• Title/Summary/Keyword: 황산화 억제

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뽕잎의 기능성 효과구명

  • 김선여
    • Journal of Sericultural and Entomological Science
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    • v.41 no.S2
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    • pp.21-42
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    • 1999
  • 뽕잎의 지금까지 박ㄹ혀진 생리활성은 중금속 흡착과 해독효과, 황산화 효과, 혈중지질 억제효과 및 혈당강하 효과를 들 수 있는데, 요약하면 다음과 같다. 1) 뽕잎이 Cd과 Pb같은 중금속에 대한 흡착 및 해독작용에 미치는 영향을 조사해 본 결과, 납중독으로 인하여 감소된 Hb와 Haematocritcl가 뽕잎 투여로 증가되었고 특히 gpa합성에 관여하는 DALAD효소 활성을 증가시켰다. 또한 뇨로의 Pb의 배설 효과가 뽕잎 투여로 증진되었으며 각 조직으로의 Pb축적을 감소시켰다. Cdwndehr으로 중독시킨 흰쥐에서도 감소된 Hd와 Haematocritcl가 뽕잎투여로 증가되었고, 특히 간조직 중의 Cd축적을 61%로 감소시켜 유의성있게 감소시켰다. 또한 뽕잎투여로 인하여 변으로의 Cd의 배설효과는 38%였고 이는 녹차투여 효솨보다는 낮은 수준이었다. 2)뽕잎의 향산화 효과는 녹차와 거의 비슷하였고 특히 혐기 처리함으로써 그 활성이 증가하였다. 또한 뽕잎중의 황산화 활성 성분은 10여종 flavonoidfb 이었고 그 중 quercetin이 가장 높은 황산화 활성을 나타냈다. 특히 dlavonidfb 화합물 중 kaempferol계열의 화합뭉이 황산화 효과가 높음을 알수 있었다. 3) 뽕잎의 고지혈 억제작용에 미치는 영향을 알아본 결과 뽕잎은 혈중 총 콜레스테롤이 차지하는 비율을 보였고 특히 혈중 중성지질 함량을 감소시킴으로써 정상의 80%수준까지 회복시켰다. 또한 콜레스테롤 생합성에 관여하는 효소활성을 뽕잎의 메탄올 추출물 중 물분획뭉이 59.9%수준으로 억제시켰고 지방분해효소 활성은 유의적인 수준은 아니었지만 16% 증가시켰다. 4) 뽕잎의 혈당강하 효과는 뽕잎을 질소가스를 이용하여 혐기처리하는 경우 유의적으로 그 효과가 증강되었다. 또한 뽕잎은 대조약물인 acarbose의 10배 용량에서 대조약물보다 23% 이상의 혈당강하 효과를 나타냈다. 이들의 혈당강하 효과는 같은 농도에서 인슐린 함량을 27%회복시켰으며 특히 surcrose와 maltose와 같은 이당류를 부하시켰을 때 혈당 강하 효과는 유의적이었다. 이는 뽕잎의 혈당강화 효과는 인슐린생합성 증가에 의한 것보다는 glucosidase의 활성을 억제시키는 기전이 더 많이 관여하는 것으로 판단할수 있었다. 또한 뽕잎 중의 혈당강하 성분으로 알려진 1-deoxynojirimycin 함량은 혐기처리로 인하여 그 함량이 5%정도 증가됨을 확인할 수 있었다. 이러한 뽕잎의 생리활성 결과에 기초할 때, 뽕잎은 고지혈증을 포함한 성인병 질환의 예방과 회복에 관련되는 조절기능을 생체에 충분히 발휘할수 있는 기능성 식품의 중요한 자원으로 이용될 수 있으리라 판단된다.

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Technology for Controlling Biochemical Corrosion by Sulfur-oxidizing Bacteria of Sewage Concrete Construction applied Antimicrobial Concrete (항균 콘크리트를 적용한 정화조 및 하수처리 콘크리트 구조물의 황산화세균에 의한 생화학적 부식 저감 기술)

  • Kim, Do-Su;Khil, Bae-Su;Sohn, Yu-Shin;Lee, Seung-Hoon
    • Proceedings of the Korea Concrete Institute Conference
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    • 2008.11a
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    • pp.907-910
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    • 2008
  • Recently sewage facilities mainly consisted of concrete structures are being deteriorated seriously by biochemical reaction originated from sulfur-oxidizing bacteria. To prevent biochemical corrosion of the sewage concrete, antibiotics which inhibit growth of sulfur-oxidizing bacteria have to be developed and applied necessarily. In this study, we are going to introduce technology which biochemical corrosion of sewage facilities concrete could be controlled effectively by antibiosis of antimicrobial concrete

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A Study on the Base Properties of Nickel Type-Antifungal Agent for Reinforced Concrete Hume Pipe Lining (철근콘크리트흄관 라이닝용 니켈계 방균제의 기초적 특성 연구)

  • Jo, Young-Kug
    • Journal of the Korea Institute of Building Construction
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    • v.10 no.4
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    • pp.41-47
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    • 2010
  • It has been continuously noted that many sewage treatment concrete structures have deteriorated due to sulfur-oxidizing bacteria. There have been many reports on approaches to protecting concrete from this bacteria corrosion. The purpose of this study is to evaluate the inhibition of growth of a sulfur-oxidizing bacterium by a antifungal agent such as $NiSO_4{\cdot}6H_2O$, and the characteristics of polymer cement mortar using nickel type antifungal agent. First, we developed antifungal agents using metal nickel and $NiSO_4{\cdot}6H_2O$ to inhibit the growth of thiobacillus novellus, which is the sulfur-oxidizing bacteria in concrete. Then, ordinary cement mortar and polymer cement mortar using nickel type antifungal agent with various polymer-cement ratios, and antifungal agent content were prepared, and were tested for the antifungal adding effect, compressive and flexural strengths, expansion and leaching of nickel ion. From the test results, it was confirmed that the adding of an antifungal agent has an inhibition effect on the growth of sulfur-oxidizing bacteria at antifungal agent contents of 20 mM or more. In addition, the strengths and expansion of polymer cement mortars are not significantly changed by the addition of an antifungal agent. Therefore, the nickel-type antifungal agent developed in this study can be used to improve the durability of reinforced concrete hume pipe in the construction industry.

Effect of Wallastonite, Potssium chloride and Potassium sulphate on the mineraligation of Urea (규회석 분말, 염화칼륨 및 황산칼륨이 요소질소의 유효화에 미친 영향)

  • Oh, Wang-Keun;Kim, Jea-Yeang
    • Korean Journal of Soil Science and Fertilizer
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    • v.23 no.4
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    • pp.293-296
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    • 1990
  • The effect of wallastonite, potassium chloride and potassium sulphate on the ammonification and nitrification of urea was studied in a non-planted green house experiment, filling with 500g soil in plastic pot and incubating for 17 days. Potassium sulphate gave superior effect on the neutralizing soil acidity of wallastonite than potassium chloride and raised soil pH which promoted ammonification and subsequent nitrification of urea. Less than 20% $NO_3-N$ against the sum of $NH_4-N$ and $NO_3-N$ was accumulated in soils incubated bellow pH 6.0. It seemed that pH 5.2 to 6.0 was the critical range for the nitrification of ammonium, or raising the concentration of ammonia in soils to the toxic level to the nitrification. It appeared that the nitrification could be occuring in low moisture, air dried, conditions of soil.

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Antioxidant Activity of Ethanolic Extract of Potato(Solanum tuberlosum) (감자(Solanum tuberlosum) 에탄올 추출물의 황산화 활성)

  • Choi Eun-Mi;Koo Sung-Ja
    • Journal of the East Asian Society of Dietary Life
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    • v.14 no.5
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    • pp.479-486
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    • 2004
  • 감자는 전세계적으로 섭취되는 주요 작물로서 우리나라에서는 감자의 생즙을 관절염 및 통증을 억제하는 민간요법으로 사용되어 왔다. 본 연구에서는 감자 에탄을 추출물의 항산화 작용을 검토하였다. 감자 에탄올 추출물(0.05~5 mg/mL) 은 1,1-diphenyl-2-picrylhydrazyl radical에 대하여 강한 free radical scavenger 활성을 나타내었다. 또한 감자 추출물(0.5 mg/mL)은 쥐간 균질액 에서 생성 된 TBARS의 양을 유의적으로 억제하였으며 (p<0.05) Fe/sup 2+//ascorbate induction system에서 감자 추출물(0.5~2 mg/mL)은 DNPH 반응으로 측정된 carbonyl 형성을 억제하였다. 항산화 활성과 마찬가지로 감자 추출물의 환원력은 0.5 mg/mL 농도에서 가장 높았고 이는 α-tocopherol의 경우와 비슷하였다. 이 결과는 감자 추출물이 항산화력을 통해 생체에서 작용할 수 있는 가능성을 제시한다.

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Development on Antibiotic Concrete Mixed with Antibacterial Metals and Metallic Salts (금속 및 금속염계 항균제가 혼입된 항균 콘크리트 개발)

  • Choi, Hong-Shik;Heo, Kwon;Lee, Ho-Beom;Lee, Si-Woo;Kwak, Hong-Shin
    • Journal of the Korean Recycled Construction Resources Institute
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    • v.1 no.2
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    • pp.136-143
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    • 2013
  • In the sewage structures and wastewater facilities, concrete is exposed to hydrogen sulfide ($H_2S$) which acts as an acid material in a solution, and a strongly acidic sulfate ion ($SO{_4}^{-2}$) is generated by a sulfuric bacteria. Hence, a degradation of concrete with biochemical corrosion would be accelerated. Finally, durability of concrete and concrete structures may be greatly reduced. In this study, in order to remove the hydrogen sulfide which is used by the sulfuric bacteria organic-biologically, the antibiotic metal and metallic salt powders were mixed to concrete, and a suppressing performance of the sulfate ion was assessed. For the sulfuric acid bacteria, a comparative evaluation of antimicrobial performance on neutralized concrete specimens were carried out, also by a rapid chloride penetration test, chloride penetration depths and diffusion coefficients were measured for antibiotic concrete in accordance with the amount of metal and metallic salt-based antibacterial agents. Eventually, by an observation of the biochemical state of the surface of concrete specimens exposed outdoors, the performance and applicability of antibiotic concrete were confirmed.

Through-Si-Via(TSV) Filling of Cu with Single Additive (단일 첨가제를 이용한 관통 실리콘 비아의 구리 충진 공정 연구)

  • Jin, Sang-Hyeon;Seo, Seong-Ho;Park, Sang-U;Yu, Bong-Yeong
    • Proceedings of the Korean Institute of Surface Engineering Conference
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    • 2015.11a
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    • pp.191-191
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    • 2015
  • 반도체 소자 성능 향상을 위한 3차원 TSV배선 공정이 연구되었다. 전기도금을 이용한 TSV 공정 시 기존에는 황산 구리 수용액내에 억제제, 가속제, 평탄제등을 첨가한 복잡한 전해질이 사용되었지만 본 연구에서는 억제제만을 이용하여 Cu bottom-up filling에 성공하여 전해질의 조성을 단순화 시켰다.

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Preparation of Sulfonated Polysulfone Membranes (Sulfonated Polysulfone막의 제조 및 투과특성)

  • 김윤조;전종영;구성회;탁태문
    • Membrane Journal
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    • v.6 no.1
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    • pp.10-21
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    • 1996
  • This study is undertaken to investigate the major factor which causes a fouling phenomenon in membrane separation system and effect of hydrophilic treatment on fouling repression of hydrophobic polymer (polysulfone, PSf). Chlorosulfonic acid (CSA) and sulfuric acid as a sulfonating agents are used to produce sulfonated PSf (SPSf). SPSf membrane is prepared under several conditions to investigate it's separation process. The extent of fouling-repression is measured by membrane filtration index (MFI) value. With increasing the ion exchange capacity (I.E.C), the flux of SPSf membrane is decreased but the rejection is increased and the flux is less reduced. According to the MFI value, the SPSf membrane has a fouling-retardant effect.

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A Study on the Performance Development of Sewage Concrete by Application of Antibiotics (항균제 도포에 의한 하수시설 콘크리트의 성능향상에 관한 연구)

  • Kim, Moo-Han;Kim, Gyu-Yong;Khil, Bae-Su;Cho, Bong-Suk;Lee, Eui-Bae
    • Journal of the Korea Concrete Institute
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    • v.18 no.3 s.93
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    • pp.371-378
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    • 2006
  • Recently sewage facilities mainly consisted of concrete structures are being deteriorated seriously by biodeterioration originated from sulfur-oxidizing bacteria. In this study, to prevent biochemical corrosion of the sewer concrete, antibiotics which prevent growth of sulfur-oxidizing bacteria were developed and antimicrobial performance of it was investigated. After that, to consider applicability of antibiotics to concrete, physical properties of concrete covered with antibiotics were investigated. As a results of the study, it was proved that the antimicrobial performance of antibiotics was available. Also compressive strength and bond strength of concrete didn't closely connected with antibiotics, and resistance to abrasion, water absorption, air permeability, carbonation, salt damage and chemical attack of concrete was improved remarkably by covering with it.