• Korean Journal of Poultry Science
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• v.42 no.4
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• pp.307-314
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• 2015

The study was carried out to investigate the effects of by-products of herbal medicines on performance, enteric microflora and blood biochemical profiles and immunological parameters in broiler chicks. A total of ninety-six, 3-d-old birds were assigned to a basal diet (CON) or a basal diet supplemented with 0.15 % (HM1), 0.3% (HM2) or 0.5% (HM3) by-products of herbal medicines. There was a significantly (p<0.05) improved feed conversion ratio (FCR) in birds fed diet supplemented with 0.15% by-products of herbal medicines (HM1) compared with the control birds during starter period (3~21 days). However, no difference in body weight, feed intake, total gain and FCR among treatment groups was observed during the entire feeding period (3~35 days). The colony forming units (CFU) of E. coli and Lactobacilli in the digesta of ileo-cecum was not also affected by dietary treatment. Serum AST (aspartate aminotransferase) and glucose decreased (p<0.05) in birds fed diets supplemented with herbal medicines compared with those fed the basal diet. In particular, the birds fed diets supplemented with herbal medicines showed a significant (p<0.05) increase in blood mean corpuscular volume (MCV) level compared with the control birds. However, the most of blood biochemical and hematological parameters and immunoglobulins (IgG and IgA) were not affected by the dietary treatment. In conclusion, the low level of dietary herbal medicines showed beneficial effects on FCR during starter period and liver functions, suggesting that by-products of herbal medicines may be applicable as functional feed additives in birds.

• Journal of Veterinary Clinics
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• v.30 no.5
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• pp.353-358
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• 2013

A study investigated the effects of Galla Rhois (GR) on growth performance and diarrhea incidence of postweaning piglets. One hundred 28-day-old piglets were randomly assigned into five experimental groups, which were a basal diet alone (NC), chlortetracycline 0.3 g/kg feed (PC) and supplemented with GR 1.0 g/kg feed (GR 1), GR 2.0 g/kg feed (GR 2), and GR 4.0 g/kg feed (GR 3). After 28 days of administration, final body weight (BW) and feed conversion ratio of PC, GR 2 and GR 3 was significantly different compared to those of NC (p < 0.05). Additionally, the average daily gain (ADG) and average daily feed intake (ADFI) of PC and all groups treated with GR was significantly different compared to those of NC (p < 0.05). Especially, final BW, ADG, ADFI and feed conversion ratio (FCR) of GR 2 and GR 3 were not significant different compared to those of PC. In fecal scores and duration of diarrhea, PC and all groups treated with GR were significantly different compared to NC (p < 0.05). In hematogolical and serum biochemical analysis, there were no significant differences in any of the hematogolical and serum biochemical parameters examined in either NC or all groups treated with GR. The results of this study indicated that GR could be a potential candidate as feed additives for the improvement of growth performance and incidence of diarrhea in piglets.

• Clinical and Experimental Pediatrics
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• v.52 no.2
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• pp.167-175
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• 2009

Purpose : This study has been conducted to analyze whether the biochemical nutrition indexes might be useful and effective for evaluating the nutrition states of children. Methods : We evaluated 269 children, aged 3-9 years old, who had visited Gangneung Asan Hospital for elective surgery from January 2006 to December 2007, and examined their anthropometric and preoperative laboratory data with retrospective analysis. The children were classified into underweight, normal weight, overweight, and obese groups according to body mass index (BMI). The biochemical nutrition indexes (total lymphocyte count (TLC), hemoglobin, hematocrit, serum albumin, cholesterol, et al) of each group were then analyzed statistically. Results : None of the groups showed statistically significant differences in TLC. Serum albumin decreased significantly in the underweight group. Red blood cell (RBC) count, hemoglobin, hematocrit, and serum total cholesterol in the obese group were higher than in the normal weight group. None of the groups showed statistically significant increase in mean corpuscular volume or mean corpuscular hemoglobin, and it seems that the increase of hemoglobin and RBC count in the overweight and obese groups is due to the enhancement of erythropoiesis rather than iron metabolism. However, in females, almost all nutrition indexes except albumin were statistically significantly poor. Conclusion : Serum albumin, total cholesterol, RBC count, hemoglobin, and hematocrit were useful as nutrition indexes. However, except for albumin, these indexes were significantly poor for females. More control studies are needed to confirm the effectiveness of biochemical indexes for evaluating the nutritional state of children.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.11 no.12
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• pp.4843-4853
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• 2010

The purpose of this study was to investigate the association of blood pressures, hematological and biochemical properties of blood according to the degree of obesity in health checkup examinees. Study subjects were 3,731 adults of 20 years and over (2,312 males, 1,419 females), who underwent health package check-up at the Korea Health Management Association from Jan. 2007 to Dec. 2009. As a result, the rates according to the degree of obesity of study subjects were 4.6% in low weight group, 44.3% in normal weight group, 25.0% in over weight group and 26.1% in obesity group. The over weight group were significantly higher in 40's age group than other groups, and the obesity group were significantly higher in 50's age group than other groups. The abnormal rates of SBP, DBP, TG, TC, HDL-C, LDL-C, ALT, AST in male were significantly higher than that of female. With respect to degree of BMI, the abnormal rates of SBP, DBP, TG, TC, HDL-C, LDL-C, ALT, AST, GGT, ALP were significantly increased with higher level of BMI. The age-adjusted odds ratio in the abnormal level of SBP, DBP, TG, TC, HDL-C, LDL-C, AST, ALT and GGT were significantly increased in overweight group and obese group than that of normal weight group.

• Korean Journal of Environmental Agriculture
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• v.31 no.3
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• pp.264-270
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• 2012

BACKGROUND: The purpose of this study was that serum metabolic and hematological variables were measured to investigate the detoxication effect of Taraxacum mongolicum extract on male albino rat exposed with lead and mercury. METHODS AND RESULTS: For this study, Pb and Hg-exposed( 50 ppm) albino rats was used, and the treatments were carried out in three doses of 100 mg/kg, 200 mg/kg and 500 mg/kg as dry weight of T. mongolicum extract. T. mongolicum extract could improved the body weight gain and feed efficiency ratio, except to food intake. The levels of biochemical factors elevated by Pb-Hg mix exposure, which are Bilirubin, Alkaline phosphatase(ALP), glutamic oxaloacetate transaminase(GOT), glutamic pyruvate transaminase (GPT), lactate dehydrogenase(LDH), ceatinine and blood urea nitrogen(BUN), were significantly reduced in all treated groups as compared to Pb-Hg mix exposure alone. T. mongolicum extract was shown to suppress the accumulation of Hg and Pb in serum by dose dependent manner. CONCLUSION: Therefore, this study suggest that T. mongolicum extract might have the potential effect to minimize the toxic effects of Pb and Hg.

• The Journal of the Convergence on Culture Technology
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• v.6 no.4
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• pp.253-258
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• 2020

Depression is a disease with an increasing prevalence worldwide, and is highly associated with mortality as well as several diseases such as hypertension. The aim of this study is to discover clinical risk indicators associated with depression in the occupational group of simple labor workers. This study used the Seventh Korean National Health and Nutrition Examination Survey (2016-2018) conducted by the Korea Centers for Disease Control and Prevention. In association between depression and demographic information, age, sex, degree of stress perception, and stress perception ratio indices had a very high statistical association with depression, and education level and marital status were also associated with depression. Obesity indices such as abdominal circumference and body mass index were not associated with depression. Among the blood information, hemoglobin and hematocrit were highly associated with depression, and statistical significance was maintained even in the analysis adjusted for sex and age. The results of this study can be used as information for the prevention and treatment of depression in the occupational group of simple labor workers in the future.

• Journal of Digital Convergence
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• v.11 no.10
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• pp.493-505
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• 2013

We investigated the effect of red ginseng extracts on blood biochemical parameters, bone density and bone inorganic components etc. and data were analyzed by one-way ANOVA and Post-Hoc Test. In the results of our study, the level of albumin and HDL, Ca, P, Mg, and estradiol in blood, and the content of Ca, P, ash in femur were significantly increased in red ginseng treated group than in OVX group, and the level of ALP, AST, ALT, blood glucose, total cholesterol, triglyceride, LDL, creatinine, osteocalcin, and N-terminal telopeptide were significantly decreased in red ginseng treated group than in OVX group (p < 0.01). From these results, we knew that within the normal level, red ginseng extracts improved liver and kidney function, component of glucose and lipid in blood, bone density, bone ash and inorganic components in femur, and index related with bone metabolism.

• Journal of Food Hygiene and Safety
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• v.33 no.3
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• pp.214-219
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• 2018

The present study was carried out to investigate the acute oral toxicity of Chamaecyparis obtusa (C. obtusa) essential oil in ICR male and female mice. Acute oral treatment with C. obtusa essential oil did not reveal any sign of toxicity or mortality in treated mice. Mouse body weights were not affected after single oral administration of C. obtusa essential oil during the 14-day observation period. In the hematological and blood biochemical analysis, all parameters of the treated group with 2,000 mg/kg body weight of the essential oil were not significantly different those of the control group. Therefore, the lethal dose 50 of the essential oil was estimated to be greater than 2,000 mg/kg body weight in mice, which indicated that the essential oil is non-toxic. In conclusion, this study suggests that C. obtusa essential oil orally safe ICR mice.

• Korean Journal of Fisheries and Aquatic Sciences
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• v.30 no.4
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• pp.601-607
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• 1997

This study was designed to investigate the biochemical pollutant marker for diagnosis of marine pollutions by the changes in lipid components of the flounder (Pleuronichthys cornutus) in the Yellow Sea of Korea. Hemoglobin levels in serum of wild flounders in the yellow Sea were significantly lower $(15\~30\%)$ than those of wild flounder in Pohang (control) of the East Sea. Triglyceride (TG) contents in serum of wild flounders in the Yellow Sea were higher $(15\~50\%)$ than those of wild flounder in Pohang. Total and low density lipoprotein (LDL)-cholesterol contents in serum of flounders in the Yellow Sea were significantly higher $(20\~25\%\;and\;15\~35\%,\;respectively)$ than those of wild flounder in Pohang. Atherogenic index (Al) in serum of wild flounders in the Yellow Sea were significantly higher $(10\~60\%)$ than these of wild flounder in Pohang but T-Chol/PL ratios showed almost no change in serum of flounders in the Yellow Sea we examined. These results suggest that near-coastal water as well as neritic water of the Yellow Sea might be affected by pollutant input.

• Korean Journal of Fisheries and Aquatic Sciences
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• v.32 no.1
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• pp.37-41
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• 1999

This study was designed as a part of efforts to investigate the biochemical pollutant markers for diagnosis of marine pollutions by changes in cholinesterase activity of the flounder (Paralichthys olivaceus) in tie South Sea of Korea. Aceflcholinesterase (AChE) activities in brain and muscle of cultured flounders in the South Sea were significantly lower ($10\~20\%$ and $12\~19\%$, respectively) than those of wild flounder in Pohang of the East Sea as a control. Buthrylcholinesterase (BChE) activites in brain and muscle of cultured flounders in the South Sea were also remarkably lower ($25\~40\%$ and $22\~35\%$, respectively) than those of wild flounder in Pohang. Lactate dehydrogenase (LDH) activites in serum of cultured flounders in South Sea were significantly higher ($10\~55\%$) than those of wild flounder in Pohang. It suggests that AChE, BChE and LDH activities of the flounders clould be used as effective biochemical markers for early warning of environmental damages caused by organophosphorus pesticides.