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Binary Segmentation Procedure for Detecting Change Points in a DNA Sequence

  • Yang Tae Young;Kim Jeongjin
    • Communications for Statistical Applications and Methods
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    • v.12 no.1
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    • pp.139-147
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    • 2005
  • It is interesting to locate homogeneous segments within a DNA sequence. Suppose that the DNA sequence has segments within which the observations follow the same residue frequency distribution, and between which observations have different distributions. In this setting, change points correspond to the end points of these segments. This article explores the use of a binary segmentation procedure in detecting the change points in the DNA sequence. The change points are determined using a sequence of nested hypothesis tests of whether a change point exists. At each test, we compare no change-point model with a single change-point model by using the Bayesian information criterion. Thus, the method circumvents the computational complexity one would normally face in problems with an unknown number of change points. We illustrate the procedure by analyzing the genome of the bacteriophage lambda.

Current Distribution on a Six Points Fed Linear Antenna (육점급전안테나의 전류분포)

  • 박정기
    • Journal of the Korean Institute of Telematics and Electronics
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    • v.6 no.3
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    • pp.12-23
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    • 1969
  • In this paper, the current distribution on a 6 points fed linear antenna is theoretically introduced. The antenna that we call the 6 points fed linear antenna is an antenna which are fed by emf E1 at the first two points, emf E2 at the second two points, and emf E3 at the third two points. symmetrical with respect to the center. In this analysis, Hallens theory has been extended with the approximation in the same order.

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Statistical comparison of the analytical results of heavy metal contents in the riverside soil from the various methods of selecting sampling points (강변 토양내 중금속 분석에서 시료 채취 지점 선정방법에 따른 결과들의 통계적 비교)

  • 박광재;문병철
    • Journal of Environmental Science International
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    • v.6 no.1
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    • pp.33-44
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    • 1997
  • In investigating heavy metal contents at specific areas, the method of selecting sampling points is Important A general method is, according to the law , random sampling of zigzag-form in the selected field. In this work, we studied whether the measured values obtained from a certain method of selecting sampling points is a representative of heavy metal contents in the selected field or not. The selected field for this study is located on the lower Yangsan-river: Gasan-li, Mulgum-myon, Yangsan-gun, KyoungNam, 1 km away from the mi, h stream of Nakdong river. The heavy metals investigated were Cd, Cr, Cu, Fe, Mn, Ni, Pb, and Zn. The inductively coupled plasma(ICPI atomic emission spectrometer was used to measure these metals quantitatively. The number of total sampling points were 24. We compared the total mean values with the mean obtained from various methods of selecting sampling points.

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Pain-relieving Effect of the PAS Release Applied to Tender Points (압통점에 적용한 파스이완술이 통증에 미치는 영향)

  • Park, Ji-Whan
    • The Journal of Korean Academy of Orthopedic Manual Physical Therapy
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    • v.5 no.1
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    • pp.53-58
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    • 1999
  • PURPOSE; The main purpose of physical therapy is to minimize patient's pain. So this study aimed at evaluating the effect of PAS release applied to tender points in reducing pain of musculoskeletal lesion persons. METHOD; The PAS (capsicum plaster) Release applied at 48 tender points to relieve and assessment pain threshold by Harold Gottlieb's pain scale that was composed of Negligible sensation 4.00, Mild sensation 3.00, Moderate sensation 2.00, Severe sensation 1.00. RESULT; Results show that PAS release was 84.6% effect in achieving a gradual decrease of pain sensitivity at the tender points where it was applied, suggestion a cumulative analgesic effect through sessions. CONCLUSION; This study suggests that PAS release applied to tender points can be effective in relieving soft tissue pain through theses have not become asymptomatic, all referred significant pain relief(p <0.05) after study and at the end of PAS release therapy.

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The Exploring of the Device for Creativity Estimating Applied Causal Maps (인과지도를 통한 창의성검사 방안 탐색)

  • Moon, Byoung-Chan
    • Korean System Dynamics Review
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    • v.12 no.1
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    • pp.131-153
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    • 2011
  • The purpose of this study is to explore the applicability of the causal maps for estimating creativity. This study assumes that fluency, flexibility, originality and elaboration are elements of creativity; and there are common characteristics between systems and creative thinking. For this study, 30 students from the 5th grade create causal maps which are consisted of the contents of 'the water cycle in the earth'. The causal maps are analyzed and evaluated by focusing on the characteristics of creativity. In way of the marking causal maps based on creativity, each word is scored as 1 point on the basis of 30 points for fluency. Each word which is linked more than one word is scored 3 points for flexibility, but the maximum points are limited as 35 points. In originality, if it is approved each word is worthy as well as originality, it is scored as 10 points on the basis of 40 points. Lastly, each number of cycle loops is scored as 15 points for elaboration, and the maximum scores are limited as 45 points. As is stated above, the limiting of the maximum scores are designed based on corresponded to 10% students of participators. In the result of this study, the students' scores of evaluating creativity applied causal maps show similar patterns from relative point of view to the other results which were evaluated the creativity by credible organ. Consequently, it is recognized that the causal maps have the possibility of being able to estimate quantitatively the creativity.

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The Turbulent Natural Convection in Membrane Type LNG Carrier Cofferdam (멤브레인형 LNG 수송선 코파담내의 난류 자연대류)

  • Chung, Han Shik;Jeong, Hyo Min;Kim, Kyung Kun;Ro, Sung Tack
    • Transactions of the Korean Society of Mechanical Engineers B
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    • v.23 no.2
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    • pp.281-287
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    • 1999
  • The turbulent natural convection in the membrane type LNG carrier cofferdam with heating points has been studied by numerical method. As the numerical methods, we introduced the three turbulence model, a standard $k-{\varepsilon}$ model and two case of a low Reynolds number models. The parameters considered for this study ore number and capacity of heating points i.e., $1{\leq}Ns{\leq}12$ and $1.0{\times}10^5{\leq}Qs(W/m^3){\leq}1.0{\times}10^8$. The results of the isotherms and velocity vectors have been represented for various parameters. The temperature and velocity at upper position in the space ore shown to be higher than those at lower position. For obtaining the optimal temperatures, $20{\sim}30^{\circ}C$ in the cofferdam space, the heating capacities show $2.0{\times}10^7W/m^3$ at g-heating points and $1.0{\times}10^7W/m^3$ at 12-points. The mean temperature in the cofferdam space can be expressed as a function of number and capacity of heating points.

Virtual reality training simulator for tooth preparation techniques

  • Jung, HeeSuk;Kim, HyoJoon;Moon, SeongYong
    • Oral Biology Research
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    • v.42 no.4
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    • pp.235-240
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    • 2018
  • Standard oral and maxillofacial three-dimensional model was developed with patients' medical data while virtual reality (VR) simulator was developed in conjunction with head mount display (HMD) and Haptic device. The objective of this study was to evaluate the preclinical use of a VR training simulator in tooth preparation practice. Eighty-nine dental students were trained how to operate the simulator. The participants were then given sufficient time on the simulator to practice dental preparation. The students experience and opinion was then taken in through filling of questionnaires. On average content received 1.8 points, anatomy had 2.5 points, 2.6 points for the applicability, and 2.0 for the usability. As for the detailed items scores, queries about the possible development of the simulator and the interest of the learning process through the simulator were the highest at 3.1 and 3.0 points, respectively. Question about the benefit of the HMD and the haptic device during the practice had 1.5 and 1.6 points, respectively. The average total score was 2.2 points. VR tooth preparation simulator in the field of clinical dental education has powerful potential in regard to realistic models, environments, vision, posture, and economical efficiency.

A Comparative Study on Complaints of Menopausal Symptom of Nuns and Married Women (수녀와 기혼여성의 갱년기증상 호소에 관한 비교연구)

  • 유명숙
    • Journal of Korean Academy of Nursing
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    • v.30 no.1
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    • pp.18-28
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    • 2000
  • The Purpose of this study is to extend the understanding and knowledge of menopause by comparing menopausal symptoms of married women and nuns in order to improve health and the quality of life for women. In this study a questionnaires were distributed to 116 nuns and 121 married women, from forty to fifty nine years old in Daegu metropolitan city. This study used the measurement of menopausal symptoms (Cronbach's Alpha=0.96) corrected and complemented by this student with consideration of various literature centered around menopausal symptoms, suggested by Janette M. Perz as 51 questions including 4 realms; [mental psychological factors], [physical physiological factors], [eyesight factors], and [urinary generative factors] in order to measure the degree of menopausal symptoms. The results are as follows : 1. There was a significant difference between educational background, religion, occupation, leisure time, satisfaction of marriage or ascetic life, existence of hormonal treatment, name of medical operation, and existence of counselling about menstruation as general and physiological characteristics of the nuns' group and the married women's group. 2. The menopausal symptoms of the nuns' group and the married women's group according to order in which they were presented were; 'feeling tired and lacking in energy(1.71 points)' 'vision not clear or clouded(1.69 points)', and 'be forgetful (1.57 points)' in nuns' group. 'be forgetful (1.87 points)', 'vision not clear or clouded(1.83 points)' and 'feeling tired and lacking in energy(1.76 points)' in the married women's group. The symptoms which showed the highest rank of menopausal symptoms had a maximum score of 4 points. 3. There was a statistical a significance (t=-3.9807, p<.0001) between the two groups which showed, on an average, 57.92 points in the married women's group and 43.03 points in the nuns' group from 0 to 196 of the possible points of menopausal symptoms. In difference of menopausal symptoms by menstrual aspect of the nuns' group and the married women's group, there was statistically significant difference between the two groups, showing 44.81±26.07 score in the nuns' group and 72.33±35.29 score in the married women's group as the mean score of the groups with no menstruation(t=-4.1132, p=0.0001). 4. The differences in menopausal symptoms with respect to the general and physiological characteristics of the nuns' group and the married women's group were that the nuns' group showed less menopausal symptoms on all the items than that of the married women's group. Finally, in these results, the married women's group showed higher menopausal symptoms than that of the nuns' group. Especially as the score of menopausal symptoms since the climacteric was very high it is confirmed to be a new phenomenon. Accordingly, it is considered to be necessary to carry out an indepth study of the factors related to establishing a strategy for nursing service.

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EXISTENCE OF THREE SOLUTIONS FOR A CLASS OF NAVIER QUASILINEAR ELLIPTIC SYSTEMS INVOLVING THE (p1, …, pn)-BIHARMONIC

  • Li, Lin
    • Bulletin of the Korean Mathematical Society
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    • v.50 no.1
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    • pp.57-71
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    • 2013
  • In this paper, we establish the existence of at least three solutions to a Navier boundary problem involving the ($p_1$, ${\cdots}$, $p_n$)-biharmonic systems. We use a variational approach based on a three critical points theorem due to Ricceri [B. Ricceri, A three critical points theorem revisited, Nonlinear Anal. 70 (2009), 3084-3089].