• Polymer(Korea)
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• v.31 no.5
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• pp.447-453
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• 2007

In this study, we fabricated recrystallized PLGA (rPLGA) particles using the vacuum drying method. In order to investigate an applicability of the rPLGA particles for controlled release system of 5-fluorouracil (5-FU) loaded PLGA wafer, we prepared three different wafers using; 1) untreated PLGA (uPLGA), 2) rPLGA, and 3) uPLGA and rPLGA (4 : 1, 1 : 1 or 1 : 4). The rPLGA particles were characterized using NMR, IR and GPC to compare with uPLGA particles. The surface and cross section morphology of the prepared wafers were observed by the scanning electron microscope. The release profile of the 5-FU loaded wafer was measured by HPLC. The 5-FU/rPLGA wafer released the incorporated 5-FU in a sustained manner with low initial burst compared to 5-FU/uPLGA. These results showed that the ratio of pure PLGA/recrystallized PLGA can affect the release behaviors.

• Journal of Sasang Constitutional Medicine
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• v.19 no.2
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• pp.22-29
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• 2007

1. Objectives Sasang Contitutional Medicine, a part of the traditional Korean medical lore, treats illness through a constitutional typing system that categorizespeople into four constitutional types. A few of the important criteria for differentiating the constitutional types are external appearances, inner state of mind, and pathological patterns. We had been developing a 3D Automatic Face Recognition Apparatus (3D-AFRA) in order to evaluate the external appearances with more objectivity. This apparatus provides a 3D image and numerical data on facial configuration, and this study aims to evaluate the mechanical accuracy of the 3D-AFRA hardware. 2. Methods Several objects of different shapes (cube, cylinder, cone, pyramid) were each scanned 10 times using the 3D Automatic Face Recognition Apparatus (3D-AFRA). The results were then compared and analyzed with data retrieved through a laser scanner known for its high accuracy. The error rates were analyzed for each grid point of facial contour scanned with Rapidform2006 (Rapidform2006 is a 3D scanning software that collects grid point data for contours of various products and products and product parts through 3D scanners and other 3D measuring devices; the grid point data thusly acquired is then used to reconstruct highly precise polygon and curvature models). 3. Results and Conclusions The average error rate was 0.22mm for the cube, 0.22mm for the cylinder, 0.125mm for the cone, and 0.172mm for the pyramid. The visual data comparing error rates for measurement figures retrieved with Rapidform2006 is shown in $Fig.3{\sim}Fig.6$. Blue tendency indicates smaller error rates, while red indicates greater error rates The protruding corners of the cube display red, indicating greater error rates. The cylinder shows greater error rates on the edges. The pyramid displays greater error rates on the base surface and around the vertex. The cone also shows greater error around the protruding edge.

• Journal of dental hygiene science
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• v.8 no.4
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• pp.337-345
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• 2008

The purpose of this study was to investigate factors affecting dental hygienists's stress in order to provide dental hygienists's stress management methods. The results of this study were as follows. 1. A sample of 168 dental hygienists were selected to participate in this study. The participate of 66.1% was under 25 old years and 87.5% was unmarried. A majority of he dental hygienists's job place was clinical areas 86.9% and working experience was 1~4 years (47.6%). A average dental hygienists's salary was 1,000,000~1,500,000 won/month (63.7%). A average dental hygienists's working time was under 8 hours/day (57.1%). 5days/week (58.3%) was working and the participate of 78.0% was working on night-time. 2. Dental hygienists's stress under 25 years old was higher than over 26 years old (p < 0.05). It was found that dental hygienists was significantly related to stress from less income (p < 0.05), longer working time (p < 0.01). In job demand areas, Night-time workers (p < 0.05) and 5days/week (p < 0.05) worker was more stress than others participates. In job autonomy areas, longer working experience in present dental clinical(p < 0.01) and higher salary/ month (p < 0.01) were more stress. The job instability of unmarried dental hygienists were more stress than married subjects. In stress of organization system, longer working time/day (p < 0.05), under 25 years old (p < 0.01), high salary (p < 0.05), 5day/week (p < 0.05) dental hygienists's stress was higher than others.

• Clean Technology
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• v.24 no.2
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• pp.146-153
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• 2018

The water footprint is an important component of the Single Market for Green Product initiative based on the EU's Roadmap to a Resource Efficient Europe. In July 2014, the EU has established the International Standard for Water Footprint (ISO 14046) and Korea has complied with the Korean Industrial Standard (KS I ISO 14046) in April 2015. If a certification system based on the international standard (ISO 14046) is introduced, developing countries such as India and Vietnam, which are not equipped with bases, can become a trade barriers in exporting, so Korea should establish a strategy to reverse them. On the other hand, water footprints are designed to take into account local environmental impacts when compared to similar footprints (eg, carbon footprint) using LCA, so that products manufactured and manufactured in Korea will have an impact on domestic waters Should be considered. Therefore, the method of the water footprint should conform to the standard for compatibility with other countries. In order to consider the domestic water condition, it is necessary to identify suitable indicator or factor for estimating water footprint on Korea. For this purpose, this study analyzed the water footprint estimation study conducted at domestic and foreign based on international standards and through the analysis of statistical data related to domestic water resources, we confirmed the applicability of the water footprint methodology in Korea.

• Proceedings of the Korean Vacuum Society Conference
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• 2011.08a
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• pp.293-294
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• 2011

It is known that semiconductor quantum-dot (QD) heterostructures have superior zero-dimensional quantum confinement, and they have been successfully applied to semiconductor laser diodes (QDLDs) for optical communication and infrared photodetectors (QDIPs) for thermal images [1]. The self-assembled QDs are normally formed at Stranski-Krastanov (S-K) growth mode utilizing the accumulated strain due to lattice-mismatch existing at heterointerfaces between QDs and cap layers. In order to increase the areal density and the number of stacks of QDs, recently, sub-monolayer (SML)-thick QDs (SQDs) with reduced strain were tried by equivalent thicknesses thinner than a wetting layer (WL) existing in conventional QDs (CQDs) by S-K mode. Despite that it is very different from CQDs with a well-defined WL, the SQD structure has been successfully applied to QDIP[2]. In this study, optical characteristics are investigated by using photoluminescence (PL) spectra taken from self-assembled InAs/GaAs QDs whose coverage are changing from submonolayer to a few monolayers. The QD structures were grown by using molecular beam epitaxy (MBE) on semi-insulating GaAs (100) substrates, and formed at a substrate temperature of 480$^{\circ}C$ followed by covering GaAs cap layer at 590$^{\circ}C$. We prepared six 10-period-stacked QD samples with different InAs coverages and thicknesses of GaAs spacer layers. In the QD coverage below WL thickness (~1.7 ML), the majority of SQDs with no WL coexisted with a small amount of CQDs with a WL, and multi-peak spectra changed to a single peak profile. A transition from SQDs to CQDs was found before and after a WL formation, and the sublevel of SQDs peaking at (1.32${\pm}$0.1) eV was much closer to the GaAs bandedge than that of CQDs (~1.2 eV). These revealed that QDs with no WL could be formed by near-ML coverage in InAs/GaAs system, and single-mode SQDs could be achieved by 1.5 ML just below WL that a strain field was entirely uniform.

• The Journal of the Petrological Society of Korea
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• v.8 no.3
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• pp.171-182
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• 1999

The Myeonbongsan caldera, 10.2X8.0 km, developed within older sequences of sedimentary formations and intermediate composition volcanis in the southern Cheongsong area. Volcanic rocks in the caldera block include lower intermediate volcanics, middle tuffaceous sequences and upper silicic ones. The silicic volcanics, which is named Myeonbongsan Tuff, are composed of crystal-rich ash-flow tuff(300 m) , bedded tuff(30 m) and pumice-rich ash-flow tuff(700 m) in ascending order. Several intrusions dominate the early sequences within the caldera. The caldera collapsed in a trapdoor type when silicic ash-flow tuffs erupted fro major vent area in the caldera. Normal faulting along a ring fault system except the southwestern part dropped the tuffs down to the northrase with a maximum displacement of about 820 m. The Myeonbongsan Tuff is just about 1,030 m thick inside the northeastern caldera, with its base not exposed, and southwestward thinning down. Rhyolitic plug and ring dikes are emplaced along the central vent and the caldera margins, and the ring dikes are cut by plutonic stocks in the southeastern and northwestern parts. The caldera volcanism eviscerated the magma chamber by a series of explosive eruptions during which silicic magma was erupted to form the Myeonbongsan Tuff. Following the last ash-flow eruption, collapse of the chamber roof resulted in the formation of the Myeonbongsan caldera, a subcircular trapdoor-type depression subsiding about 820 m deep. After the collapse, stony to flow-banded rhyolites were emplaced as circular plugs and ring dikes along the central vent and the caldera margins respectively. Finally after the intrusions, another plutons were emplaced as stocks outside the caldera.

• Proceedings of the Korean Vacuum Society Conference
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• 2013.02a
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• pp.108-109
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• 2013

Mitochondria play key roles in the production of cell's energy. Their dominant function is the synthesis of adenosine 5'-triphosphate (ATP) from adenosine diphosphate (ADP) and phosphate (Pi) through the oxidative phosphorylation. Evaluation of drug-induced mitochondrial toxicity has become increasingly important since mitochondrial dysfunction has recently been implicated in numerous diseases including cancer and diabetes mellitus. Mitochondrial functions have been monitored via oxygen consumption, mitochondrial membrane potential, and more importantly via ATP synthesis since ATP synthesis is the most essential function of mitochondria. Various analytical methods have been employed to investigate ATP synthesis in mitochondria, including high performance liquid chromatography (HPLC), bioluminescence technique, and pH measurement. However, most of these methods are based on destructive analysis or indirect monitoring through the enzymatic reaction. Infrared absorption spectroscopy (IRAS) is one of the useful techniques for real-time, label-free, and direct monitoring of biological reactions [1,2]. However, the strong water absorption requires very short path length in the order of several micrometers. Transmission measurements with thin path length are not suitable for mitochondrial assays because solution handlings necessary for evaluating mitochondrial toxicity, such as rapid mixing of drugs and oxygen supply, are difficult in such a narrow space. On the other hand, IRAS in the multiple internal reflection (MIR) geometry provides an ideal optical configuration to combine solution handling and aqueous-phase measurement. We have recently reportedon a real-time monitoring of drug-induced necrotic and apoptotic cell death using MIR-IRAS [3,4]. Clear discrimination between viable and damaged cells has been demonstrated, showing a promise as a label-free and real-time detection for cell-based assays. In the present study, we have applied our MIR-IRAS system to mitochondria-based assays by monitoring ATP synthesis in isolated mitochondria from rat livers. Mitochondrial ATP synthesis and hydrolysis were in situ monitored with MIR-IRAS, while dissolved oxygen level and solution pH were simultaneously monitored with O2 and pH electrodes, respectively. It is demonstrated that ATP synthesis and hydrolysis can be monitored by the IR spectral changes in phosphate groups in adenine nucleotides and MIR-IRAS is useful for evaluating time-dependent drug effects of mitochondrial toxicants.

• Fire Science and Engineering
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• v.32 no.1
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• pp.81-88
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• 2018

Air and ultra lightweight aerogels were used to lighten the weight of the firefighters' protective clothing. In order to lighten the firefighters' protective clothing composed of 3 layers (outer shell, mid-layer, lining), it was most effective to replace the lining which occupied the largest weight in the total weight with the new materials. Thermal protective performance tests were carried out on flame (ASTM D 4108), radiant heat (KS K ISO 6942) and mixing heat (KS K ISO 17492) of flame and radiation. When the lining felt was replaced with an air layer, the air layer must be at least 3 mm to meet the KFI and ISO standards for the thermal protective performance. However, even if the thickness of the air layer increased to 10 mm, the thermal protective performance was lower than that of the existing products. When the felt was replaced with aerogels, the TPP rating (ASTM D 4108) satisfied the KFI standard at the 2 mm thickness of the aerogels. When the thickness of the aerogels was 3 mm, the TPP rating was improved about 140% compared to the existing products. It was confirmed that not only weight reduction but also thermal protective performance was improved by use of aerogels. However, due to the fragile nature of aerogels, a method of fixing them to a constant thickness between layers constituting a firefighters' protective clothing should be considered in the future.

• Journal of Wetlands Research
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• v.22 no.4
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• pp.295-301
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• 2020

This research analyzed the relationship between environmental factors and the density of Sycios angulatus in the Miho Stream, Geum River water system in order to secure basic data for the control of the ecosystem-distrubing plant Sycios angulatus. As a result of the soil particle size analysis of Sycios angulatus habitat, it was found that the density of Sycios angulatus decreased as the silty and clay contents increased. Most of the Sycios angulatus habitats had high sandy and silt content, and low clay content of less than 2%. The increased flow rate reduced the density of Sicyos angulatus. This is because when the flow rate is increased, the Sicyos angulatus cannot grow due to the change in soil characteristics. Water quality plays a role in supplying nutrients when Sicyos angulatus are submerged. However, due to the change in soil characteristics during flooding, the density of Sicyos angulatus tended to decrease due to impaired growth. The Sicyos angulatus can be managed through artificial and natural techniques. The appropriate natural control technique is the creation of a natural waterway in the habitats to change the water contents.

• Proceedings of the Korean Institute Of Construction Engineering and Management
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• 2008.11a
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• pp.572-577
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• 2008

In order to apply strategic advanced project management to the Korean construction industry, the study conducted a comparative analysis of the project management body of knowledge of the advanced countries such as the USA and Japan as well as Europe. As a result, it was found that the connection to 'execution' of 'strategy' was highlighted as a common main issue in the theoretical background of project management body of knowledge, and strategic planning, which aligns 'program management' based on the integration of multiple project management and operations in single project with 'portfolio management' for selection and concentration, has been emphasized. Accordingly, the study built up the framework for the application of strategic advanced project management for strategic action in the Korean construction industry and proposed the following applicable solutions for implementation into the current Korean construction industry: 1) Innovate global competitiveness by preparing an 'ideology and philosophy' for the strategic action of an organization, 2) Establish a strategic 'environment' in consideration of the culture and structure of an organization, 3) Propose a strategic 'vision' for attaining a realizable goal within an organization, 4) Create an 'investment' on the portfolio in line with the strategy, 5) 'Execute' the program through the portfolio and project management. Lastly, the study brought up strategies for sustainable growth by applying strategic advanced project management to the Korean construction industry with a view to acquiring 'Performance' through the implementation and operation of their integrated system.