• Bulletin of the Korean Chemical Society
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• v.26 no.12
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• pp.1921-1922
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• 2005

• Proceedings of the Korea Environmental Mutagen Society Conference
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• 2002.11a
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• pp.187-187
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• 2002

• Bulletin of the Korean Chemical Society
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• v.34 no.12
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• pp.3543-3544
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• 2013

• Bulletin of the Korean Chemical Society
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• v.34 no.12
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• pp.3863-3866
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• 2013

• Bulletin of the Korean Chemical Society
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• v.32 no.12
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• pp.4415-4418
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• 2011

• Bulletin of the Korean Chemical Society
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• v.23 no.12
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• pp.1839-1841
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• 2002

• Proceedings of the Korean Society of Toxicology Conference
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• 2002.11b
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• pp.187-187
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• 2002

Recent studies suggest that inflammatory events are implicated in a variety of human diseases including cancer and neurodegenerative diseases, and non-steroidal anti-inflammatory drugs have beneficial effects in treatment or prevention of these disorders.(omitted)

• Journal of the Optical Society of Korea
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• v.12 no.4
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• pp.364-364
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• 2008

• Archives of Pharmacal Research
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• v.25 no.6
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• pp.820-823
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• 2002

The diethylet er fraction from the leaves extract of Ligularia fischeri var. spiciformis (Compositae) was subjected to silica gel column chromatography and yielded three new terpenoids named spiciformisin a (1), spiciformisin b (3), and monocyclosqualene (2). Acyclic diterpenes, spiciformisin a and -b, were established as 3,7,11,15-tetramethyl-1,3(20)-hexadecadiene and 3,7,11,15-tetramethyl-1,3,6,10,14-hexadecapentaene (IUPAC), respectively. A monocyclic triterpene, monocyclosqualene, were determined as [3,8,12,16,16-pentamethyl-(3,7,11,15-hexadecatetraenyl)]-3,3,5-trimethyl-1-cyclohexene. The structures were determined on the basis of NMR and MS analysis. Spiciformicin b showed potent cytotoxicity ($IC_{50},{\;}<9.7{;\}{\mu\textrm{g}}/ml$ against HL-60) in contrast to no cytotoxicity ($IC_{50},{\;}>200{\;}}{\mu\textrm{g}}/ml against HL-60 cells) of spiciformicin a with a cis-conjugated dienyl diexomethylene.

• Childhood Kidney Diseases
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• v.12 no.2
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• pp.256-261
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• 2008

Rhabdomyolysis is a syndrome involving the breakdown of skeletal muscle causing myoglobin and other intracellular proteins and electrolytes to leak into the circulation. There are various causes of acute rhabdomyolysis in childhood, such as direct trauma to muscle, muscle necrosis from ischemia, inflammation in muscle, or exposure to drugs and toxins. The most-important complication of this disorder is acute renal failure (ARF). However, the contributing factors to the development of ARF in children with rhabdomyolysis remain obscure. We report two cases of rhabdomyolysis after excessive exercise.