• Journal of Society of Preventive Korean Medicine
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• v.8 no.1
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• pp.163-186
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• 2004

The purpose of this parer is to identify the input-output structure of oriental medicine and its alternative medicine industries in an inter-industry context and to estimate its forward and backward effects on macroeconomic variables such as production, employment and price level. Input-output tables released by The Bank of Korea were used as data in this research and inter-industry analysis was adopted as research methodology. The industry takes less share of production, price and trade in a Korean economy, compared with other industry. However, the industry's capability of creating value added is estimated to be well above that of other industry and that of making new employments is as more than 4 times as other industries. This result gives us policy implications that the government should enhance its subsidy policy and economic (tax) incentives for oriental medicine and its related alternative medicine industries.

• Journal of Korean Society of Occupational and Environmental Hygiene
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• v.29 no.1
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• pp.98-107
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• 2019

Objective: This study was carried out to examine factors influencing job stress and health promotion behavior of medical doctors, who play the important role for improving people's health. The data were collected from 340 medical doctors working in clinic and hospitals in Daegu using self-administered questionnaires over the period from July 1 to August 15, 2018. Methods: A multiple regression model was used to study the factors influencing job stress and health promotion behavior of medical doctors. Results: This study showed that average job stress level of the subjects was 3.06 out of 5 point. The medical doctors with carrying out surgery and longer working time tend to have higher job stress level compared to other groups without surgery and having short working time. And medical doctors generally do not have good health promotion behavior and average level of practice of health promotion behavior of the subjects was 2.30 out of 5. The groups with high rate of quitting job and working in hospital tend to have lower practice level of health promotion behavior compared to other groups. And it also showed that the groups with higher the job satisfaction rate and vocational aptitude tended to have the higher level of practice of health promotion behavior compared with other groups. Conclusions: Medical doctors tend to have higher job stress level, whereas they have relatively lower health promotion behavior compared with people with other jobs. Thus, strengthening of health education and counselling for medical doctors and improvement of work environment considering job's characteristics is needed. In particular, the education for job stress management and health promotion in regular continuing education program organized by medical doctors's association should be strengthened.

• Journal of Korean Society for Quality Management
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• v.49 no.4
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• pp.595-607
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• 2021

Purpose: This study introduces a systematic framework to evaluate service satisfaction of cosmetic brands through online review analysis utilizing Text-Mining technique. Methods: The framework assumes that the service satisfaction is evaluated by positive comments from online reviews. That is, the service satisfaction of a cosmetic brand is evaluated higher as more positive opinions are commented in the online reviews. This study focuses on two approaches. First, it collects online review comments from the top 50 global cosmetic brands and evaluates customer service satisfaction for each cosmetic brands by applying Sentimental Analysis and Latent Dirichlet Allocation. Second, it analyzes the determinants that induce or influence service satisfaction and suggests the guidelines for cosmetic brands with low satisfaction to improve their service satisfaction. Results: For the satisfaction evaluation, online review data were extracted from the top 50 global cosmetic brands in the world based on 2018 sales announced by Brand Finance in the UK. As a result of the satisfaction analysis, it was found that overall there were more positive opinions than negative opinions and the averages for polarity, subjectivity, positive ratio, and negative ratio were calculated as 0.50, 0.76, 0.57, and 0.19, respectively. Polarity, subjectivity and positive ratio showed the opposite pattern to negative ratio, and although there was a slight difference in fluctuation range and ranking between them, the patterns are almost same. Conclusion: The usefulness of the proposed framework was verified through case study. Although some studies have suggested a method to analyze online reviews, they didn't deal with the satisfaction evaluation among competitors and cause analysis. This study is different from previous studies in that it evaluates service satisfaction from a relative point of view among cosmetic brands and analyze determinants.

• Proceedings of the Korean Institute of Information and Commucation Sciences Conference
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• 2021.10a
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• pp.159-160
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• 2021

We are facing major changes such as an aging population along with the 4th industrial revolution based on ICT technologies such as artificial intelligence, the Internet of Things, autonomous driving, and factory automation. For the local governments that are indexed in high population extinction risk, it is essential to consider market expansion and re-education policies suitable for regional characteristics in order to respond to changes such as advanced industrial automation and population aging. For the reemployment of the elderly, we will analyze previous public strategies for elderly-friendly jobs, expand investment in age-friendly industries. In this study, we suggest to improvement direction of the elderly labor market in Cheonan-Si.

• The Journal of Korean Medicine
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• v.19 no.1
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• pp.430-443
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• 1998

The research on the actual condition of the oriental health related industry has been made with defining it's phase. As a result, I have come to develope korean-type health model, which can solve the problems derived from the past herb medicine industry. The prospects and roles of the oriental health related industries are as follows: The phase adjustment of the oriental health related industry. The problems of modern medical science happens in the beginning of 21st century, the importance of oriental health improvement in the field of health business is now being on the rise. therefore it is necessary to readjust the present status of the oriental medicine and to take it into health area. Should the responsible institutes regarded on oriental medicine make clear prescription in terms of oriental health industry's role and limitation, they could contribute health circumstance in the 21st century. This is because oriental health related industry can be utiliged in not only protective area and curable area. The present situation of the oriental health related industry. These herb medical societies are flooded with various oriental health industry apart from the legal systematic control so far health industry apart from the legal systematic control so far. The expected survey can not be complete but random under these situations. Nevertheless oriental medical health industry area such as a diet cure, exercise treatment and living condition cure are being considerably expanded, especially living facilities improvement and mind control areas are toward worldwide. Consquently herb health industries are now？ consistantly developed by the influence of western nature treatment stemmed from the oriental medicine theory. The role and prospect of the oriental health related industry in 21st century. The oriental health industries can be helpful for the human being's health improvement in general but by the lack of scholastic oriental health theory, it does not contribute to the health welfare. If these problems are made up for in the field of theory area, the oriental health related industry will surely have the potentiallity and know how for health welfare. The successive role of these industry is depended on the fact that the characteristics of the oriental medicine should adjust to the real society with the systematic management. In the 21C, oriental health industry will certainly be vitalized owing to the social and periodical request especially in the area of oriental medical industry, oriental health drink industry, oriental health mind exercise industry, oriental health leasure industry and oriental health complex management industry. Among these areas, it is the oriental health complex amagement industry that will be the limestone of prosperity of the oriental health industry in 21C. Proposal for the social contribution of the oriental health related industry in the 21C. To achive the ultimate role of the oriental health industry in the 21c, first we should know how to use the oriental medicine. Second We should make an effort to revitalize the oriental health industry. So it is indespensible that government, academic institution and enterprise should concentrate their interest on the oriental health industry with common knowledge and systematic management in advance.

• The Korea Journal of Herbology
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• v.39 no.1
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• pp.23-29
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• 2024

Objectives : Polyporus umbellatus is a medicinal mushroom that has been used for over thousands years in Chinese medicine as a powerful diuretic to relieve fluid retention and edema. Dermal papilla is located at the bottom of the hair follicle and connected to the blood vessels where it gets the nutrients and oxygen to nurture hair follicle. This study examined the mechanism through which the ethanol extract of Polyporus umbellatus (EPU) promoted the proliferation of human dermal papilla cells (HHDPCs). Methods : To estimate the proliferative effects of EPU on HHDPCs, cell viability was estimated by thiazolyl blue tetrazolium bromide (MTT) assay. Western blotting was used to investgate the activation of ERK, phosphoinositide 3-kinase (PI3K)/Akt, β-catenin, GSK-3β and heme oxygenase-1 (HO-1). Cells were treated with inhibitors of ERK and Akt prior to EPU treatment. Results : EPU promoted the proliferation of HHDPCs and the phosphorylation of ERK and Akt in dose dependent manner. However, the proliferative effect of EPU on HHDPCs was inhibited by pre-treatment of ERK inhibitor (PD98059) and Akt inhibitor (LY294002). Furthermore, EPU respectively stimulated the protein expression of β-catenin and phosphorylated GSK-3β. EPU significantly increased the protein expression levels of proliferation and cytoprotection related genes such as Bcl-2, SIRT-1, and HO-1 in cells. Conclusion : This results suggest that EPU promoted the proliferation of HHDPCs via activating PI3K/Akt and Wnt/β-catenin signaling pathway in HHDPCs.

• Journal of Physiology & Pathology in Korean Medicine
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• v.36 no.1
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• pp.23-27
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• 2022

This study aims to evaluate the anti-inflammatory effect of 80% ethanol extracts of Stachys affinis (MQ) on 1-fluoro-2,4-Dinitrofluorobenzene (DNFB) induced atopic dermatitis (AD) in Balb/c mice. AD-like allergic contact dermatitis was induced by challenge of DNFB on the ear after DNFB sensitization on the back sides of mice. MQ alleivated clinical severity in AD-like skin lesions. In addition, ear thickness of epidermis and penetration of inflammatory cells in AD-like skin lesions were decreased by topical application of MQ. The the serum levels of tumor necrosis factor-α (TNF-α) and interleukin-4 (IL-4) were measured in AD mice using ELISA kits. Levels of TNF-α and IL-4 in serum were significantly decreased by topical application of MQ. Therefore, this study could give a clinical basis that MQ could be a agent to prevent AD.

• Journal of Sensor Science and Technology
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• v.28 no.3
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• pp.171-176
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• 2019

The biomarkers related to the colorectal cancers and diseases were surveyed and summarized, and an optical electronic nose was researched and developed for their analysis. The prototyped sensor revealed that it could discriminate two gases: ethanol 2000 ppm and $CO_2$ 500 ppm. Furthermore, the sensor demonstrated the potential capability of estimation of $CO_2$ concentration with 95% confidence level. Based on the above experimental results, the developed optical electronic nose was tested with the mixtures of gases (Isopropyl Alcohol, Acetone, Methanol, and Toluene) and the biomarkers were successfully segregated using principal component analysis.

• The Korea Journal of Herbology
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• v.36 no.5
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• pp.125-133
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• 2021

Objectives : Thymus quinquecistatus var. japonica (H.Hara) is a member of the genus Thymus of perennial aromatic herb, and it's designated as a natural monument of South Korea. It has traditionally been known to have protective or therapeutic effects on various human disease including cerebrovascular and neurological disease. Recently it was suggested that essential oil extracted from thyme has anti-fungal and anti-bacterial effect. The aim of this study is to investigate anti-inflammatory effect of Thymus quinquecistatus var. japonica in Raw 264.7 macrophage cell line. Methods : The cytotoxic effects of water and 70% ethanol extracts from Thymus quinquecistatus var. japonica, was tested using MTT assay. Inhibitory effects of the extracts to nitric oxide production and mRNA expression of inflammatory cytokines were examined by RT-PCR. Also, MitoSOX-red assay and JC-1 assay were performed to determine if the extracts can inhibit mitochondrial ROS accumulation and maintain mitochondrial membrane potential. Results : In LPS-induced inflammatory response, the extracts efficiently reduced nitric oxide NO production through inhibiting mRNA expression of iNOS enzyme. In addition, expression of the proinflammatory cytokines, IL-1𝛽 and IL-6, was also down-regulated by the extract treatments. Excessive accumulation of mitochondrial ROS induced by LPS was inhibited in the extract treated cells, which finally protected mitochondrial membrane potential. Conclusions : These results showed that water and 70% ethanol extracts from Thymus quinquecistatus var. japonica have anti-inflammatory effect through down regulation of IL-1𝛽, IL-6, and iNOS, and also have antioxidative effect against mitochondrial ROS accumulation that promote inflammatory response.

• Journal of the Korean Applied Science and Technology
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• v.40 no.6
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• pp.1547-1556
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• 2023

This study was conducted to check the anti-bacterial ability against Malassezia furfur by mixing Szygium aromaticum and Coptis japonica extracts and to evaluate the antioxidant and anti-inflammatory ability by creating an optimal mixture. Szygium aromaticum and Coptis japonica were extracted with 70% ethanol, 100% methanol, and water to evaluate the antibacterial ability, and it was confirmed that 100% methanol extract of Szygium aromaticum and Coptis japonica water extract had the highest anti-bacterial ability. In addition, when the two extracts were mixed and the anti-bacterial ability was evaluated by ratio, the ratio of 9:1 showed the best activity, and it was confirmed that the antioxidant activity of the mixture was excellent. In Raw 264.7 cells, LPS was used to induce inflammatory responses and confirmed anti-inflammatory activity at 1, 10, 50, and 100 ㎍/mL that did not affect survival, and it was confirmed that NO-production inhibition and IL-6 expression inhibition and COX2 and iNOS protein expression inhibition activity were excellent at 10, 50, and 100 ㎍/mL. Through this study, it is thought that the mixture of Szygium aromaticum100% methanol extract and Coptis japonica water extract can be used as a natural ingredient in functional cosmetics because of its excellent antibacterial and anti-inflammatory effects.