• Title/Summary/Keyword: 25(OH)D

Search Result 841, Processing Time 0.033 seconds

Effect on Insecticide Susceptibility of Lissorhoptrus oryzophilus Fed on Carotenoid-Biofortified Rice Variety (비타민 A 강화벼 급이가 벼물바구미(Lissorhoptrus oryzophilus)의 살충제 감수성에 미치는 영향)

  • Oh, Sung-Dug;Lee, Ki-Jong;Park, Soo-Yun;Ryu, Tae-Hun;Kim, Jae-Kwang;Sohn, Soo-In;Kim, Jin-Seo;Ha, Sun-Hwa;Park, Jong-Sug;Ahn, Byung-Ohg;Cho, Hyun-Suk;Suh, Sang-Jae
    • Korean Journal of Environmental Agriculture
    • /
    • v.31 no.3
    • /
    • pp.286-292
    • /
    • 2012
  • BACKGROUND: The carotenoid-biofortified (PAC) rice was generated by inserting phytoene synthase (Psy) and carotene desaturase (Crtl) genes isolated from Capsicum annuum cv. Nockwang and Pantoea ananatis into the genome of a conventional variety of rice (Nakdongbyeo). In our present study, we studied the effects on insecticide susceptibility of Rice Water Weevil (Lissorhoptrus oryzophilus). METHODS AND RESULTS: The L. oryzophilus were fed on carotenoid-biofortified (PAC) rice and its near non-genetically modified (GM) counterparts (Nakdongbyeo) under $25{\pm}1^{\circ}C$, humidity of $60{\pm}5%$, and photoperiod 16L:8D for more than 60 days. Ten adults were soaked in the Clothianidin SC solution for 5 second in different concentrations, and were detected the mortalities after 24, 48 and 72 hours respectively. Every experiment was conducted with three replications. The cumulative mortalities of L. oryzophilus exposed to Clothianidin SC were similar between two types of feed administration. CONCLUSION: The results of this study suggested that carotenoid-biofortified rice might not affect the insecticide susceptibilities of Lissorhoptrus oryzophilus.

Improvement of Pulmonary Function after Administration of Azithromycin in a Patient with Bronchiolitis Obliterans: a Case Report (Azithromycin 투여로 폐기능이 호전된 폐쇄성 세기관지염 1예)

  • Oh, Ji Hye;Kim, Kyung Chan;Kim, Sung Woo;Hyun, Dae Sung;Lee, Sang Chae;Bae, Sung Hwa;Jung, Kyung Jae;Kwon, Kun Young
    • Tuberculosis and Respiratory Diseases
    • /
    • v.65 no.5
    • /
    • pp.410-415
    • /
    • 2008
  • Bronchiolitis obliterans (BO) is a serious noninfectious complication following an allogeneic bone marrow transplant (BMT). A 21-year-old female received an allogeneic BMT as a treatment for myelodyplastic syndrome. Four months after the BMT, progressive dyspnea developed and BO was also diagnosed by a lung biopsy. The patient was administered steroid and immunosuppressive agents for 1 year but there was no improvement in pulmonary function. Azithromycin was prescribed (500 mg q.d. for 3 days followed by 250 mg three time a week) because macrolides might decrease the inflammatory reaction leading to BO. The patient's pulmonary function improved after administration of azithromycin for 1 year. The forced expiratory volume in a one second ($FEV_1$) increase was 220 mL (28.2%) and the forced vital capacity (FVC) increase was 460 mL (25.7%). We report the improvement in the pulmonary function after the administration of azithromycin for 1 year in a patient with BO after a BMT.

Seasonal variation in growth of Berkshire pigs in alternative production systems

  • Park, Hyeon-Suk;Oh, Sang-Hyon
    • Asian-Australasian Journal of Animal Sciences
    • /
    • v.30 no.5
    • /
    • pp.749-754
    • /
    • 2017
  • Objective: The objective of the present study was to investigate the effects of farrowing month (FM), parity and sex on the growth performance of Berkshire swine raised in alternative production systems. Methods: A total of 40 farrowing records from 27 sows and 1,258 body weight (BW) records from 274 piglets collected over a two-year period were used for the analysis. The BWs were recorded at birth, weaning (28 d), 56, 84, 112, and 140 days. Any BW not recorded on schedule was recalculated to conform the days of age among corresponding BW records, using growth curves drawn with polynomial functions whose power was determined by the number of existing observations for each individual. Results: The mean parity (${\pm}$standard deviation) of the sows was $3.42{\pm}2.14$. The sows that farrowed in June had the lowest number of total born with an average of $6.25{\pm}2.22$ piglets per sow. However, the lowest average number of piglets weaned at day 28 was found in sows that farrowed in May, as well as the highest number recorded for the stillborn piglets with an average of 2.67 piglets per sow. Moreover, the smallest increase in weight from birth to weaning occurred in piglets that were farrowed in May, which also corresponds with the average daily gain (ADG) of 0.29 kg and the last recorded weight measurement on day 140 of $41.69{\pm}1.45kg$. Contrastingly, the highest growth rate was found among pigs farrowed in June, with the largest increase in weight of 7.55 kg from birth to weaning, the highest ADG of 0.51 kg from birth to 140 day of age and the highest BW of $74.70{\pm}1.86kg$ recorded on day 140. Conclusion: Pigs farrowed in June also had the least number of piglets that died between birth and weaning. The zone of thermal comfort found in sows reared in indoor confinement systems did not improve the reproductive performance of the sows reared in an outdoor, alternative production system, while the growth performance of the piglets was improved when the ambient temperature was consistently hot or consistently cold.

A Study in Preparation of $^{113m}In$ colloid as Scanning Agent and it's Organ Distribution in Rats (주사용(走査用) $^{113m}In$ 교질(膠質)의 조제(調製) 및 흰쥐에서의 장기분포(臟器分布)에 관(關)한 연구(硏究))

  • Koh, Chang-Soon;Rhee, Chong-Heon;Chang, Ko-Chang;Hong, Chang-Gi D.
    • The Korean Journal of Nuclear Medicine
    • /
    • v.3 no.1
    • /
    • pp.73-82
    • /
    • 1969
  • The newly developed diagnostic method with application of $^{113}Sn-^{113m}In$ cow system ($^{113}Sn:\;T\frac{1}{2}$ 118 days, $^{113m}In:\;T\frac{1}{2}$ 1.7 hrs, 390 Kev, Single ${\gamma}$) has the remarkable advantages such as increased diagnostic ability by single large dose administration of $^{113m}In$ with no subsequent radiation hazard and shortened examining time. We reformed the research of following scope with the use of developed $^{113}Sn-^{113m}In$ cow (25 mCi) generator: The sizes of particles produced under various conditions were investigated, and possibility for application to the scannings of various organs such as brain, liver, lung, bone marrow and blood pool etc. were studied. Results: $^{113m}InCl_3$ solution eluted from diluted HCl solution (pH 1.5) passed through $^{113}Sn-^{113m}In$ generator, and there can be produced various sized particles of colloidal indium. And there observed the state of distribution of $^{113m}In$ in each organ which showed many differences according to the particle sizes of colloidal indium. The results are stated as follows: 1. The adjustment of pH is the most important factor in making the desirable particle size of colloidal indium. The colloid for blood pool showed the highest level as 7.1%/gm blood, at pH 1.7, the colloid of pH 3.5 for liver scanning showed the highest level, 88.4%, in the liver, the colloid pH 6 showed the highest level, 3.1%, in the spleen, and the colloid of pH 11.0 showed the highest level, 85.3%/gm, in the lung. 2. The colloid for liver scanning made with NaCl-NaOH system showed the highest liver uptake at pH 7.2, and at either higher or lower pH than 7.2 showed decrease of liver uptake more or less. 3. The activity of $^{113m}In$ eluted through $^{113}Sn-^{113m}In$ generator indicated over 90% in the initial 4 ml, and particularly 88.1%-86.0% in the initial 2 ml. 4. The incubation time, tempertaure and mechanical irritation related to colloid formation and coating of colloid were not the definite condition of influence.

  • PDF

Consideration on Changes of Density Stratification in Saemangeum Reservoir (새만금호 내 밀도 성층 변화 고찰)

  • Oh, Chan-Sung;Choi, Jung-Hoon
    • Journal of the Korean Society for Marine Environment & Energy
    • /
    • v.18 no.2
    • /
    • pp.81-93
    • /
    • 2015
  • The comprehensive master plan in November 2010 on Saemangeum internal development has been released, and there is a need for complementary measures related to in-situ monitoring methods in order to acquire water temperature (T) and salinity (S) data. Thus, these data are monitored and analyzed by Korea Rural Community Corporation continuously. The purposes of current study are to evaluate the distributions of seasonal T and S, sigma-t, and stratification parameter and to compare annual stratification system in 2011 and 2012. To achieve these objectives, monthly vertical changes of T, S, and sigma-t, which are reproduced by a kriging technique, have been analyzed. In summer, the temperature difference between surface and bottom layers varies from 2 to $3^{\circ}C$, and the stratification of T is considerably weak. The stratification of S occurs abruptly within depth of EL. (-)5 to EL. (-)10 m. Therefore, stratification is induced by sudden increasing of water inflow amount due to a localized downpour during the rainy season, and these stratification processes are strongly influenced by inflowing a fresh water from watersheds in estuary environment.

Clinical Study of Patients with Elevated Troponin-I in Near-hanging Injury (심근효소 상승 유무에 따른 목맴 환자들의 임상적 특성)

  • Shin, Hyun Goo;Park, Jun Bum;Kim, Chang Sun;Oh, Jae Hoon;Cho, Young Suk;Park, Sae Hoon;Je, Sang Mo;Choi, Hyuk Joong;Kang, Bo Seung;Lim, Tae Ho;Kang, Hyung Goo
    • Journal of Trauma and Injury
    • /
    • v.25 no.4
    • /
    • pp.196-202
    • /
    • 2012
  • Purpose: This study aimed to recognize the frequency of near-hanging patients with elevated Troponin-I (Tn-I), to obtain information necessary for treatment and prediction of prognosis by analyzing the clinical feature of near-hanging patients, and to evaluate the relevance of elevated Tn-I to abnormal result of other cardiac-related examinations. Methods: A retrospective review for the near-hanging patients, clinical record was conducted at two urban training hospitals between April, 2001 and December, 2011. We divided included patients into two groups, which one with elevated Tn-I level ($Tn-I{\geq}0.1ng/dL$) and one without it, and compared the differences in initial vital signs, cardiac enzyme tests, an electrocardiogram, echocardiography, chest X-ray, and the clinical outcomes. Results: A total of 39 patients were included, out of them, 14 patients showed rise in Tn-I level. The length of hospital stay and ICU hospitalization was more prolonged in the patient group with elevated Tn-I level than non-elevated group. As well as the incidence of endotracheal intubation and abnormal findings in echocardiography or chest X-ray was higher in the Tn-I elevated group, which is statistically significant. Conclusion: The rising of serum Tn-I level in near-hanging patients were not uncommonly observed. We believe that the cardiac-related test including Tn-I is necessary for near-hanging patients, and those who are shown abnormal result in cardiac-related test may need close observation and intensive care.

Application and Validation of an Optimal Analytical Method using QuEChERS for the determination of Tolpyralate in Agricultural Products (QuEChERS법을 활용한 농산물 중 제초제 Tolpyralate의 최적 분석법 선발 및 검증)

  • Lee, Han Sol;Park, Ji-Su;Lee, Su Jung;Shin, Hye-Sun;Kim, Ji-Young;Yun, Sang Soon;Jung, Yong-hyun;Oh, Jae-Ho
    • Korean Journal of Environmental Agriculture
    • /
    • v.39 no.3
    • /
    • pp.246-252
    • /
    • 2020
  • BACKGROUND: Pesticides are broadly used to control weeds and pests, and the residues remaining in crops are managed in accordance with the MRLs (maximum residue limits). Therefore, an analytical method is required to quantify the residues, and we conducted a series of analyses to select and validate the quick and simple analytical method for tolpyralate in five agricultural products using QuEChERS (quick, easy, cheap, effective, rugged and safe) method and LC-MS/MS (liquid chromatography-tandem mass spectrometry). METHODS AND RESULTS: The agricultural samples were extracted with acetonitrile followed by addition of anhydrous magnesium sulfate, sodium chloride, disodium hydrogencitrate sesquihydrate and trisodium citrate dihydrate. After shaking and centrifugation, purification was performed with d-SPE (dispersive-solid phase extraction) sorbents. To validate the optimized method, its selectivity, linearity, LOD (limit of detection), LOQ (limit of quantitation), accuracy, repeatability, and reproducibility from the inter-laboratory analyses were considered. LOQ of the analytical method was 0.01 mg/kg at five agricultural products and the linearity of matrix-matched calibration were good at seven concentration levels, from 0.0025 to 0.25 mg/L (R2≥0.9980). Mean recoveries at three spiking levels (n=5) were in the range of 85.2~112.4% with associated relative standard deviation values less than 6.2%, and the coefficient of variation between the two laboratories was also below 13%. All optimized results were validated according to the criteria ranges requested in the Codex Alimentarius Commission (CAC) and Ministry of Food and Drug Safety (MFDS) guidelines. CONCLUSION: In conclusion, we suggest that the selected and validated method could serve as a basic data for detecting tolpyralate residue in imported and domestic agricultural products.

Fishing investigation of vertical bottom longline fisheries in sea mount of central northern Pacific (북태평양 중부 해산어장에 있어서 저층 선주낙의 어획실태)

  • Oh, Taeg-Yun;Kim, Yeong-Seung;Cho, Sam-Kwang;Kim, In-Ok;Choi, Seok-Gwan;Koh, Jeong-Rack;Yang, Won-Seok
    • Journal of the Korean Society of Fisheries and Ocean Technology
    • /
    • v.41 no.3
    • /
    • pp.188-198
    • /
    • 2005
  • This study was conducted to survey the catches of vertical bottom longline fisheries in the sea mount of central northern Pacific($30^{\circ}-42^{\circ}N$, $170^{\circ}-175^{\circ}E$), during the period of July 1 to August 25,2004 by commercial fishing vessel. The number of 57 test fishing was carried out in the central northern Pacific during 43 days and the total catches were 21,092.4kg as 19 fish species, CPUE/day and catches/day were 185 baskets and 490.5kg, respectively. Main fish species caught from the experimental fishing were Squalus mitsukurii (66.3%), Coelorhyrchus asperocephaius (11.7%) and Helicolenus avius (9.8%) and, average inside diameter for fish mouth was 4.0cm over. Catch ratio according to each fishing ground was the order of F, D, J, B and C. Catch ratio fur water depth was the order of 450-500m, 350-400m, 300-350m, 400-450m, 1000-1100m and 500-550m and, main species by water depth was Squalus mitsukurii for 300-400m, Etmopterus lucifer for 300-550m, Coelorhyrchus asperocephaius far 1,000m over. Catch ratio according to the kind of hooks was higher at the hook no.6 for Squalus mitsukurii and no. 5 for Etmopterus lucifer and, catch ratio by baits was higher at squid for Squalus mitsukurii, saury and eel for Helicolemus avius and saury for Etmopterus lucifer. Accordingly, it is thought that the extension of fishing hours is needed with the reduction of damage and loss for fishing gears during fishing operation.

Socio-economic Features of One Slice of Chicagoland Using A Geo-Spatial Information System (시카고 부분지역의 사회경제적 특성에 대한 지형공간정보체계의 이용)

  • Oh, Jong-Woo
    • Journal of Korean Society for Geospatial Information Science
    • /
    • v.1 no.2 s.2
    • /
    • pp.223-235
    • /
    • 1993
  • This study associates with socio-economic status in a slice section area of Chicago metropolitan to get spatial patterns of urban windows. GSIS(Geo-spatial Information System) has been monitored with several statistic methods, and geo-spatial map presentations. From the grouping analysis, the result displays that most suburban town have high income values, such as Elmhurst, Melrose Park, North Lake(Income ranges between $25,000${\sim}$30,000 : 1980 Sensus data). The factors produced form both analyses of SAS and BMDP are socio-ethnic, economic, hispanic, black, life expectancy, and multiple car ownership. In the study area the socio-ethnic factor is striking, and is composed of nine out of the fourteen varialbles. Geo-spatial 3-D mapping represents a socio-economic configuration of the study area. The high income value areas are Elmhurst and North Lack, and a spot between Belmont Ave. and the Lake Shore. Economic configuration is a vital importance of socio-economic activities in the urban areas. In the study area a minimum average income level is about $4,364 and maximun is $30,311.

  • PDF

Identification of Genes Modulated by High Extracellular Calcium in Coculture of Mouse Osteoblasts and Bone Marrow Cells by Oligo Chip Assay

  • Kim, Hyung-Keun;Song, Mi-Na;Jun, Ji-Hae;Woo, Kyung-Mi;Kim, Gwan-Shik;Baek, Jeong-Hwa
    • International Journal of Oral Biology
    • /
    • v.31 no.2
    • /
    • pp.53-65
    • /
    • 2006
  • Calcium concentration in the bone resorption lacunae is high and is in the mM concentration range. Both osteoblast and osteoclast have calcium sensing receptor in the cell surface, suggesting the regulatory role of high extracellular calcium in bone metabolism. In vitro, high extracellular calcium stimulated osteoclastogenesis in coculture of mouse osteoblasts and bone marrow cells. Therefore we examined the genes that were commonly regulated by both high extracellular calcium and $1,25(OH)_2vitaminD_3(VD3)$ by using mouse oligo 11 K gene chip. In the presence of 10 mM $[Ca^{2+}]e$ or 10 nM VD3, mouse calvarial osteoblasts and bone marrow cells were co-cultured for 4 days when tartrate resistant acid phosphatase-positive multinucleated cells start to appear. Of 11,000 genes examined, the genes commonly regulated both by high extracellular calcium and by VD3 were as follows; 1) the expression of genes which were osteoclast differentiation markers or were associated with osteoclastogenesis were up-regulated both by high extracellular calcium and by VD3; trap, mmp9, car2, ctsk, ckb, atp6b2, tm7sf4, rab7, 2) several chemokine and chemokine receptor genes such as sdf1, scya2, scyb5, scya6, scya8, scya9, and ccr1 were up-regulated both by high extracellular calcium and by VD3, 3) the genes such as mmp1b, mmp3 and c3 which possibly stimulate bone resorption by osteoclast, were commonly up-regulated, 4) the gene such as c1q and msr2 which were related with macrophage function, were commonly down-regulated, 5) the genes which possibly stimulate osteoblast differentiation and/or mineralization of extracellular matrix, were commonly down-regulated; slc8a1, admr, plod2, lox, fosb, 6) the genes which possibly suppress osteoblast differentiation and/or mineralization of extracellular matrix, were commonly up-regulated; s100a4, npr3, mme, 7) the genes such as calponin 1 and tgfbi which possibly suppress osteoblast differentiation and/or mineralization of extracellular matrix, were up-regulated by high extracellular calcium but were down-regulated by VD3. These results suggest that in coculture condition, both high extracellular calcium and VD3 commonly induce osteoclastogenesis but suppress osteoblast differentiation/mineralization by regulating the expression of related genes.