• Journal of dental hygiene science
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• v.10 no.5
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• pp.349-356
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• 2010

The purpose of this study was to examine the awareness of dental hygienists, who played a significant role in dental sector, about health care management and their needs for education in an attempt to pave the way for the development of a Dental Hygienist Coordination System(DHCS). The subjects were 156 dental hygienists at 85 dental clinics, who were selected in Gwangju based on the data released as of August 2008 by the Dental Association and public health centers in sampling region. A Questionnaire was conducted in person to gather survey data and SPSS 12.0 program was utilized to make a statistical analysis. This results findings suggested that a systematic curriculum should be developed by focusing on coordination theory and practice, counseling and educational practice, health insurance affairs and health insurance fee claim management.

• The Journal of The Korea Institute of Intelligent Transport Systems
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• v.16 no.6
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• pp.67-78
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• 2017

Traffic congestion cost is increasing annually. Specifically congestion caused by the CDB traffic contains more than a half of the total congestion cost. Recent advancement in the field of Big Data, AI paved the way to industry revolution 4.0. And, these new technologies creates tremendous changes in the traffic information dissemination. Eventually, accurate and timely traffic information will give a positive impact on decreasing traffic congestion cost. This study, therefore, focused on developing both recurrent and non-recurrent congestion prediction models on urban roads by adopting Recurrent Neural Network(RNN), a tribe in machine learning. Two hidden layers with scaled conjugate gradient backpropagation algorithm were selected, and tested. Result of the analysis driven the authors to 25 meaningful links out of 33 total links that have appropriate mean square errors. Authors concluded that RNN model is a feasible model to predict congestion.

• Journal of Ginseng Research
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• v.41 no.3
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• pp.247-256
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• 2017

Background: KG-135, a standardized formulation enriched with Rk1, Rg3, and Rg5 ginsenosides, has been shown to inhibit various types of cancer cells; however, the underlying mechanisms are not fully understood. In this study, we explored its effects in A549 human lung cancer cells to investigate the induction of Forkhead Class box O3a (FOXO3a) and autophagy. Methods: Cell viability was determined by sulforhodamine B staining. Apoptosis and cell cycle distribution were analyzed using flow cytometry. The changes of protein levels were determined using Western blot analysis. Autophagy induction was monitored by the formation of acidic vesicular organelles stained with acridine orange. Results: KG-135 effectively arrested the cells in G1 phase with limited apoptosis. Accordingly, a decrease of cyclin-dependent kinase-4, cyclin-dependent kinase-6, cyclin D1, and phospho-retinoblastoma protein, and an increase of p27 and p18 proteins were observed. Intriguingly, KG-135 increased the tumor suppressor FOXO3a and induced the accumulation of autophagy hallmark LC3-II and acidic vesicular organelles without an increase of the upstream marker Beclin-1. Unconventionally, the autophagy adaptor protein p62 (sequestosome 1) was increased rather than decreased. Blockade of autophagy by hydroxychloroquine dramatically potentiated KG-135-induced FOXO3a and its downstream (FasL) ligand accompanied by the cleavage of caspase-8. Meanwhile, the decrease of Bcl-2 and survivin, as well as the cleavage of caspase-9, were also drastically enhanced, resulting in massive apoptosis. Conclusion: Besides arresting the cells in G1 phase, KG-135 increased FOXO3a and induced an unconventional autophagy in A549 cells. Both the KG-135-activated extrinsic FOXO3a/FasL/caspase-8 and intrinsic caspase-9 apoptotic pathways were potentiated by blockade of autophagy. Combination of KG-135 and autophagy inhibitor may be a novel strategy as an integrative treatment for cancers.

• Korean Journal of Food Science and Technology
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• v.37 no.4
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• pp.513-518
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• 2005

Capillary electrophoresis (CE) method was developed to determine (+)-catechin and (-)-epicatechin contents in grape seed ethanol extract. CE separation was achieved using 100 mM phosphate and borate buffer at pH 6.0 as background electrolyte and fused silica capillary with 50 microns x 375 microns O.D. (effective length 20.0cm) maintained at $25^{\circ}C$. The applied voltage was 10kV, and detection was performed by DAD at 210 nm, Two catechins were well separated within 6 min with repeatability of <0.8% RSD for migration time and <2.0% RSD for peak area, and correlation coefficients higher than 0.994 were obtained from 58.0 to 174.0 mg/L with detection limit of 0.035 mg/L. Separated compounds were successfully determined. CE method was easy to handle and showed good reproducibility. CE method was compared with conventional coloring and HPLC methods, and main advantages of CE method were low amount of sample required, simple pre-sample treatment, good recovery rate, and short analysis time.

• Journal of Preventive Medicine and Public Health
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• v.30 no.2 s.57
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• pp.392-401
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• 1997

Generally working environment and worker's health status of small scale industries (SSI) which employ less than 50 workers are known to be poorer than those of large scale industries(LSI) which employ more than 500 workers. However, according to the analysis of occupational injuries in Korea, prevalence rate of occupational injuries of SSI was 3.1 times as high as LSI. But there was no difference in prevalence rate of occupational disease and werkers with suspected occupational disease(D1) between SSI and LSI. To confirm these two different facts, we surveyed working environment and worker's health status of SSI and LSI in Kyeungin industrial complex. Workers in SSI were 10,878 and workers in LSI were 8,291 and number of hazardous agents in SSI were 3,554 and those of LSI were 1,916. We found following results. First, proportion of male workers and workers who were less than 30 yens old and more than 50 yens old was higher in SSI compared to LSI. Second, worker in SSI had more liver disease, viral hepatitis, and pneumoconiosis than in LSI, and there were more worker with suspected occupational disease, general disease, and worker needed close observation in SSI. But these effects had not statistical significance under the condition controlled by age and sex with logistic regression. Third, the numbers measured for specific chemicals, organic solvents, and heavy metals in SSI was more than in LSI. However there was on difference in the excess rate of each hazardous agent between SSI and LSI. As the above results workers' health status in SSI was poorer than in LSI, but these results were mainly due to the population structure difference. Although there were some limitation of this study and problems of sensitivity and validity for periodic health examination and working environment evaluation method, the concept that working environment and worker's health status in SSI should be reviewed. In future the study that will reveal the real weak point of SSI should be performed.

• Journal of the Korea Concrete Institute
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• v.13 no.4
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• pp.314-320
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• 2001

In this paper, the properties of an expansive agent (CaO-CaS $O_4$) for dry shrinkage compensation were investigated by a series of experimental program, which might be used at On-Dol heating system as mortar type. The expansion principle of the CaO-CaS $O_4$ was mainly verified. As a result of this study, the correlation between the content of the expansive agent and the compressive strength was obtained in the form of exponential function(Y = A $e^{-x}$), showing that as the content of expansive agent increased as the expansion performance with the compressive strength increased by only a certain amount. Also, as a results of the analysis of a correlation between the expansive performance and the chemical properties which generally accompanied a part of quality management in manufacturing the expensive cement, the expansive performance was relative to only the contents of the F-CaO among chemical properties(Blaine, +44$\mu\textrm{m}$R, F-CaO, S $O_3$,L.O.I). And it was clarified that the results were relative to the second order function, showing that if the contents of the F-CaO increased the expansive performance Increased.d.

• Journal of the Korea Institute of Building Construction
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• v.18 no.1
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• pp.67-79
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• 2018

This paper provides theoretical deformation of lean concept and its application for usage of building information modeling (BIM) process. Recently, much research is focused on application of lean concept for more efficient usage of BIM. The lean theory and its basic function and feature is based on manufacturing industry. The manufacturing process can be improved by process re-engineering steps of lean concept which consist of the steps of value, value stream, flow, pull, perfection. However manufacturing process and construction process has different characteristics. Due to the differences, five steps of the traditional lean's process re-engineering can't be directly applied to the BIM based engineering process. In order to solve this problem, we conduct analysis on the characteristics of the manufacturing process and BIM based engineering. We propose modified and expanded concept of lean for process re-engineering and the modified theory was applied to the mechanical, electrical and plumbing (MEP) coordination process. Through the proposed 8 steps of methodology, 2D based process was changed to integrated and using BIM based MEP coordination process. In addition, the results showed the potentiality of cost reduction and process improvement. The results of this study can be a foundation for the theoretical combination of lean and a variety part of construction engineering process.

• The Korean Journal of Elementary Counseling
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• v.4 no.1
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• pp.263-284
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• 2005

The purpose of this study was to examine the effect of game-centered empathy training on the prosocial behaviors of elementary schoolers in a bid to suggest how their prosocial behaviors could be boosted. The research questions were posed as below: 1. Does game-based empathy training improve the overall empathy of school children? 2. Does game-based empathy training have a better effect on the cognitive empathy of school children or their emotional empathy? 3. Does game-based empathy training enhance the prosocial behaviors of school children? The subjects in this study were 62 children in their fourth year of D elementary school in Eumseong-gun, north Chungcheong province. They were divided into an experimental group and a control group, and a survey was conducted before and after the experimental group under-went empathy training for about six weeks. The instrument used in this study was David(1980)'s Interpersonal Reactivity Index adopted by Park Sung-hee(1996) to suit school children. Another instrument was Park Sung-hee (1997)'s inventory to assess the prosocial behaviors of children. The collected data were analyzed by SPSS 10.0 for Windows program, and reliability analysis and t-test were employed. The findings of the study were as follows: First, as for the effects of the game-based empathy training on the overall empathy of the elementary school youngsters that included both emotional and cognitive empathy, both groups got lower scores in posttest than in pretest. The experiment produced unexpected results, as the experimental group got significantly lower scores. This fact indicated that the game-based empathy training was ineffective. Second, the game-centered empathy training didn't exercise any influences on their cognitive and emotional empathy. The experiment had a reverse impact on the cognitive and emotional empathy of the experimental group, which implied that the training served as a factor to deteriorate the two types of empathy, and the hypothesis posed in this study was rejected. Therefore, which type of empathy could make a better progress by being exposed to the training couldn't definitely be determined. Third, the game-based empathy training didn't serve to Improve the prosocial behaviors of the elementary schoolers. There was no change in the experimental group, and this fact signified that there's something wrong with the attempt to develop school children's empathy to step up their prosocial behaviors. Based on the above-mentioned findings, the following conclusion was reached: First, the game-centered empathy training had no effects on boosting the overall empathy of the school children. Second, the game-centered empathy training couldn't be said to be effective in improving either cognitive empathy or emotional one. From a viewpoint of relativity, that could be said to affect emotional empathy more than cognitive one. Third, the game-based empathy training wasn't effective in improving prosocial behaviors. Rather, that resulted in interrupting the promotion of prosocial behaviors.

• Journal of Intelligence and Information Systems
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• v.15 no.2
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• pp.33-48
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• 2009

Capsule endoscopy is one of the most remarkable inventions in last ten years. Causing less pain for patients, diagnosis for entire digestive system has been considered as a most convenience method over a normal endoscope. However, it is known that the diagnosis process typically requires very long inspection time for clinical experts because of considerably many duplicate images of same areas in human digestive system due to uncontrollable movement of a capsule endoscope. In this paper, we propose a method for clinical diagnosticians to get highly valuable information from capsule-endoscopy video. Our software system consists of three global maps, such as movement map, characteristic map, and brightness map, in temporal domain for entire sequence of the input video. The movement map can be used for effectively removing duplicated adjacent images. The characteristic and brightness maps provide frame content analyses that can be quickly used for segmenting regions or locating some features(such as blood) in the stream. Our experiments show the results of four patients having different health conditions. The result maps clearly capture the movements and characteristics from the image frames. Our method may help the diagnosticians quickly search the locations of lesion, bleeding, or some other interesting areas.

• Journal of Microbiology and Biotechnology
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• v.16 no.10
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• pp.1554-1560
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• 2006

A Gram-positive, aerobic or facultative anaerobic, non motile, endospore-forming bacterial strain, designated Gsoil $114^T$, was isolated from a soil sample of a ginseng field in Pocheon Province (South Korea), and was characterized taxonomically by using a polyphasic approach. It grew well on nutrient agar medium and utilized a limited number of organic substrates as sole carbon sources, including D-xylose and some other carbohydrates, but did not utilize L-amino acids and organic acids. The isolate was positive for oxidase test but negative for catalase, and negative for degradation of macromolecules such as starch, cellulose, xylan, casein, chitin, and DNA. The G+C content of the genomic DNA was 41.8 mol%. The predominant isoprenoid quinone was menaquinone 7 (MK-7). The major fatty acids were $anteiso-C_{15:0}$ (32.1%), $iso-C_{15:0}$ (30.5%), and $anteiso-C_{17:0}$ (30.2%). Comparative 16S rRNA gene sequence analysis showed that strain Gsoil $114^T$ fell within the radiation of the cluster comprising Bacillus species and joined Bacillus shackletonii LMG $18435^T$ with a bootstrap value of 95%. The highest 16S rRNA gene sequence similarities were found with Bacillus shackletonii LMG $18435^T$ (97.6%), Bacillus acidicola DSM $14745^T$ (96.9%), Bacillus sporothermodurans DSM $10599^T$ (96.5%), and Bacillus oleronius DSM $9356^T$ (96.5%). The phylogenetic distance from any other validly described species within the genus Bacillus was less than 96%. DNA-DNA hybridization experiments showed that the DNA-similarities between strain Gsoil $114^T$ and closest phylogenetic neighbors were less than 39%. On the basis of its phenotypic properties and phylogenetic distinctiveness, strain Gsoil $114^T$ (=KCTC $13944^T$=DSMZ $18134^T$) was classified in the genus Bacillus as the type strain of a novel species, for which the name Bacillus ginsengihumi sp. nov. is proposed.