• Journal of the Society of Cosmetic Scientists of Korea
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• v.34 no.1
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• pp.51-55
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• 2008

Although phthalates aren't used as an cosmetic ingredient, some cosmetics especially nail lacquer, hair spray, and perfume still have phthalates. This is mainly caused by contamination and carryover during manufacturing process, so analysis of phthalates in those cosmetics has became a very important thing for quality-assurance(Q.A). The main phthalates under debate are diethyl phthalate(DEP), dibutyl phthalate(DBP), and bis(2-ethylhexyl) phthalate (DEHP) in domestic market. Gas chromatography-mass spectrometry(GC-MS) coupled with solvent extraction and concentration has been used for ppm level and sub ppm level analysis of phthalates. It requires much time and cost to use mass spectrometric detector and to prepare the test solution. Moreover analysis of phthalates at low concentrations is difficult because of contamination which results in wrong analytical results. In the present study, we showed a simple method using gas chromatography-flame ionization detector(GC-FID) which has fast analysis time, minimum use of solvent, reduced sample preparation steps for minimizing contamination and quantitative range of $2{\sim}50{\mu}g/g(ppm)$ in products. Consequently, this method will be proper for Q.A analysis in related companies.

• The monthly packaging world
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• s.158
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• pp.149-159
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• 2006

서울시농수산물공사 햇마늘 포장화 적극 추진/ 부산광역시 부산국제수산무역엑스포/ 경상북도청 지역중소기업 산업디자인 지원 실시/ 천안시 특산물 포장 새 디자인 개발/ 광주광역시청 디자인기업 입주 밀물/ 환경부 공공기관 1회용 종이컵 사용 줄여/ 식품의약품안전청 식품 중 알루미늄 관리(대책마련추진)/ 식품의약품안전청 유기농화장품 표시 · 단속실시/ 식품의약품안전청 국제우수안전식품전시회 개최/ 식품의약품안전청 『의약품소량포장 규정』입안 예고/ 식품의약품안전청 카페인 · 糖등 함유표시 의무화/ 식품의약품안전청 부실 의료기기 시험 기관 경고/ 식품의약품안전청 소비자 맞춤형 HACCP 제도 전개/ 산업자원부 기술표준원 국가표준(KS)제정방식 대폭 개편/ 산업자원부 기술표준원 RFID산업화 국가표준 대폭 확충/ 특허청 제1회 대학생디자인공모전 개최/

• 월간 기계설비
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• s.226
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• pp.53-57
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• 2009

그동안 많은 논란이 있었던 석면문제가 또다시 도마 위에 올랐다. 최근 아기에게 바르는 파우더를 비롯하여 화장품 등에까지 석면공포가 확산됨에 따라 환경부는 석면이 주로 건축자재(80% 이상)에 사용된 만큼 국민건강 보호를 위해 건축물에 사용된 석면의 안전한 관리가 무엇보다 중요하다고 판단, 가이드라인을 제정, 시행에 들어갔다. 가이드라인의 주요 내용은 $\Delta$건축물에 사용된 석면함유 설비 또는 자재를 조사하여 석면지도 작성 및 6개월마다 훼손 여부 평가 관리 $\Delta$석면 해체 제거작업 과정에서 석면이 비산되지 않도록 주변 대기 중 석면농도 0.01개/cc(실내공기질 권고기준) 기준 설정 $\Delta$석면 해체 제거 작업 및 폐석면 처리 시 안전한 석면관리를 위한 준수사항 등이다. 이번 가이드라인은 건축물 사용단계부터 철거 폐기까지 전 생에에 걸친 석면 관리 방법 및 기준 등을 포함하고 있어 건축물 이용자, 철거지역 인근 주민의 석면 노출 차단에 기여할 것으로 기대된다. 환경부는 가이드라인을 자치단체, 다중이용시설 관리자, 건축물 철거업체 등을 통해 널리 알리는 한편, 노동부 등 관계부처와 함께 관련제도 보완 등 건축물 석면관리 개선방안을 오는 6월까지 마련할 계획이다.

• Journal of the Korean Applied Science and Technology
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• v.38 no.6
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• pp.1568-1576
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• 2021

Here, we conducted the study on the possibility of using FK-13, a short analog of human-derived antibacterial peptide LL-37, as a cosmetic preservative to discover a natural cosmetic preservative that is safe for human body. For the purpose, FK-13 composed of 13 amino acids was synthesized by solid-phase peptide synthesis, and purified using reversed phase-high performance liquid chromatography (RP-HPLC). The purity and molecular weight were confirmed by liquid chromatography-mass spectrometry (LC-MS) analysis. FK-13 showed high antimicrobial activity on the three gram-positive bacteria (Staphylococcus aureus, Bacillus subtilis, and Staphylococcus epidermidis), the three gram-negative bacteria (Escherichia coli, Salmonella typhimurium, and Pseudomonas aeruginosa), and also even the fungus Candida glabrata. FK-13 had a broad spectrum of antibacterial activity, showing a suitability as a cosmetic preservative. In addition, FK-13 showed high thermostability and higher antibacterial activity in a comparative test with existing natural herbal cosmetic and chemical preservatives. Therefore, as FK-13 is a safe material and has high antibacterial activity at a low concentration, it is likely to be applied as a peptide natural cosmetic preservative that can replace existing chemical preservatives.

• Journal of the Society of Cosmetic Scientists of Korea
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• v.44 no.4
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• pp.363-373
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• 2018

In recent years, parabens used as preservatives in cosmetics have become a problem of human safety. Therefore, in this study, we tried to evaluate the preservative efficacy of 1,3-butylene glycol, 1,2-hexanediol, and 1,2-pentanediol as a preservative system to replace parabens. 1,3-Butylene glycol was added to cosmetic creams at a concentration of between 5 and 25%. The preservative efficacy of 1,3-butylene glycol was determined using a M-3 challenge test, as recommended by the Personal Care Products Council (formally CTFA). The alkane diols, such as 1,2-hexanediol and 1,2-pentanediol, were assessed in a similar manner. An evaluation of the preservative efficacy of 1,3-butylene glycol revealed that it was effective against all tested microbial strains at a concentration of 25%. We also investigated the efficacy of combinations of 0.3% phenoxyethanol and 0.1% ethylhexylglycerin. Finally, we tested the alkane diols, including 1,2-hexanediol and 1,2-pentanediol, as an alternative to the preservative 0.3% phenoxyethanol. Both 1% 1,2-hexanediol and 1% 1,2-pentanediol demonstrated preservative efficacy. Taken together, our study demonstrated that the formulation of 25% 1,3-butylene glycol and 0.1% ethylhexylglycerin, 1% 1,2-hexanediol, and 1% 1,2-pentanediol had the best preservative efficacy of the compositions tested. Thus, this study suggests that the formulation is a possibility of substituting parabens preservatives, which has been used in cosmetics and has become a safety issue.

• Journal of the Korean Applied Science and Technology
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• v.36 no.2
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• pp.434-447
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• 2019

Polyethylene glycol (PEG) is widely used in cosmetics as a surfactant, detergent and emulsifier. During the manufacturing process, 1,4-dioxane, which is toxic to humans, can be produced as a by-product by dimerization of ethylene oxide. As consumers' interest in cosmetic ingredients has increased, the need for safe emulsion research without PEG ingredients in the personal care market has increased. With increasing consumer interest in cosmetic ingredients, the need for safer emulsion research without the PEG ingredient in the personal care market has increased. In this study, we aimed to develop and stabilize nanoemulsion formulation without PEG. Response Surface Methodology (RSM) was used to develop optimized nanoemulsion formulations. Surfactant content (2~4%), oil content (4~8%) and polyol content (12~24%) were set as independent variables as a result of preliminary experiments for determining independent variables and ranges. The particle size, zeta potential, turbidity, and polydispersity index of the formulation were measured as response variables. As a result of measurement of the prepared nanoemulsion by FIB (Focused ion beam), spherical particles were found to have a size distribution of 100 to 200 nm. The stability of each formulation was evaluated for 30 days at each temperature ($4^{\circ}C$, $25^{\circ}C$, and $45^{\circ}C$). The optimal formulation considering the optimum particle size, turbidity, polydispersity index and zeta potential was found to be surfactant (2%), oil (8%) and polyol (24%).

• Analytical Science and Technology
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• v.28 no.3
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• pp.160-167
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• 2015

This study aims to develop a new analytical method to detect zinc pyrithione, the ingredient of cosmetics appointed as restricted ingredients and used as preservatives.. The analytical method was based on data gathered from the relevant literature. Information about the amounts of these ingredients was researched in order to select the base-matrix materials used to validate the analytical method. After selecting and preparing the base-matrix materials, the analytical method was validated by method validation procedures. The analytical method was verified first by inter-laboratory validation and then through analyzing the cosmetics sold in the market. Based on the results of this study, guidelines are proposed for the analysis of restricted ingredients in cosmetics, which will provide a method to test the cosmetics circulating in the Korean market. The use of the proposed guidelines will increase the quality of the cosmetics as well as the safety of human health, which will enhance the competitiveness of the Korean cosmetics industry and lead to an increase in the exportation of cosmetics.

• Journal of the Society of Cosmetic Scientists of Korea
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• v.42 no.4
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• pp.413-420
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• 2016

Hydroxy acid has been used to enhance anti-aging and skin moisturization by peeling effect on the skin stratum corneum, and thus it has been widely used in topical products and cosmetic products. Among them, the effect that appears most effectively in a short period of time has been reported to be effected by the pH of the cosmetic formulations. However, there are many difficulties in use due to irritation caused by pH and concerns about side effects. The purpose of this study was to evaluate the effect of applying cosmetics with (1) varying concentrations, (2) types and (3) pH of hydroxy acid on human skin. 22 healthy adults were stained with DHA (dihydroxyacetone) and DC (dansyl chloride) on the forearm, and the skin exfoliation effect was measured after application of the test products. (1) The application of GA (glycolic acid) increased the desquamation by concentration dependent. (2) the test product prepared with neutral pH showed no exfoliation effect. In contrast, SA (salicylic acid) showed a statistically significant exfoliation effect at both acidic pH and neutral pH. (3) The neutral pH SA showed excellent exfoliation effect on bot DHA and DC stained stratum corneum. These results suggest that it is possible to manufacture safe cosmetics without damaging the skin barrier, providing an opportunity to use cosmetics that are expected to exfoliate to people, whose skin is sensitive to pH.

• Journal of Convergence for Information Technology
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• v.10 no.11
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• pp.296-301
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• 2020

The purpose of this study was to verify the efficacy of cosmetics containing peptides as a cosmetic method for eyelashes. The study subjects were 21 women aged 20 years, set as the experimental group (right eyelash) and the control group (left eyelash), and measured changes according to the use of peptide cosmetics for 4 weeks. As a result of the analysis, the change in the length and density of eyelashes showed significant differences in the interaction between the group and the experiment period, and in the main effect according to each experiment period (p<.001). In the change of eyelash density and thickness, it was found that there was a significant difference at week 3 and week 4 in the difference between groups by measurement period (p>.05, p>.01). Cosmetics containing peptides have been effectively proven to be an effective cosmetic method for safe and beautiful eyelashes by increasing the length and number of eyelashes to those who suffer from side effects caused by cosmetic procedures. In the future, we look forward to expanding research to a wide range of age groups.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.17 no.1
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• pp.421-424
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• 2016

This study evaluated the efficacy and the skin safety and stability of a cosmetic that is an applied water extract and fermented hydrolysate of abalone (Haliotis discus hannai Ino), which was produced at the south coast of Korea. In the patch test, purified water, 1,3-butylene glycol and liquid crystal lotion were used as the reference group, and water extract and fermented hydrolysate of abalone and lotion formulation of water extract and fermented hydrolysate of abalone were used as the sample group. The results of patch test showed no irritation on skin among in any of the test groups. Therefore, the water extract and fermented hydrolysate of abalone (Haliotis discus hannai Ino) are safe for human skin.