• The Plant Pathology Journal
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• v.19 no.5
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• pp.266-268
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• 2003

In 2002, sooty mold was observed on persimmon (Diopyros kald) from the Jinju Agricultural Products Wholesale Market in Gyeongnam, Korea. The lesion of the sooty mold usually appeared as scars or wounds formed on the surface of the fruits. The symptom started with water soaking lesion, then the fruit softened rapidly. Colony of the causal pathogenic fungus was dark green in color on potato dextrose agar. The diameter of growing hyphae was 1-2 $\mu\textrm{m}$. The mostly one-celled conidia were ovoid, lemon or cylinder in shape, blastophores, and sized 46-132 $\mu\textrm{m}$. Erected conidiophores were long-branched chains and their lengths varied from 24 to 346 $\mu\textrm{m}$ with 2-5 $\mu\textrm{m}$ width. The optimum temperature for mycelial growth was about 2$0^{\circ}C$. Based on their mycological characteristics, the fungus was identified as Cladosporium cladosporioides. This is the first report in Korea of the sooty mold of persimmon caused by the said fungus.

• Korean Journal of Medicinal Crop Science
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• v.24 no.1
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• pp.7-13
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• 2016

Background : Ginger has been extensively used in foods and traditional medicines in Asian countries. Despite its frequent consumption in daily life, the mechanism of potential interactions between ginger components-drug has not been examined. To elucidate the mechanism of governing the effects of 6-shogaol, a primary constituent of dried ginger, on human cytochrome P450 (CYP) isoenzymes an incubation studies were carried out using pooled human liver microsome (HLM). Methods and Results : CYP isoenzyme specific substrate was incubated with multiple concentrations of inhibitor, HLM and cofactors. 6-shogaol showed a potent inhibitory effect on CYP2C9, CYP1A2 and CYP2C19 with half maximal inhibitory concentration ($IC_{50}$) values of 29.20, 20.68 and $18.78{\mu}M$ respectively. To estimate the value of the inhibition constant ($K_i$) and the mode of inhibition, an incubation study with varying concentrations of each CYP isoenzyme-specific probe was performed. 6-shogaol inhibited CYP2C9 and CYP2C19 noncompetitively ($K_i=29.02$ and $19.26{\mu}M$ respectively), in contrast, the inhibition of CYP1A2 was best explained by competitive inhibition ($K_i=6.33{\mu}M$). Conclusions : These findings suggest that 6-shogaol may possess inhibitory effects on metabolic activities mediated by CYP1A2, CYP2C9 and CYP2C19 in humans.

• Journal of Microbiology and Biotechnology
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• v.24 no.6
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• pp.765-770
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• 2014

This study aimed to characterize CTX-M producers of urinary E. coli and K. pneumoniae isolates and to determine the prevalence of plasmid-mediated antimicrobial resistance genes among them. Minimum inhibitory concentrations (MICs) were determined, and PCR and sequencing were performed. Among the 42 (82.3%) E. coli and 24 (77.4%) K. pneumoniae isolates containing $bla_{CTX-M}$, $bla_{CTX-M-14}$ and $bla_{CTX-M-15}$ were detected in 23 and 19 E. coli isolates, respectively, and in 7 and 17 K. pneumoniae isolates, respectively. CTX-M producers of urinary E. coli and K. pneumoniae were resistant to multiple antibiotics and contained other antimicrobial resistance genes. CTX-M-15 producers contained more antimicrobial resistance genes than did CTX-M-14 producers.

• The Korean Journal of Food And Nutrition
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• v.24 no.1
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• pp.124-131
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• 2011

We analyzed content and peptides in order to investigate the productivity from Cheonggookjang(fast-fermented soybean paste), fermenting it for 180 hours at $40^{\circ}C$. Results showed that pH was 7.07 at the start and became 7.41 in 24 hours, it eventually increased to 8.63 after 180 hours. Acidity was 0.2 in 12 hours, 0.5 in 12 hours, and then remained on 0.1 thereafter. Total sugar was 1.54 mg/$m\ell$ at the start, but it gradually decreased to 0.76 mg/$m\ell$ after the lapse of 48 hours, and 1.0 mg/$m\ell$ in 120 hours, and finally 0.8 mg/$m\ell$ in 180 hours. Reducing sugar was 0.14 mg/$m\ell$ at the start, and 0.88 mg/$m\ell$ after the lapse of 24 hours, 0.64 mg/$m\ell$ in 48 hours, 0.26 mg/$m\ell$ in 72 hours, and showed no definite change untill 180 hours. The amount of free amino acid was $0.19\;{\mu}M/\ell$ at the start, and $4.88\;{\mu}M/\ell$ after the lapse of 72 hours, $4.5\;{\mu}M/\ell$ in 120 hours, and then it rapidly decreased to $0.23\;{\mu}M/\ell$ after180 hours. Absorbance of soluble protein and peptide at 280 nm was 12.4 in 48 hours, 31.12 in 120 hours, and 31.12 in 180 hours. HPLC revealed that in the fermentation process, large molecular proteins are hydrolyzed into small peptides and amino acids, and after the lapse of 48 hours the pattern became almost the same. The protease activity of Cheonggookjang was 0.011 unit/$m\ell$ after the lapse of 36 hours and then it decreased. The result shows as Cheonggookjang started its deamination of amino acid in 100 hours, it is desirable to produce peptide within 100 hours of its fermentation.

• The Korea Journal of Herbology
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• v.38 no.6
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• pp.45-52
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• 2023

Objectives : Effects of baicalein (BA) on oxidative stress in RAW 264.7 mouse macrophages stimulated with peptidoglycan (PG) and lipopolysaccharide (LPS) were investigated. Methods : RAW 264.7 co-stimulated with LPS and PG were incubated with BA at concentrations of 25 and 50 µM. Incubation time was 18 h, 20 h, 22 h, 24 h, and 26 h. After incubation, the production of hydrogen peroxide in RAW 264.7 was measured with dihydrorhodamine 123 assay. Additionally, RAW 264.7 stimulated with PG were incubated with BA at concentrations of 25 and 50 µM for 24 h. After incubation, NO production was evaluated by griess reagent assay. Results : BA significantly inhibited hydrogen peroxide productions (p <0.05). In details, production of hydrogen peroxide in 'LPS and PG'-stimulated RAW 264.7 treated for 18 h with BA at concentrations of 25 and 50 µM was 91.27% and 89.22% of the control group treated with LPS and PG only, respectively; the production of hydrogen peroxide for 20 h was 92.19% and 90.58%, respectively; production of hydrogen peroxide for 22 h was 91.69% and 89.89%, respectively; production of hydrogen peroxide for 24 h was 92.4% and 90.19%, respectively; production of hydrogen peroxide for 26 h was 91.7% and 89.04%, respectively. Additionally, BA at the concentration of 50 and 100 µM significantly inhibited NO production in PG-induced RAW 264.7 (p <0.05). Conclusions : BA might have anti-oxidative activity related to its inhibition of hydrogen peroxide production in 'LPS and PG'-stimulated RAW 264.7 macrophages.

• Proceedings of the KSEEG Conference
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• 2003.04a
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• pp.131-134
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• 2003

계기지진기록에 의하면, 한반도에서는 중국이나 일본만큼 지진발생빈도가 높거나 강진은 없으나, 북한에서는 추가령단층대 이서지역, 남한에서는 아산만～영일만 일원을 따라 대상으로 분포한다. 역사지진기록에 의하면, 경주시 주변에서 8개의 큰 지진이 일어났으며, 이중 779년에 일어난 경주지진에서는 백명 이상의 사상자가 발생한 기록이 있다고 하였다(경재복, 1997). (중략)

• Korean Journal of Food Science and Technology
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• v.14 no.3
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• pp.271-275
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• 1982

Low-temperature in-bin drying with high-moisture paddy were demonstrated and studied under local autumn weather condition. Paddy with the initial moisture content of about 24.5 percent in the steel storage bin(diameter: 3 m, height: 3.17 m) was uniformly dried to about 15 percent by continuous blowing of ambient air (average temperature: $10.5^{\circ}C$, RH: 58 percent) in the middle part of October. The amount of grain and grain height were 4.19 M/T and 90 cm, respectively. Total fan operation time was 288 hours and airflow rate was $4.81\;m^3/min/m^3$ of paddy. Mean drying rate was 0.03 percent per hour and enery requirement for fan operation was 0.38 KWh per kg water removed.

• Journal of the Korea Institute of Information Security & Cryptology
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• v.18 no.3
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• pp.9-21
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• 2008

In this paper, we revisit a generally accepted opinion: implementing Elliptic Curve Cryptosystem (ECC) over GF$(2^m)$ on sensor motes using small word size is not appropriate because partial XOR multiplication over GF$(2^m)$ is not efficiently supported by current low-powered microprocessors. Although there are some implementations over GF$(2^m)$ on sensor motes, their performances are not satisfactory enough due to the redundant memory accesses that result in inefficient field multiplication and reduction. Therefore, we propose some techniques for reducing unnecessary memory access instructions. With the proposed strategies, the running time of field multiplication and reduction over GF$(2^{163})$ can be decreased by 21.1% and 24.7%, respectively. These savings noticeably decrease execution times spent in Elliptic Curve Digital Signature Algorithm (ECDSA) operations (Signing and verification) by around $15{\sim}19%$.

• International Journal of Computer Science & Network Security
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• v.24 no.1
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• pp.119-126
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• 2024

Disease caused by the coronavirus (COVID-19) is sweeping the globe. There are numerous methods for identifying this disease using a chest imaging. Computerized Tomography (CT) chest scans are used in this study to detect COVID-19 disease using a pretrain Convolutional Neural Network (CNN) ResNet50. This model is based on image dataset taken from two hospitals and used to identify Covid-19 illnesses. The pre-train CNN (ResNet50) architecture was used for feature extraction, and then fully connected layers were used for classification, yielding 97%, 96%, 96%, 96% for accuracy, precision, recall, and F1-score, respectively. When combining the feature extraction techniques with the Back Propagation Neural Network (BPNN), it produced accuracy, precision, recall, and F1-scores of 92.5%, 83%, 92%, and 87.3%. In our suggested approach, we use a preprocessing phase to improve accuracy. The image was enhanced using the Contrast Limited Adaptive Histogram Equalization (CLAHE) algorithm, which was followed by cropping the image before feature extraction with ResNet50. Finally, a fully connected layer was added for classification, with results of 99.1%, 98.7%, 99%, 98.8% in terms of accuracy, precision, recall, and F1-score.

• Journal of the Korean Magnetics Society
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• v.19 no.1
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• pp.12-16
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• 2009

Z-type barium ferrite [($Ba_{3}Co_{0.8}Zn_{1.2}Fe_{24}O_{41}$, $Ba_{3+{\delta}}Co_{0.8}Zn_{1.2}Fe_{24}O_{41}$ ${\delta}$ = 3, 5, 7, 13 wt%. $Ba_{3}Co_{0.8}Zn_{1.2}Fe_{24+{\delta}}O_{41}$ ${\delta}$ = 5, 7, 10 wt% )] were synthesized using co-precipitation method. The microstructure and magnetic properties of synthesized particles were investigated. In all prepared particles M-type Ba ferrite is identified with Z-type Ba ferrite together. It is found that particles having 7 wt% for Ba and 5 wt% for Fe excess addition revealed high saturation magnetization, respectively. All synthesized particles showed relatively high coercivity for device application. This result may be attributed to the contribution of M-type Ba ferrite. Ba and Fe excess addition was not affected to the structural change of CoZnZ Ba ferrite. The certain amount of excess additions of Ba and Fe and the 2 step heat-treatment may be beneficial to the improvement of soft magnetic properties of Z-type barium hexa-ferrite