• Journal of Life Science
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• v.28 no.1
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• pp.37-42
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• 2018

Non-steroidal anti-inflammatory drug-activated gene-1 (NAG-1) is a transforming growth factor beta (TGF-${\beta}$) superfamily gene associated with pro-apoptotic and anti-tumorigenic activities. In the present study, we investigated if caffeic acid phenethyl ester (CAPE) derived from propolis could induce the expression of anti-tumorigenic gene NAG-1. Our results indicate that CAPE significantly induced NAG-1 expression in a time- and concentration-dependent manner in HCT116 cells. We also found that CAPE induced NAG-1 expression in a concentration-dependent manner in another human colorectal cancer cell line, LOVO. In addition, CAPE triggered apoptosis, which was detected with Western blot analysis using poly-(ADP-ribose) polymerase antibody. NAG-1 induction by CAPE was not dependent on transcription factor p53, which was confirmed with Western blot analysis using p53 null HCT116 cells. The luciferase assay results indicated that the new cis-elements candidates were located between -474 and -1,086 of the NAG-1 gene promoter. CAPE dramatically induced activating transcription factor 3 (ATF3) expression, but not cAMP response element-binding protein (CREB), which shares the same binding sites with ATF3. The co-transfection experiment with pCG-ATF3 and pCREB showed that only ATF3 was associated with NAG-1 up-regulation by CAPE, whereas CREB had no effect. In conclusion, the results suggest that CAPE could induce the expression of anti-tumorigenic gene NAG-1 mainly through ATF3.

• Research in Plant Disease
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• v.26 no.1
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• pp.19-28
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• 2020

Jujube witches' broom (JWB) disease is a high-risk plant disease that occurred on and devastated jujube orchards throughout South Korea in the 1950s. Recently, as the jujube cultivation area has been significantly increased nationwide, we investigated the disease in jujube orchards in the Boeun region to obtain basic information for proactively evaluating the risk of JWB outbreaks from 2017 to 2019. A field trial was conducted to evaluate the effect of the trunk injection of Sungbocycline (a. i. oxytetracycline calcium alkyl trimethyl ammonium 17%, OTC). The incidence of JWB disease was very low in Boeun, but it was gradually increased mainly in the area and on the farms where it had occurred previously. The trunk injection with OTC was most effective in the early stages of growth. However, even though the trees were treated with OTC, disease symptoms appeared in other healthy branches in severely affected trees. When the tree was first injected with OTC in June, the control efficacy of second injection was higher one month after the first injection than five months. These results suggest that early diagnosis based on various symptoms and early control based on them can be very effective in preventing JWB disease in advance and increasing control efficacy.

• Journal of the Korean Society of Radiology
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• v.5 no.2
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• pp.97-101
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• 2011

In this study, the basic research verifying possibility of applications as radiology image sensor in Digital Radiography was performed, the radiology image sensor was fabricated using double layer technique tio decrease dark current. High efficiency material in substitution for a-Se have been studied as a direct method of imaging detector in Digital Radiography to decrease dark current by using Hetero junction already used as solar cell, semiconductor. Particle-In-Binder method is used to fabricate radiology image sensor because it has a lot of advantages such as fabrication convenient, high yield, suitability for large area sensor. But high leakage current is one of main problem in PIB method. To make up for the weak points, double layer technique is used, and it is considered that high efficient digital radiation sensor can be fabricated with easy and convenient process. In this study, electrical properties such as leakage current, sensitivity is measured to evaluate double layer radiation sensor material.

• Proceedings of the KWS Conference
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• 2010.05a
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• pp.66-66
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• 2010

국내 화력발전의 $CO_2$배출량을 크게 줄이고, 친환경, 그린 화력발전시스템을 위한 가장 효과적인 수단은 발전효율을 획기적으로 증대시키는 것이기 때문에 이를 목표로 한 기술개발은 경제적으로나 산업적으로 파급효과가 매우 크다. 발전효율 증대를 위한 핵심기술은 증기터빈의 성능향상이다. 현재 일본, 미국, EU 등 각국이 가장 관심을 가지고 기술개발에 심혈을 쏟고 있는 초내열, 내식 합금소재는 $700^{\circ}C$이상에서 기계적 성능을 보장할 수 있는 Ni기 합금개발이고, 현재까지 상당한 기술수준에 이르고 있는 것으로 파악되고 있다. 국내의 경우는 관련기술개발을 위해 연구가 진행되고 있으나, 기술적으로 아직 미흡한 수준이다. Ni기 초내열, 내식합금을 개발해서 그것을 화력발전용 증기터빈 부품, 특히 초내열합금 용접형 터빈로터 소재로 이용하기 위해서는 체계적이고 실용적인 연구를 통하여 용접형로타의 내구성과 신뢰성이 보장되는 최적 수준의 접합기술 개발이 선행되어야 한다. 따라서 본 연구는 선행연구로 $700^{\circ}C$이상 초내열/내식 Ni기 합금소재의 용접기술 개발을 위한 후보 소재 Alloy 617의 동종재료 용접 기술 개발을 목표로 한다. 본 연구는 Alloy617 12.6t 맞대기 이음으로 U그루브 내로갭 TIG용접을 하였다. 1pass 1layer 방식으로 총 8pass 8layer로 용접하였다. 전류 및 용접속도는 동일하게 두고 실드가스를 Ar 또는 Ar-$H_2$ 가스로 변경하여 시험하였다. Ar가스 TIG용접은 비드표면에 산화스케일이 생기고, 비드면이 거칠며 전체적으로 산화되었다. 반면에 Ar-$H_2$가스 TIG용접은 비드표면에 산화스케일이 없으며 표면이 미려하고 산화되지 않았다. 실드가스에 수소가스 첨가시 환원성가스로 역할을 하게 되고 이에 따라 용융지 표면에 산화피막을 제거하여 용접비드를 청정하게 하는 효과를 가진다.

• Journal of the Institute of Electronics and Information Engineers
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• v.49 no.11
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• pp.47-55
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• 2012

In this paper, we propose a method to reconstruct accurate 3D shape object by using multi-view images which are disturbed by motion blur. In multi-view deblurring, more precise PSF estimation can be done by using the geometric relationship between multi-view images. The proposed method first estimates initial 2D PSFs from individual input images. Then 3D PSF candidates are projected on the input images one by one to find the best one which are mostly consistent with the initial 2D PSFs. 3D PSF consists with direction and density and it represents the 3D trajectory of object motion. 야to restore 3D shape by using multi-view images computes the similarity map and estimates the position of 3D point. The estimated 3D PSF is again projected to input images and they replaces the intial 2D PSFs which are finally used in image deblurring. Experimental result shows that the quality of image deblurring and 3D reconstruction improves significantly compared with the result when the input images are independently deblurred.

• Journal of Mushroom
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• v.18 no.3
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• pp.201-207
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• 2020

Mushrooms growing in the Wolchulsan National Park were surveyed from April to October 2018. As a result of this survey, 2 divisions, 9 classes, 24 orders, 71 families, 177 genera, and 407 species were found. Among them, 3 classes, 16 orders, 55 families, 150 genera, and 370 species belonged to Basidiomycota, while 6 classes, 8 orders, 16 families, 27 genera, and 37 species belonged to Ascomycota. The species richness was the highest in September at the altitudes between ~100 and 200 m. Among the investigated sites, the most diverse species occurred in the Gyeongpodae area. In this survey we found, Macrolepiota procera, Suillus bovinus, and Amanita pantherina, all of which have been known as climate-sensitive biological indicator species (CBIS). Based on the DNA sequence analyses, Craterellus parvogriseus was confirmed as a new record for Korea.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.19 no.6
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• pp.669-676
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• 2018

As the Moon's scientific, technological, and economic value has increased, major space agencies around the world are leading lunar exploration projects by establishing a road map to develop lunar resources and to construct a lunar base. In addition, as the lunar base construction requires huge amounts of resources from the Earth, lunar in-situ construction technology is being developed to produce construction materials from local lunar resources. On the other hand, the characteristics of lunar topography and resources vary spatially due to the crustal and volcanic activities inside the Moon as well as the solar wind and meteorites from outside the Moon. Therefore, in this paper, the geospatial analysis of lunar resource distribution was conducted to suggest regional consideration factors to apply the lunar in situ construction technologies. In addition, the lunar topographic condition to select construction sites was suggested to ensure the safe landing of a lunar lander and the easy maneuvering of a rover. The lunar topographic and resource information mainly from lunar orbiters were limited to the lunar surface with a low spatial resolution. Rover-based lunar exploration in the near future is expected to provide valuable information to develop lunar in situ construction technology and select candidate sites for lunar base construction.

• Journal of Broadcast Engineering
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• v.15 no.3
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• pp.380-390
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• 2010

The most recent standard video codec, H.264/AVC achieves significant coding efficiency by using a rate-distortion optimization(RDO). The RDO is a measurement for selecting the best mode which minimizes the Lagrangian cost among several modes. As a result, the computational complexity is increased drastically in encoder. In this paper, a method for fast intra prediction mode decision is proposed to reduce the RDO complexity. To speed up Intra$4{\times}4$ and Chroma Intra encoding, the proposed method decides the case that MPM (Most Probable Mode) is the best prediction mode. In this case, the RDO process is skipped, and only MPM is used for encoding the block in Intra$4{\times}4$. And the proposed method is also applied to the chroma Intra prediction mode in a similar way to the Intra$4{\times}4$. The experimental results show that the proposed method achieves an average encoding time saving of about 63% with negligible loss of PSNR (Peak Signal-to-Noise Ratio).

• Journal of Broadcast Engineering
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• v.13 no.3
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• pp.310-318
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• 2008

The H.264/AVC standard achieves higher coding efficiency than previous video coding standards with the rate-distortion optimization (RDO) technique which selects the best coding mode and reference frame for each macroblock. As a result, the complexity of the encoder have been significantly increased. In this paper, a fast intra-mode decision algorithm is proposed to reduce the computational load of intra-mode search, which is based on the inverse tree-structure edge prediction algorithm. First, we obtained the dominant edge for each $4{\times}4$ block from local edge information, then the RDO process is only performed by the mode which corresponds to dominant edge direction. Then, for the $8{\times}8$ (or $16{\times}16$) block stage, the dominant edge is calculated from its four $4{\times}4$ (or $16{\times}16$) blocks' dominant edges without additional calculation and the RDO process is also performed by the mode which is related to dominant edge direction. Experimental results show that proposed scheme can significantly improve the speed of the intra prediction with a negligible loss in the peak signal to noise ratio (PSNR) and a little increase of bits.

• Journal of KIISE:Software and Applications
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• v.34 no.5
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• pp.431-446
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• 2007

Executable composite Web services are selected by binding a given abstract workflow with the specific Web services that satisfy given QoS requirements. Considering the rapidly increasing number of Web services and their highly dynamic QoS environment, the fast selection of composite services is important. This paper presents a method for quality driven comosite Web services selection based on a workflow partition strategy. The proposed method partitions an abstract workflow into two sub-workflows to decrease the number of candidate services that should be considered. The QoS requirement is also decomposed for each partitioned workflow. Since the decomposition of a QoS requirement is based on heuristics, the selection might fail to find composite Web services. To avoid such a failure, the tightness of a QoS requirement is defined and a workflow is determined to be partitioned according to the tightness. A mixed integer linear programming is utilized for the efficient service selection. Experimental results show that the success rate of partitioning is above 99%. Particularly, the proposed method performs faster and selects composite services whose qualities are not significantly different (less than 5%) from the optimal one.