• 유통과학연구
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• 제13권10호
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• pp.51-56
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• 2015

Purpose - This study examines Chinese P2P investment decision processes from a behavioral economics approach. Research design, data, and methodology - We analyze the online P2P investment product purchase decisions of 241 respondents in China, March 2015 to May 2015. T-tests were conducted to determine whether the framing effect influenced investor investment preferences. The Association Rule was used to identify the framing effect of respondent demographic characteristics on joint decisions regarding stable or risky investment products. Results - There are significant differences between the two groups (positive framing and negative framing) and their product-choosing behavior. In the positive framing group, female investors, young investors, investors with non-financial occupations and with limited or no experience, preferred stable P2P investment products. In contrast, in the negative framing group, investors with extensive investment experience preferred risky investment products. Conclusions - The framing effect influences investor choices in online P2P investment products. It is necessary to implement comprehensive supervision and full information disclosure regarding P2P investment products. P2P investment websites can also adopt different marketing strategies according to investor gender and age.

• Clinics in Shoulder and Elbow
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• 제13권1호
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• pp.53-57
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• 2010

목적: 1, 2단계 충돌 증후군과 회전근 개 파열이 있는 환자 사이의 근력 결핍 차이를 비교하였다. 대상 및 방법: 43명의 1, 2단계 충돌 증후군 환자 군 (1군)과 21명의 회전근 개 파열 환자 군 (2군)을 대상으로 하였다. 외회전, 내회전, 외전과 내전의 근력을 $60^{\circ}/sec$ 등속성 검사로 평가했다. 몸무게로 보정한 양측의 최대 우력, 총 일의 양, 평균 근력과 동측의 주동근과 길항근의 비율을 측정하였다. 결과: 양 군에서 몸무게로 보정한 최대 우력의 결핍은 외전에서 각각 $28.48{\pm}23.76%$ (1군), $29.12{\pm}32.81%$ (2군) (p=0.929), 내전에서 $7.20{\pm}13.98%$, $18.94{\pm}19.52%$ (p=0.021), 외회전에서 $16.88{\pm}13.76%$, $25.80{\pm}24.07%$ (p=0.221), 내회전에서 $14.15{\pm}25.67%$, $29.02{\pm}35.06%$ (p=0.059)로 측정되었다. 평균 근력과 총 일의 양에서 2군은 1군과 비교하여 내전력과 내회전력의 결핍이 유의하게 증가되었다. 결론: 2군에서 1군보다 더 큰 근력 결핍을 보였다. 1, 2단계 충돌 증후군 에서 3단계로 진행 시내회전과 내전 근력 결핍 변화가 더 크게 나타날 가능성이 있다.

• 한국산학기술학회논문지
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• 제16권10호
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• pp.6852-6859
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• 2015

본 연구는 섬진강에서 염분구배에 따른 일본채첩의 분포와 성장특성을 조사하기 위해서 14개 정점에서 봄과 이른 여름사이 현장조사를 수행하였다. 저층의 염분은 상류 정점14에서 1.02 psu로 가장 낮게, 광양만 정점1에서 32.9 psu로 가장 높게 나타났고, 섬진강 상류로 올라갈수록 지수함수적으로 염분이 감소하는 것을 파악하였다. 특히 정점11에서 염분이 급격하게 떨어져 15 psu전후를 유지하였고, 이 구간을 염분전이지역이라고 할 수 있었다. 일본재첩의 분포는 염분농도구배에 따라서 의존되는 양상을 보였고, 최고밀도는 정점13에서 $2,102inds.m^{-2}$ 로 가장 높았고, 다음으로 정점11에서 $1,507inds.m^{-2}$로 관찰되었다. 여기서, 염분의 차이에 따른 일본재첩의 성장특성에 초점을 두어 평가한 결과, 일본재첩 각장에 대한 전중량의 관계는 정점13($R^2=0.91$, P<0.001)에서 정점11($R^2=0.72$, P<0.001)보다 유의하게 높은 상관성을 보였다. 반대로, 각장대비 각고와 각폭에 대한 관계는 정점13보다 정점11에서 높은 상관성이 관찰되었다(P<0.001). 아울러 비만도지수 또한 정점13에서 채집한 재첩이 정점11보다 유의하게 높게 나타났다(t-test= -22.87, P<0.001). 이와 같은 결과는 염분에 대한 스트레스로부터 방어기작의 차이로 판단되며, 염분이 낮은 정점13에서는 패각보다 체성장에 더 많은 에너지를 투입하고, 염분의 변화가 심한 정점11에서는 재첩의 육질을 보호하기 위해서 패각을 튼튼하게 만드는 생존전략으로 판단된다. 이와 같은 염분에 대한 방어기작의 차이는 생태학적으로 일본재첩의 생존전략에 중요한 역할을 하고 있는 것으로 기대된다.

• Asian Pacific Journal of Cancer Prevention
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• 제13권12호
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• pp.6397-6401
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• 2012

Background: No factor has thus far been identified to predict the efficacy of bevacizumab therapy for colorectal cancer. We here therefore studied PTEN, VEGF, HER2 and p53 by immunohistochemistry as possible prognostic and predictive factors. Materials and Methods: A total of 34 retrospectively collected tumor samples were evaluated, all from patients receiving bevacizumab-based regimens. VEGF-A, PTEN, HER2, p53 were assessed and data was compared with clinicopathologic characteristics of patients and the bevacizumab response rate. Results: In this study, the median age of the 34 metastatic colorectal cancer patients was 55.5 (24-75), twelve (35.3%) being women and 22 (64.7%) men. PTEN, VEGF, HER2, p53 expressions were compared with bevacizumab response and other chacteristics of disease. Statistical significant differences were not found between bevacizumab response rates and different expression levels of VEGF, PTEN, HER2 and p53 (respectively p=0.256, p=0.832, p=0.189, p=0.131). However, a survival difference was noted in the VEGF expression negative group (median OS:55 months; 95%CI, 22-88 months) (p=0.01). There was no statistically significant OS difference in other groups (PTEN p=0.6, HER2 p=0.189, p53 p=0.13). Conclusions: We did not find any predictive factor for BV therapy in our study. VEGF negative expression could be an important prognostic factor in metastatic colorectal carcinoma.

• Bulletin of the Korean Chemical Society
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• 제8권2호
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• pp.73-79
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• 1987

In this work we have investigated temperature dependence of spin-rotational relaxation rate, $(1/T_1)_{SR}$, of methyl carbon-13's in 2-bromo-p-xylene, 2,5-dimethylaniline, and 2,5-dimethylanisole and have found that temperature behaviors of two methyl carbon-13's in ortho- and meta-position, respectively, are substantially different. It has been confirmed that the modified Burke-Chan model proposed by Park et al. can nicely explain different temperature dependence of $(1/T_1)_{SR}$ for these two methyl carbon-13's while the original Burke-Chan model fails to do so.

• Genomics & Informatics
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• 제2권2호
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• pp.75-80
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• 2004

In a variety of animal species, the perinatal exposure of experimental animals to the 2,3,7,8-tetrachlorodibenzo­p-dioxin (TCDD) leads to the immune dysfunction, which is more severe and persistent than that caused by adult exposure. We report here the changes of gene expression and the identification of the marker-genes representing the dioxin exposure. The expressions of the transcripts were analyzed using the 11 K oligonucleotide­microarray from the bone marrow cells of male C57BL/6J mice after an intraperitoneal injection of $1{\mu}g$ TCDD/kg body weight at various time intervals: gestational 6.5 day(G6.5), 13.5 day(G13.5), 18.5 day(G18.5), and postnatal 3 (P3W)and 6 week (P6W). The type of self-organizing maps(SOM) representing the specific exposure dioxin could be identified as follows; G6.5D(C14), G13.5D(C0, C5, C10, C18), G18.5D(7): P3W(C2, C21), and P6W(C4, C15, C20). The candidate marker-genes were restricted to the transcripts, which could be consistently expressed greater than $\pm$2-fold in three experiments. The resulting candidates were 85 genes, the characteristics of that were involved in cell physiology and cell functions such as cell proliferation and immune function. We identified the biomarker-genes for dioxin exposure: smc -like 2 from SOM C14 for the dioxin exposure at G6.5D, focal adhesion kinase and 6 other genes from C0, and protein tyrosine phosphatase 4a2 and 3 other genes from C5 for G13.5D, platelet factor 4 from C7 for G18.5D, fos from C2 for P3W.

• 자연과학논문집
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• 제16권1호
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• pp.15-29
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• 2005

내열성의 cyclomaltodextrin glucanotransferase (CGTase)를 이용하여 열에 안정한 싸이클린 텍스트린 (CD)을 생산하기 위하여 매우 높은 CGTase 활성을 보이는 고열성이며 호알카리성인 B-13세균을 분리하여 형태적, 생리학적 특성과 16S 리보솜 RNA 서열분석 등을 통하여 Bacillus cereus B-13으로 동정하였다. Bacillus cereus B-13 2% 가용성 전분, 1% 효모 추출물, 1% $Na_2CO_3$ 등을 함유하는 SYC 배지 (pH 8.5)에 접종하여 $50^{\circ}C$에서 24시간 배양하였을 때 최고의 CGTase 활성(130 U/ml)을 보였다. 또한 부분 정제된 CGTase의 작용 최적 온도와 pH는 각각 $60^{\circ}C$, pH 8.5-9.0 이었고 $80^{\circ}C$이하와 pH5.0-10.0에서 안정하였다. 1% 가용성 전분을 부분 정제한 CGTase와 작용시켰을 때 49%의 CD 수율을 보였다.

• Asian Pacific Journal of Cancer Prevention
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• 제13권1호
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• pp.225-229
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• 2012

Background: Males have a higher prevalence of hepatocellular carcinoma (HCC) than females in general, but the reasons for the sex disparity are still obscure. DNA copy number alteration (CNA) is a major feature of solid tumors including HCC, but whether CNA plays a role in sex-related differences in HCC development has never been evaluated. Methods: High-resolution array comparative genomic hybridization (CGH) was used to examine 17 female and 46 male HCC patients with chronic hepatitis B virus (HBV) infection in Shanghai, China. Two-tailed Fisher's exact or ${\chi}^2$ tests was used to compare CNAs between females and males. Results: The overall frequencies and patterns of CNAs in female and male cases were similar. However, female HCC tumors presented more copy number gains compared to those in males on 1q21.3-q22 (76.5% vs. 37.0%, P = 0.009), 11q11 (35.3% vs. 0.0%, P = 0.0002) and 19q13.31-q13.32 (23.5% vs. 0.0%, P = 0.004), and loss on 16p11.2 (35.3% vs. 6.5%, P = 0.009). Relative to females, male cases had greater copy number loss on 11q11 (63.0% vs. 17.6%, P = 0.002). Further analyses showed that 11q11 gain correlated with 19q13.31-q13.32 gain (P = 0.042), 11q11 loss (P = 0.011) and 16p11.2 loss (P = 0.033), while 1q21.3-q22 gain correlated with 19q13.31-q13.32 gain (P = 0.046). Conclusions: These findings suggest that CNAs may play a role in sex-related differences in HBVassociated HCC development.

• KSBB Journal
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• 제13권4호
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• pp.399-403
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• 1998

This study was carried out to optimize the concentration of Ca2+ and pH of fusion medium which affected electrofusion frequency of protoplasts isolated from Nicotiana tabacum L. (cv. BY4) mesophyll cells and callus. The protoplasts were electrofused in the fusion media containing two different Ca2+ concentrations and three different pH regions. Fusion frequency was lower in the fusion medium containing only 13% mannitol as osmotic stabilizer. However, higher degree of fusion frequency (47.3%) was observed in the fusion medium containing 50mM CaCl2 at pH 10.5 than any other conditions. Cell viability was decreased by Ca2+ and high pH treatment in the fusion media, while fusion frequency was increased. It is concluded that Ca2+ is involved in electrofusion of protoplasts.

• 정보처리학회논문지C
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• 제13C권4호
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• pp.389-396
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• 2006

P2P(Peer to Peer)는 오늘날 가장 주목 받는 파일 공유 시스템으로 현재 네트워크 트래픽의 50% 가량을 점유하고 있을 정도로 많은 콘텐츠의 유통경로가 되고 있다. 이처럼 P2P는 가장 큰 콘텐츠 유통 경로로 활용되기도 하지만 콘텐츠의 가장 큰 불법 유통 경로로 활용되기도 하며 최근에 들어 음악산업뿐만 아니라 영상산업 전반으로 불법 유통을 야기시키고 있으나 현재 이를 방지하면서 P2P의 장점을 최대한 살릴 수 있는 DRM(Digital Right Management)이 적용된 P2P 모델이 제시되지 못하고 있다. 이에 본 논문에서는 기존 DRM 기능들을 변형하여 기존에 P2P 모델에 적합한 형태로 적용함으로써 기존의 P2P 모델구조를 변형시키지 않고 P2P의 높은 확장성(Scalability)과 분산 처리 성능을 지원할 수 있는 콘텐츠 보호를 위한 DRM이 적용된 P2P 모델을 제안한다.