• Title/Summary/Keyword: 1-MX

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Hologram Quantitative Structure Activity Relationship (HQSAR) Study of Mutagen X

  • Cho, Seung-Joo
    • Bulletin of the Korean Chemical Society
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    • v.26 no.1
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    • pp.85-90
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    • 2005
  • MX and its analogs are synthesized and modeled by quantitative structure activity relationship (QSAR) study including comparative molecular field analysis (CoMFA). As a result, factors affecting this class of compounds have been found to be steric and electrostatic effects. Because hologram quantitative structure activity relationship (HQSAR) technique is based on the 2-dimensional descriptors, this is free of ambiguity of conformational selection and molecular alignment. In this study we tried to include all the data available from the literature, and modeled with the HQSAR technique. Among the parameters affecting fragmentation, connectivity was the most important one for the whole compounds, giving good statistics. Considering additional parameters such as bond specification only slightly improved the model. Therefore connectivity has been found to be the most appropriate to explain the mutagenicity for this class of compounds.

Development of 6-component Force/Moment Calibration Machine (6분력 힘/모멘트 교정기의 개발)

  • 김갑순;강대임
    • Journal of the Korean Society for Precision Engineering
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    • v.15 no.9
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    • pp.127-134
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    • 1998
  • This paper describes the design of a 6-component force/moment calibration machine with having the maximum capacities of 500 N in forces and 50 Nm in moments. To be used for the characteristic of a multi-component load cell. this machine consists of a body, a fixture, a force generating system, a moment generating system and weights. We have also evaluated the accuracy of the calibration machine. Test results show that the expanded relative uncertainty for force components $\pmFx,\;\pmFy\;and\;moment\;components\;\pmMx,\;\pmMy\;are\;less\; than\;8.6\times10^{-4}$, and force components +Fz, -Fz and moment components $\pmMz\;is\;less\;than\;1.6\times10^{-3},\;2.0\times10^{-5},\;1.7\times10^{-3}$ respectively.

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Fabrication and Characterization of Hexagonal Tungsten Oxide Nanopowders for High Performance Gas Sensing Application (육방정계 텅스텐옥사이드 나노분말의 합성과 고성능 가스센서응용을 위한 성능 평가)

  • Park, Jinsoo
    • Journal of Powder Materials
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    • v.26 no.1
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    • pp.28-33
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    • 2019
  • The gas sensor is essential to monitoring dangerous gases in our environment. Metal oxide (MO) gas sensors are primarily utilized for flammable, toxic and organic gases and $O_3$ because of their high sensitivity, high response and high stability. Tungsten oxides ($WO_3$) have versatile applications, particularly for gas sensor applications because of the wide bandgap and stability of $WO_3$. Nanosize $WO_3$ are synthesized using the hydrothermal method. As-prepared $WO_3$ nanopowders are in the form of nanorods and nanorulers. The crystal structure is hexagonal tungsten bronze ($MxWO_3$, x =< 0.33), characterized as a tunnel structure that accommodates alkali ions and the phase stabilizer. A gas detection test reveals that $WO_3$ can detect acetone, butanol, ethanol, and gasoline. This is the first study to report this capability of $WO_3$.

Development of Novel Joint Device for a Disposal Canister in Deep Borehole Disposal (고준위폐기물 심부시추공 처분을 위한 처분용기 접속장치의 개발)

  • LEE, Minsoo;LEE, Jongyoul;JI, Sung-Hoon
    • Journal of Nuclear Fuel Cycle and Waste Technology(JNFCWT)
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    • v.16 no.2
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    • pp.261-270
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    • 2018
  • In this study, to replace the 'J-slot joint', a joint device between a disposal canister and an emplacement jig in Deep Borehole Disposal process, a novel joint device was designed and tested. The novel joint device was composed of a wedge on top of a disposal canister and a hook box at the end of a winch system. The designed joint device had merits in that it can recombine an emplaced canister freely without the replacement of the joint component. Moreover, it can be applied to various emplacement jigs such as drill pipes, wire-lines, and coiled tubing. To demonstrate the designed joint device, the joint device (${\Phi}110mm$, H 148 mm), a twin canister string (${\Phi}140mm$, H 1,105 mm), and a water tube (${\Phi}150mm$, H 1,500 mm) as a borehole model were manufactured at 1/3 scale. As deployment muds, Na-type bentonite (MX-80) and Ca-type (GJ II) bentonite muds were prepared at solid contents of 7wt% and 28wt%, respectively. The manufactured joint device showed good performance in pure water and viscous muds, with an operation speed of $10m{\cdot}min^{-1}$. It was concluded that the newly developed joint device can be used for the emplacement and retrieval of a deep disposal canister, below 3~5 km, in the future.

CKFont2: An Improved Few-Shot Hangul Font Generation Model Based on Hangul Composability (CKFont2: 한글 구성요소를 이용한 개선된 퓨샷 한글 폰트 생성 모델)

  • Jangkyoung, Park;Ammar, Ul Hassan;Jaeyoung, Choi
    • KIPS Transactions on Software and Data Engineering
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    • v.11 no.12
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    • pp.499-508
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    • 2022
  • A lot of research has been carried out on the Hangeul generation model using deep learning, and recently, research is being carried out how to minimize the number of characters input to generate one set of Hangul (Few-Shot Learning). In this paper, we propose a CKFont2 model using only 14 letters by analyzing and improving the CKFont (hereafter CKFont1) model using 28 letters. The CKFont2 model improves the performance of the CKFont1 model as a model that generates all Hangul using only 14 characters including 24 components (14 consonants and 10 vowels), where the CKFont1 model generates all Hangul by extracting 51 Hangul components from 28 characters. It uses the minimum number of characters for currently known models. From the basic consonants/vowels of Hangul, 27 components such as 5 double consonants, 11/11 compound consonants/vowels respectively are learned by deep learning and generated, and the generated 27 components are combined with 24 basic consonants/vowels. All Hangul characters are automatically generated from the combined 51 components. The superiority of the performance was verified by comparative analysis with results of the zi2zi, CKFont1, and MX-Font model. It is an efficient and effective model that has a simple structure and saves time and resources, and can be extended to Chinese, Thai, and Japanese.

Radiographic evaluation of computer aided design/computer aided manufacturing (CAD/CAM) customized abutment of implant (CAD/CAM으로 제작된 임플란트 맞춤형 지대주의 방사선학적 평가)

  • Yun, Tae-Gyeong;Lee, Gyeong-Je;Chung, Chae-Heon;Kim, Hee-Jung
    • The Journal of Korean Academy of Prosthodontics
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    • v.55 no.3
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    • pp.258-263
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    • 2017
  • Purpose: In this study, the retrospective radiographic study is executed to evaluate amount of bone loss of various conditions in patients using customized abutment for 4 years of follow-up. Materials and methods: The subjects of this study were implant fixed dental prosthesis using CAD/CAM customized abutments. CAD/CAM customized abutment and fixed dental prosthesis were manufactured by the Prosthodontics Department of Chosun University Dental Hospital from August 1, 2011 to July 31, 2012. Radiological assessments were performed on the patients who were treated by the fixed prosthodontics. After each treatment, a retrospective study was performed for a total of 4 years at 3 months, 6 months, 1 year, 2 years, 3 years, and 4 years. Results: As a result of the study, the customized abutment using CAD/CAM showed less bone loss than the results of existing research. There was no statistically significant differences at alveolar bone loss between splinting group and non-splinting group (respectively 0.27 mm, 0.5 mm). Also, there were statistically significant differences at alveolar bone loss in mx. anterior, mx. posterior, mn. anterior and mn. posterior part (respectively 1.37 mm, 0.39 mm, 0.00 mm, 0.30 mm). Conclusion: The customized abutment using CAD/CAM showed less bone loss than the results of existing research, there were statistically significant differences at alveolar bone loss in implant positions.

Noise Characteristics of 64-channel 2nd-order DROS Gradiometer System inside a Poorly Magnetically-shielded Room (저성능 자기차폐실에서 64채널 DROS 2차 미분계 시스템의 잡음 특성)

  • Kim, J.M.;Lee, Y.H.;Yu, K.K.;Kim, K.;Kwon, H.;Park, Y.K.;Sasada, Ichiro
    • Progress in Superconductivity
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    • v.8 no.1
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    • pp.33-39
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    • 2006
  • We have developed a second-order double relaxation oscillation SQUID(DROS) gradiometer with a baseline of 35 mm, and constructed a poorly magnetically-shielded room(MSR) with an aluminum layer and permalloy layers for magnetocardiography(MCG). The 2nd-order DROS gradiometer has a noise level of 20 $fT/{\surd}Hz$ at 1 Hz and 8 $fT/{\surd}Hz$ at 200 Hz inside the heavily-shielded MSR with a shielding factor of $10^3$ at 1 Hz and $10^4-10^5$ at 100 Hz. The poorly-shielded MSR, built of a 12-mm-thick aluminum layer and 4-6 permalloy layers of 0.35 mm thickness, is 2.4mx2.4mx2.4m in size, and has a shielding factor of 40 at 1 Hz, $10^4$ at 100 Hz. Our 64-channel second-order gradiometer MCG system consists of 64 2nd-order DROS gradiometers, flux-locked loop electronics, and analog signal processors. With the 2nd-order DROS gradiometers and flux-locked loop electronics installed inside the poorly-shielded MSR, and with the analog signal processor installed outside it, the noise level was measured to be 20 $fT/{\surd}Hz$ at 1 Hz and 8 $fT/{\surd}Hz$ at 200 Hz on the average even though the MSR door is open. This result leads to a low noise level, low enough to obtain a human MCG at the same level as that measured in the heavily-shielded MSR. However, filters or active shielding is needed fur clear MCG when there is large low-frequency noise from heavy air conditioning or large ac power consumption near the poorly-shielded MSR.

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Analysis of Residual Solvents of [F-18]FDG Using Gas Chromatography (기체크로마토그래프법을 이용한 [F-18]FDG의 잔류용매 분석)

  • Kim, Dong-Il;Lee, Il-Jung;Kim, Shi-Hwal;Chi, Yong-Gi;Seok, Jae-Dong
    • The Korean Journal of Nuclear Medicine Technology
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    • v.15 no.2
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    • pp.26-29
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    • 2011
  • Purpose: The general test method of the Korean Pharmacopeia specifies the test method on the clauses of quality control after manufacturing. According to KFDA Guidance for Medicines, standards of residual solvents regulates the maximum permissible dose of acetonitrile as 400 ppm, ethanol as 5,000 ppm, and acetic acid as 5,000 ppm. This study aims at identifying the type of resiual solvents in the final [F-18]FDG vial of an automatic synthesizer and measure its residual quantity. Materials and Methods: The center carried out residual solvents test of [F-18]FDG injection using Agilent Technologies 7890A with a Flame Ionization Detector. The column of Agilent Technologies 7890A used in measuring of residual solvents was CP WAX column ($30m{\times}0.53mm{\times}1.0{\mu}m$) and analysis condition was split mode 1:1 at the initial temperature $70^{\circ}C$ which was increased $20^{\circ}C/minute$ after two minutes and maintained at the final $140^{\circ}C$ for two minutes. The analysis method was as following: Firstly, ethanol-acetonitrile-acetic acid mixture was classified into four types of concentration (250-25-250 ppm, 1,000-100-1,000 ppm, 3,000-300-3,000 ppm, and 6,000-600-6,000 ppm), and $1.0{\mu}L$ of each type of concentration was injected into gas chromatography followed by an analysis of its peak domain. Then, a calibration-curve by the external standard method was drawn based on the analysis result. Results: While ethanol and acetonitrile were detected in TRACERlab MX, FASTlab had additional acetic acid. The residual quantity of the ethanol-acetonitrile-acetic acid mixture evaluated using the calibration-curve was average 72 ppm ethanol, 54 ppm acetonitrile, and 1030 ppm acetic acid for FASTlab, whereas average 439 ppm ethanol and 79 ppm acetonitrile for TRACERlab MX. This indicated that both of them were within the maximum permissible dose. Conclusion: Solvent residues in the [F-18]FDG injection were all within maximum permissible doses and proper to be used to examine a patient. The result indicated that types and quantities of solvent resides of radioactive pharmaceuticals vary depending on the automatic synthesizer.

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Multiple Parallel-Pollard's Rho Discrete Logarithm Algorithm

  • Lee, Sang-Un
    • Journal of the Korea Society of Computer and Information
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    • v.20 no.8
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    • pp.29-33
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    • 2015
  • This paper proposes a discrete logarithm algorithm that remarkably reduces the execution time of Pollard's Rho algorithm. Pollard's Rho algorithm computes congruence or collision of ${\alpha}^a{\beta}^b{\equiv}{\alpha}^A{\beta}^B$ (modp) from the initial value a = b = 0, only to derive ${\gamma}$ from $(a+b{\gamma})=(A+B{\gamma})$, ${\gamma}(B-b)=(a-A)$. The basic Pollard's Rho algorithm computes $x_i=(x_{i-1})^2,{\alpha}x_{i-1},{\beta}x_{i-1}$ given ${\alpha}^a{\beta}^b{\equiv}x$(modp), and the general algorithm computes $x_i=(x_{i-1})^2$, $Mx_{i-1}$, $Nx_{i-1}$ for randomly selected $M={\alpha}^m$, $N={\beta}^n$. This paper proposes 4-model Pollard Rho algorithm that seeks ${\beta}_{\gamma}={\alpha}^{\gamma},{\beta}_{\gamma}={\alpha}^{(p-1)/2+{\gamma}}$, and ${\beta}_{{\gamma}^{-1}}={\alpha}^{(p-1)-{\gamma}}$) from $m=n={\lceil}{\sqrt{n}{\rceil}$, (a,b) = (0,0), (1,1). The proposed algorithm has proven to improve the performance of the (0,0)-basic Pollard's Rho algorithm by 71.70%.

Conflict-Free Memory System for Subarray Access (서브어레이 접근을 위한 충돌회피 기억장치)

  • 박춘자;박종원
    • Proceedings of the Korean Information Science Society Conference
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    • 2002.04a
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    • pp.43-45
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    • 2002
  • 이 논문에서는 pq개의 PE(Processing Element)를 가진 SIMD처리기에서 기억 장치 접근시간을 감소시키기 위한 충돌회피 기억장치를 제안했다. 이 기억장치는 MxN 배열내 자료들의 임의의 위치에서 일정 간격인 블록형태와 8방향 선형태인 pd개의 자료들의 동시 접근을 지원한다. 기억모듈 수는 pq보다 큰 소수이고, 간격은 기억모듈 수의 배수가 아닌 양수이다. 간단하고 빠른 주소계산회로와 이동회로를 위해, 요구된 자료들에서 첫번째 자료의 기준 주소와 pq개의 주소간의 차들로 구분한 후, 주소간의 차들은 첫번째 자료 요소의 기억모듈번호로부터 번호에 따라 오름차순 정렬되고 빠른 기억모듈에 저장된다. 그래서 m개의 주소간의 차이들에 첫번째 자료의 기준주소 더해진 후, 첫 번째 요소의 기억모듈 번호에 의한 오른쪽 회전이 간격을 가진 9가지 서브어레이 모두이게 요구된다. 9가지 자료 이동 형태를 멀티플렉싱과 회전에 의해 1가지로 감소시킨 효율적인 자료 이동 회로를 제안하였다. 제안된 충돌회피기억 장치는 이전기억 장치와 비교하여 자료 접근형태, 간격, 자료 배열의 크기에 제한, 하드웨어 비용, 속도, 복잡도면에서 개선하였다.

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