significant difference among regional group (p<0.05). However, there was not significant difference among farm size group (p>0.05). Probiotics of antibiotics substitution products was mostly preferred (50.9%).

Cooperative Video Streaming and Active Node Buffer Management Technique in Hybrid CDN/P2P Architecture

  • Lee, Jun Pyo
    • Journal of the Korea Society of Computer and Information
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    • v.24 no.11
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    • pp.11-19
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    • 2019
  • Recently, hybrid CDN/P2P video streaming architecture is specially designed and deployed to achieve the scalability of P2P networks and the desired low delay and high throughput of CDNs. In this paper, we propose a cooperative video streaming and active node buffer management technique in hybrid CDN/P2P architecture. The key idea of this streaming strategy is to minimize network latency such as jitter and packet loss and to maximize the QoS(quality of service) by effectively and efficiently utilizing the information sharing of file location in CDN's proxy server which is an end node located close to a user and P2P network. Through simulation, we show that the proposed cooperative video streaming and active node buffer management technique based on CDN and P2P network improves the performance of realtime video streaming compared to previous methods.

Effect of Scutellariae Radix Water Extract on Hydrogen Peroxide Production in RAW 264.7 Mouse Macrophages (황금(黃芩) 물추출물이 마우스 대식세포의 hydrogen peroxide 생성에 미치는 영향)

  • Park, Wan-Su
    • The Korea Journal of Herbology
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    • v.26 no.1
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    • pp.53-58
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    • 2011
  • Objectives : The purpose of this study is to investigate effects of Scutellariae Radix Water Extract on hydrogen peroxide production in RAW 264.7 mouse macrophages. Methods : Scutellariae Radix produced from South Korea (SK) and Scutellariae Radix produced from China (SC) were extracted by hot water. Effects of SK and SC on hydrogen peroxide production in RAW 264.7 were measured by dihydrorhodamine 123 assay after 2, 4, 20, 24, 28, 44, and 48 h incubation at the concentrations of 10, 25, 50, and 100 ug/mL. Results : SK significantly increase hydrogen peroxide production in RAW 264.7 cells for 2, 4, 20, 24, 28, 44, and 48 h incubation at the concentrations of 10, 25, 50, and 100 ug/mL (P < 0.05). SC also significantly increase hydrogen peroxide production in RAW 264.7 cells for 4, 20, 24, 28, and 48 h incubation at the concentrations of 10, 25, 50, and 100 ug/mL (P < 0.05). For 2 h incubation, SC significantly increase hydrogen peroxide production in RAW 264.7 cells at the concentrations of 10, 25, and 100 ug/mL (P < 0.05). For 44 h incubation, SC significantly increase hydrogen peroxide production in RAW 264.7 cells at the concentrations of 10, 25, and 50 ug/mL (P < 0.05). Conclusions : These results suggest that Scutellariae Radix has the immune - enhancing property related with its increasement of hydrogen peroxide production in macrophages.

Muscle Ultrastructural Changes by Lysosomal Enzymes -2. Scanning Electron Microscopic Studies- (Lysosomal Enzyme에 의(依)한 근육조직(筋肉組織)의 변화(變化) -제(第)2보(報) Scanning Electron Microscopy에 의(依)한 고찰(考察)-)

  • Cho, Moo-Je;Yoon, Tae-Gyu;Bailey, Milton E.
    • Korean Journal of Food Science and Technology
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    • v.10 no.1
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    • pp.36-45
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    • 1978
  • Surface ultrastructural changes in endomysial connective tissue, sarcolemma and transverse ridges of bovine psoas muscle produced by leukocyte lysosomal enzymes in vitro at different pH (pH 7.0 and 4.0), temperature (37 and $4^{\circ}C$) and time interval (12, 24 hours at $37^{\circ}C$ and 36, 168 hours at $4^{\circ}C$ were studied by scanning electron microscope. Muscle incubated with leukocyte lysosomal enzymes at pH 7.0 produced severe degradation of endomysial and sarcolemmal connective tissue and transverse ridges but at pH 4.0 endomysial and sarcolemmal structures remain moderately stable and tranverse ridges are very stable even after 24 hours incubation at $37^{\circ}C$ and 7 days incubation at $4^{\circ}C$.

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Safety of Administering Intravenous CT Contrast Agents Repeatedly or Using Both CT and MRI Contrast Agents on the Same Day: An Animal Study

  • Heejin Bae;Hyewon Oh;Ga Bin Park;Yong Eun Chung
    • Korean Journal of Radiology
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    • v.25 no.3
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    • pp.257-266
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    • 2024
  • Objective: To investigate molecular and functional consequences of additional exposures to iodine- or gadolinium-based contrast agents within 24 hours from the initial intravenous administration of iodine-based contrast agents through an animal study. Materials and Methods: Fifty-six Sprague-Dawley male rats were equally divided into eight groups: negative control, positive control (PC) with single-dose administration of CT contrast agent, and additional administration of either CT or MR contrast agents 2, 4, or 24 hours from initial CT contrast agent injection. A 12 µL/g of iodinated contrast agent or a 0.47 µL/g of gadolinium-based contrast agent were injected into the tail vein. Serum levels of blood urea nitrogen, creatinine, cystatin C (Cys C), and malondialdehyde (MDA) were measured. mRNA and protein levels of kidney injury molecule-1 (KIM-1) and neutrophil gelatinase-associated lipocalin (NGAL) were evaluated. Results: Levels of serum creatinine (SCr) were significantly higher in repeated CT contrast agent injection groups than in PC (0.21 ± 0.02 mg/dL for PC; 0.40 ± 0.02, 0.34 ± 0.03, and 0.41 ± 0.10 mg/dL for 2-, 4-, and 24-hour interval groups, respectively; P < 0.001). There was no significant difference in the average Cys C and MDA levels between PC and repeated CT contrast agent injection groups (Cys C, P = 0.256-0.362; MDA, P > 0.99). Additional doses of MR contrast agent did not make significant changes compared to PC in SCr (P > 0.99), Cys C (P = 0.262), and MDA (P = 0.139-0.771) levels. mRNA and protein levels of KIM-1 and NGAL were not significantly different among additional CT or MR contrast agent groups (P > 0.05). Conclusion: A sufficient time interval, probably more than 24 hours, between repeated contrast-enhanced CT examinations may be necessary to avoid deterioration in renal function. However, conducting contrast-enhanced MRI on the same day as contrast-enhanced CT may not induce clinically significant kidney injury.

Risk Factors and Level of Acute Post-Operative Pain in Surgical Patients During the First 48 Hours after Surgery (수술 후 첫 48시간 동안의 수술후 통증에 영향을 미치는 요인)

  • Lee, Yoonshin;Son, Jaesoon;Yoon, Haesang
    • Journal of Korean Biological Nursing Science
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    • v.16 no.3
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    • pp.226-234
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    • 2014
  • Purpose: This prospective study was designed to investigate the incidence of acute postoperative pain (APP) ${\geq}4$ and the risk factors of APP${\geq}$ for the first 48 hours after surgery. Methods: Data from 531 surgical patients were collected from November, 2009 to May, 2010. APP was assessed from the time of arrival at the Post Anesthetic Care Unit (PACU) to the end of the post-operative 48 hours. Risk factors of APP${\geq}$ were analyzed by logistic regression analysis. Results: The incidence of APP ${\geq}4$ was 58.8% for the first postoperative 4 hours; 33.5%, 24 hours; 11.1%, 48 hours. The score of pain was 5.55, the highest on arriving at PACU; 5.03 at postoperative 30 minutes; 4.03 at 1 hour; 3.96 at 4 hours; 2.76 at 24 hours; 1.44 at 48 hours Risk factors for APP ${\geq}4$ were females (Odds ratio [OR], 1.94; p=.013), general anesthesia (OR, 4.29; p<.001) and patient controlled analgesia (PCA) (OR, 2.83; p<.001) at 4 hours after operation; body mass index (BMI) ${\geq}25$ (OR, 1.80; p=.009), duration of surgery ${\geq}1$ hour (OR, 2.87; p=.037), general anesthesia (OR, 3.99; p<.001) and PCA (OR, 6.23; p<.001) at 24 hours; general anesthesia (OR, 3.53; p=.003) and PCA (OR, 3.01; p=.013) at 48 hours. Conclusion: Surgical patients with BMI ${\geq}25$, PCA and general anesthesia seem to have a higher incidence of pain ${\geq}4$ through the first postoperative 48 hours.

Effects of Feeding Bupleurum falcatum L. on Performance, Blood Component and Hormone Concentration in Broiler Breeder Hens (육용종계 사료에 시호(Bupleurum falcatum L.)의 첨가가 생산능력, 혈액의 성상 및 호르몬 분비에 미치는 영향)

  • Park J.H.;Kang C.W.;Ryu K.S.
    • Korean Journal of Poultry Science
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    • v.33 no.1
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    • pp.49-55
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    • 2006
  • An experiment was conducted to investigate the effects of feeding Bupleurum falcatum L.(BFL) on performance, blood component and hormonal secretion in broiler breeder hens. A total of 800 broiler breeder hens were allotted to four treatments(BFL ; 0, 0.5, 1.0, 2.0%) with four replications for eight weeks. Weight gain was not significantly different between the groups in growing period($20{\sim}24$ weeks), but egg production and egg mass of broiler breeder hens fed BFL were significantly(p<0.05) higher than those of the control groups in laying period($24{\sim}28$ weeks). Dietary BFL did not affect serum triglyceride concentration, whereas serum cholesterol concentration was significantly increased(p<0.05) in 2.0% BFL-fed groups. No statistical differences were found in serum glucose, Ca, P, Mg, total protein, albumin, GGT, AST, ALT and BUN concentrations. However, albumin/globulin ratio was statistically higher in BFL-fed groups compared to the control groups(p<0.05). Serum estrogen concentrations were significantly increased by feeding a diet containing 0.5% BFL, but progesterone were not influenced. Serum IGF-I of BFL groups was greater than that of control groups at 28 weeks(p<0.05). In conclusion, the results suggest that the dietary addition of BFL into broiler breeder diets improved egg production, serum estrogen and IGF-I concentration, and decreased serum cholesterol concentration and albumin/globulin ratio.

Interaction of HIV-1 Core p24 Antigen with Human Monocytic Cell Line THP1 Results in TNF-${\alpha}$ Dependent Secretion of Matrix Metalloproteinase-9

  • Sung, Ji-Hye;Yoo, Seung-Hee;Park, Hae-Kyung;Chong, Young-Hae
    • The Journal of the Korean Society for Microbiology
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    • v.35 no.1
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    • pp.9-18
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    • 2000
  • Immunological mechanisms involving the release of inflammatory factors by HIV-1 infected microglia in the brain have been implicated in the pathogenesis of HIV dementia (HIVD). Since the regulation of matrix metalloproteinases (MMPs) activity can be influenced by variety of inflammatory mediators, this study was undertaken to look for a correlation between the MMP-9 release and the production of TNF-${\alpha}$ in response to HIV-1 p24 in the human monocyte cell line THP-1 as a model for microglia. First, it was shown that HIV-l core p24 antigen induced THP-1 to secrete MMP-9 in a dose response manner while it elicited a little effect on MMP-2 release in human astroglial cell line T98G. Next, it was found that p24 induced THP-1 to secrete TNF-${\alpha}$ without prior differentiation into macrophages by phorbol myristate acetate (PMA) treatment. Furthermore, anti-TNF-${\alpha}$ neutralizing antibodies significantly blocked p24-induced MMP-9 release in a dose dependent manner. Our data indicate that p24 antigen induces monocytic MMP-9 release by triggering up-regulation of TNF-${\alpha}$ secretion.

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Body Weight Control Behavior and Obesity Stress of College Women (여대생의 체중조절행위와 비만스트레스)

  • Kang, Yang-Hee;Kim, Kyung-Hee
    • The Journal of the Korea Contents Association
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    • v.15 no.2
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    • pp.292-300
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    • 2015
  • This study was conducted to investigate weight control behavior and obesity stress of college women. The data were collected from September 7 to September 13 of 2013 and the subjects were 213 college women in C city of Gyoung-nam Province. The data were analyzed by SPSS 20.0 program using descriptive statistics, t-test, ANOVA, Scheffe's test. The score of obesity stress was moderate($18.26{\pm}5.66$). The level of obesity stress was affected by various general characteristics and weight control behavior characteristics including economic status(F=3.99, p=0.020), figure recognition(F=14.41, p<.001), satisfaction of body figure(F=15.88, p<.001), interest of weight control(F=4.82, p=.001), control of food amount(F=2.41, p=.050), body figure compulsion(F=24.06, p<.001), experience of dieting (F=6.04, p<.001), sleeping hours(t=2.10, p=.036), desired losing weight (F=10.47, p<.001). Therefore, it is necessary to be considered these variables during development of body weight control programs for college women.