• Korean Journal of Exercise Nutrition
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• v.24 no.1
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• pp.24-28
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• 2020

[Purpose] Recent studies have demonstrated a probable association between ACE I/D polymorphism and obesity. Thus, this study aimed to investigate whether ACE I/D polymorphism influenced the susceptibly of developing obesity in Korean adults. [Methods] A total of 353 healthy Korean adults aged between 30 and 82 years were recruited, including 157 males and 196 females. Among the participants, 103 (29.2 %) were classified as normal (BMI < 23 kg/m²), 117 (33.1 %) as overweight (23 kg/m² ≤ BMI < 25 kg/m²), and 133 (37.7 %) as obese (BMI ≥ 25 kg/m²). ACE polymorphism (rs1799752) analysis was performed using the MGB TaqMan® SNP Genotyping assay with 3 types of primers and 2 types of probes. The distributions of the ACE genotypes and allele frequencies were analyzed among the three groups using the Hardy-Weinberg equilibrium, chi-square tests, and multiple regression analysis. [Results] The distribution of the ACE genotypes were as follows: normal [II: n=38 (36.9 %), ID: n=46 (36.8 %), DD: n=19 (18.4 %)], overweight [II: n=43 (36.8 %), ID: n=55 (47.0 %), DD: n=19 (16.2 %)], and obese [II: n=41 (30.8 %), ID: n=76 (57.0 %), DD: n=16 (12.0 %)]. Unexpectedly, the I allele, rather than the D allele, was common in the obese group. [Conclusion] ACE I/D polymorphism is not associated with BMI in Korean adults. Thus, it is unlikely to be a powerful candidate gene for obesity in Korean adults.

• Journal of Korean Medicine for Obesity Research
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• v.24 no.1
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• pp.102-110
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• 2024

This study reports the clinical effects of Korean medicine treatments, herbal medicine, modified fasting, and space spinal conduction exercise and manipulation (SSCEM) on adolescent obesity patient. A 16-year-old male with a body mass index (BMI) 35.5 kg/m² was diagnosed with class III obesity. We prescribed herbal medicine and modified fasting alternately three times over a period of five months. Additionally, Korean medicine treatments and SSCEM were performed during the treatment period. After treatment, there was a decrease in body weight by 19.86%, from 115.8 kg to 92.8 kg, BMI from 35.5 kg/m² to 28.6 kg/m², and body fat mass from 38.1 kg to 17.0 kg. The results of this study showed that Korean medicine treatments, herbal medicine, modified fasting, and SSCEM could be useful in influencing changes in body composition among obese adolescents.

• Journal of the Korean Institute of Gas
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• v.18 no.6
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• pp.1-6
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• 2014

This study is based on a investigation regarding the evaporation rate of a volatile liquid(methanol, tetrahydrofuran, xylene) according to changes of the temperature and wind. The weight of a volatile liquid was standardized to 24 g and the mixture was formed with the same weight ratio. In order to discover about the effect of the wind velocity, small fan was installed at 10 cm above the entrance and 30 cm away in the direction of the cylinder. The effect of the wind velocity was tested at 0 m/s, 1.63 m/s, 2.03 m/s respectively and the effect of the temperature on the volatile liquid was experimented at the temperature of $21^{\circ}C$, $32^{\circ}C$, $52^{\circ}C$ in the constant temperature water base. As a result, in case of Xylene, the evaporation rate of the tetrahydrofuran and methanol showed 1.4 mg/min, 19.8 mg/min and 10.2 mg/min respectively. Also, the effect of the evaporation rate on the temperature of the volatile liquid and on the velocity of wind was shown to be very sensitive. At the same time, the evaporation rate of the mixture showed large difference compared to that of the single volatile liquid.

• Electrical & Electronic Materials
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• v.24 no.5
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• pp.12-19
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• 2011

• Computational Structural Engineering
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• v.23 no.1
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• pp.19-24
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• 2010

• Journal of Astronomy and Space Sciences
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• v.26 no.4
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• pp.421-424
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• 2009

The $JHK_S$ magnitudes of the red giant branch tip (TRGB) and the distance moduli of the nearby dwarf irregular galaxy IC 1613 have been determined from the near-infrared luminosity functions (LFs) of the resolved stars in the galaxy. Applying a Savitzky-Golay filtering, we derived the second derivatives of the LFs, and estimated the apparent magnitudes of the TRGB as $m_J\;=\;19.1$, $m_H\;=\;18.4$, and $m_{Ks}\;=\;18.0$. The mean values of the theoretical absolute magnitudes of the TRGB were measured by using the Yonsei-Yale isochrones with a metallicity range of -2.1 < [Fe/H] < -0.5 and age of 12 Gyr. The derived values of near-infrared TRGB distance moduli for IC 1613 are (m - M) = $24.12{\pm}0.25$, $24.20{\pm}0.44$, and $24.00{\pm}0.52$ for J, H, and $K_S$ bands, respectively.

• Korean Journal of Clinical Pharmacy
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• v.29 no.2
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• pp.101-108
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• 2019

Background: High doses of methotrexate (MTX) are often used in various chemotherapy protocols to treat acute lymphoblastic leukemia (ALL) and non-Hodgkin's lymphoma (NHL) in children, but its delayed elimination increases the occurrence of adverse events, such as bone marrow suppression. The aim of this study was to investigate the elimination of MTX at 24 and 48 hours. Methods: We retrospectively analyzed electronic medical records of ALL or NHL pediatric patients who received $5g/m^2$ MTX infusion over 24 hours (between June, 2012 and July, 2018) at the Yonsei University Health System, Korea. The delayed elimination of MTX concentrations was assessed with 100 or $150{\mu}M$ MTX at 24 hours, and 2 or $5{\mu}M$ at 48 hours. Results: Among the 85 MTX cycles administered, 23 cycles were classified in delayed elimination group, and 62 cycles showed normal elimination. At 24 hours, the delayed elimination group with MTX concentration > $100{\mu}M$ showed higher percentage than group with MTX concentration < $100{\mu}M$ (45.8% vs. 19.7%, p = 0.015). However, no differences were observed at $150{\mu}M$ MTX (p = 0.66). At 48 hours, the delayed elimination was higher than the normal elimination at both concentration baselines (p < 0.001 at $2{\mu}M$, p = 0.024 at $5{\mu}M$). Conclusions: MTX concentrations greater than $100{\mu}M$ show high probability of delayed elimination at 24 hours. When MTX levels are above normal, leucovorin and hydration regimens should be continued to prevent delayed elimination.

• Korean Journal of Organic Agriculture
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• v.24 no.4
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• pp.833-847
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• 2016

Drought stress is a major agricultural limitation to crop productivity worldwide, especially by which leafy vegetables, plant leaves eaten as vegetable, could be more lethal. The study was carried out to know the effect of drought tolerance plant growth promoting bacteria (PGPB) on water stress of kale seedlings. A total of 146 morphologically distinct bacterial colonies were isolated from bulk soil and rhizosphere soil of leafy vegetables and screened for plant growth promoting microbioassay in greenhouse. Out of them the isolate SB19 significantly promoted the growth of kale seedlings in increasement of about 42% of plant height (14.1 cm), 148% of leaf area ($19.0cm^2$) and 138% of shoot fresh weight (1662.5 mg) attained by the bacterially treated plants compared to distilled water treated control (9.9 cm, $7.7cm^2$, 698.8 mg). Shoot water content of SB19 treated kale seedlings (1393.8 mg) was also increased about 152% compared with control (552.5 mg). The SB19 isolated from bulk soil of kale plant in Iksan, Korea, was identified as species of Bacillus based on 16S rRNA gene sequencing analysis. We evaluated the effect of drought tolerance by the Bacillus sp. SB19 on kale seedlings at 7th and 14th days following the onset of the water stress and watering was only at 7th day in the middle of test. In the survey of 7th and 14th day, there were mitigation effect of drought stress in kale seedlings treated with $10^6$ and $10^7cell\;mL^{-1}$ of SB19 compared to distilled water treated control. Especially, there were more effective mitigation of drought damage in kale seedlings treated with $10^7cell\;mL^{-1}$ than $10^6cell\;mL^{-1}$. Further, although drought injury of bacterially treated kale seedlings were not improved at 14th day compared with 7th day, drought injury of $10^7cell\;mL^{-1}$ of SB19 treated kale seedlings were not happen rapidly but developed over a longer period of time than $10^6cell\;mL^{-1}$ of SB19 or control. The diffidence of results might be caused by the concentration of bacterial suspension. This study suggests that beneficial plant-microbe interaction could be a important role of enhancement of water availability and also provide a good method for improving quality of leafy vegetables under water stress conditions.

• Journal of the Korean Ceramic Society
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• v.24 no.6
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• pp.553-560
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• 1987

Amorphous ferrites with composition B2O3-mBaO-nFe2O3 were prepared by an ultra rapidquenching technique. X-ray patterns and SEM reveal the products to be amrophous at room temperature. BaFe12O19 fine particles extracted from amorphous Ba-ferrites which additived Al2O3, SiO2, TiO2 and CoO have narrow size distribution, average 0.2$\mu\textrm{m}$, and coercive force, average 1400 Oe, increased with increasing TiO2 amounts. The obtained BeFe12O19 fine particles would be appreciated as perpendicular magnetic recording media.

• Proceedings of the KIEE Conference
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• 2001.11a
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• pp.78-80
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• 2001

DC accelerating aging characteristics of praseodymium-based ZnO varistors doped with $Dy_2O_3$ were investigated with sintering time. The varistor sintered for 1h exhibited the highest nonlinearity, with a nonlinear exponent of 66.61 and a leakage current of $1.16{\mu}A$, whereas they did not exhibit relatively high stability. The varistor sintered for 2h having nonlinear exponent of 54.81 and leakage current of $2.52{\mu}A$ showed very excellent stability, which the variation rates of varistor voltage, nonlinear exponent, and leakage current are -1.19%, -4.00%, and +75.79% for 2h, under DC accelerated aging stress, such as ($0.85\;V_{1mA}/115^{\circ}C$/24h)+($0.90\;V_{1mA}/120^{\circ}C$/24h)+($0.95\;V_{1mA}/125^{\circ}C$/24h)+($0.95\;V_{1mA}/150^{\circ}C$/24h).