• Title/Summary/Keyword: 20c fashion

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Pharmacokinetic Study of YH1885 (I): Absorption, Distribution and Excretion of $^{14)C-YH1885$ in Rats (YH1885의 체내동태(제1보):흰쥐에서 $^{14)C-YH1885$의 단회투여시 흡수, 조직분포 및 배설)

  • Ahn, Byung-Nak;Fujio, Naoki;Kusumoto, Naotoshi;Abe, Yoshifumi;Odomi, Masaaki;Lee, Jong-Wook
    • YAKHAK HOEJI
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    • v.41 no.3
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    • pp.335-344
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    • 1997
  • The absorption, distribution and excretion of $^{14}C$ labeled YH1885 {5,6-Dimethyl-2(4-fluorophenylamino)-4-(1-methyl-1,2,3,4-tetrahydroisoquinolin-2-yl)pyrimidine hydroc hloride), a new proton pumpinhibitor, were investigated in rats after a single administration of $^{14}C$-YH1885. 1. After intravenous administration of 5mg/kg, the blood level of radioactivity declined in a biphasic fashion with the mean terminal elimination half-life of 12.4hr. 2. After oral administration of 20mg/kg, the maximum blood level of radioactirity was reached at 4.0hr in female rats. The blood level of radioactivity-time profiles in male and female rats were similar, and the absorptionof $^{14}C$-YH1885 was not affected by food. 3. Appproximately 89% and 1% of radioactivity of the total dose were excreted in feces and urine, respectively. 4. Biliary excretion of radioactivity was 47.9% of the dose. Enterohepatic circulation of radioactivity was 49.6%. 5. Radioactivity was excreted maily into feces via bile. 6. The concentration of radioactivity in most tissues reached the peak level at 4.0hr after dosing, and then declined. Autoradiograms of male rats showed that the radioactivity levlels in the fat, harder's gland, liver and G-Itract were higher than those in the other tissues and the elimination of radioactivity from fat and liver was slow. 7. Autoradiograms of a pregnant rat showed that radioactivity was transferred to mammary gland, placenta and fetus. The radioactivity level in the mammary gland was higher than that in the blood.

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A Study on the Fashion Accessary Product Development by Use of Korean Traditional Hanji (Part I) -Physical Properties of the Korean Traditional Paper(Hanji) Treated with Silcone resin- (전통한지를 활용한 패션 악세서리 상품개발 (제1보) -실리콘 수지로 처리된 한지의 물성변화-)

  • Kim Eun-Ah;Ryu Hyo-Seon;Kim Yong-Sook
    • Journal of the Korean Society of Clothing and Textiles
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    • v.30 no.3 s.151
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    • pp.481-486
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    • 2006
  • There are attempts to utilize Hanji for apparel material, but, the reason that the strength and durability of Hanji decrease to a great extent in the wet condition, restricts the usability of Hanji. In order to improve the resistance against water, Hanji was treated with silicone type water repellent agents. The treatment was carried out by conventional pad-dry-cure method. The optimum treatment condition was obtained by varying the concentration of repellent agent, curing temperature and time. Water repellency was tested by spray rating method. Wet and dry tensile strength, tearing resistance and abrasion resistance were examined after the treatment. Flexural stiffness and wrinkle recovery angles of hanji were also measured. In result, the optimum condition of treatment was at resin concentration of 40g/l, catalyst concentration of 20g/l(half of resin concentration), curing temperature of 160$^{circ}C$, curing time of 120 sec. Flexural stiffness of Hanji was hardly increased and wrinkle recovery angle of Hanji was improved a little by resin treatment. After the treatment, in dry condition, tensile strength and tearing resistance were little changed but abrasion resistance was improved. In wet condition, tensile strength, tearing strength and abrasion resistance were improved.

A Study on the Costume Culture of Xiongnu (흉노(匈奴)의 복식문화에 관한 연구)

  • Kim, Yong-Mun
    • Journal of the Korean Society of Costume
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    • v.63 no.3
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    • pp.1-16
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    • 2013
  • Xiognu people were the first of the Central-Asian nomads to establish a nation in 209 B.C. They always moved around looking for places to breed their animals and fertile grounds, so they wore clothes made of fur and leather and covered their tents with felt from the livestock. This research studies on the literatures, costumes and the achievement of archaeological excavation. Furthermore, to investigate on costumes excavated of Xiongnu, we visited the Mongolian National Museum and the Hermitage Museum. A corn-hat made of felt, a felt hat with ear flaps and a golden crown with a bird on the top were unearthed from a tomb of Xiongnu in Inner mongolia. Women usually wore pigtails, and men wore pigtails or ponytails but they cut their hair short when holding a funeral. Many pigtails discovered in Noyon uul tombs can be considered as their funeral customs. The Xiongnu wore a round or v-neck caftan attached straight sleeves reaching knees in the left folded style, and because they always rode horses, having the length of the caftan not go past their buttocks would have made it more convenient for them. During the period of Western Han, Ho refered to Xiongnu and it became a common name for northern races. They used leather belts and an animal-designed buckle was found. Women commonly rouged their cheeks for a vivid and cute look, and many ornaments were excavated including bracelets, rings and decorations made of gold, silver, copper and jade, among which there were hair ornaments used to identify one's class. A horse pattern with wings and a horn of Golmod T20 was substitution for the Schythian use of deer. Patterns or shape of unearthed articles present in the Xiongnu culture in Noyon uul had a close relationship with Altaic, Greek and Persian cultures. The Xiongnu clothing was made of animals' skin and fur, woolen textiles and felt. It was folded to the left for upper garments, and the pants were adjusted using a belt and shoes were made of leather, which was very suitable for protection against the cold and horse riding. Mobility played a significant role in their clothing.

Evaluation of Thermal Physiological Responses and Comfort in Vitamin E Fabric (비타민 E 소재의 인체생리반응 및 쾌적성 평가)

  • Im Soon;Chung Myung-Hee
    • The Research Journal of the Costume Culture
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    • v.13 no.3 s.56
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    • pp.406-413
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    • 2005
  • This study performed the evaluation of skin temperature, heart rate, temperature and relative humidity of microclimate, and subjective sensation, such as thermal sensation, wet sensation and comfort sensation to estimate physiological responses of the human body and its comfortable feeling to the vitamin E fabric. Experiments were performed on the five healthy adult women whose average age was 21, at climate chamber in which temperature, relative humidity and air current were set up below $30{\pm}\;1^{\circ}C$, $50{\pm}\;15\%$ and 0.2m/s, respectively. Two kinds of clothes were used for experiments: unfinished sports clothes, with the same form and the same size, of short-sleeved knit shirt and long trousers made with $100\%$ cotton, and finished sports clothes printed with the vitamin E solution of the level of $0.88\%$. Exercises of walking (about 105 steps/minute) with the exercise intensity of 2.5 were performed for 20 minutes using treadmill. In result, the study showed significant difference (p<0.01) in average skin temperature between unfinished and finished sport clothes, and represented higher value with having unfinished sport clothes in wear than with finished one. The study also showed significant difference (p<0.01) in heart rate only during the period of exercise, and represented higher value generally with unfinished sport clothes than with finished one. There were significant differences not only in temperature of microclimate (p<0.01) but also in humidity of microclimate (p<0.05) between two sport clothes. As for the evaluation of subjective sensation, the study showed significant difference (p<0.05) in thermal sensation between the two kinds of sport clothes, significant difference in wet sensation only during the period of exercise, and significant difference (p<0.05) in comfort sensation only during the period of recovery.

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One-Sided Nondestructive Evaluation of CFRP Composites By Using Ultrasonic Sound (초음파를 이용한 CFRP 복합재의 일방향 비파괴 평가)

  • Im, Kwang-Hee;Zhang, Gui-Lin;Choi, Sung-Rok;Ye, Chang-Hee;Ryu, Je-Sung;Lim, Soo-Hwan;Han, Min-Gui;Hsu, David K.
    • Journal of the Korean Society of Manufacturing Technology Engineers
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    • v.20 no.1
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    • pp.47-52
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    • 2011
  • It is well known that stiffness of composites depends on layup sequence of CFRP(carbon fiber reinforced plastics) laminates because the layup of composite laminates influences their properties. Ultrasonic NDE of composite laminates is often based on the backwall echoes of the sample. A pair of such transducers was mounted in a holder in a nose-to-nose fashion to be used as a scanning probe on composites. Miniature potted angle beam transducers were used (Rayleigh waves in steel) on solid laminates of composites. Experiments were performed to understand the behavior of the transducers and the nature of the waves generated in the composite (mode, wave speed, angle of refraction). C-scan images of flaws and impact damage were then produced by combining the pitch-catch probe with a portable manual scanner known as the Generic Scanner ("GenScan"). The pitch-catch signal was found to be more sensitive than normal incidence backwall echo of longitudinal wave to fiber orientation of the CFRP composites, including low level porosity, ply waviness, and cracks. Therefore, it is found that the experimentally Rayleigh wave variation of pitch-catch ultrasonic signal was consistent with numerical results and one-side ultrasonic measurement might be very useful to detect the defects.

Cryosurgery in the Treatment of Keloids (Cryosurgery를 이용(利用)한 Keloid의 치료(治療))

  • Jung, Young-Sik;Choi, See-Ho;Seul, Jung-Hyun;Lee, Tae-Sook
    • Journal of Yeungnam Medical Science
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    • v.2 no.1
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    • pp.23-30
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    • 1985
  • Keloids are abnormally healed skin wounds that develop in the subpapillary layer of the dermis. They are a lesion with wide, raised and deep scars. They exceed the original dimensions of the wound and grow mounds upon mounds of collagen in a pseudotumor fashion. Their treatment may take several forms such as surgery, intralesional injection of steroid, compression, superficial irradiation, and combination therapy. However, absolute method is nothing until now. Recently, the cryosurgery shows relatively good effect in treatment, so we tried the clinical experience with cryosurgery in the treatment of keloids. Material and methods: During the past 2 years, we treated 20 individuals of the keloids with severe itching and pain. The age ranged from 5 to 45 years old. Only 6 cases were biopsied before and after cryotherapy. The cryosurgery set we used was Toitu model CR 201 $N_2O$ gas (tip temperature is $-80^{\circ}C$) and was applied directly on the lesion about 4 to 5 minutes with slight compression. After cryosurgery in keloids, the following results were obtained: 1. It is both quick and easy method. 2. It causes little or no pain and no loss of blood. 3. Integumentary normalization is rapid. The new scar tissue is smaller, and more elastic and soft. 4. The pain, itching and paresthesia commonly associated with keloid is usually disappeared. 5. Other treatment can be used after cryosurgery. 6. Histologic picture after cryosurgery is similar with the result of steroid injection. 7. The mechanism of the cryosurgery in keloids is the result of the direct tissue destroying action and cryoimmunologic reaction.

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The Mechanical Properties of Thin Suede Fabric with Stretch Function (신축기능성 박지 Suede 직물의 역학적 성질 변화)

  • Park, Myung Soo
    • Textile Coloration and Finishing
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    • v.24 no.4
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    • pp.288-295
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    • 2012
  • Although some degree of mechanical properties of suede fabrics mainly related to non-woven suede fabric has some researched, the thin suede fabric has rarely been researched. In this study, polyester(DTY 50/72) was used for warp, and after producing latent yarn and sea-island yarn for weft, two yarns were compounded to produce sea-island DTY yarn. By using the two produced yarns for warp and weft, we produced thin suede fabric with stretch function. For weft 2ply, weft density 85, 90, 100(picks/in) were applied to weave fabric, and for weft 1ply, weft density 125, 135, 140(picks/in) were applied to produce weft face 5-end satin weave. The mechanical properties of the produced fabric were researched. The result are as followed. The weight loss ratio of the suede fabric produced for this experiment reached 15% on the conditions of temperature $90^{\circ}C$ and 20 minutes, so that island parts were completely separated. The strength of weft 1ply applied suede fabric was about 7.5kg and that of 2ply suede fabric and about 3.5kg. But the strain of two samples ranged from about 40 to 43%. Although Hari was high when weft was denser. The values of Koshi and Kisimi were low. And shear stiffness was high when sea-island DTY yarn was used. The WC value was higher in the case of 2ply than in that of 1ply sea-island DTY yarn for weft, so that we may conclude that Fukurami was more affected in the 2ply case.

Analyzing Learners Behavior and Resources Effectiveness in a Distance Learning Course: A Case Study of the Hellenic Open University

  • Alachiotis, Nikolaos S.;Stavropoulos, Elias C.;Verykios, Vassilios S.
    • Journal of Information Science Theory and Practice
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    • v.7 no.3
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    • pp.6-20
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    • 2019
  • Learning analytics, or educational data mining, is an emerging field that applies data mining methods and tools for the exploitation of data coming from educational environments. Learning management systems, like Moodle, offer large amounts of data concerning students' activity, performance, behavior, and interaction with their peers and their tutors. The analysis of these data can be elaborated to make decisions that will assist stakeholders (students, faculty, and administration) to elevate the learning process in higher education. In this work, the power of Excel is exploited to analyze data in Moodle, utilizing an e-learning course developed for enhancing the information computer technology skills of school teachers in primary and secondary education in Greece. Moodle log files are appropriately manipulated in order to trace daily and weekly activity of the learners concerning distribution of access to resources, forum participation, and quizzes and assignments submission. Learners' activity was visualized for every hour of the day and for every day of the week. The visualization of access to every activity or resource during the course is also obtained. In this fashion teachers can schedule online synchronous lectures or discussions more effectively in order to maximize the learners' participation. Results depict the interest of learners for each structural component, their dedication to the course, their participation in the fora, and how it affects the submission of quizzes and assignments. Instructional designers may take advice and redesign the course according to the popularity of the educational material and learners' dedication. Moreover, the final grade of the learners is predicted according to their previous grades using multiple linear regression and sensitivity analysis. These outcomes can be suitably exploited in order for instructors to improve the design of their courses, faculty to alter their educational methodology, and administration to make decisions that will improve the educational services provided.

Renal Effects of Intracerebroventricular Bromocriptine in the Rabbit (가토에 있어서 측뇌실내 Bromocriptine의 신장작용)

  • Kook, Young-Johng;Kim, Kyung-Keun;Kim, Jae-Pil;Kim, Kyung-Ho
    • The Korean Journal of Pharmacology
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    • v.21 no.1
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    • pp.49-61
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    • 1985
  • In view of the facts that dopamine (DA) when given directly into a lateral ventricle (i.c.v.) of the rabbit brain induces antidiuresis and that haloperidol, a non-specific antagonist of DA receptors, produces anti-diuresis in smaller doses and diuresis and natriuresis in larger doses, the present study was undertaken to delineate the roles of various DA receptors involved in the center-mediated regulation of renal function. Bromocriptine (BRC), a relatively specific agonist of D-2 receptors and at the same time a D-,1 antagonist, elicited natriuresis and diuresis when given i.c.v. in doses ranging from 20 to 600 {\mu}g/kg$, roughly in dose-related fashion, while the renal perfusion and glomerular filtration progressively decreased with doses, indicating that the diuretic, natriuretic action resides in the tubules, not related to the hemodynamic effects. These diuresis and natriuresis were most marked with 200 ${\mu}g/kg$, with the fractional sodium excretion reaching about 10%. With 600 ${\mu}g/kg$, however, the diuretic, natriuretic action was preceded by a transient oliguria resulting from severe reduction of renal perfusion, concomitant with marked but transient hypertension. When given intravenously, however, BRC produced antidiuresis and antinatriuresis along with decreases in renal hemodynamics associated with systemic hypotension, thus indicating that the renal effects produced by i.c.v. BRC is not caused by a direct renal effects of the agent which might have reached the systemic circulation. In experiments in which DA was given i.c.v. prior to BRC, 150 ${\mu}g/kg$ DA did not affect the effects of BRC (200 ${\mu}g/kg$), while 500 ${\mu}g/kg$ DA abolished the BRC effect. In rabbits treated with reserpine, 1 mg/kg i.v.,24 h prior to the experiment, i.c.v. BRC could unfold its renal effects not only undiminished but rather exaggerated and more promptly. In preparations in which one kidney is deprived of nervous connection, the denervated kidney responded with marked diuresis and natriuresis, whereas the innervated, control kidney exhibited antidiuresis. These observations suggest that i.c.v. BRC influences the renal function through release of some humoral natriuretic factor as well as by increasing sympathetic tone, and that various DA receptors might be involved with differential roles in the center-mediated regulation of the renal function.

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Consumer Intention to Purchase Domestic/Foreign Brand Jeans;Beliefs, Attitude, and Individual Characteristics. (국내 및 외국 상표 청바지의 구매의도에 따른 평가기준에 대한 신념과 추구이미지 및 의복태도의 차이연구)

  • 고애란
    • Journal of the Korean Society of Clothing and Textiles
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    • v.18 no.2
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    • pp.263-272
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    • 1994
  • The purpose of this study was to identify factors that might distinguish those who have a high level of Intention to purchase each of domestic, foreign designer and national brand jeans from those who have a low intention in terms of evaluative criteria belief, ideal jeans image and clothing altitude. The sample consisted of 198 male and 197 female students from five universities in Seoul. The questionnnaire consisted of 50 seven-point semantic differential scales dealing with evaluative criteria and ideal jeans image, beliefs about and intention to purchase domestic, foreign designer and foreign national brand jeans and 25 Likert type clothing attitude scales. Based on a series of t-tests the results showed that color and design were the most influencing factor among the evaluative criteria belief, regardless of brand type, while durability, accessory, sewing were the least. Sexy image, brand consciousnees and fashion interest were the important factor that distinguish high intention to purchase group fro)m low intention to purchase group.

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