• Korean Journal of Adult Nursing
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• v.15 no.1
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• pp.14-21
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• 2003

Purpose: The purpose of this study is to determine the level of pain related to a blood sugar test. Specifically, the study attempts to compare the varying degree of pains when different types of blood sugar test are used. Method: A sample of 56 subjects is composed of DM patients admitted to a medical ward of C university hospital in Gwangju. Data were collected from July, 2001 to December, 2001. The blood sugar tests were administered in four different ways: (1) the use of 27G needle only, (2) the use of 27G needle followed by ice-packed treatment, (3) the use of 27G needle after EMLA cream application, and (4) the use of lancet. The degree of pain is measured with a visual analogue scale and performed twice. Result: In both measures, the use of 27G needle only method is shown to cause the highest level of pain in comparison with the rest of methods (F=4.01, p=.01; F=8.14, p=.00). However, the differences in pain between time in all methods were not found to be significant (t=-.85, p=.40; t=.80, p=.42; t=.31, p=.75; t=.19, p=.85). Conclusion: The study results indicate that the method using lanceter is more recommendable than the use of 27G needle only method. Further research is needed to support the current study result with the use of different measurement scales and to determine effective methods of blood sugar test to lower pain and compliance.

• The Journal of Korean Academic Society of Nursing Education
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• v.12 no.2
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• pp.265-271
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• 2006

Purpose: To analyze the newly developed vacuum assisted auto-lancing technique applied to the forearm for the purpose of obtaining an adequate blood sample for glucose test with minimal pain. Methods: Visual and facial pain measures were introduced to compare lancing pain between the forearm and fingertip in 58 normal females. Sampled blood volumes were accurately measured by computer scanning technique. Results: Visual pain measure demonstrated significant pain reduction effect of the forearm sampling compared with the traditional fingertip sampling, which was also consistent with facial pain measure results. Blood volume more than $0.5{\mu}L$, enough for blood glucose testing with modern glucometers, was collected in 399(86%) of 464 forearm samples. Conclusions: Capillary blood sampling could be performed with minimal pain on the forearm by the newly developed vacuum assisted auto-lancing technique. With some resampling when necessary, the forearm sampling seemed very useful, considering almost no pain felt by the patients.

• Journal of the Korea Convergence Society
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• v.10 no.11
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• pp.501-510
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• 2019

This study aimed to find health related lifestyle factors that influence glycemic control for diabetes mellitus (DM) management strategies. This study used nested case-control design with matching variables that were not controlled by individuals such as age, sex, insulin or oral hypoglycemic agent (OHA) use, disease duration, education level and household income. This study analyzed 983 subjects with type 2 DM who enrolled in the $7^{th}$ (2016-2017) Korean National Health and Nutrition Examination Survey (KNHANES). The target HbA1c level of controlled glucose was defined as less than 6.5%, and 289 (30%) were achieved. Conditional multivariable logistic regression analysis was performed to find self-control factors associated with HbA1c levels. The results statistically significant for variables such as duration of diabetes, insulin or OHA use in overall cohort and body mass index (BMI), smoking and fundus Examination in matched cohort. These results are expected to provide as evidence for the intensive care criteria(disease duration, drug use) and lifestyle management strategy(BMI, smoking, fundus examination).

• Clinical and Experimental Pediatrics
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• v.49 no.6
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• pp.665-671
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• 2006

Purpose : To study the effects of growth hormone(GH) treatment on glucose metabolism and insulin resistance in children with idiopathic short stature(ISS). Methods : Glucose and insulin concentrations were measured during oral glucose tolerance test (OGTT) before and after GH treatment(0.6-0.7 IU/kg/week) in 20 patients with ISS. Insulin resistance was assessed by homeostasis model assessment(HOMA). Results : During OGTT, the mean blood glucose level did not show any significant changes after GH treatment. However, mean blood insulin levels of fasting and 30 minutes of OGTT showed significant increases after GH treatment, accompanying significant increases of insulin resistance. There was no difference in change of glucose, insulin levels and insulin resistance before and after GH treatment between two groups of body mass indices(BMI) of 25< and >25. There also was no significant difference between two groups of with and without family histories of diabetes mellitus (DM). There was no case of newly developed impaired glucose tolerance, fasting glucose tolerance, nor newly developed DM. Conclusion : GH treatment with doses of 0.6-0.7 IU/kg/week for mean 9.6 months in patients with ISS did not show any significant changes in blood glucose levels during OGTT. However, GH treatments induced considerably higher fasting insulin levels compared to pretreatment, resulting in statistically higher insulin resistance. Higher BMI and family history of DM did not induce any significant changes in glucose, insulin level and insulin resistance after GH treatment than the other groups.

• Korean Journal of Food Science and Technology
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• v.48 no.2
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• pp.178-186
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• 2016

The present study was conducted to investigate the effect of whole wheat bread with added Lindera obtusiloba (LO) and Capsosiphon fulvescens (CF) ethanol extracts on serum glucose and lipid levels in Sprague Dawley rats. Rats were divided into five groups depending on the diet administered: normal bread (NC), whole wheat bread (W), whole wheat bread with LO leaves extract (WL), whole wheat bread with CF extract (WC), and whole wheat bread with freeze-drying CF (WDC). After 4 weeks of consuming the experimental diet, the blood glucose level and hemoglobin A1c contents were found to be significantly lower in the W, WL, WC, and WDC groups than in the NC group. The high-density lipoprotein-cholesterol levels increased in the WL group when compared to those in the NC group and triglycerides levels decreased in all wheat groups compared to those in the NC group. These results suggest that wheat breads containing LO and CF extracts are effective for preventing hypercholesterolemia and obesity.

• Clinical and Experimental Pediatrics
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• v.50 no.6
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• pp.565-569
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• 2007

Purpose : With a duration of action of approximately 24 hours and peakless levels, Lantus is a more physiologic basal insulin analogue compared with NPH. The aim of this study was to compare the glycemic control of Lantus plus Humalog with that of premixed insulin in children and adolescents with type 1 diabetes mellitus. Methods : The subjects consisted of 25 patients with type 1 diabetes mellitus, aged 12-19 years, who changed their insulin regimen from premixed insulin to Lantus plus Humalog. Daily insulin doses, frequency of hypoglycemia, fasting blood glucose, C-peptide concentration and HbA1c before and 6 months after Lantus treatment were compared. 24 hour blood glucose of 11 patients among Lantus treatment group (n=25) and premixed insulin treatment group (n=10) were self-monitored and compared. Results : 6 months after Lantus treatment, the episodes of hypoglycemia were reduced by 50%(15.1 vs. 7.6 events/month), especially nocturnal hypoglycemia by 67%(6.7 vs. 2.5 events/month). HbA1c was reduced from 9.3% to 8.7% after Lantus treatment. Self-monitored blood glucose of Lantus treatment group at postbreakfast 30, 60, 90 and 120 minutes were 171.1, 169.5, 171.0 and 154.1 mg/dL respectively and lower than those of premixed insulin treatment group (259.7, 282.7, 280.0 and 250.9 mg/dL respectively). Conclusion : Compared with premixed insulin, Lantus plus Humalog is more effective in glycemic control and reduction in nocturnal hypoglycemia in children and adolescents with type 1 diabetes mellitus.

• The Monthly Diabetes
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• s.216
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• pp.10-13
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• 2007

요즈음은 인터넷이나 대중매체를 통해 일반인들도 다양한 질병에 대한 많은 정보를 얻을 수 있다. 이에 속하는 것으로 당뇨병은 대표적 만성질환이며 누구나 한번쯤은 들어 본 적이 있는 질환일 것이다. 현대와 같이 고도로 의학이 발달한 상황에서도 만성질환은 완치되는 것이 아니고 평생 관리를 해야하는 질병이기 때문에 많은 환자들이 살아가는 동안 서서히 지치게 되고 관리를 소홀히 하게 됨으로써 당뇨병성 신경병증, 망막증, 신증, 대혈관병증(뇌졸중, 심혈관질환, 말초혈관질환) 등과 같은 합병증의 발생으로 일상생활에 지장을 받게 된다. 따라서 당뇨병환자는 일생 주기적으로 검사와 함께 자신에게 맞는 약을 복용하고 경우에 따라서는 인슐린 주사까지 맞음으로써 지속적인 혈당관리를 하여 합병증의 발생을 최소화 하는 것이 필요하다. 이상에 언급한 다양한 합병증 중 가장 중요한 사망원인은 심혈관질환으로 40세 이후에 발생한 당뇨병환자에서 전체 사망 원인의 50% 이상을 차지한다. 또한 대부분의 당뇨병성 만성합병증이 적극적인 혈당관리로 효과적인 예방이 가능한 반면 심혈관질환과 같은 대혈관합병증은 혈당조절이 잘 되고 있는 환자에서도 당뇨병 발생 기간과 무관하게 발생하고 또 여러 혈관에 걸쳐 다발적이고 광범위하게 발생하므로 원인이 되는 다른 위험요소들에 대한 관리가 함께 이루어져야 한다.

• Journal of Veterinary Clinics
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• v.31 no.5
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• pp.430-434
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• 2014

Two dogs were referred with the clinical signs of depression and constipation, respectively. One dog with depression had hypoglycemia on biochemistry. On survey abdominal radiographs, a soft tissue density round mass with calcified spots was identified cranial to the urinary bladder. On ultrasonographs, a solitary oval heterogeneous complex-echoic mass with well-defined margin was found. On surgery, the mass was pedunculated and originated from the colonic wall. The resected mass was confirmed as colonic leiomyoma. The other dog with constipation had normal CBC and biochemistry values. On survey abdominal radiographs, there was a soft tissue density round mass dorsal to the descending colon and rectum. The descending colon was displaced ventrally and narrowed by the mass. On ultrasonographs, a well-defined round heteroechoic mass compressed the colon. The mass was also pedunculated and originated from the colonic wall on surgery and confirmed as colonic leiomyoma. Two dogs recovered without any clinical signs after surgery and showed permanent resolution of the clinical signs, respectively.

• Journal of Veterinary Clinics
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• v.32 no.2
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• pp.180-182
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• 2015

A 3 year-old pregnant female Yorkshire terrier dog was presented with major complaints of polyuria and polydipsia. Laboratory tests found persistent hyperglycemia and glucosuria. Abdominal ultrasound study found 2 dead fetuses. Ovarian hysterectomy was performed to remove the dead fetuses. After ovarian hysterectomy, the level of blood glucose was returned to normal range. In addition, the clinical signs and urine glucose were all disappeared. Based on findings on laboratory tests and follow-up study, the case was diagnosed as gestational diabetes mellitus. To our best knowledge, this is the first case report describing a gestational diabetes mellitus of dog in Korea.

• Journal of agricultural medicine and community health
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• v.38 no.2
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• pp.108-115
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• 2013

Objective: This study aimed to examine the effects of chronic disease management program based on clinics for blood pressure control or glycemic control in patients with hypertension or type 2 diabetes mellitus in Incheon. Methods: An observational follow up study was done on 11,501 patients registrated at clinics from January 1st to December 31st, 2010 in Incheon. Experience of education and mandatory laboratory tests were assessed with the registration data and income status was identified by National Health Insurance data. The odds ratio and 95% confidence intervals were derived from logistic regression models. Results: The experience of education has a positive effect for blood pressure control in the non-control group with hypertension at the time of registration (Odds ratio 1.357, confidence intervals: 1.112~1.655). The experience of mandatory laboratory tests has a positive effect for blood pressure control in the control group with hypertension at the time of registration (Odds ratio 1.738, confidence intervals: 1.387~2.178). But the effects of the experience of education and mandatory laboratory test in patients with type 2 diabetes mellitus were not identified. Conclusions: This study revealed the relationship between the experience of education or mandatory laboratory testing and blood pressure control in patients with hypertension.