• 대한한방소아과학회지
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• 제30권2호
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• pp.96-106
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• 2016

Objectives The purpose of this study is to investigate the effects of Gleditsiae Fructus 70% EtOH extract (JS_E) on anti-inflammatory action in HaCaT cells (A spontaneously immortalized human keratinocyte cell line) and inhibiting triglyceride genesis in SEB-1 cells (Immortalized human sebocyte). Methods The anti-inflammatory effect of JS_E was analyzed by enzyme-linked immunosorbent assays (ELISA) which measured levels of IP-10, RANTES and MDC in HaCaT cells. Also the effect on secretion of sebum of JS_E was analyzed by TG-S kit which measured the quantity of triglyceride in SEB-1 cells. Results JS_E inhibited IP-10, RANTES and MDC expression in a dose dependent manner. IP-10 expression was inhibited significantly in comparison to TNF-${\alpha}$ and IFN-${\gamma}$ recombination (TI) control group at concentration of JS_E $200{\mu}g/ml$ and RANTES and MDC expressions were inhibited significantly at concentration of JS_E 100, $200{\mu}g/ml$. JS_E also inhibited triglyceride secretion of SEB-1 cells significantly in comparison to the control group in a dose dependent manner. Conclusions This study shows that JS_E has the effects of anti-inflammatory action and inhibiting sebum secretion. According to these results, JS_E can be used for treating skin diseases such as acne and dermatitis caused by inflammation and excessive secretion of sebum by controlling the activity of the HaCaT and SEB-1 cells.

• 대한간호학회지
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• 제29권1호
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• pp.48-60
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• 1999

This study was done to determine the factors influencing smoking-cessation behavior in female university students. A total of 534 students participated in this cross sectional study by answering a questionnaire. The data collection was done between September 1 and October 31, 1997 The measurement tools used in this study were the self help change process scale (Cronbach's alpha＝.9930 : developed by Oh & Kim, 1996) for smoking-cessation behaviors, the self efficacy scale(Cronbach's alpha＝.8250 : developed by Sherer et al, 1982), the sex role acceptance scale (KR－20＝.7757 : developed by Kim, 1991) and the social support scale(Cronbach's alpha＝.9172 : developed by Park, 1985). The summarized results are follows : 1. The mean scores for smoking-cessation behaviors in smokers (N＝150) was 91.72 that was considered a middle score compared to the total possible score of measurement tool (150.0). The mean score for smoking-cessation behaviors by smoking-cessation step showed significant different between the groups(F＝11.71, p＝.000). 2. The group with no experience in smoking(N＝332) showed a high general self efficacy score (t＝5.24, p＝.000), and more openness to sex role acceptance(t＝-2.15, p＝.032) compared to the group with smoking experience (N＝202). 3. General self efficacy, sex role acceptance, and social support were not different significantly between the groups according to the steps in smoking-cessation. 4. Significant factors influencing smoking-cessation behavior (total, sub concepts) were religion, sex role acceptance, social support, smoking duration, smoking attitude, time of smoking onset, amount of smoking, drinking, and perception of health status. 5. Smoking-cessation behaviors which explained 11% of the variance were smoking attitude, and smoking duration. In conclusion, this study identified factors influencing smoking-cessation behavior. Thereby it will help in the development of smoking-cessation intervention strategies. For future research, exploration other determinants of smoking cessation behaviors, evaluation of intervention efficiency, and comparative study by gender characteristics are needed.

• 대한간호학회지
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• 제29권1호
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• pp.84-96
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• 1999

This study was conducted to identity the degree of burden and social support perceived by mothers of nephrotic syndrome patients. Also, relations between burden and social support were investigated to provide basis data for their family health and nursing intervention. The study subjects were mothers of nephrotic syndrome patients whose children were hospitalized in 2 Pediatric wards of University Hospital in Seoul and 1 in Pusan from Jun. 1, 1998 to Jun. 30, 1998. Burden measurement Instrument for this study was designed by the researcher and its basis in one developed by Montgomery et al.(1985) and the reliability was .78. Also. P.R.Q. Part I, II by Brandt and Weinert(1981) was used as social support measurement instrument and the reliability .71. The data analysis was done by SPSS, t-test, ANOVA Pearson correlation. The result were as follows. 1. Burden felt by mothers shows an average value of 60.82 (Maximum 86, Standard deviation 1.244). 2. Of the mother characteristics, the score of burden was high in case of no religion and low income. Of the patient characteristics, the score burden ranked as high MCNS, doing oral therapy, injection therapy at the same time and negative perceived patients condition. 3. The mean score of support was 77.54(Maximum 96, Standard deviation 1.096). 4. The main supporters were husband (the highest), brother, sister, health speciality and the subject expressed the highest satisfaction toward supporters in chronic disease. 5. Of the patient characteristics, the higher age group and the elder group showed high support. Also, positive perceived patient's condition, high support. 6. The relationship between burden and social support is not significant. In conclusion to the above study, the researcher suggests. 1. The Qualitative research to investigate influential factors on burden of family of nephrotic syndrome patients is needed.

• Journal of Species Research
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• 제2권1호
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• pp.15-54
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• 2013

Surveys on Jeju-do (Quelpart Isl.) unearthed about 40 earthworm species or sub-species. Several considered new to science are described. Only a dozen were previously known and these are taxonomically reviewed. The two most commonly recorded in surveys by S. Kobayashi in the 1930s were Drawida anchingiana Chen, 1933 and Metaphire quelparta (Kobayashi, 1937), neither recently relocated. Morphologically similar taxa, supported with DNA barcodes, for Moniligastridae, are Drawida anchingiana seogwipo, D. anchingiana halla and D. iucn spp. or sub-spp. nov. For Megascolecidae, new taxa and synonyms are: Amynthas arx and A. aucklandis spp. nov. that have seminal grooves rather than the eversible male pores of Metaphire plus Amynthas simplex is another new species. Amynthas sangumburi Hong & Kim, 2002 is recognized as a probable new synonym within the A. corticis (Kinberg, 1867) species-group while Amynthas corticis saeseum sub-sp nov. is described. Amynthas gracilis (Kinberg, 1867) is a new record from Jeju and Korea (with A. bouchei, A. omodeoi and A. edwardsi all by Zhao & Qiu, 2009 possible synonyms of this species group from China) with a Jejuan sub-species, A. gracilis insularum, sub-sp. nov. Presence on Jeju of Amynthas carnosus (Goto & Hatai, 1899) is confirmed (its further new synonyms are Chinese A. fuscus Qiu & Sun, 2012 and A. taiwumontis Shen et al., 2013), as is A. micronarius (Goto & Hatai, 1898) (with new synonym A. montanus Qiu & Sun, 2012 also an invalid secondary homonym). Amynthas phaselus maculosus (Hatai, 1930) is in new combination with A. kamitai (Kobayashi, 1934) and A. minjae Hong, 2001 syns. nov. Two newly described Metaphire quelparta sub-spp are M. q. seogwipo and M. q. valhalla these being supported with DNA barcodes despite the nominal taxon not yet being confirmed.

• 대한본초학회지
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• 제27권6호
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• pp.43-48
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• 2012

Objectives : This study was investigated to determine the contents of pesticide residues and sulfur dioxide residues in commercial herbal medicines in Korea. Methods : Chromatographic test was performed on 100 samples consisted with 10 kinds of medicinal plants including improted and domestic products. To establish 19 pesticide residues (DDE, DDD, DDT, Dieldrin, Methoxychlor, BHC isomers, Aldrin, Endosulfan isomers, Endrin, Captan, Procymidone, Chlorpyrifos and Imidacloprid) in commercial herbal medicines, chromatographic equipments were used with the gas chromatography-mass detector and gas chromatography-electron capture detector for qualitative analysis. The imidacloprid analysis was performed by high performance liquid chromatograpgy-ultraviolet detector at 270 nm UV wavelength. The contents of sulfur dioxides were analyzed by modified Monnier-Williams method. All methods were based on notification procedure of Korea Food & Drug Administration (KFDA). Results : The residual pesticides were not founded in improted and domestic samples. Among 100 samples, the residues of sulfur dioxide in 73 samples were not detected and 25 samples showed contents in the range of 0~21.90 mg/kg. The excess samples of MRLs were 2 samples (30 mg/kg to medicinal herbs), Asiasari Radix et Rhizoma (Imported product) and the average amount of sulfur dioxide in 2 unsuitable samples were 14.83 mg/kg. These samples were found to transgress KFDA regulatory guidance of residual sulfur dioxide. Conclusion : These results are able to use as basic data to improve the reliability and value of commercial medicinal herbs.

• 정보보호학회논문지
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• 제34권2호
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• pp.167-177
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• 2024

본 논문은 isogeny 기반 전자 서명 알고리즘인 SeaSign의 최적화 방안을 제안한다. SeaSign은 CSIDH의 class group action에 Fiat-Shamir with abort를 결합한 전자서명 알고리즘이다. CSIDH 기반 암호는 SIDH 기반 암호가 다항시간안에 공격됨에 따라 다시 주목받고 있지만, 이를 기반한 전자서명인 SeaSign은 비효율적인 속도로 많은 최적화가 진행되지 않았다. 본 논문에서는 SeaSign에 대한 효율적인 서명 방법을 제안한다. 제안하는 서명 방법은 간단하지만 강력하며, 알고리즘 내에서 rejection sampling의 위치 변경을 통해 이루어진다. 추가로, 본 논문에서는 제안하는 알고리즘이 최적 성능을 제공할 수 있는 파라미터를 제시한다. 제시한 결과, 기존 SeaSign의 파라미터를 사용할 경우, 본 논문에서 제안한 서명방법은 기존 SeaSign 대비 3배 빠른 성능을 보인다. 추가로 신규 제시된 파라미터와 본 논문의 서명 방법을 결합한 경우, 기존 SeaSign 대비 290배 빠른 성능과 Decru 등이 제안한 방법 대비 7.47배 빠른 성능을 제공한다.

• 농촌의학ㆍ지역보건
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• 제34권2호
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• pp.234-243
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• 2009

본 연구는 청소년 466명을 대상으로 2008년 5월부터 6월 까지 구조화된 설문지를 이용하여 정신건강실태를 파악하여, 청소년의 정신건강증진을 위한 기초 자료를 제공하는데 목적이 있다. 성별에서 평균 차이검증을 실시한 결과, 우울/불안, 사고의 문제, 주의집중 문제, 공격성, 내재화, 총 문제행동에서 여학생이 남학생보다 유의하게 더 높은 점수를 보였으며, 학년에 따라서는 총 사회능력에서 고등학생이 중학생보다 유의하게 더 낮은 점수를 보였다. 그리고 문제행동에서는 위축에서 고등학생이 중학생보다 유의하게 더 높은 점수를 보여주었고, 사고의 문제, 공격성에서는 중학생이 고등학생 보다 유의하게 더 높은 점수를 나타냈다. 그리고 임상군의 분포는 총 사회능력에서 32.6%, 총 문제행동에서 8.6%를 나타냈으며, 문제행동별 임상군의 분포 순위는 주의집중문제, 우울/불안, 공격성, 외현화 문제, 내현화문제, 사회적 미성숙 등의 순으로 나타났다. 그리고 성별에 따른 정상군과 임상군의 차이검증에서는 사회성, 우울/불안, 주의집중 문제, 내재화, 외현화에서 남학생보다 여학생이 더 많은 임상군의 분포를 보이며 유의한 차이를, 학년에 따른 정상군과 임상군의 차이검증에서는 학업수행에서 중학생보다 고등학생이 더 많은 임상분포를 보이며 유의한 차이를 나타냈다. 이상의 연구결과 일 지역사회 청소년 정신건강 실태는 남학생보다는 여학생이 그리고 고등학교 1학년 보다는 중학교 1학년이 더 많은 정신건강의 문제를 가지고 있는 결과를 보여주었다. 그러므로 여학생과 중학교 1학년을 대상으로 한 정신건강 증진 및 예방 접근이 무엇보다도 우선되어야한다. 또한 문제행동에서 많은 임상분포를 보인 주의집중, 우울/불안, 공격성 문제를 해결 하고 예방하기 위한 중재 프로그램 개발이 요구된다.

• 가정∙방문간호학회지
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• 제2권
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• pp.19-34
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• 1995

The purpose of this study was to analysis level on family caregiver's burden for the elderly with chronic disease in a rural area and to choose priority care group, thereby facilitating the development of interventions to reduce the caregiver's burden. For this purpose, data were collected by questionaire from June 10 to October 8, 1994. The instruments for data collection were Caregiver Burden Inventory by Novak(1989) and Zarit et al(1982), severity of dementia by Hughes Scales(1982), ADL by Lawton(1971), patients' family caregiving activity by pre-survey and reference review(Lee, 1993 ; Jang, 1990 ; Yoo, 1982). The subjects were 213 family caregiver of elderly with chronic disease in a rural area. The data was analysed by the use of t-test, ANOVA, correlation and multiple regression. The results were as follows ; 1. Total burden was evaluated below average, the mean of family burden was 46.98. By the diagnostic classification, Hypertension was 27.37, DM 32.46, CVA 62.96, Dementia 61.24. 2. Significant variables which were correlated to the family caregiver's burden were the patient's disease diagnosis (F=33.82, p<0.001), severity of dementia(F=30.52, p<0.001), the status of disease management(F=11.53, p<0.001), ADL(F=10.54, p<0.001), PADL(F=7.50, p<0.001), income(F=7.17, p<0.001), caregiver's health status(F=24.53, p<0.001), a view of patient's prognosis (F=22.17, p<0.001), relationship with the patient(F=33.82, p<0.001), the number of hours per day spent on caregiving(F=77.52, p<0.001), level of intimacy of caregiver and patients(F=8.75, p<0.001), level of helping(F=4.90, p<0.01), the frequency of caregiving activity(F=3.80, p<0.01), the number of admission(F=5.54, p<0.01), the length of caregiving(F=4.43, p<0.01), other chronic patient in family(t=2.81, p<0.01), caregiver's job(F=3.11, p<0.01), the duration of illness(F=2.98, p<0.05), caregiver's religion(F=2.93, p<0.05), medical security(F=3.89, p<0.05), caregiving's helper(t=2.42, p<0.05). 3. PADL was the most important predictor to family caregiver burden(R2=0.6611). In addition to this, IADL, caregiver's health status, the length of caregiving. level of intimacy of caregiver and patients, patient's age, the patient's disease diagnosis and patient's job accounted for 76% of family caregiver burden. 4. The criteria of priority care group were as follows ; the mean of family caregiver burden was above 58, above of moderate ADL, the number of hours per day spent on caregiving above of 8 hours, above of moderate dementia. By the diagnostic classification, number of priority care group, Hypertension was 4 (8.0%), DM 4(8.0%), CVA 34(64.1%), Dementia 45(75.0%).

• 한국과학교육학회지
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• 제22권1호
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• pp.12-21
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• 2002

이 연구의 목적은 정량적 현상제시와 정성적 현상제시를 하였을 때, 중학교 학생들의 갈등 정도를 알아보는 것이다. 연구 대상은 부산광역시 소재의 중학교 2학년 297명 을 대상으로 하였다. 검사 문항은 역학의 작용반작용 문항과 전기의 전구의 불의 밝기를 비교하는 문항을 사용하였고, 인지적 갈등을 측정하는 검사지는 권혁구(1999) 등이 개발한 도구를 사용하였다. 먼저, 정량적 현상제시 집단과 정성적 현상제시 집단의 인지갈등 점수를 비교해 보았다. 그리고 현상제시 후 자신의 선개념을 바꾼 학생들과 고수한 학생들의 갈등 점수를 비교해 보았다. 마지막으로, 선개념의 확신 정도와 갈등 정수와의 상관관계를 비교해보았다. 그 결과를 보면, 첫째, 선개념에서 오답을 선택한 학생들은 정성적 현상제시보다 정량적 현상제시에서 갈등 점수가 높게 나타났으며, 선개념에서 정답을 선택한 학생들은 정량적 현상제시보다 정성적 현상제시에서 갈등 점수가 높게 나타났다. 둘째, 자신의 선개념을 바꾼 학생들이 고수한 학생들에 비해 갈등 점수가 높게 나타났다. 마지막으로, 선개념의 확신정도와 갈등 점수와의 상관관계를 보면, 정량적 현상을 제시한 집단의 학생들 중 선개념에서 오답을 택한 학생들은 정적 상관을 보였고, 선개념에서 정답을 택한 학생들은 부적상관을 보였다. 정성적 집단은 뚜렷한 경향을 보이지 않았다.

• 한국산림과학회지
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• 제94권3호통권160호
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• pp.191-196
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• 2005

본 연구는 우리나라 소나무 90가계를 대상으로 오존에 대한 민감성을 비교하기 위하여 인공광형 생장상에서 100 ppb의 오존을 5개월간 처리하였다. 잎의 가시적 피해, 근원경 생장 및 개체건중량 등을 조사하였다. 잎의 가시적 피해는 내성그룹이 1.9%인 반면 민감성 그룹은 15.20%로 나타났다. 상대근원경 생장비는 내성그룹이 12% 생장한 반면, 민감성 그룹은 23%의 생장 감소를 보였다. 개체 건중량에서도 내성그룹은 17%의 증가를 보였으나 민감성 그룹에서는 33%의 감소를 보였다. 수체 부위별로는 뿌리부분이 가장 민감한 반응을 보였다. 모든 조사 요인을 표준화한 결과 강원 4, 16, 26, 27, 73호가 오존에 대한 내성 가계로 나타났고, 강원 40, 52, 83, 경기 1, 경북 20호 등이 민감한 가계로 나타났다. 이와 같이 가계수준에서 그룹간에 민감성의 차이로 보아 오존에 대한 유전적 변이를 확인 할 수 있었다. 이러한 연구결과로 오존에 대한 가시적 피해가 상대적으로 적고, 근원경 생장과 건중량의 감소율이 낮은 내성그룹이 확인되었다.