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The Comparison of Glomerular Filteration Rate by Kidney Depth in Dynamic kidney Scan (동적신장검사에서 신장깊이에 따른 사구체여과율 비교)

  • Hwang, Ju-Won;Lim, Young-Hyen;Yun, Jong-Jun;Lee, Hwa-Jin;Lee, Mu-Seok;Jung, Ji-Uk;Park, Se-Yun
    • The Korean Journal of Nuclear Medicine Technology
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    • v.18 no.2
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    • pp.73-77
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    • 2014
  • Purpose Find out about the significance of the GFR values calculated by the kidney depth is measured by comparing the values obtained for kidney depth was measured GFR in the CT image kidney depth and is calculated by Tonnesen law in $^{99m}Tc$-DTPA dynamic kidney scan with each applies. Materials and Methods Among patients with normal value (75~120 mL/min) computed GFR conducted of dynamic renal scan to visit from February 2013 to February 2014 and donor GFR values in patients with normal value. The mean age was 46.9 years with 14 men 13 females. We used abdomen CT image which checked before conducting dynamic Kidney scan for measuring the depth of kidney. We only used CT image that contains renal hilum and measured outermost front of the kidney from the skin surface (a) and the final surface (b) caculated the average depth of [(a + b) / 2] respectively. Using the same ROI in order to limit the change in GFR values by the other additional element was set before and after the depth value was excluded from the GFR falls kidney disease. Results Using Tonnesen law the average value was caculated 5.94 cm from the right kidney 5.90 cm from the left kidney. It was 6.83 cm, 8.71 cm in the left kidney and the right kidney average value of the depth measured on the basis of the CT image. The respective increase in left kidney 0.93 cm and right kidney 2.77 cm calculated on the basis of CT image actually measured values. GFR was calculated as the average depth of the subject calculated by the method Tonnesen $83.3{\pm}9.79mL/min$. $98.6{\pm}14.07mL/min$ GFR was applied to calculate the average depth of the subjects using the CT image, is the difference appears 15.26 mL/min was increased after seting up depth value, P value was less than 0.01 which is significant. Conclusion The difference between GFR before-after setting up depth value cause that the different of depth value. Is a measured depth of the extension value of the calculated estimates Whereas Tonnesen kidney depth method is to use in calculating the value of GFR in a typical dynamic elongation test depth derived using the CT image depth. Is thought to be able to calculate more accurately the GFR value by the distance to the center of kidney more accurately measured in the skin thereby.

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Evaluation on the Usefulness of Alternative Radiopharmaceutical by Particle size in Sentinel Lymphoscintigraphy (감시림프절 검사 시 입자크기에 따른 대체 방사성의약품의 유용성평가)

  • Jo, Gwang Mo;Jeong, Yeong Hwan;Choi, Do Cheol;Shin, Ju Cheol
    • The Korean Journal of Nuclear Medicine Technology
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    • v.20 no.2
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    • pp.36-41
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    • 2016
  • Purpose Sentinel lymphoscintigraphy (SLS) was using only $^{99m}Tc-phytate$. If the supply is interrupted temporarily, there is no alternative radiopharmaceuticals. The aim of this study measure the particle size of radiopharmaceuticals and look for radiopharmaceuticals which can be substituted for $^{99m}Tc-phytate$. Materials and Methods The particle size of radiopharmaceuticals were analyzed by a nano-particle analyzer. This study were selected known radiopharmaceuticals to be useful particle size for SLS. We were divided into control and experimental groups using $^{99m}Tc-DPD$, $^{99m}Tc-MAG3$, $^{99m}Tc-DMSA$ with $^{99m}Tc-phytate$. For in-vivo experiment, radiopharmaceuticals were injected intradermally at both foot to perform lymphoscintigraphy. Imaging was acquired to dynamic and delayed static image and observe the inguinal lymph nodes with the naked eye. Results Particle size was measured respectively Phytate 105~255 nm (81.9%), MAG3 91~255 nm (98.7%), DPD 105~342 nm (77.3%), DMSA 164~ 342 nm (99.2%), MAA 1281~2305 nm (90.6%), DTPA 342~1106 nm (79.4%), and HDP 295~955 nm (94%). In-vivo delayed static image, inguinal lymph nodes of all experiment groups and two control groups are visible to naked eye. however, $^{99m}Tc-MAG3$ of control groups is not visible to naked eye. Conclusion We were analyzed to the particle size of the radiopharmaceuticals that are used in in-vivo. Consequently, $^{99m}Tc-DPD$, $^{99m}Tc-DMSA $are possible in an alternative radiopharmaceuticals of emergency.

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Determinants of the Location and Relocation of Domestic Logistics Firms in Korea (focused on complementary commodity flow survey for 2006) (우리나라 국내 화주기업의 입지 및 재입지 선택 특성 분석 (2006년 물류현황보완조사를 중심으로))

  • Do, Hwa-Yong;Jang, Hoon;Kim, Chan-Sung;Won, Jai-Mu
    • Journal of Korean Society of Transportation
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    • v.26 no.1
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    • pp.37-49
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    • 2008
  • In general, most of the firms do not settle down in one place for their pursuit of profit. There are many reasons for the relocation of the firms; procurement of raw material, market area, transportation cost and housing cost. The aspect of national policy, firm relocation has been systemically promoted for the purpose of logistics system efficiency. Nowadays balanced regional development has been issue. Another aspect, many countries have struggled for the preoccupancy of new place because of its production cost saving and curtailment of expenditure. The aim of this article is qualitative and quantitative analysis of relocation influence factors of domestic goods firms in Korea. This article dynamically analyzed the relocation influence factors for domestic goods firms in Korea. For the analysis this article made use of complementary survey (2006) out of the 3rd national logistics survey (2005). The complementary survey conducted pre-business district, business period, relocation reason, etc. This article dynamically analyzed from the three aspects; observation of average residence time in one business district, relocation factors, influence of market area. Analysis shows that relocation of firm is very high rate and the reasons of relocation play compositeness role. The results of determinants of location, firms approach the established market area closely and the firm's relocation is influenced by market area.

Effect of Green Tea on Tissue Distribution and Deposition of 14C-Benzo[a]pyrene in Rats (흰쥐에서 녹차의 섭취가 14C-Benzo[a]pyrene의 조직 분배 및 잔류에 미치는 영향)

  • Kim, Ju-Yeon;Noh, Sang-K.
    • Journal of the Korean Society of Food Science and Nutrition
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    • v.40 no.6
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    • pp.818-823
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    • 2011
  • Recently, we showed that green tea extract (GTE) markedly lowers the intestinal absorption of $^{14}C$-benzo[a]pyrene ($^{14}C$-BaP) and enhances its secretion into the biliary route, suggesting a protective role for GTE against body burden. These findings indicate that green tea could be used as an effective dietary means against the toxicity of BaP. The present study, therefore, was designed to investigate if green tea intake could affect the tissue distribution and deposition of $^{14}C$-BaP in rats. Male Sprague-Dawley rats had free access to a nutritionally adequate AIN-93G diet and deionized water. At ~340 g of weight, the rats were injected intraperitoneally with 27.4 kBq of [4-$^{14}C$]-BaP and 5.0 mg of BaP dissolved in $300\;{\mu}L$ of olive oil and then assigned randomly to the following two groups: one group (GTE) of rats was fed the AIN-93G diet with GTE via drinking water at approx. 4.7 mg of catechins/d, whereas the other was fed the same diet but without GTE (control). At 4 wk of dietary treatment with GTE, animals were euthanized and heart, liver, brain, spleen, kidney, retroperitoneal fat, testis, and epididymal fat were collected, weighed, and analyzed for tissue $^{14}C$-BaP. Both the control and GTE groups continuously gained weight throughout the study, but there was no significant difference between the groups. No significant differences were observed in the weights of heart, liver, brain, spleen, kidney, retroperitoneal fat, testis, and epididymal fat. However, the radioactivities of $^{14}C$-BaP, expressed in dpm/g, were significantly lower in the heart, liver, brain, spleen, and epididymal fat of rats receiving GTE as compared to their respective controls. These data indicate that green tea intake markedly lowers tissue accumulation of $^{14}C$-BaP. Taken together, these findings suggest that the decreased tissue levels of BaP by GTE intake may be associated with lowered intestinal absorption of BaP and its enhanced secretion into the bile.

Citing Behavior of Korean Scientists on Foreign Journals in KSCD (KSCD를 활용한 국내 과학기술자의 해외 학술지 인용행태 연구)

  • Kim, Byung-Kyu;Kang, Mu-Yeong;Choi, Seon-Heui;Kim, Soon-Young;You, Beom-Jong;Shin, Jae-Do
    • Journal of the Korean Society for information Management
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    • v.28 no.2
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    • pp.117-133
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    • 2011
  • There have been little comprehensive research for studying impact of foreign journals on Korean scientists. The main reason for this is because there was no extensive citation index database of domestic journals for analysis. Korea Institute of Science and Technology Information (KISTI) built the Korea Science Citation Database (KSCD), and have provided Korea Science Citation Index (KSCI) and Korea Journal Citation Reports (KJCR) services. In this article, citing behavior of Korean scientists on foreign journals was examined by using KSCD that covers Korean core journals. This research covers (1) analysis of foreign document types cited, (2) analysis of citation counts of foreign journals by subject and the ratio of citing different disciplines, (3) analysis of language and country of foreign documents cited, (4) analysis of publishers of journals and whether or not journals are listed on global citation index services and (5) analysis for current situation of subscribing to foreign electronic journals in Korea. The results of this research would be useful for establishing strategies for licensing foreign electronic journals and for information services. From this research, immediacy citation rate (average 1.46%), peak-time (average 3.9 years) and half-life (average 8 years) of cited foreign journals were identified. It was also found that Korean scientistis tend to cite journals covered in SCI(E) or SCOPUS, and 90% of cited foreign journals have been licensed by institutions in Korea.

Geological Structure of Okcheon Metamorphic Zone in the Miwon-Boeun area, Korea (미원-보은지역에서 옥천변성대의 지질구조)

  • 강지훈;이철구
    • The Journal of the Petrological Society of Korea
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    • v.11 no.3_4
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    • pp.234-249
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    • 2002
  • The Miwon-Boeun area in the central and northern part of Okcheon metamorphic zone, Korea, is composed of Okcheon Supergroup and Mesozoic Cheongju and Boeun granitoids which intruded it. The Okcheon Supergroup consists mainly of quartzite (Midongsan Formation), meta-calcareous rocks (Daehyangsan Formation, Hwajeonri Formation), meta-psammitic rocks (Unkyori Formation), meta-politic rocks (Munjuri Formation), meta-conglomeratic rocks (Hwanggangni Formation) in the study area, showing a zonal distribution of NE trend. Its' general trend is locally changed into NS to EW trend in and around high-angle fault of NS or NW trend. This study focused on deformation history of the Okcheon Supergroup, suggesting that the geological structure was formed at least by four phases of deformation. (1) The first phase of deformation occurred under ductile shear deformation of top-to-the southeast movement, forming sheath fold or A-type fold, asymmetric isoclinal fold, NW-SE trending stretching lineation. (2) The second phase of deformation took place under compression of NW-SE direction, forming subhorizontal, tight upright fold of M trend in the earlier phase, and formed semi-brittle thrust fault (Guryongsan Thrust Fault) of top-to-the southeast movement and associated snake-head fold in the later phase. (3) The third phase of deformation formed subhorizontal, open recumbent fold through gravitational or extensional collapses which might be generated from crustal thickening and gravitational instability. (4) The fourth phase of deformation formed moderately plunging, steeply inclined kink fold related to high-angle faulting, being closely connected with the local change of NE-trending regional foliation into NS to EW direction of strike in the vicinity of the high-angle fault.

A Study of Coloration of Topaz(I): Mineralogical and Chemical Study on the Topaz Selected from Some Localities of the World (토파즈의 人工着色 處理를 위한 硏究(I) : 世界 主要 産地別 토파즈의 鑛物學的 및 化學的 特性)

  • Han, Yi-Kyeong;Park, Maeng-Eon;Jang, Yong-Nam
    • Journal of the Mineralogical Society of Korea
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    • v.5 no.2
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    • pp.109-121
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    • 1992
  • For the purpose of mineralogical and chemical study on the topazes from various localities of world(Brzail, China, India, Nigeria and Sri Lanka), electron microprobe analysis(EPMA), neutron activation analysis(NAA), X-ray diffractometry, Raman spectroscopy, etch test, scanning electron microscopy, refractive index, specific gravity, fluid inclusion were performed. The chemical composition in topaz was discussed along with its physical and structural properties. Variations in the unit-cell dimension and physical properties of topaz were found to have a close relations in the unit-cell dimension and physical properties of topaz were found to have a close relationship with extent of substitution of $OH^-\;for\;F^-$. According to neutron activation analyses, the trace elements had no effects on the physical properties of topaz. Raman spectra showed that the peaks of topaz were different in intensity from one locality to another. Etching defects in topaz includes negative crystal defect o point-bottom pit(India, Nigeria) and net work defect of curl-bottom pit(Brazil, China). Fluid inclusions in topaz may be classiffied into liquid $CO_2$-bearing inclusion, gaseous inclusion, halite, sylvite-bearing inclusion and liquid inclusion. The results of this study can be useful to devising artificial coloring methods for topaz with different mineralogical compositions.

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Effects of Linoleic Acid and Serum Albumin Concentrations on Lipid Metabolism in HepG2 Cells (간세포 배양에서 Linoleic Acid와 혈청알부민의 첩가가 지질대사에 미치는 영향)

  • Cha, Jae-Young;Cho, Young-Su
    • Applied Biological Chemistry
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    • v.42 no.3
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    • pp.229-234
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    • 1999
  • The effects of linoleic acid(LA, 18 : 2) and/or bovine serum albumin(BSA) on the lipid metabolism in human hepatoma cell line HepG2 cells were evaluated. HepG2 cells were cultured in basal Dulbecco's modified Eagle's(DME) medium(Basal medium), DME medium containing 0.2 mM LA(LA medium), or DME medium containing both 0.2 mM LA and 0.2-1.0% BSA(LA+BSA medium). $[^{14}C]Acetate(0.3\;{\mu}Ci/ml\;medium)$ was added as a radioactive lipid precursor and the cells were incubated for 6 hours. An addition of LA to basal medium resulted in a decrease in the incorporation of $[^{14}C]acetate$ into total cholesterol fraction. In contrast, an addition of BSA to LA-containing medium tended to increase the incorporation of $[^{14}C]acetate$ into total cholesterol. The alteration of cholesterol metabolism in HepG2 cells incubated in LA+BSA medium was attributed by an increase in the incorporation of $[^{14}C]acetate$ into free cholesterol, but not cholesteryl ester fraction. In addition, the secretion of cholesterol was increased by LA+BSA medium, suggesting that BSA stimulates cholesterol secretion. No significant change in the incorporation of $[^{14}C]acetate$ into cellular total lipids was observed among the experimental groups. However, an increased incorporation of $[^{14}C]-labelled$ fatty acid into cellular triacylglycerol and decreased incorporation into phospholipid were observed in cells incubated with LA+BSA medium as compared to those of LA medium. The secretions of $[^{14}C]-labelled$ triacylglycerol, phospholipid, and free fatty acid were also stimulated in HepG2 cells incubated with LA+BSA medium. In conclusion, the present study suggests that in human hepatocytes, LA and BSA influence lipid metabolism, and BSA enhances the secretion of lipids.

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Effects of Dietary Quercetin on the Feed Utilization, Blood Parameters, and Meat Quality in Korean Native Goats (Quercetin의 급여가 산양의 사료이용성, 혈액상 및 육질에 미치는 영향)

  • Cho, Sung-Kyung;Jo, Cheo-Run;Jung, Sa-Mu-El;Kim, Min-Kyu;Oh, Hyun-Min;Lee, Bong-Duk;Lee, Soo-Kee
    • Journal of Animal Science and Technology
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    • v.52 no.4
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    • pp.297-304
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    • 2010
  • This study was conducted to investigate the effects of dietary quercetin on feed utilization, blood parameters, and meat quality of Korean native goats. Totally sixteen Korean native goats, 15 kg of average BW aged at 7 months, were employed in the experiment with eight replicates per treatment. One group was fed quercetin at 200 mg/kg level and the other group was fed none as control for 15 days. Dietary inclusion of quercetin did not affect feed intake, water intake, and the amount of urine and feces. Digestibilities of crude fat, NDF, and ADF for 5 days were not affected, but digestibility of crude protein was increased by the dietary inclusion of qurecetin (P<0.05). Quercetin increased rumen total VFA, propionate, and butyrate significantly (P<0.05). Acetate/propionate ratio (A/P) in the quercetin treated group was significantly higher than control. 2,2-Azinobis-(3-ethylbenzothiazoline-6-sulfonic acid) ($ABTS^+$) reducing activity of the loin from goat fed quercetin was higher than that of control. Sensory analysis conducted at 24 hr post mortem revealed that color, texture, and overall acceptability of the loin from goat fed quercetin were significantly preferred to that of control. Feeding quercetin did not influence pH, water holding capacity, 1,1-diphenyl-2-picrylhydrazyl (DPPH) radical scavenging activity, TBARS value, and fatty acid composition of the loin significantly. In conclusion, the dietary inclusion of quercetin increased the digestibility of crude protein, rumen total VFA, propionate, butyrate, and A/P ratio. In addition the higher color and texture preference and ABTS+reducing activity of loin indicating some beneficial effect on enhancement of meat qualityin goats.

Losses of Chemical Components by Infiltration Water during the Rice Cultivation at Silt Loam Paddy soil (영농기간 지하침투수에 의한 미사질양토 논의 화학성분 손실량)

  • Han, Kang-Wan;Cho, Jae-Young;Son, Jae-Gwon
    • Korean Journal of Environmental Agriculture
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    • v.17 no.3
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    • pp.268-273
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    • 1998
  • Changes of chemical component and losses of chemical fertilizer by infiltration water from 0.5ha of paddy field in Chinan area of Chonbuk province during the rice cultivation were investigated. The infiltration water samples were collected in a ceramic porous cup which was a buried at the 30, 50, 70, 90㎝ of soil depth. pH of infiltration water ranged $6.64{\sim}7.90$ and EC showed $324{\sim}647{\mu}$S/cm. The content of total-N, $NH_4-N$ and $NO_3-N$ were $0.58{\sim}14.59$, $0.05{\sim}4.25$, and $0.15{\sim}7.71mg/L$ respectively. The content of total-P and ortho-P were $0.009{\sim}0.077mg/L$ and $0{\sim}0.029mg/L$ The content of $Ca^{++}$, $Mg^{++}$, $Na^{+}$ and $K^{+}$ showed $0.88{\sim}4.78$, $0.22{\sim}1.04$, $0.17{\sim}0.98$, and $0.84{\sim}3.19㎎/L$. These all at the first transplanting are higher than that of other periods. The content of $SO_4^{2-}$ showed $3.92{\sim}18.72mg/L$ and decreased with a soil depth. However $Cl^-$ of infiltration water ranged $9.03{\sim}19.97mg/L$ and no difference with a soil depth. When infiltrated $2,416.5m^{3}$ of an infiltration water from 0.5ha of paddy field during the rice cultivation, losses of chemical components were 20.34㎏/㏊ of total-N, 3.54㎏/㏊ of $NH_4-N$, 10.44㎏/㏊ of $NO_3-N$, 0.16㎏/㏊ of total-P and 0.028㎏/㏊ of ortho-P. Also $Ca^{++}$, $Mg^{++}$, $Na^+$, $K^+$, $SO_4^{2-}$ and $Cl^-$ were lost 10.24, 2.84, 2.84, 7.22, 50.04 and 62.20㎏/㏊ respectively. There were lost by infiltration water 9.35% of nitrogen, 0.59% of phosphorous and 22.79% of potassium in applied chemical fertilizer.

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