• 제목/요약/키워드: 17B

검색결과 6,635건 처리시간 0.032초

천식(喘息)의 침구치료(鍼灸治療)에 관(關)한 문헌적(文獻的) 고찰(考察) (Clinical study of Acupuncture effect on Chronic Headache)

  • 이성환;김창환;이윤호
    • Journal of Acupuncture Research
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    • 제17권3호
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    • pp.36-44
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    • 2000
  • The purpose of this study is to arrange the acupuncture therapy on the asthma from the oriental medical literature. The results obtained as follows. 1. The cause of the asthma is the intrinsic factors and the over-sensitive reactions. The decreased function of the lung and the kidney are chronically affected to the asthma. 2. The typical sign of the asthma is tachypnea and wheezes to be heard throughout the lung field, particularly during expiration. 3. Bladder meridian, Conception vessel, and Lung meridian used frequently for the acupuncture therapy, and Bladder meridian, Conception vessel, Stomach meridian, and Lung meridian used frequently for the moxibusrion on the asthma. The acupuncture points of Lung meridian used most frequently on the asthma, but the acupuncture points of Heart meridian have not used. 4. Acupuncture point at B13, CV22, LI4, CV12, CV17, 536, B12 used used frequently for the acupuncture therapy, and the acupuncture point at B13, CV22, B12, CV17, B43 used frequently for the moxibustion on the asthma Particularly B13 and CV22 used most frequently for the acupuncture therapy on the asthma.

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절단된 홍수 자료에 대한 확률가중적률 추정량 (Expected Probability Weighted Moment Estimator for Censored Flood Data)

  • 전종준;김영오;김용대;박준형
    • 한국수자원학회:학술대회논문집
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    • 한국수자원학회 2010년도 학술발표회
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    • pp.357-361
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    • 2010
  • 미래의 연별 최대 강수량 예측의 정확성을 향상시키는데 역사적 자료가 도움이 된다는 많은 연구 결과가 있었다. 관측의 오차와 자료의 손실로 역사자료를 이용한 강수 예측 방법은 절단자료의 분석을 중심으로 연구되었다. 대표적인 역사자료의 이용방법으로 조건부 적률을 이용한 B17B [Interagency Committee in Water Data, 1982], 조건부적률과적률 관계식을 이용한 Expected Moment Algorithm(EMA) [Cohn et al.;1997], 조건부 확률가중적률을 이용한 Partial Probability Weighted Moment (PPWM)[Wang ; 1991] 방법이 있다. 본 연구에서는 역사적 자료를 반영하는 방법에 있어 B17B와 EMA의 관계를 밝히고 그러한 관계가 PPWM에 동일하게 적용할 수 있음을 보였다. 우리는 B17B와 EMA의 관계를 적률방정식으로 표현하였고 PPWM에서 확률가중 적률 방정식을 정의함으로써 PPWM을 확장하였다. 본 연구에서 제안한 새로운 역사 자료를 이용한 강수예측 방법론을 Expected Probability Weighted Momemt (EPWM) 방법이라고 부르고 그 예측 방법의 성능을 다른 예측방법과 시뮬레이션 결과를 통해 비교하였다. 역사 자료 방법론의 비교는 Generalized Extreme Value (GEV) 분포를 이용하여 이루어졌으며, 각 방법론은 GEV분포의 형태모수(shape parameter)따라 다른 특성을 나타난다는 것을 보였다. 뿐만 아니라 여기서 제안한 EPWM 방법은 대부분의 경우에 좋은 추정량을 준다는 것을 보였다.

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Genetic Differences within and between Populations of Korean Catfish (S. asotus) and Bullhead (P. fulvidraco) Analysed by RAPD-PCR

  • Yoon, Jong-Man;Kim, Jong-Yeon
    • Asian-Australasian Journal of Animal Sciences
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    • 제17권8호
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    • pp.1053-1061
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    • 2004
  • Of the 20 arbitrarily chosen primers, six oligonucleotides decamer primers were used on the basis of the number of the polymorphisms generated in catfish (Silurus asotus) from Yesan and bullhead (Pseudobagrus fulvidraco) from Dangjin in Korea. Six primers were used generating a total of 602 scorable bands in catfish and 195 in bullhead population, respectively, ranging in size of DNA fragments from less than approximately 100 to larger than 2,000 base pairs (bp). Six primers yielded 199 polymorphic fragments (33.1%) in catfish and 47 (24%) in bullhead, respectively. In the present study, a total of 328 common fragments (an average of 54.7 per primer) were observed in catfish population, whereas 84 (an average of 14.0 per primer) in bullhead. The total number of specific fragments in catfish and bullhead population were 76 and 64, respectively. In catfish population, random decamer, OPA-17 (GACCGCTTGT) generated the highest number of fragments (a total of 141) in comparison with other primers used, with an average of 11.8. The common bands in the molecular weight of 300 bp generated by random primer OPA-06 (GGTCCCTGAC) were present in every individuals in bullhead population. The major polymorphic bands in the molecular weight of 100 bp generated by OPA-17 were identified in lane 14, 15, 17, 18, 19 20 and 21, which were identifying species in bullhead population. The average bandsharing values (BS values) of all of the samples within catfish population ranged from 0.575 to 0.945, whereas 0.063-1.000 within bullhead population. The bandsharing value (index of similarity between individuals) between individual No. 5 and No. 9 showed the highest level within catfish population, whereas the bandsharing value between individual No. 1 and No. 2 showed the lowest level. The single linkage cluster analysis resulted from four primers, indicating four genetic groupings composed of group 1 (C1-C10, all of the catfish samples), group 2 (B11, B12, B13, B14, B16, B17, B18, B19), group 3 (B15) and group 4 (B20 and B21). The dendrogram reveals close relationships between individual identities within two species populations and individuals derived from the same ancestor, respectively. However, genetic distances between two species populations ranged from 0.124 to 0.333. The shortest genetic distance (0.042) displaying significant molecular differences was between individual No. 6 and No. 9 catfish population. The shortest genetic distance (0.033) displaying significant molecular differences also was between individual No. 18 and No. 19 in bullhead population. Reversely, the genetic distance of individual No. 20/21 among individuals in bullhead population was highest (0.333). This result showed that bullhead No. 20 and 21 were distinct from other individuals within bullhead population.

LC/ESI/MS와 GC/TOF-MS를 이용한 인체뇨시료에서의 Prostanozol 대사체 검출 (Determination of metabolites of prostanozol in human urine by LC/ESI/MS and GC/TOF-MS)

  • 염태우;팽기정;김연제
    • 분석과학
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    • 제24권3호
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    • pp.173-182
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    • 2011
  • 약물(Prostanozol)을 복용한 여성을 대상으로 한 뇨시료 중에 함유된 Prostanozol 및 그 대사체들을 검출하기 위해 LC/ESI/MS와 GC/TOF-MS를 이용하여 효과적으로 분리 및 검출하였고, LC/ESI/MS의 질량스펙트럼으로부터는 각각의 분자량을 추정하였으며 GC/TOF-MS로는 이들을 확인하였다. M1은 Prostanozol의 17번 탄소가 케톤기로 치환된 17-keto-Prostanozol, M2는 M1에서 pyrazole nucleus 와 Aring에 한 개의 히드록시기가 치환된 hydroxy-17-keto-Prostanozol, M3는 B-ring 또는 C-ring에 한 개의 히드록시기가 치환된 hydroxy-17-keto-Prostanozol, M4는 한 개의 히드록시기가 D-ring에 치환된 hydroxy-17-keto-Prostsnozol로 확인되었으며 M5는 17번 탄소 위치에 히드록시기를 갖고 B-ring 또는 C-ring에서 하나의 히드록시기가 치환된 hydroxy-17-hydroxy-Prostanozol로 추정되며 M6은 17번 탄소 위치에 케톤기를 갖고 pyrazole nucleus 혹은 A-ring에 하나의 히드록시기를 또한 B-ring 또는 C-ring에 또 하나의 히드록시기가 치환된 dihydroxy-17-keto-Prostanozol, M7은 M6와 같이 17번 탄소에 케톤기를 갖으며 pyrazole nucleus 혹은 A-ring에 하나의 히드록시기를, 또한 D-ring에 또 하나의 히드록시기를 가진 dihydroxy-17-keto-Prostanozol로 확인되었다. 마지막으로 M8은 pyrazole nucleus 혹은 A-ring에 하나의 히드록시기를 갖고 그 외의 ring에 또 다른 히드록시기가 치환된 dihydroxy-17-hydroxy-Prostanozol임을 확인할 수 있었다. 이중 M5, M7, 그리고 M8은 지금까지 밝혀지지 않았던 새로운 대사체였다. 체내에서의 포합반응 여부를 확인한 결과 Prostanozol과 8종의 모든 대사체가 글루쿠론산 포합체를 형성하였고, 8종의 대사체 중 일부는 포합체를 형성하지 않고도 배출되며 특히 M6과 M7은 황산 포합체로도 배설되는 것을 확인할 수 있었다.

Higher Expression of TRPM7 Channels in Murine Mature B Lymphocytes than Immature Cells

  • Kim, Jin-Kyoung;Ko, Jae-Hong;Nam, Joo-Hyun;Woo, Ji-Eun;Min, Kyeong-Min;Earm, Yung-E;Kim, Sung-Joon
    • The Korean Journal of Physiology and Pharmacology
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    • 제9권2호
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    • pp.69-75
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    • 2005
  • TRPM7, a cation channel protein permeable to various metal ions such as $Mg^{2+}$, is ubiquitously expressed in variety of cells including lymphocytes. The activity of TRPM7 is tightly regulated by intracellular $Mg^{2+}$, thus named $Mg^{2+}$-inhibited cation (MIC) current, and its expression is known to be critical for the viability and proliferation of B lymphocytes. In this study, the level of MIC current was compared between immature (WEHI-231) and mature (Bal-17) B lymphocytes. In both cell types, an intracellular dialysis with $Mg^{2+}$-free solution (140 mM CsCl) induced an outwardly-rectifying MIC current. The peak amplitude of MIC current and the permeability to divalent cation ($Mn^{2+}$) were several fold higher in Bal-17 than WEHI-231. Also, the level of mRNAs for TRPM7, a molecular correspondence of the MIC channel, was significantly higher in Bal-17 cells. The amplitude of MIC was further increased, and the relation between current and voltage became linear under divalent cation-free conditions, demonstrating typical properties of the TRPM7. The stimulation of B cell receptors (BCR) by ligation with antibodies did not change the amplitude of MIC current. Also, increase of extracellular $[Mg^{2+}]_c$ to enhance the $Mg^{2+}$ influx did not affect the BCR ligation-induced death of WEHI-231 cells. Although the level of TRPM7 was not directly related with the cell death of immature B cells, the remarkable difference of TRPM7 might indicate a fundamental change in the permeability to divalent cations during the development of B cells.

사전위상 왜곡을 이용한 IEEE 802.11a OFDM 무선랜 전력증폭기 위상왜곡 특성분석 (Analysis of Power Amplifier Phase Distortion Characteristics for IEEE 802.11a OFDM Wireless LAM Using Phase Predistortion)

  • 오정균;최재홍;구경헌
    • 대한전자공학회논문지TC
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    • 제42권2호
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    • pp.75-80
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    • 2005
  • 본 논문에서는 5.8GHz 무선랜에 적용할 수 있는 전력증폭기를 설계 및 제작하였다. 제작된 전력증폭기는 2단으로 구성되며 측정결과 중심주파수 5.8GHz에서 21.6dBm의 PldB 출력전력과 100MHz 대역에서 17.6dB 이득과 -17.8dB 이하의 입력반사손실을 얻었다. 설계된 전력증폭기의 왜곡과 출력 ACPR 관계를 분석하기위해, 최대 54Mbps의 전송속도를 가지는 IEEE 802.11a OFDM 변조부와 송신부를 모델링하였다. 전력증폭기의 비선형특성은 behavioral model을 이용하여 AM-to-AM과 AM-to-PM으로 모델링하였으며, 위상 왜곡에 따른 출력스펙트럼 특성을 해석하였다. IEEE 802.11a 무선랜 시스템의 요구 출력스펙트럼 마스크를 만족하기위한 PldB로부터 back-off값을 구하기 위하여 위상왜곡에 따른 전력증폭기의 ACPR 특성을 시뮬레이션하고 사전왜곡방식을 이용하여 증폭기의 위상왜곡을 변화시키며 측정한 결과와 시뮬레이션 특성을 비교 제시하였다.

P-HEMT를 이용한 능동 안테나용 X-Band MMIC 저잡음 증폭기 설계 및 제작 (The Design and Fabrication of X-Band MMIC Low Noise Amplifier for Active antennal using P-HEMT)

  • 강동민;맹성재;김남영;이진희;박병선;윤형섭;박철순;윤경식
    • 한국전자파학회논문지
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    • 제9권4호
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    • pp.506-514
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    • 1998
  • 능동 안테나용 X-band(11.7~12 GHz)단일 칩 초고주파 집적회로(Monolithic Microwave Integrated Circuits, MMICs) 저잡음 증폭기(Low Noise Amplifier, LNA)를 $0.15{\mu}m\times140{\mu}m$ AlGaAs/InGaAs/GaAs 고속 전자 이동도 트랜지스터(Pseudomorphic-High Electron Mobility Transistor, P-HEMT)를 이용하여 2단으로 설계하고 제작하였다. 증폭기의 안정도 특성을 위해 이득이 다소 감소하나 입력정합이 쉽고 안정도가 좋은 소스 인턱터를 사용하여 저잡음증폭기를 설계하였다. 동작 주파수에서 약 17dB의 이득, 1.3 dB의 잡음 지수 그리고 입.출력 반사손실은 -17~-15dB를 측정 결과로서 얻었다. 이러한 측정 결과는 잡음 지수를 제외하고는 설계 결과와 거의 일치하며, 제작된 MMIC LNA의 칩 크기는 $1.43\tiems1.27mm^2$이다.

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Rotational Contour Analysis of the Vibronic Bands in the High Resolution Emission Spectra of the Benzyl Radical

  • 최익순;한명선;이상국
    • Bulletin of the Korean Chemical Society
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    • 제17권10호
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    • pp.882-885
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    • 1996
  • The 6a10 and 6b10 vibronic bands in the 12A2-12B2 electronic transition of the emission spectra of the benzyl radical obtained using a high resolution Fourier transform spectrometer are rotationally analyzed. The observed rotational contours were fitted by computer simulated rotational contours, providing determination of the variations, ΔA, ΔB, and ΔC of the rotational constants accompanying the vibronic transitions corresponding to each band. The molecular rotational constants A, B, and C are revised for the upper state and for the two lower states, respectively.

Effects of 17b-Estradiol on the Inducible Nitric Oxide Synthase Expression in macrophages

  • Kim, Ji-Young;Cho, Young-Rhan;Jeong, Hye-Gwang
    • 대한약학회:학술대회논문집
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    • 대한약학회 2003년도 Proceedings of the Convention of the Pharmaceutical Society of Korea Vol.1
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    • pp.171.1-171.1
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    • 2003
  • In some tissues 17b-estradiol (E2) is known to increase endothelial NOS expression. In the present study we examined the effects of E2 on estrogen receptors (ERa and b) and inducible nitric oxide synthase (iNOS) expression and analyzed the mechanisms in rat peritoneal macrophages. (omitted)

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