• Journal of the Institute of Electronics and Information Engineers
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• v.51 no.12
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• pp.180-188
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• 2014

It is very important accurate diagnosis and quick treatment in cerebrovascular disease, i.e. stenosis or occlusion that could be caused by risk factors such as poor dietary habits, insufficient exercise, and obesity. Time-of-flight magnetic resonance angiography (TOF-MRA), it is well known as diagnostic method without using contrast agent for cerebrovascular disease, is the most representative and reliable technique. Nevertheless, it still has measurement errors (also known as overestimation) for length of stenosis and area of occlusion in celebral infarction that is built by accumulation and rupture of plaques generated by hemodynamic turbulence. The purpose of this study is to show clinical trial feasibility for 3D-SPACE T2, which is improved by using signal attenuation effects of fluid velocity, in diagnosis of cerebrovascular disease. To model angiostenosis, strictures of different proportions (40%, 50%, 60%, and 70%) and virtual blood stream (normal saline) of different velocities (0.19 ml/sec, 1.5 ml/sec, 2.1 ml/sec, and 2.6 ml/sec) by using dialysis were made. Cross-examinations were performed for 3D-SPACE T2 and TOF-MRA (16 times each). The accuracy of measurement for length of stenosis was compared in all experimental conditions. 3D-SPACE 2T has superiority in terms of accuracy for measurements of the length of stenosis, compared with TOF-MRA. Also, it is robust in fast blood stream and large stenosis than TOF-MRA. 3D-SPACE 2T will be promising technique to increase diagnosis accuracy in narrow complex lesions as like two cerebral small vessels with stenosis, created by hemodynamic turbulence.

• The Korea Journal of Herbology
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• v.28 no.3
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• pp.7-15
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• 2013

Objectives : Interruption and subsequent restoration of blood flow into the kidney result in renal injury. As an approach to preventing the renal injury, we determined the optimal conditions and the underlying mechanisms by which supernatant of hot water extract of ground Triticum aestivum L. (extract) attenuated ischemia/reperfusion (I/R) injury. Methods : One hour after administration of the extract (400 mg/kg) by intraperitoneal injection, renal I/R injury was generated by clamping the left renal artery in rats after surgical removal of the right kidney, followed by reperfusion. The maximal difference between the vehicle-treated and the extract-treated group under ketamine/xylazine or enflurane anesthetization was assessed at varying periods of ischemia (30-45 min) and reperfusion (3-48 hr), based on the renal function assessed with serum creatinine levels, tissue injury with hematoxylin/eosin staining, and apoptosis with terminal deoxynucleotidyltransferase-mediated dUTP nick-end labeling staining. Results : Enflurane anesthetization with 40 min of ischemia and 24 hr of reperfusion was identified to be the optimal condition, under which condition serum creatinine levels and tubular damage in the extract-treated group were significantly reduced compared with those in the vehicle-treated group ($1.3{\pm}0.2$ versus $2.7{\pm}0.3$ mg/dL, P < 0.01, and average score $1.8{\pm}0.1$ versus $3.5{\pm}0.3$, P < 0.01, respectively). These beneficial effects were mediated by inhibition of apoptotic cascades through attenuation of renal tissue malondialdehyde levels, Bax/Bcl-2 ratio and caspase-3 levels. Conclusions : The extract conferred renal protection against ischemia/reperfusion injury in rats by scavenging reactive oxygen species and consequently blocking apoptotic cascades, plausibly augmented by enflurane protection.

• Journal of Soil and Groundwater Environment
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• v.11 no.5
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• pp.1-8
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• 2006

The objective of this study is to assess impacts of sorption heterogeneity on the transport of leachate leaked from unlined landfill sites and is accomplished by examining the results from a series of Monte-Carlo simulations. For random distribution coefficient ($K_{d}$) fields with four different levels of heterogeneity ranging from homogeneous to highly heterogeneous, the transport of leachate was investigated by linking a saturated flow model with a contaminant transport model. Impacts of a chemical heterogeneity were evaluated using point statistics values such as mean, standard deviation, and coefficient of variation of the concentration obtained at monitoring wells from 100 Monte-Carlo trials. Inspection of point statistics shows that the distribution of distribution coefficient in the landfill site proves to be an important parameter in controlling leachate concentrations. In comparison to homogeneous sorption, heterogeneous $K_{d^-}$ fields produce the variability in the leachate concentration for different realizations. The variability increases significantly as the variance in the $K_{d^-}$ field and the travel time between source and monitoring well increase. These outcomes indicate that use of a constant homogeneous $K_{d}$ value for predicting the transport of leachate can result in significant error, especially when variability in $K_{d}$ is high.

• KSCE Journal of Civil and Environmental Engineering Research
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• v.40 no.6
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• pp.555-561
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• 2020

In this study, the applicability of Hunt's analytical solution for a two-layered leaky aquifer system, which was developed to estimate stream depletion due to the groundwater pumping of the upper shallow aquifer, was evaluated. The 5-year averaged stream depletions were estimated using Hunt's analytical solution for various combinations of hydraulic characteristic values such as transmissivity, storage coefficient of the two aquifers, interlayer leakage coefficient, stream-well distance, hydraulic conductivity of the streambed, and stream width. Through comparison with the numerical solution accurately simulated with a MODFLOW groundwater flow model, the analytical solution derived by regarding the stream width as a point was evaluated. It was found that the error in the stream depletion calculated by the analytical solution can be reduced to less than 0.05 when the stream-well distance is greater than the stream width or when the stream depletion factor (SDF) is more than about 3,000 days. In addition, when the streambed hydraulic conductivity is less than 1 m/d, the hydraulic diffusion coefficient of the lower aquifer layer is less than 100 ㎡/d, the hydraulic diffusion coefficient ratio of the upper and lower aquifer layers is 5 or more, and the leakage coefficient between the layers is less than 0.0004 m/d, the overall analytical solutions were overestimated compared with the numerical solutions.

• Ocean and Polar Research
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• v.28 no.4
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• pp.407-413
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• 2006

The effect of water temperature and photoperiod on the oxygen consumption of the fasted juvenile parrot fish, Oplegnathus fasciatus was investigated to provide empirical data for the early-stage culture management and bioenergetic growth model of the species. The mean body weight of the juvenile used for the experiment was $21.5{\pm}1.9g$, and the oxygen consumption rate was measured under four water temperatures (10, 15, 20 and $25^{\circ}C$) and three photoperiods (24L:0D, 12L:12D and OL:24D) with an interval of 5 minutes for 24 hours using a continuous flow-through respirometer. In each treatment three replicates were set up and 15 juveniles were totally involved. The oxygen consumption rates increased with increasing water temperature under all photoperiod treatments (P<0.001). Mean oxygen consumption rates at 10, 15, 20 and $25^{\circ}C$ ranged $202.1{\sim}403.4,\;306.7{\sim}502.2,\;536.7{\sim}791.0\;and\;879.9{\sim}1,077.4mg\;O_2\;kg^{-1}h^{-1}$, respectively. $Q_{10}$ values ranged $1.58{\sim}2.30$ between 10 and $15^{\circ}C,\;2.44{\sim}3.06$ between 15 and $20^{\circ}C\;and\;1.86{\sim}2.6y9$ between 20 and $25^{\circ}C$, respectively. Mean oxygen consumption rates of O. fasciatus were the highest in continuous light (24L:0D) followed by 12L:12D and 0L:24D (P<0.001). The oxygen consumption of fish exposed to the 12L:12D photoperiod was significantly higher during the light phase than during the dark phase under all temperature treatments (P<0.001). In summary, oxygen consumption rates of the juvenile parrot fish increase with increasing water temperature and lengthening daylight period; and, thereby, changes in water quality resulted from the depletion of oxygen under high temperature and long daylight photoperiod conditions should be monitored.

• Computers and Concrete
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• v.19 no.6
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• pp.725-736
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• 2017

This paper presents the two-, three-, and four-lane transverse reduction factor based on FEA method, probability theory, and the recently actual traffic flow data. A total of 72 composite girder bridges with various spans, number of lanes, loading mode, and bridge type are analyzed with time-varying static load FEA method by ANSYS, and the probability models of vehicle load effects at arbitrary-time point are developed. Based on these probability models, in accordance to the principle of the same exceeding probability, the multi-lane transverse reduction factor of these composite girder bridges and the relationship between the multi-lane transverse reduction factor and the span of bridge are determined. Finally, the multi-lane transverse reduction factor obtained is compared with those from AASHTO LRFD, BS5400, JTG D60 or Eurocode. The results show that the vehicle load effect at arbitrary-time point follows lognormal distribution. The two-, three-, and four-lane transverse reduction factors calculated by using FEA method and probability respectively range between 0.781 and 1.027, 0.616 and 0.795, 0.468 and 0.645. Furthermore, a correlation between the FEA and AASHTO LRFD, BS5400, JTG D60 or Eurocode transverse reduction factors is made for composite girder bridges. For the two-, three-, and four-lane bridge cases, the Eurocode code underestimated the FEA transverse reduction factors by 27%, 25% and 13%, respectively. This underestimation is more pronounced in short-span bridges. The AASHTO LRFD, BS5400 and JTG D60 codes overestimated the FEA transverse reduction factors. The FEA results highlight the importance of considering span length in determining the multi-lane transverse reduction factors when designing two-lane or more composite girder bridges. This paper will assist bridge engineers in quantifying the adjustment factors used in analyzing and designing multi-lane composite girder bridges.

• Journal of Korea Foundry Society
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• v.27 no.1
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• pp.31-35
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• 2007

In order to develop the semi-solid forming technology for magnesium alloy the rheological and thixotropic behavior of Mg alloy slurry with varying shear rates and cooling rates was investigated and simulated with considering the viscosity based on microstructures and processing variables. The viscosity of slurry of Mg alloy (AZ91D) in semi-solid region was exponentially increased with a solid fraction, and was decreased with increasing a shear rate. In order to analyze precisely the rheological behavior, the ANYCAST program modified with the Carreau model and the different heat transfer coefficient between the cast and mold was used to simulate the flow behavior of Mg semi-solid slurry during the injection into a casting mold in a high pressure diecasting machine. The simulated rheological behavior of Mg alloy slurry was matched well with the experimental results.

• Journal of Soil and Groundwater Environment
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• v.11 no.2
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• pp.45-55
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• 2006

A 2-D unconfined flow model is developed to analyze annual variations of groundwater level and bank filtration rate (BFR) for an experimental riverbank filtration site in Koryeong, Korea. Two types of boundary conditions are examined for the river boundary in the conceptual model: the static head condition that uses the average water level of the river and the dynamic cyclic condition that incorporates annual fluctuation of water level. Simulations show that the estimated BFR ranges $74.3{\sim}87.0%$ annually with the mean of 82.4% for the static head boundary condition and $52.7{\sim}98.1%$ with the mean of 78.5% for the dynamic cyclic condition. The results illustrate that the dynamic cyclic condition should be used for accurate evaluation of BFR. Simulations also show that increase of the distance between the river and the pumping wells slightly decreases BFR up to 4%, and thereby indicate that it is not a critical factor to be accounted for in designing BFR of the bank filtration system. A sensitivity analysis is performed to examine the effects of model parameters such as hydraulic conductivity and specific yield of the aquifer, recharge rate, and pumping rate. The results demonstrate that the average groundwater level and BFR are most sensitive to both the pumping rate and the recharge rate, while the water level of the pumping wells is sensitive to the hydraulic conductivity and the pumping rate.

• Journal of Korea Water Resources Association
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• v.45 no.3
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• pp.317-329
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• 2012

It is increasing to make an efforts on preventing natural river environment and preserving natural river ecosystem as development is unavoidable. In the case of inconsistent river flow caused by reservoir development, fishway is an alternative to secure fish diversity and preserve existing river ecosystem but existing fishway was established without full study for their functions. In this study, hydraulic characteristics of natural fishway established on Beakje weir's right side were analyzed. The results show that the fishway has reasonable depth and velocity condition which inhabit condition is enough for a dominant species. For assessing the optimal design of fishway, the Weighted Usable Area (WUA) was calculated by using two dimensional numerical model under the ordinary flow condition. The comparison results for various pool widths in the fishway show that the designed width has maximum WUA for adult Zacco platypus but WUA is maximized with 1m wider pool width than designed width for spawning.

• Korean Chemical Engineering Research
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• v.59 no.3
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• pp.417-428
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• 2021

The combustion characteristics of anthracite, which follow a complex process with low reactivity, must be considered through the dynamic behavior of circulating fluidized bed (CFB) boilers. In this study, computational fluid dynamics (CFD) simulation was performed to analyze the combustion characteristics of anthracite in a pilot scale 0.1 MW_th Oxy-fuel circulating fluidized bed (Oxy-CFB) boiler. The 0.1MW_th Oxy-CFB boiler is composed of combustor (0.15 m l.D., 10 m High), cyclone, return leg, and so on. To perform CFD analysis, a 3D simulation model reactor was designed and used. The anthracite used in the experiment has an average particle size of 1,070 ㎛ and a density of 2,326 kg/m³. The flow pattern of gas-solids inside the reactor according to the change of combustion environment from air combustion to oxygen combustion was investigated. At this time, it was found that the temperature distribution in air combustion and oxygen combustion showed a similar pattern, but the pressure distribution was lower in oxygen combustion. addition, since it has a higher CO₂ concentration in oxygen combustion than in air combustion, it can be expected that carbon dioxide capture will take place actively. As a result, it was confirmed that this study can contribute to the optimized design and operation of a circulating fluidized bed reactor using anthracite.