• Title/Summary/Keyword: 항암효과

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ABTS Radical Scavenging and Anti-Tumor Effects of Tricholoma matsutake Sing. (Pine Mushroom) (송이(Tricholoma matsutake Sing.)의 ABTS Radical 소거능과 암세포 생장 억제효능의 검색)

  • Kim, Young-Eon;Yang, Ji-Won;Lee, Chang-Ho;Kwon, Eun-Kyung
    • Journal of the Korean Society of Food Science and Nutrition
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    • v.38 no.5
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    • pp.555-560
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    • 2009

  • Pine mushroom (Tricholoma matsutake Sing.) is an expensive and highly prized delicacy in Korean and Japanese cuisines with its unique flavor and functional properties. The pine mushroom juice (PMJ) was investigated for its antioxidant and anti-tumor activities with ABTS radical scavenging method and MTT assay. The phenolic contents in pine mushroom juice ranged from 1.19 to 54.99 GAEs mg/100 mL at the concentrations of $1{\sim}50\;mg/mL$. The ABTS radical scavenging activities of pine mushroom juice were 7.0%, 81.7% and 91.8% at the concentrations of 1, 10 and 50 mg/mL, respectively. The $IC_{50}$ values of pine mushroom juice were 605.9, 788.4, 583.6 and $232.5{\mu}g/mL$ on the cytotoxicities against AGS, HeLa, HepG2 and HT-29, respectively, and PMJ showed the strongest growth inhibitory activity against HT-29 cell. These results suggested therapeutic potential for pine mushroom juice as an anti-oxidant and anti-tumor agent.

  • https://doi.org/10.3746/jkfn.2009.38.5.555 인용 PDF KSCI