• Ocean and Polar Research
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• v.38 no.4
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• pp.287-294
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• 2016

Marine sponges have been a remarkably rich source of pharmacologically active and structurally diverse natural products. As a part of our continuing search for novel secondary metabolites of biomedical importance from marine invertebrate, we encountered the sponge Lipastrotethya sp. from Chuuk, Micronesia. The crude organic extract of this animal exhibited considerable cytotoxicity against the K562 cell line. Guided by the $^1H$ NMR analysis, flash chromatography of the crude extract followed by HPLC yielded a new triterpene glycoside, along with ten known saponins of the sarasinoside class. The structure of this new compound was determined by combined spectroscopic methods such as COSY, HSQC and HMBC experiment. Among these metabolites, six compounds exhibited moderate cytotoxicity against ACHN, MDA-MB-231, NCI-H23 and NUGC-3 cell lines.

• 사료
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• s.69
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• pp.14-17
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• 2014

${\Box}$ 제82차 세계동물보건기구(OIE) 총회가 지난 5월 24일~5월 30일까지 프랑스에서 158개국 500여명이 참석한 가운데 개최 ${\bigcirc}$ 총회에는 WHO, FAO 등 국제기구와 함께 브라질, 독일 등 41개국 장관 및 차관 등 고위급 인사 참석 ${\Box}$ 우리나라는 농림축산식품부(이하 농식품부) 차관보를 단장으로 대표단을 구성하여 현지 대응 등을 통해 OIE 총회에서 구제역(FMD), 소해면상뇌증(BSE, 일명 광우병) 등 4개 질병 청정국 지위를 획득함 ${\bigcirc}$ 4개 질병 청정국은 구제역(백신접종 청정국), 소해면상뇌증(위험무시국), 가성 우역 아프리카마역(청정국) ${\Box}$ 구제역, BSE 등 청정국 지위획득은 우리나라 축산물의 안전성에 대한 신뢰성 제고, 수출가능성 확대 등 효과가 기대됨 ${\Box}$ 농식품부는 청정국 획득만큼이나 앞으로 청정국 유지가 중요하다고 강조하면서, 축산농가 및 국민들의 지속적인 방역 협조를 당부함.

• The Korean Journal of Zoology
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• v.35 no.4
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• pp.414-427
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• 1992

Octopus variabilis의 흡반을 광학현미경과 주사전자현미경 그리고 투과전자현미경을 이용하여 그 미세구조를 관찰하였기에 이에 보고하는 바이다. 또한 내측상피 부위 돌기구 조물 속에서 관찰된 세포들은 핵을 둘러싼 세포들이 공포화 현상으로 인하여 해면처럼 보였다. 이 세포들은 감각과 수축에 관여하는 해면질성인 세포로 생각된다. 외측 상피조직에서는 2종의 분비성인 감각세포(A 및 B형세포)차 2종의 상피성인 감각세포(C 및 D형세포)가 관찰되었다. 분비성인 감각세포는 감각이외에 점액분비 기능을 소지하였으며, 상피성인 감각세포는 상피의 지지와 감각기능을 수행하는 것으로 생각되었다. 흠반을 구성하고 있는 근섬유는 중앙이 기린 도나스 형태로서 10-15개의 종선이 나타났다. 또한 부위에 따라서는 근섬유들은 서로 집결하여 원주형의 근육 기등을 형성하기도 했는데 이들은 신경섬유에 의하여 서로 연결 되고 통제되었다.

• Animal Systematics, Evolution and Diversity
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• v.20 no.1
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• pp.21-29
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• 2004

As a result of continuous taxonomic study on shrimps collected from Korean waters, two alpheid shrimps, Alpheus paralcyone and A. spongiarum, are newly reported from Korean waters. These species belong to the crinitus group of the genus Alpheus. Korean Alpheidae fauna now consists of 18 species of six genera.

• Animal Systematics, Evolution and Diversity
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• v.8 no.2
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• pp.301-324
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• 1992

A large number of Demospongiate have been collected from 18 localities in Cheju Island and its adjacent waters during the period from 1970 to 1991. The identified Demospongiae consist of 67 species, 40 genera and 30 families. Among them 11 species were new to Koera; Oxeostilon fernaldi, Microciona gradalis, Tedania ignis, Haliclona koremella, Adocia neens, Callyspongia variabilis, Suberites axinelloides, Anthosigmella raromicrosclera, Epipolasis kushimotoensis, Acanthella insignia, and Spongosorites salimonensis.

• The Korean Journal of Malacology
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• v.32 no.4
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• pp.297-328
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• 2016

This study was performed to know and compare the community structures of macrobenthic invertebrates of five fishing grounds in the coastal waters of Jeju Island from 2013 to 2015. A total of 629 species was identified. Molluscans comprised 282 species (44.8%), Arthropods 88 (14.0%), Poriferans 61 (9.7%), Bryozoans 52 (8.3%) and the others including Cnidarians 51 (8.1%). Density and biomass were estimated to be $71,007ind./m^2$ and $599,208.0gwwt/m^2$, respectively. Gastropods was the most dominant taxon in terms of abundance ($24,625ind./m^2$ ) and number of species as well, and Gastropods was predominant in biomass ($190,789.0gwwt/m^2$). The dominant species were Omphalius pfeifferi, Astralium haematragum, Musculus viridulus, Halosydna brevisetosa, Phascolosoma scolops, Herdmania monus in 5-20 m. Based on the cluster analysis, the study area could be divided into five station groups. The biodiversity, evenness and richness index appeared as follows: H' = 4.28-4.64, E' = 0.74-0.79, R = 33.17-35.45. The dominance index were highest in Sagye and lowest in Sinhung.

• Korean Journal of Clinical Laboratory Science
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• v.54 no.4
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• pp.307-315
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• 2022

Since attaining middle age, many patients suffer from the post-micturition dribble (PMD) syndrome but do not receive proper treatment. This is because the etiology and treatment mechanisms of PMD differ from conventional lower urinary tract symptoms. Several pathophysiologies have been proposed, but the mechanisms we observed are the weakening of the bulbocavernosus muscle and dilation of the urethra due to atrophy of the cavernosal tissue. This study investigates the mechanism of PMD by observing anatomical changes in the corpus cavernosum and urethra. SD male rats were categorized by age into the young rats group (8 weeks old) and the old rats group (24 months or more). The ratio area of the bulbous urethra and corpus cavernosum to the total penis was statistically significant between both groups (P<0.05). Significant differences were obtained between the two groups for restored smooth muscle contents and several other parameters related to PMD mechanisms (nNOS, α-SMA) (P<0.05). The changes in size and parameters of the urethra and corpus cavernosum in young and old rats were confirmed. The results from this study are expected to contribute to the study of PMD in the future.

• The Korean Journal of Malacology
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• v.27 no.3
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• pp.229-246
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• 2011

This study was performed to know and compare the community structures of macrobenthic invertebrates of eight fishing grounds in the coastal waters of Jeju Island from September to October 2008. A total of 166 species was identified. Mollusks comprised 77 species (46.4%); Arthropods 24 (14.5%), Cnidarians 18 (10.8%); Poriferans 16 (9.6%); and the others including Echinoderms 33 (17.7%). Density and biomass were estimated to be 6,905 ind./$m^2$ and 113,100.7 gwwt/$m^2$, respectively. Gastropods was the most dominant taxon in terms of abundance (3,311 ind./$m^2$) and number of species as well, and Gastropods was predominant in biomass (55,789.2 gwwt/$m^2$). The dominant species were Omphalius pfeifferi, Astralium haematragum, Turbo cornutus, Ergalatax contraacta, Lithophaga cura, Anthocidaris crassispina, Herdmania monus in 5-15 m. Based on the cluster analysis, the study area could be divided into two station groups. The biodiversity, evenness and richness index appeared as follows: H' = 1.59-2.95, E' = 0.38-0.87, R = 3.3-10.4. The dominance index were highest in Daepo and lowest in Woljeong.

• Journal of Food Hygiene and Safety
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• v.32 no.1
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• pp.70-74
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• 2017

Recently, the area of marine resources has become concerned with sources for the next generation of the bio-industry. Until present, development of the marine resources has remained limited, although a large number of these resources are considered to have potential for various significant biological activities. Most marine sponges, marine algae and coral could be used to create specific compounds for survival against a harsh environment. Therefore, it was necessary that these materials needed to be elucidated with biological activities, such as like anti-inflammatory, anti-viral or anti-cancer effects for their utilization in the bio-industry. In this study, we screened extracts of marine resources for their anti-cancer effect on human colorectal cancer cells. These resources were collected at Kosrae of Micronesia on April, 2013 and extracted with methanol. Cytotoxicity of marine resources was observed. Of a total of 20 specimens, three specimens dose-dependently demonstration inhibition of cell viability. Furthermore, cells treated with these specimens for 48h were induced p53, p21, Bax and caspase-3. The results suggest that they involved p53-mediated apoptosis. Two positive specimens (1304KO-327 and 1304KO-329) were verified as the identical materials, which are Hyrtios sp. Unfortunately 1304KO-207 was not yet classified and needed to identify in the further study. There results suggested that marine resources with positive potential in anticancer effect would be good candidates as useful bio-resources.

• Animal Systematics, Evolution and Diversity
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• v.1 no.1_2
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• pp.21-30
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• 1985

본인은 1984년 6월부터1985년 5월까지 서해연안(작약도, 대천, 안면도, 안흥)과 남해연안의 삼천포를 중심으로 한 부근섬(신수도, 늑도, 비진도, 충무) 및 거제도, 제주도 등지에서 채집된 재료 90여점과 그간 미해결로 보류되어있던 기존 표본들을 동정분류한 결과 26 종의 기록종과 3 종의 한국 미기록종(Spongia officienalis , S. zimmocca, Tedania Tublifera)이 밝혀졌다. 기록종 가운데 Esperiopsis uncigera 와 Hymeniacidon sinapium은 재검토되었다.