• Title/Summary/Keyword: 혈연관계

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Allele Frequency of the Short Tandem Repeat(STR) Loci FFv Triplex(F13A01, FESFPS, vWA) Gene by Polymerase Chain Reaction in the Korean Population (한국인에서 중합효소 연쇄반응법에 의한 Short Tandem Repeat(STR) 유전좌위 FFv Triplex(F13A01, FESFPS, vWA) 유전자빈도 검색)

  • Yoon, Chang-Lyuk;Ryu, Geun-Chun
    • Journal of Oral Medicine and Pain
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    • v.24 no.3
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    • pp.335-345
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    • 1999
  • 법의학적 개인식별 및 친생자 감정시 여러 개의 single tandem repeats(STR) 유전좌위 검색이 필요하다. 그 이유는 STR 유전좌위는 대립유전자 수가 적고 이형접합도가 낮아 서로 다른 개체간에도 동일한 유전좌위를 가질 확률이 높기 때문에 개인식별에 대한 기여도가 떨어지게 된다. 따라서 여러 개의 다양한 STR 유전좌위들을 동시에 분석함으로써 우연적으로 개체간에 유전자형이 일치할 가능성을 낮추어야 감정의 신뢰성을 높일 수 있으며 이에는 각 STR 유전좌위에 대한 유전좌위의 분포가 인종별, 지역별로 달라 이에 대한 유전자분포를 구하는 것이 선행조건이다. 이에 본 연구에서는 법의학적 개인식별 및 친자감정시 기초자료로 활용하기 위하여 서로 혈연관계가 없는 201명의 한국인 혈액에서 DNA를 추출하여 STR 유전좌위증 human coagulation factor XIII A subunit gene(F13A0l Locus), human c-fes/fps proto-oncogene(FESFPS Locus), human von Willebrand factor gene (vWA Locus)등 FFv Triplex 유전자를 중합효소반응에 의하여 동시에 증폭하고, 폴리아크릴아마이드겔을 이용한 전기영동 및 질산은 염색을 시행한 후 FFv Triplex유전자의 유전자형 및 대립유전자 빈도 등을 분석하여 다음과 같은 결과를 얻었다. (1) F13A01유전자는 5개의 대립유전자, 12개의 유전자형을 검출하였으며, 이형접합도는 60.7%로 나타났고 대립유전자 및 유전자빈도는 3.2, 4, 5, 6, 16 대립유전자에서 각각 0.34 3, 0.114, 0.062, 0.475, 0.005로 나타났으며, 대립유전자 7, 8, 9, 10, 11, 12, 13, 14, 15는 검출되지 않았다. (2) F13A01 대립유전자다양성 (allelic diversity value)은 0.641, 개인식별력(PD)은 0.814를 보였으며 대립유전자다양성 및 이형접합도가 다른 민족과 비교할 때 다소 낮았다. (3) FESFPS유전자는 8개 대립유전자 모두 나타났으며, 15개의 유전자형을 검출하였으며, 이형접합도는 66.7%로 나타났고 대립유전자 및 유전자빈도는 7, 8, 9, 10, 11, 11, 12, 13, 14 대립유전자에서 각각 0.002, 0.002, 0.005, 0.032, 0.507, 0.264, 0.197, 0.007로 나나났다. (4) FESFPS 대립유전자다양성(allelic diversity value)은 0.641, 개인식별력(PD)은 0.804를 보였다. (5) vWA유전자는 9개의 대립유전자, 23개의 유전자형을 검출하였으며, 이형접합도는 80.1%로 나타났고 대립유전자 및 유전자 빈도는 11, 12, 14, 15, 16, 17, 18, 19, 20 대립유전자 에서 각각 0.002, 0.002, 0.219, 0.032, 0.187, 0.279, 0.189, 0.072, 0.017로 나타났으며, 대립 유전자 13, 21는 검출되지 않았다. (6) vWA 대립유전자다양성(allelic diversity value)은 0.799, 개인식별력(PD)은 0.924로 매우 높게 나타냈다.

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Genetic Parameter Estimates for Productive Traits in Duroc Pigs (듀록종의 산육형질에 대한 유전모수 추정)

  • Cho, Chung-Il;Choy, Yun-Ho;Choi, Jae-Kwan;Choi, Tae-Jeong;Lee, Seung-Su;Cho, Kwang-Hyun;Park, Byoung-Ho
    • Journal of agriculture & life science
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    • v.46 no.5
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    • pp.57-63
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    • 2012
  • The purpose of this study was to estimate genetic parameters for productive traits in Duroc breed. In this study, 40,657 records for productive traits and the pedigree data of 47,974 families were collected from 41 farms registered at the Korean Animal Improvement Association (KAIA) from 2004 to 2011. The REMLf90 program was used to analyze a multiple traits animal model with fixed effects of sex, contemporary group, parity and age at the end of the test as covariate and random effects of animal and residual error. The heritabilities of days to 90 kg (D90KG), average daily gain (ADG), backfat thickness (BF) and eye muscle areas (EMA) were estimated to be 0.334, 0.340, 0.335, and 0.200, respectively. The genetic correlation coefficients were -0.992 between D90KG and ADG, -0.142 between ADG and BF, -0.361 between ADG and EMA, and -0.243 between BF and EMA. Conversely, positive genetic correlations for D90KG with BF and EMA were 0.13 and 0.36, respectively.

How Korean children and adolescents perceive their parents: Indigenous psychological analysis (아동과 청소년의 부모에 대한 지각: 토착심리학적 접근)

  • Young-Shin Park;Uichol Kim;Kee Hye Han
    • Korean Journal of Culture and Social Issue
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    • v.9 no.2
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    • pp.127-164
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    • 2003
  • This study investigates how Korean children and adolescents perceive their parents using the indigenous psychological approach. An open-ended questionnaire was developed by the first two authors to investigate reasons why children and adolescents feel grateful, respect, indebted, close, conflict, and distance with their parents. A total of 763 participants (212 grade three students, 267 grade eight students, and 284 grade eleven students) completed the questionnaire. The results can be summarized into three main points. First, the vast majority of children and adolescents feel grateful, respect, and indebted to their parents. They feel grateful, respect and indebted for the sacrifice and suffering they experience looking after the family. Moreover, they respects their parents because of their sincerity, blood relationship, benevolence, guidance and educational support. They feel indebted since they did not obey them, were not able to meet their expectations, and were not diligent in their schoolwork. They felt especially close to their mother. The conflict they felt was due to generational gap and in their academic performance. Second, age affects how they perceive their parents. The parent-child conflict increases with age. The feeling of indebtedness also increase with age. However, the feeling of gratefulness and respects decreases with age. The feeling of closeness with father also decreases with age. Third, socio-economic status and educational achievement of children and adolescent affect the perception of their parents. Those with higher academic grade and socio-economic status are more likely to feel respect and indebtedness and less likely to feel conflict and distance.

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Blockchain Technology and the Creation of Trust : Focusing on Transparency, Immutability and Availability

  • Kim, Kee-Joo;Lee, Myung-Suk
    • Journal of the Korea Society of Computer and Information
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    • v.27 no.3
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    • pp.79-90
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    • 2022
  • 'Trust' is 'believing and relying on people or things', and at the same time, it is the foundation and essential condition of existence of a specific community or society. How blockchain technology creates trust can be found in the fact that it is a technology shared by all participants. As a shared technology, blockchain itself shows three characteristics: transparency, immutability, and availability. Because it is shared, it is transparent, and because it is shared, it is immutable, which is difficult to modify or delete. In addition, since it is shared, the entire system operates normally even if some failure occurs. The significance of trust created based on this blockchain technology can be summarized in three aspects as follows. The first is to understand the problem of trust in connection with technology. Second, understanding the relationship between information and trust begins to pay attention. Third, based on the expanded information processing capability, it is possible to establish a large-scale, concrete relationship without central mediation.

A Basic Study on Spatial Recognition through Poet in Soswaewon Garden (시문을 통해 본 소쇄원의 공간인식에 관한 기초연구)

  • Lee, Won-Ho;Kim, Dong-Hyun
    • Journal of the Korean Institute of Traditional Landscape Architecture
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    • v.33 no.3
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    • pp.38-49
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    • 2015
  • This study aims to contemplated spatial recognition in Soswaewon Garden through garden visitors poetry. It was content analysis in poetry and extract frequency from words based on relationship of author. The results were as follows. First, relationship of authors who wrote Soswaewon Garden poetry was formed in companionship. In the Yang, San-Bo(梁山甫), poetry was written by Song, Soon(宋純), Kim, Un-Geo(金彦据) and Kim, In-Hu(金麟厚) as the central figure. Especially Kim, In-Hu was playing an important role in Soswaewon Garden poetry. He was wrote many of poetry and keep friends with Yang, Ja-Jeong(梁子渟) too. In the Yang, Ja-Jung, relationship of previous generation was sustained. In addition, Ko, Gyeong-Myeong(高敬命) and Kim, Seong-Won and Jeong, Chul(鄭澈) is more closely related than others. Because blood relationship by marriage. In the Yang, Jin-Tae(梁晋泰), He formed a relationship with a celebrity and attend to international activity. Since then Yang, Jin-Tae periord, Yang, Gyeong-Ji(梁敬之) and Yang, Chae-Ji(梁采之) formed relationship of previous generation was sustained. And surrounding people was written poetry as hold a banquet. Second, plant and ornament is a popular object for writing poetry. Bamboo grove and Fine tree with a high frequency of plant element in poetry. Bamboo grove is a typical species of trees in Soswaewon Garden. It was enclosed the Soswaewon Garden. Fine tree was often used target of poetry as a single tree. Meanwhile, ornament of the wall has been used most frequently. Descendants wrote a poem to see it because Kim, In-Hu's poetry was left. This phenomenon is involves respect for the ancient sages with high frequency. In addition, behavior of viewing the landscape was mainly appeared. Third, spatial recognition of Soswaewon Garden can be divided into landscape cognition, behavior cognition and emotional cognition. In a aspect of landscape cognition, early Soswaewon Garden was recognized as a pavilion. That was used garden name to 'Soswaewon Garden' since Yang, Ja-Jung's period. That is to say, Soswaewon Garden expanded from pavilion area surrounded by trees into the whole appearance is equipped garden area. Behavior cognition was consisting drink and enjoys a landscape. In the Yang, San-Bo, authors enjoyed drinking and viewing a landscape besides walking, writing poetry, viewing the moon. But after Yang, San-Bo's period other than drinking and enjoy a landscape has appeared a low frequency. These results were changed from internal place to blood relationship into external place to companionship. In the Yang, San-Bo's emotional cognition was sorrow and yearning about leave to Soswaewon Garden with an idly atmosphere. Pleasant emotion was sustained all generation. And emotion of respect for the ancient sages was appeared since Yang, Cheon-un.

Korean Children with Infantile Pompe Disease Presenting with Hypertrophic Cardiomyopathy: Experiences in a Single Institution (단일 기관에서 경험한 비후성 심근병증으로 발현된 영아형 폼페병)

  • Ko, Jung Min;Lee, Young Ah;Kim, Gi Beom;Park, Sung Sup;Song, Jung-Han
    • Journal of The Korean Society of Inherited Metabolic disease
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    • v.12 no.1
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    • pp.42-48
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    • 2012
  • Pompe disease is a rare lysosomal glycogen storage disorder caused by a total or partial deficiency of the acid ${\alpha}$-glucosidase (GAA) enzyme due to the GAA gene mutations. The classic infantile form of Pompe disease is a rapidly progressive multi-organ disease with hypotonia, generalized muscle weakness, and hypertrophic cardiomyopathy, usually leading to death in the first 2 years of life. Enzyme replacement therapy with recombinant human GAA has been shown to be effective and subsequently yielded promising results. Here, we present clinical and genetic characteristics of three Korean non-classic infantile Pompe patients, and the short term efficacy of enzyme replacement therapy. Considering that enzyme replacement therapy can change the natural course of infantile Pompe disease, early diagnosis and early initiation of treatment is critical to improving patient outcomes.

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The Feminism Narrative in TV Drama : Breaking the Cliché and Overturning the Order of the Patriarchy (TV드라마 <마인>의 여성주의 서사 - 가부장제 클리셰의 파기와 질서의 전복 -)

  • Kim, Mi-Ra
    • The Journal of the Korea Contents Association
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    • v.21 no.11
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    • pp.268-280
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    • 2021
  • This study analysed the narrative strategies in TV drama utilized in order to support the recent feminism movements. The analysis revealed that this TV drama breaks away from the clichéd patriarchal drama series. It portrays the main characters are not the sons but the two daughters-in-law, and represents the women challenging the order of the patriarchy, and resolving the issues. In this drama, men's power was removed and female agents were held up to ridicule. In addition, it eradicates the traditional female conflict structures and creates a strong bond between the females. With this storyline, TV series concludes with two achievements. One, the stepmother and the mother co-parent the child instead of the father, suggests that a non-blood related matriarchal family is possible. Two, the heir to the chaebol family, which is traditionally a patrilineal structure, is not the oldest son or the immoral son, but the lesbian daughter-in-law, overturning the idea of heteronormativity that is dominant in the patriarchal system.

Study on gatekeeping in selecting process of people in the news: Based on Social Capital theory (인물뉴스의 특성과 결정요인 연구: 사회자본(Social Capital) 이론을 중심으로)

  • Lee, Wan-Soo
    • Korean journal of communication and information
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    • v.32
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    • pp.295-332
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    • 2006
  • This study inquires at behavior and attitude of gatekeepers at major Korean media in the process of selecting and covering newsmakers, with focusing on factors, paths and practices in making news on the people. The study assumes that gatekeepers' social networking process with social elites, based on birth places, alma mater and kinship, plays great role in making people in the news. The study applies methods of in-depth interviews with people-page gatekeepers and content analysis of news on newsmakers. The in-depth interviews and content analysis unveil that people-page gatekeepers tend to support high society and social elite group. Furthermore, through the process of news-making, the gatekeeper group shares social capital such as economic exchanges and socio-political influences with social elite group. The result of interviews and analysis confirm that social networking based on personal affiliation plays as an important factor in selecting and covering newsmakers. With in-depth analysis of news contents, the study finds out that social elite groups of top government officials, corporate CEOs, medical doctors, lawyers, judges, prosecutors, college professors, cultural celebrities and journalists, who are predominantly male, appear on people pages much frequently out of proportion. The content analysis also reveal that 'personal news,' which cover personal and private life or unilaterally promote newsmakers predominate in terms of frequency and amount over socially-important or pubic-interested 'public news.' In terms of news values, fragmentary news composed of sensational, personal and gossiping elements appear more frequently than socially-meaningful news with strong social issues and public messages.

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A Research on the Character Modification in Animation Storytelling : Comparative Analysis on (스토리텔링 내부의 캐릭터 변용에 관한 연구 : )

  • Kwon, Jae-Woong
    • Cartoon and Animation Studies
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    • s.25
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    • pp.1-39
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    • 2011
  • It is important to create animation storytelling because it is the most critical factor to make animation successful at the box-office. As such, lots of researchers have paid attention to Disney's animations because the Walt Disney company has produced the largest number of interesting animations. One of Disney's strategies to make story interesting is the application of original works that were already open to public. On this point, this article explores how Disney deals with characters in its animation that is based on an original work. Drawing a comparison between characters of and those of "Hua Mulan", which is its original work, this article focuses on how characters are created and used for the purpose of managing animation storytelling. Significant differences between two works exist. That is to say, actively makes the use of characters. First, it creates several new characters that are not seen in "Hua Mulan." Those characters can be divided into three groups by their roles; realistic characters, unrealistic characters, and realistic characters of unrealistic personalities. Second, Mulan in has both masculine initiative and feminine adaptability, and each one is used as necessary through the whole narrative. Last, it sets up a relationship between characters either in a blood-based family category or in a social category. Through these results, it is possible to confirm that this modification of characters is solely to manage the narrative with more flexibility.

The Concept of Continuity in Confucianism through filial piety(孝) Ethics (효(孝) 윤리를 통해 본 유가(儒家)의 연속적 사유)

  • Lee, Cheon-Sung
    • The Journal of Korean Philosophical History
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    • no.29
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    • pp.179-202
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    • 2010
  • In addition to the emphasis on filial piety ethics in everyday life, filial piety obtained a further significance in Confucianism which had the strong sense of ancestor worship. This paper focuses on filial piety as a mechanism of continuity within Confucianism and points out that it owed its development to its connection to agricultural culture. The sedentary life with less mobility forged a relative intimacy among people and filial piety was the actual expression of that kind of intimate affection. Yet, filial piety in Confucianism created a unique culture in terms that it not only stipulated material and emotional support for parents but also expected one's piety to the further ancestors through a memorial service and made its connection to the infinite posterity through sons. From the perspective of Confucianism that established filial piety at the turning point from life to death, the self existing in present was not an isolated self anymore. Yet, one can see another characteristic of Confucianism from that filial piety, based on blood bonds, could move beyond paternalism to broaden itself. It could be expanded to the care for strangers. The aged experience and wisdom through agricultural life begot the insight that the nature made its infinite connections with everything through circulation. As a stone thrown in a pond would enlarge its boundary by drawing larger and larger concentric circles, this thought enabled people to enlarge their affection to their parents to universal humanity. In this enlarged network, though it was natural to make distinctions between the closer and the farther, Confucianism sought to overcome it by establishing oneself upright. Confucianism emphasized the moral cultivation with its filial piety concept that contained the diachronic thought penetrating life and death and the broadened perspective relating everything around. In Confucianism, filial piety provided an important medium in forming a moral subject that penetrated life and death and related self and others. Inherent in it is the Confucius thought of continuity that searched for a paragon of a moral human being regardless of time and space.