• Korean Journal of Food Science and Technology
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• v.39 no.3
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• pp.348-352
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• 2007

Inflammation is a complex process resulting from a variety of mechanisms. Combined inhibition of the activities of enzymes involved in the process may therefore be considered more important in anti-inflammatory property of plant extracts than any single contribution. In this study, the inhibitory effects of the ethanol extracts of thirty plant foods on the activities of secretory phospholipase $A_{2}$ ($sPLA_{2}$), cyclooxygenase-1 (COX-1), cyclooxygenase-2 (COX-2), and 12-lipoxygenase (12-LOX) were examined. Several legumes, mungbean sprout and some leaf vegetables inhibited the activity of $sPLA_2$, upstream enzyme of inflammation pathway. Only soybean sprout and mungbean sprout significantly inhibited 12-LOX activity. Although most of extracts inhibited the activities of both COX-1 and COX-2, water dropwort and amaranth showed selectivity for the inhibition of COX-2 over COX-1. Especially, mungbean showed anti-inflammatory property at both upstream and downstream of inflammation pathway with relatively low $IC_{50}$ values for $sPLA_{2}$ and COX-2 enzymes. Mungbean sprout exhibited inhibitory effects on all enzymes related to early and late inflammation and soybean sprout suppressed 12-LOX and COX-2 simultaneously, although the activities of these plants were showed at relatively high concentration. Therefore, mungbean, mungbean sprout, and soybean sprout appear to exhibit anti-inflammatory effects by combined inhibition of inflammatory enzymes.

• Fire Science and Engineering
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• v.34 no.3
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• pp.43-48
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• 2020

The purpose of this study is to develop an earth leakage alarm circuit breaker, equipped with a leakage alarming function (JER-E2S, ETECKOREA Co., Korea), and to analyze its characteristics. The developed mechanism is exclusively used for single-phase and 220 V circuits, with a rated current of 32 A, 20 A, 20 A (for restrooms), 16 A, etc. It satisfies all characteristics of existing earth leakage circuit breakers (ELB). If a fire current, which is a resistive leakage current (Igr), flows through an electric line, the device detects the leakage current in real time and warns against the leakage through a blinking LED lamp. Since the developed device displays a tolerance to a capacitative leakage current (Igc) that inevitably occurs in LED lamps, communication devices, etc., it ensures a stable power supply. In addition, the earth leakage alarm circuit breaker protects against power failure due to a momentary ground fault. Therefore, it can supply power without the risk of the circuit breaker malfunctioning due to a momentary ground fault caused by water droplets, leaves, etc. Moreover, with a standby power of less than 0.1 W, the developed earth leakage alarm circuit breaker exhibits a power saving performance that is 3~8 times greater than that of other ELBs. Installation of approximately 10 earth leakage alarm circuit breakers in one apartment household, with an area of 120 ㎡, can save 2~5 kWh per month. Therefore, the developed earth leakage alarm breaker not only satisfies the characteristics of existing earth leakage breakers, but also exhibits outstanding power supply quality since it has the functions of electric fire prevention and malfunction prevention. Therefore, this device can innovatively contribute to electric fire prevention.

• Korean Journal of Clinical Laboratory Science
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• v.51 no.2
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• pp.221-234
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• 2019

Cancer is genetically, metabolically and infectiously induced life threatening disorder showing aggressive growing pattern with invasive tendency. In order to prevent this global menace from jeopardizing human life, enormous studies on carcinogenesis and treatment for chemotherapy resistance have been intensively researched. Hinokitiol (${\beta}$-thujaplicin) extracted from heart wood of cupressaceous is a well-known bioactive compound demonstrating anti-inflammation, anti-bacteria and anti-cancer effects on several cancer types via apoptosis and autophagy. This study proposed that hinokitiol activates transcription factor EB (TFEB) nuclear translocation for autophagy and lysosomal biogenesis regardless of nutrient condition in cancer cells. Mitophagy and ${\beta}$-catenin translocation into the nucleus under treatment of hinokitiol on non-small cell lung cancer (NSCLC) cells and HeLa cells were investigated. Hinokitiol exerted cytotoxicity on HeLa and HCC827 cells; moreover, artificially induced autophagy by overexpression of TFEB granted imperfect sustainability onto HeLa cells. Taken together, hinokitiol is the prominent autophagy inducer and activator of TFEB nuclear translocation. Alternative cancer therapy via autophagy is pros and cons since the autophagy in cancer cells is related to prevention and survival mechanism depending on nutrition. To avoid paradox of autophagy in cancer therapy, fine-tuned regulation and application of hinokitiol in due course for successful suppressing cancer cells are recommended.

• Proceedings of the Korean Society for Emotion and Sensibility Conference
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• 1999.11a
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• pp.401-406
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• 1999

생활이 풍족해질수록 사람들은 음식이나 음료를 통하여 미각을 즐기는 경향이 강해지고 있다. 미각이 발달한 사람들은 다른 감각이 발달한 사람들보다 소비 욕구가 왕성하여 상품정보에 밝은 편이고 신제품에 대한 호기심도 많아 주요고객으로 환영받을 수 있는 가능성이 매우 높다. 이러한 점을 고려할 때 미각은 소비성향의 척도가 될 수 있으며, 이것이 상품개발에 중요한 지표가 될 가능성이 있다. 그러나 맛에 민감하다거나 둔감하다고 표현되는 개인의 미각물질에 대한 감도는 개인마다 일정치 않다. 이것은 미각물질에 따라 개인의 상대적인 역치의 고조나 미각 강도의 대소가 다르거나 감도가 다른 미각물질에 대한 수용구조에 개인차가 있기 때문이다. 이처럼 개인차가 있는 미각을 표준화된 방법으로 측정하는 것은 그리 쉬운 일이 아니다. 미각강도 측정을 위한 Time-Intensity curve는 1958년 음식물의 특성에 대해 관심을 가졌던 Nielson에 의해 개발되었는데 최근에 Takagi와 Asakura가 Time-Intensity curve분석과 기록을 위해 microcomputer를 이용한 방법을 개발하였다. 그들의 방범은 Time-Intensity curve를 모니터에 보여주고 data를 floppy discs에 기록하여 software로 분석하는 것이다. 본 연구는 이것을 좀더 편리하고 단순하게 만들기 위해 감각의 강도를 전기적 저항의 interface를 통하여 computer에 입력하는 대신에 mouse를 이용하여 입력하는 방법을 개발하였다. 새로이 개발된 Time-Intensity curve를 이용하여 커피성분 중 설탕과 프림의 농도에 변화를 주어 맛의 좋고 싫음의 미각강도를 측정하는 실험을 하였다. 그 결과 상품개발의 중요한 지표가 되는 미각의 강도를 측정할 수 있었고 이것은 향후 commercial한 상품의 개발에 유용한 지표가 될 것이라고 본다.시사한다. 본 연구에서는 한국 연구 조직에서 일하는 외국인 연구자들의 동기 및 성과에 영향을 미치는 많은 요인들을 확인할 수 있었다. 상관관계, 분산분석, 회귀분석 등을 통해 활용 성과에 미치는 영향 요인들을 도출하였다. 설문 분석을 통하여 동기 및 성과 사이에는 강한 상관관계가 존재하는 것을 확인할 수 있었으며 이는 전통적인 동기 이론들과 부합한다. 대부분의 변수가 동기 및 성과에 동시에 영향을 미치는 것으로 조사되었으며 그중에서도 조직 협력 문화, 외국인 연구자의 의사소통 및 협력성, 외국인 연구자의 연구 능력 관련 변수들 및 연구 프로젝트의 기술수명주기, 외국인 연구자의 기존 기술지식의 흡수 등이 가장 중요한 변수로 나타났다. 이는 우리가 주로 중국 및 러시아 과학자들을 활용하여 상업화하는 외국인 연구인력 활용 패턴과도 일치하는 결과이다. 즉 우호적인 조직문화를 가지고 있는 연구 조직에서, 이미 과학기술 지식을 많이 가지고 있고 연구 능력도 높은 외국인 과학기술자를, 한국에서 기술이 태동 또는 성장하고 있는 연구 분야에서 활용하는 것이 가장 성과가 좋다는 사실을 확인시켜 주고 있다. 국내에서 최초로 수행된 본 연구는 외국인 연구 인력의 활용 성과가 매우 높으며, 우리의 과학기술혁신시스템을 보완하는 유효한 수단으로써 외국인 연구 인력이 중요한 대안이 될 수 있음을 발견하였다. 외국인 연구 인력을 잘 활용하기 위하여 문제점 및 개선방안을 활용 환경, 연구 인력이 중요한 대안이 될 수 있음을 발견하였다. 외국인 연구 인력을 잘 활용하기 위하여 문제점 및 개선 방안을 활용 환경, 연구 인력관리. 인력 교류사업, 외국인 과학자 지원 창구 등으로 나누어서 정리하였다. 연구시설, 주거시설 등의 하드웨어적 환경에 대한 개선도 중요하지만 연구 인력의 관리 능력 제고, 인력 교류 사업의 개선, 정보 제공 등 소프트웨어적인 활용 능력을 제고하는데 정책적인 관심을 기

• Journal of the Institute of Electronics Engineers of Korea SD
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• v.38 no.10
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• pp.712-720
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• 2001

Algorithms from the research of the layout migration were proposed in the paper. These are automatic recognition algorithm for the VLSI devices from it, graph based construction algorithm to maintain the constraints, dependencies, and design rule between the devices, and high speed compaction algorithm to reduce size of the VLSI area and reuse the design with compacted size for the new technology. Also, this paper describes that why proposed algorithms are essential for the era of the SoC (System on a Chip), design reuse, and IP DB, which are the big concerns in these days. In addition to introduce our algorithms, the benchmark showed that our performance is superior by 27 times faster than that of the commercial one, and has better efficiency by 3 times in disk usage.

• Journal of vocational education research
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• v.30 no.4
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• pp.1-22
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• 2011

Paradoxically, leadership has not only positive effects but also negative effects. The purpose of this study is to examine supervisors' dysfunctional leadership behaviors, antecedents and results in order to draw HRD implications for protecting organizations and employees from dysfunctional leaders and provide implications for leadership development. A qualitative research method based on semi-organized interviews with 28 employees from S-group was used. The results of this study show that the dysfunctional leadership behaviors were associated with ten behavioral categories: belittling and insulting the subordinates, authoritative and arbitrary behaviors, self-aggrandizement, biased preference for certain personnel, arrogance, micro-managing, inability to change and adapt, discordance between words and actions, over-dependance on supervisor, lack of ethics and values. Dysfunctional leadership behaviors were casually attributed to 'personal traits & experience', 'task characteristics', and 'internal & external environments of the organization'. Finally, the results of supervisor's dysfunctional leadership behaviors on employees and the organizational effects were 'increased turnover rate', 'declining work efficiency', 'collapsing morale', 'retraining innovative thinking', 'passive working culture', 'discouraging organizational vitality', 'discouraging organizational synergy', 'losing loyalty' and 'declining trust on supervisor'.

• Management & Information Systems Review
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• v.36 no.3
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• pp.167-184
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• 2017

In this study, we investigated the effect of offline banking trust on smart banking trust. As influencing factors of smart banking trust, this study compared offline banking trust, smart banking's system quality, and information quality. For the empirical study, 186 questionnaire data were collected from smart banking users and the data were analyzed using Smart-PLS 2.0. As results, it was verified that there is trust transfer in FinTech service, by the significant effect of offline banking trust on smart banking trust. And it was proved that the effect of offline banking trust on smart banking trust is lower than that of smart banking itself. The contribution of this study can be seen in both academic and industrial aspects. First, it is the contribution of the academic aspect. Previous studies on banking were focused on either offline banking or smart banking. But this study, focus on the relationship between offline banking and online banking, proved that offline banking trust affects smart banking trust. Next, it is the industrial contribution. This study showed that offline banking characteristics of traditional commercial banks affect the trust of emerging smart banking service. This means that the emerging FinTech companies are not advantageous in the competition of trust building compared to traditional commercial banks. Unlike traditional commercial banks, the emerging FinTech is innovating the convenience of customers by arming them with new technologies such as mobile Internet, social network, cloud technology, and big data. However, these FinTech strengths alone can not guarantee sufficient trust needed for financial transactions, because banking customers do not change a habit or an inertia that they already have during using traditional banks. Therefore, emerging FinTech companies should strive to create destructive value that reflects the connection with various Internet services and the strength of online interaction such as social services, which have an advantage over customer contacts. And emerging FinTech companies should strive to build service trust, focused on young people with low resistance to new services.

• Proceedings of the Korean Institute of Information and Commucation Sciences Conference
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• 2017.05a
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• pp.463-466
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• 2017

The purpose of this paper is to develop a module capable of all-directional driving different from conventional wheeled robots, and to solve the problems of the conventional mobile robot with side driving performance degradation, It is possible to overcome the disadvantages such as an increase in the time required for the unnecessary driving. The all - direction spherical wheel drive module for driving a ball - balancing robot is required to develop a power transfer mechanism and a driving algorithm for driving the robot in all directions using three rotor casters. 3DoF (Axis) A driver with built-in forward motion algorithm is embedded in the module and a driving motor module with 3DoF (axis) for driving direction and speed is installed. The movement mechanism depends on the sum of the rotation vectors of the respective driving wheels. It is possible to create various movement directions depending on the rotation and the vector sum of two or three drive wheels. It is possible to move in different directions according to the rotation vector field of each driving wheel. When a more innovative all-round spherical wheel drive module for forward movement is developed, it can be used in the driving part of the mobile robot to improve the performance of the robot more technically, and through the forward-direction robot platform with the drive module Conventional wheeled robots can overcome the disadvantage that the continuous straightening performance is lowered due to resistance to various environments. Therefore, it is necessary to use a full-direction driving function as well as a cleaning robot and a mobile robot applicable in the Americas and Europe It will be an essential technology for guide robots, boarding robots, mobile means, etc., and will contribute to the expansion of the intelligent service robot market and future automobile market.