• 한국약용작물학회:학술대회논문집
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• 2010.10a
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• pp.315-315
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• 2010

• Journal of Veterinary Clinics
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• v.17 no.2
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• pp.376-380
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• 2000

This study was performed to investigate the effect of activated charcoal on wound healing in an experimentally induced skin wound model. Full-thickness, skin defects ($2 cm{\times}2 cm$) were made in two different areas on the back of eight New Zealand white rabbits. Eight of 16 wounds were treated with gauze-gauze-impregnated activated charocal granules, and another eight wounds were treated with gauze-soaked saline. Wound areas were measured every other day for 2 weeks after the wound-ing. Statistical analysis was performed with the student t-test. The mean percentage of wound con- traction on the 14th day in the activated charcoal-treaded group and in the saline treated group were 93.5% and 81_7%, respectively. The mean value of tensile, strength ell the 21s1 day after wounding was,42.70{\pm}0.8 kg/5cm^2$,/TEX> in the activated charcoal-treated group and $1.75 {\pm} 0.5 kg/5 cm^2$ in the saline treated group. Significantly reduced wound area (p<0.05) and high tensile strength value (P<0.O5) were observed in activated charcoal-treated group compared with those in the saline treated group. In summary activated charcoa1 significantly reduced the wound area an increased tensile strength in the rabbit 7kin wound model. These results suggest that application of activated charcoal in skill wounds will promote wound healing.

• Applied Chemistry for Engineering
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• v.32 no.4
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• pp.385-392
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• 2021

In this study, impact of Co proportion and calcination temperature of ceria on the Co/CeO₂ was analyzed by comparing nitrogen monoxide oxidation performance of various catalysts and their physico-chemical properties. The structural properties of each catalyst were studied by XRD and BET analysis, and the surface crystal states of cobalt were proposed according to the surface density. Oxidation states of elements were observed through Raman and XPS analysis, and the relationship between typical oxidation states and nitrogen monoxide oxidation performance was designed. Through H₂-TPR, oxygen-transferring capacity due to changes in the characteristics of catalysts were identified, and activation sites (Co³⁺) for oxidation were suggested.

• Journal of IKEEE
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• v.25 no.4
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• pp.644-649
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• 2021

Self-Imitation Learning is a simple off-policy actor-critic algorithm that makes an agent find an optimal policy by using past good experiences. In case that Self-Imitation Learning is combined with reinforcement learning algorithms that have actor-critic architecture, it shows performance improvement in various game environments. However, its applications are limited to reinforcement learning algorithms that have actor-critic architecture. In this paper, we propose a method of applying Self-Imitation Learning to Deep Q-Network which is a value-based deep reinforcement learning algorithm and train it in various game environments. We also show that Self-Imitation Learning can be applied to Deep Q-Network to improve the performance of Deep Q-Network by comparing the proposed algorithm and ordinary Deep Q-Network training results.

• Korean Journal of Environmental Agriculture
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• v.20 no.4
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• pp.225-231
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• 2001

This study was conducted to find out the optimal aeration rates for minimizing odor emission and for increasing biological activities during composting of livestock manure in the enclosed bench-scale reactor system. It was treated with the mixture of poultry manure and sawdust controlled the initial water content of 60%, then aerated continuously at four different aeration rates (0.1, 0.2, 0.4 and 0.6 L/min/kg dry-solids). The average emitted concentration of ammonia in 0.6 L/min/kg dry-solids during composting reached the level of 40% in comparison with that of 0.2 L/min/kg dry-solids. In cases of sulfur compounds such as hydrogen sulfide, methylmercaptan and ethylmercaptan, their concentrations decreased with increasing aeration rates and the emission time was shortened. But they didn't detect in the treatment of 0.6 L/min/kg dry-solids. The biological activity for composting showed a trend of increasing as aeration rates increased. The treatment of 0.6 L/min/kg dry-solids gave the highest biological activity and the best compost quality.

• Journal of Life Science
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• v.25 no.9
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• pp.1072-1079
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• 2015

The lees of Korean traditional wine called as Jubak or Sul-jigemi in Korea is byproduct from alcohol fermentation industry, which is remnant of fermentation broth after filtration, centrifugation, distillation, or sedimentation during aging. Since, Korean traditional wines are produced from edible plant sources such as rice, foxtail millet, fruits and medicinal herbs with nuruk (a traditional fermentation starter and starch degrader), the Jubak from rice wine (takju), medicinal herb wine (yakju) and fruits wine are considered as safe byproduct and have various useful bioactivity. Considering the recent rapid increased production of Jubak from takju industry, and the reinforcement of dispose of Jubak as waste material in worldwide, the development of efficient reuse process for Jubak is necessary in traditional wine industry. In this review, the status of current industry, research and patent trends in relation with Jubak production, treatment, utilization and renewal was analyzed and different bioactive compounds including phenolic acids from Jubak were provided. Jubak is not any more waste material, and is the source of bioactive functional materials for food, cosmetics and medicinal industry. To develop the efficient and economic renewal technology including recovery process for bioactive substances from Jubak, systematic collaboration and research among the industry, academy and government is necessary.

• Journal of the Korea Concrete Institute
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• v.25 no.3
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• pp.261-269
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• 2013

In this study, it was developed eco-friendly inorganic binding material concrete using ground granulated blast furnace slag and alkali activator (water glass, sodium hydroxides). Eight reinforced concrete beam using inoganic binding material concrete were constructed and tested under monotonic loading. The major variables were mixture ratio of alkali activator, type of admixture and admixture. Experimental programs were carried out to improve and evaluate the flexural performance of such test specimens, such as the load-displacement, the failure mode, the maximum load carrying capacity, and ductility capacity. All the specimens were modeled in scale-down size. The eco-friendly concrete using inorganic binding material encouraged alkali activation reaction was rapidly hardening speed and showed possibility as a high strength concrete. Also, the RC beams using new materials showed similar behavior and failed similarly with RC beam used portland cement. It is thought that eco-friendly inorganic binding material concrete can be used with construction material and product as a basic research to replace cement concrete. If there is application to structures in PC member as well as production of 2nd concrete product, it could be improved the productivity and reduction of construction duration etc.

• Applied Chemistry for Engineering
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• v.29 no.5
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• pp.541-548
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• 2018

In this work, the $N_2O$ decomposition catalyst and reaction characteristics to control the $N_2O$ removal were described. Experiments were carried out by using Rh as an active metal catalyst on various supports and the $Rh/CeO_2$ catalyst with $CeO_2$ support showed the best activity for the $N_2O$ decomposition when it was prepared under the constant heat treatment condition ($500^{\circ}C$-4 hr). $H_2-TPR$ and XPS analyzes were performed to confirm the effect of the physical and chemical properties of the catalyst on $N_2O$ decomposition. As a result, it was found that the increase of the oxygen transfer capacity of the catalyst due to the increase of both the redox property and $Ce^{3+}$ amount affected the decomposition reaction of $N_2O$. In addition, the future work will include a treatment process capable of decomposition $N_2O$ and NO under the condition that $N_2O$ and NO are simultaneously generated and its characteristics of $N_2O$ decomposition reaction.

• Applied Biological Chemistry
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• v.46 no.3
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• pp.246-250
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• 2003

In order to isolate antibacterial substances from the rhizome of Zingiber mioga Roscoe, the ethanol extracts was fractionated according to the activity against Bacillus subtilis, B. cereus and Staphylococcus aureus. Three antibacterial substances were isolated and purified by column chromatography and recrystallization. Compounds I and III showed activity against all the tested bacterias and compound II exhibited the activity against B. subtilis and B. cereus S. aureus. Compound I was examined antimicrobial activity against B. subtilis, B. cereus and S. aureus by optical density using Bioscreen C. Compound I showed strong growth inhibition at 10 ppm on B. subtilis and B. cereus for 72 hrs, and at 25 ppm on S. aureus. On the basis of spectrometric studies including $1^H-NMR$, ${13}^C-NMR$, DEPT, IH-lH COSY, HMQC, HMBC and IR, compounds I, II and III were identified as $(E)-8{\beta}(17)-epoxylabd-12-ene-15,16-dial\;(C_{20}H_{30}O_3,\;MW=318)$, galanolactone $(C_{20}H_{30}O_3\;MW=318)$ and galanal A $(C_{20}H_{30}O_3,\;MW=318)$, respectively. These results are the first reports on the isolation of $(E)-8{\beta}(17)-epoxylabd-12-ene-15,16-dial, galanolactone and galanal A from the rhizome of Zingiber mioga.

• Journal of Life Science
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• v.17 no.7 s.87
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• pp.1019-1022
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• 2007

Thrombolytic therapy with tissue plasminogen activator (tPA) can improve the clinical outcome of ischemic stroke patients. However, its clinical application is limited by narrow therapeutic time windows and elevated risks of cerebral hemorrhage and brain injury. In part, these effects of tPA has been related to matrix metalloproteinase-9 (MMP-9) dysregulation. Here, we investigate that the effects of alteplase (tPA with short half-life) and pamiteplase (a modified tPA with long half-life) on the MMP-9 regulation in neurovascualr unit. The total levels of MMP-2 and MMP-9 in neuronal cells are lower than astrocytes. Alteplase (1-10 ${\mu}g/ml$) induced upregulation of MMP-2 and MMP-9 in rat cortical neurons and astrocytes, respectively. Whereas pamiteplase in a wide range of dose did not affect the MMP-2 and MMP-9 responses in both of cells. These results suggest that pamiteplase with long half-life can be provided as a agent that overcome the side effects of alteplase.