• Biomedical Science Letters
• /
• v.20 no.2
• /
• pp.56-61
• /
• 2014

This study attempted to confirm the antioxidative potential of luteolin against tert-butyl hydroperoxide (t-BHP) induced oxidative damage and to investigate its molecular mechanism related to glutathione (GSH)-dependent enzymes in HepG2 cells. Treatment with luteolin resulted in attenuation of t-BHP induced generation of reactive oxygen species (ROS) and oxidative stress-mediated cell death. In addition, accelerated expression of GSH-dependent antioxidative enzymes, glutathione peroxidase (GPx) and glutathione reductase (GR), and heme oxygenase (HO)-1, as well as strengthened GSH content was induced by treatment with luteolin, which was in accordance with increased nuclear translocation of nuclear factor-erythroid 2 p45-related factor 2 (Nrf2), a transcription factor for phase 2 enzymes, in a dose-dependent manner. These results suggest that the cytoprotective potential of luteolin against oxidative damage can be attributed to fortified GSH-mediated antioxidative pathway and HO-1 expression through regulation of Nrf2 in HepG2 cells.

• Fashion & Textile Research Journal
• /
• v.12 no.5
• /
• pp.626-632
• /
• 2010

The results of the image evaluations by various shapes of skirts which are typical female's lower garment were as follows; 1. The composition factors of images by the shapes of skirts were classified into five factors. The 1st factor is lovely image factor, the 2nd is attractive image factor, the 3rd is practical image factor, the 4th is slim-looking image factor and the 5th is long-looking image factor. 2. In the 1st factor- lovely image factor, tiered skirt, $360^{\circ}$ flared skirt and $180^{\circ}$ flared skirt were evaluated to express lovely images. In the 2nd factor- attractive image factor, $180^{\circ}$ flared skirt was evaluated to express refine and attractive images. In the 3rd factor- practical image factor, $360^{\circ}$ flared skirt and gathered skirt were evaluated to express easy and practical images. In the 4th factor- slim looking image factor, males evaluated 8gored skirt and females evaluated gathered skirt to express fat images. In the 5th factor- long looking image, $180^{\circ}$ flared skirt was evaluated to express long looking images by both sexes. 3. In the lovely image factor, gathered skirt was evaluated most differently between the sexes. Both in the attractive and practical image factor, tiered skirt was evaluated most differently between the sexes. 4. In the preference of male and female university students according to the shapes of skirts, both the sexes prefered flared skirt. But the low prefered shapes of skirts were differently evaluated between the sexes; the male students' was A-lined skirt and the female's was pleated skirt and wrap skirt.

• Journal of Korean Society for Atmospheric Environment
• /
• v.27 no.1
• /
• pp.41-49
• /
• 2011

The power plants are one of the GHG major source among the sectors of fossil fuel combustion, therefore information of its emission factors is very essential to the establishing control strategies for the greenhouse gas emissions. The $CH_4$ and $N_2O$ concentration from power plants were measured using GC-FID and GC-ECD. The results showed that $CH_4$ emission factor was 0.33 kg/TJ and $N_2O$ emission factor was 0.88 kg/TJ. The $CH_4$ and $N_2O$ emission factors developed in this study were compared with those for IPCC default value and other countries emission factors. The results showed that $CH_4$ emission factor was lower than IPCC default value and Finnish emission factor, but higher than Japanese emission factor. $N_2O$ emission factor was higher Japanese emission factor and IPCC default emission factor however lower than Finnish emission factor. More research is needed on our own emission factors of various energy-consuming facilities in order to stand on a higher position in international negotiations regarding the treaties on climate changes.

• The Research Journal of the Costume Culture
• /
• v.9 no.2
• /
• pp.319-332
• /
• 2001

This study attempts to measure body sizes and somatotypes of 844 female middle and high students girls in their growth period and to investigate characteristics of each of the measured somatotypes. The data used for this study were 50 items of body sizes obtained from anthropometric measurements. The purposes of the study are as follows: 1. to analyze physical characteristics according to age. 2. to extract factors of somatotypes using factor analyses. 3. to classify somatotypes according to physical characteristics using cluster analyses. The study results were as follows: 1. TH anthropometric measurements indicated that three existed collective patterns of somatotypes across Group I(12∼13 years old), Group II(14∼15 years old), and Group III(16∼18 years old). 2. Through factor analyses, 6 factors were yielded from each age group. The cumulative proportions of these factors were 77% for Group I, 75% for Group II, and 72% for Group III. Factor I indicates a horizontal size factor and Factor 2 indicates a vertical size factor. 3. Group I and Group II ere classified into 5 types and Group III was classified as 3 types. In Group I, middle height and a little slim types were most prevalent(28%). In Group II, low height and very slim types were most prevalent(28.9%). Finally, In Group III, low height and slim types were most prevalent(4.6%)

• Journal of Environmental Science International
• /
• v.14 no.2
• /
• pp.251-258
• /
• 2005

Statistical analysis between operating parameters and effluent quality on advanced wastewater treatment plant was performed. Through factor analysis four factors derived varimax rotation were selected each plant. Four components explained $80\%,\;82\%$ of the total variance of the process, respectively. The components on MLE plant were identified in the following order: 1) HRT increase and BOD load decrease by influent decrease, 2) Biomass, 3) SVI increase by internal return increase, 4) Microbial diversity by SRT increase. On $A_2O$ plant, we defined them as follows: factor 1, high MLSS by return rate increase, HRT increase by influent decrease; factor 2, biomass; factor 3, BOD of influent; factor 4 was relate to DO.

• The Journal of the Korea Contents Association
• /
• v.15 no.4
• /
• pp.490-499
• /
• 2015

In this study, for the introduction factors of ERP system suggested in the prior study, I analyzed the importance of each introduction factor by using Delphi methodology and AHP. As a result of analysing the importance of the introduction factors of the 1st layer, the supplier factor was analyzed to be the most important factor among innovation factor, information technology factor, the user factor, the supplier factor, and in the weight analysis on the 2nd layer considering the importance of 1st layer, the standard work model of the supplier factor was a suitable factor, and the CEO participation factor(.086) was analyzed as the second most important introduction factor. These analysis results enable to determine that domestic Small & Medium enterprises' position hope to introduce by selecting a system in which the company characteristics and management strategies are applied well, because they should operate an ERP system that has already been developed, and in this course, the participation of CEO was also found to be a very important factor.

• Journal of Environmental Science International
• /
• v.17 no.3
• /
• pp.315-323
• /
• 2008

Based on the result of extraction of common factors executed in order to elucidate the visual attributes of street scenery by types through the rotation of 23 adjective variables by Varimax, the visual attributes expressed after the construction of the facilities using street scenery were anylized to be 4 factors including factor 1 through factor 4. Theexplanation of the 4 factor groups to explain the entire distribution was 65.3% and these factor groups are the psychological attributes felt when using facilities are constructed by securing the street spaces in downtowns and the factors were named as naturalness(factor 1), locality(factor 2), identity(factor 3) and clarity(factor 4) respectively. Based on the result of one-way layout distribution analysis, the preferences for street scenery by types were found out to show considerable differences at 1 % significance level. Based on the result of multiple regression analysis, all of the factors explaining preferences including factor 1 through factor 4 were significant at 1 % significance level. In case other conditions are constant, if the values of the adjective variables related to locality(factor 2) increase by 1 unit, the preferences which are the values of dependent variables will increase by 0.709. The variable with the largest relative contribution among the 4 factor groups was the locality(factor 2) factor group and on the contrary, it was found that the independent variable with least influences was the clarity(factor 4) factor group.

• Journal of Korean Society for Atmospheric Environment
• /
• v.28 no.4
• /
• pp.423-434
• /
• 2012

This study was carried out to develop for the emission factor of greenhouse gas (GHG) from medium and smallscaled incineration facility using RPF which is considering as a part of renewable energy in UNFCC. The actual concentration of the exhaust gas and the fuel composition of RPF were measured for the calculation of GHG emission factor in RPF incinerators, and were compared with the IPCC guideline. The $CO_2$ and $N_2O$ emission factors by the actual concentration of exhaust gas were $2.3575{\pm}1.0070tCO_2/tRPF$ and $0.0014{\pm}0.0014tN_2O/tRPF$ respectively. Also, $CO_2$ emission factor by the RPF composition was $2.7057{\pm}0.0540tCO_2/tRPF$. The GHG emission factor per energy by the actual concentration was $83.0867{\pm}26.0346tCO_2e/TJ$ which showed higher consistency with the GHG emission factor ($80.3967tCO_2e/TJ$) of waste plastic in the IPCC guideline (2006b). The $CO_2$ and $N_2O$ emission factor calculated in this study is considered as a meaningful data for GHG emission factor of RPF incineration facility because of not being developed in ROK.

• The Korean Journal of Physiology and Pharmacology
• /
• v.26 no.6
• /
• pp.469-478
• /
• 2022

WNT signaling plays an important role in cardiac development, but abnormal activity is often associated with cardiac hypertrophy, myocardial infarction, remodeling, and heart failure. The effect of WNT signaling on regulation of atrial natriuretic peptide (ANP) secretion is unclear. Therefore, the purpose of this study was to investigate the effect of Wnt agonist 1 (Wnta1) on ANP secretion and mechanical dynamics in beating rat atria. Wnta1 treatment significantly increased atrial ANP secretion and pulse pressure; these effects were blocked by U73122, an antagonist of phospholipase C. U73122 also abolished the effects of Wnta1-mediated upregulation of protein kinase C (PKC) β and γ expression, and the PKC antagonist Go 6983 eliminated Wnta1-induced secretion of ANP. In addition, Wnta1 upregulated levels of phospho-transforming growth factor-β activated kinase 1 (p-TAK1), TAK1 banding 1 (TAB1) and phospho-activating transcription factor 2 (p-ATF2); these effects were blocked by both U73122 and Go 6983. Wnta1-induced ATF2 was abrogated by inhibition of TAK1. Furthermore, Wnta1 upregulated the expression of T cell factor (TCF) 3, TCF4, and lymphoid enhancer factor 1 (LEF1), and these effects were blocked by U73122 and Go 6983. Tak1 inhibition abolished the Wnta1-induced expression of TCF3, TCF4, and LEF1 and Wnta1-mediated ANP secretion and changes in mechanical dynamics. These results suggest that Wnta1 increased the secretion of ANP and mechanical dynamics in beating rat atria by activation of PKC-TAK1-ATF2-TCF3/LEF1 and TCF4/LEF1 signaling mainly via the WNT/Ca²⁺ pathway. It is also suggested that WNT-ANP signaling is implicated in cardiac physiology and pathophysiology.

• Biomedical Science Letters
• /
• v.22 no.1
• /
• pp.1-8
• /
• 2016

Several studies have investigated the various effects of dexamethasone (Dex) on the proliferation and differentiation of mesenchymal stem cells (MSCs). Previously, we reported that co-treatment with L-ascorbic acid 2-phosphate and fibroblast growth factor (FGF)-2 maintained differentiation potential in MSCs through expression of hepatocyte growth factor (HGF). In this study, we investigated the effects of co-treatment with FGF-2 and Dex on the proliferation and differentiation potential of MSCs during a 2-month culture period. Co-treatment with FGF-2 and Dex increased approximately a 4.7-fold higher accumulation rate of MSC numbers than that by FGF-2 single treatment during a 2-month culture period. Interestingly, co-treatment with FGF-2 and Dex increased expression of HGF and maintained adipogenic differentiation potential during this culture period. These results suggest that co-treatment with FGF-2 and Dex preserves the proliferation and differentiation potential during long-term culture.