• Title/Summary/Keyword: 한국HP

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Backbone 1H, 15N, and 13C Resonance Assignments and Secondary-Structure of the Conserved Hypothetical Protein HP0892 of Helicobacter pylori

  • Han, Kyung-Doo;Park, Sung-Jean;Jang, Sun-Bok;Lee, Bong-Jin
    • Molecules and Cells
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    • v.25 no.1
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    • pp.138-141
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    • 2008
  • HP0892 (SwissProt/TrEMBL ID O25552) is a 90-residue conserved hypothetical protein from Helicobacter pylori strain 26695, with a calculated pI of 9.38 and a molecular mass of 10.41 kDa. It belongs to the Plasmid stabilization system protein family (PF05016) in the Pfam database. Proteins with sequence similarity to HP0892 exist in Vibrio choierae, Enterococcus faecalis, Campylobacter jejuni, Streptococcus pneumoniae, Haemophilus influenzae, Escherichia coli O157. Here we report the sequence-specific backbone resonance assignments of HP0892 using multidimentional heteronuclear NMR spectroscopy. About 97.0% (422/435) of the HN, N, CO, $C{\beta}$, $C{\alpha}$ resonances of 90 residues of HP0892 were assigned. On the basis of the resonance assignments, three helical regions and four strand regions were identified using the CSI program. This study is a prerequisite for calculating the solution structure of HP0892, and will be useful for studying its interaction with other molecules.

IL-10 Expression-Inducing Gut Bacteria Alleviate High-Fat Diet-Induced Obesity and Hyperlipidemia in Mice

  • Kim, Hye-In;Yun, Soo-Won;Han, Myung Joo;Jang, Se-Eun;Kim, Dong-Hyun
    • Journal of Microbiology and Biotechnology
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    • v.30 no.4
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    • pp.599-603
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    • 2020
  • In the present study, we examined the effects of interleukin (IL)-10 expression-inducing bacteria Bifidobacterium adolescentis HP1, Lactobacillus mucosae HP2, and Weissella cibaria HP3 on high-fat diet (HFD)-induced obesity and liver steatosis in mice. Oral gavage of HP1, HP2, and HP3 reduced HFD-induced bodyweight gain, triglycerides, and total cholesterol levels in the blood and liver. They also suppressed HFD-induced colitis and the fecal δ,γ-Proteobacteria population. Of the tested bacteria, HP2, which most potently inhibited IL-10 expression, also suppressed HFD-induced bodyweight gain, liver steatosis, and colitis most effectively. These findings suggest that IL-10 expression-inducing gut bacteria can suppress obesity and liver steatosis.

Performance Analysis of HP Steam Turbines. of LNG Carriers (LNG 운반선용 증기터빈 고압단의 성능해석)

  • Park, Jong-Hwoo;Chung, Kyung-Nam;Kim, Yang-Ik;Cho, Seoung-Hee
    • 유체기계공업학회:학술대회논문집
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    • 2006.08a
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    • pp.275-278
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    • 2006
  • A steam turbine is one of propulsion systems of a LNG carrier, which consists of high pressure (HP) and low pressure (LP) turbines. In order to obtain high power, each one has the form of a multi-stage turbine. Especially, the first stage of a HP turbine is Curtis stage and uses partial admission considering the turbine efficiency. The performance of a HP turbine can be predicted by a mean-line analysis method, because the relatively large value of hub-tip ratio makes the three-dimensional losses small. In this study, a performance analysis method is developed for a multi-stage HP turbine using Chen's loss model developed for the transonic steam turbines. To consider the feature of partial admission, different partial admission models are reviewed, This analysis method can be used in partial load conditions as well as full load condition. The calculation results are also compared with the CFD results about some simple cases to check the accuracy of the program. Performance of two HP turbine models are calculated, and the calculation results are compared with the designed data. The comparison shows the qualitative performance analysis result.

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Backbone 1H, 15N, and 13C Resonance Assignments and Secondary-Structure of Conserved Hypothetical Protein HP0894 from Helicobacter pylori

  • Han, Kyung-Doo;Park, Sung-Jean;Lee, Bong-Jin
    • Molecules and Cells
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    • v.20 no.3
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    • pp.442-445
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    • 2005
  • HP0894 (SwissProt/TrEMBL ID O25554) is an 88-residue conserved hypothetical protein from Helicobacter pylori strain 26695 with a calculated pI of 8.5 and a molecular weight of 10.38 kDa. Proteins with sequence similarity to HP0894 exist in Vibrio choierae, Enterococcus faecalis, Campylobacter jejuni, Streptococcus pneumoniae, Haemophilus influenzae, Escherichia coli O157, etc. Here we report the sequence-specific backbone resonance assignments of HP0894. About 97.5% (418/429) of the HN, N, CO, $C{\alpha}$, $C{\beta}$ resonances of the 88 residues of HP0894 were assigned. On the basis of these assignments, three helical regions and four strand regions were identified using the CSI program. This study is a prerequisite for calculating the solution structure of HP0894, and studying its interaction with its substrates, if any, and/or with other proteins.

비즈니스 인사이드 - 신진전산폼(주), HP T200 도입 오픈하우스 개최

  • Jo, Gap-Jun
    • 프린팅코리아
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    • v.11 no.9
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    • pp.122-123
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    • 2012
  • 신진전산폼(주)(대표이사 이성국)는 지난 7월 26일 국내 최초로 도입한 HP T200 컬러 잉크젯 웹 프레스 오픈하우스를 개최하고, DM 출판 시장에 컬러 디지털 인쇄를 통한 새 바람을 일으킬 것이라고 선언했다. 이와 함께 한국HP도 첫 잉크젯 웹 프레스 공급으로 개인화 상업용 DM 및 출판 시장의 패러다임을 컬러 디지털 인쇄로 전환할 계획이라고 밝혔다.

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Effects of High Pressure Treatment on Antioxidant Compounds and Activity of Germinated Rough Rice (Oryza sativa L.) (고압처리가 발아벼의 항산화 성분과 활성에 미치는 영향)

  • Kim, Min Young;Lee, Sang Hoon;Jang, Gwi Young;Park, Hye Jin;Meishan, Li;Kim, Shinje;Lee, Youn Ri;Lee, Junsoo;Jeong, Heon Sang
    • Journal of the Korean Society of Food Science and Nutrition
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    • v.42 no.11
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    • pp.1783-1791
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    • 2013
  • This study is investigated to evaluate the enhancement of antioxidant compound and activity of rough rice with different germination periods and high pressure treatment. The subject was germinated at $37^{\circ}C$ for 6 days (HP0), and then the germinated rough rice were subjected to 30 MPa for 24 hr (HP24) and 48 hr (HP48), respectively. HP0, HP24 and HP48 samples were prepared and extracted with 80% ethanol. The highest total polyphenol contents (5.15 mg/g) occurred in treating at HP48 after germination for 5 days. The total phenolic acid contents including gallic acid, chlorogenic acid, catechin, ${\rho}$-coumaric acid, ferulic acid, salicylic acid, naringin, myricetin, trans-cinnamic acid, naringenin and kaempferol increased from $37.26{\sim}204.32{\mu}g/g$ at HP0 to $77.29{\sim}283.05{\mu}g/g$ at HP48. In antioxidant activity analyses, HP48 extracts showed higher values in ABTS and DPPH radical scavenging activity, reducing power, and $Fe^{2+}$ iron chelating effect than those of the HP24 and HP0 extracts. These results suggest that the combined treatment of high pressure treatment and germination process efficiently enhanced antioxidant compound and activity of rough rice.

A Study on Applicability of Diversified Truck Weight-to-Power Ratios (표준트럭의 차별적 적용 방안 연구)

  • Oh Heung-Un
    • International Journal of Highway Engineering
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    • v.8 no.1 s.27
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    • pp.89-98
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    • 2006
  • The weight-to-power ratio of the standard truck for the climbing lane design is known to be 200lb/hp. The value was known to be assumed based on constant trucks' capability and regional distributions in stead of widely varied distributions region by region. Additionally, this value was assumed after investigating registered vehicles' statistics instead of investigating real portions of truck volumes. Therefore, it may be said that the value of the current standard truck does not reflect regional or industrial diversity and proportions of truck volumes. To resolve these issues, the present paper studies diversified standard trucks which consider regionally or industrially diversified and observed-volume based weigh-to-power ratios. For this purpose, individual trucks' weigh-to-power ratios obtained at toll-gates of national expressways were used. For regionally based study, the whole nation are divided into 8 regions, then each region is characterized by a unit of a weigh-to-power ratio. The applicability of each value is provided. Results show that the single value for the nationwide standard truck may be 208 lb/hp, 8 lb/hp higher than the current value of 200 lb/hp. Results also show that regional values ranged widely from 170 lb/hp to 230 lb, 30 lb/hp higher/lower than the current value. Conclusively, regional diversity of trucks' weigh-to-power ratios was identified then three types of standardized weigh-to-power ratios which may represent regional characteristics were suggested. As the diversified standard truck are applied to the design standard, two benefits are expected such as decrease of rear-end accident rates or decrease of climb lane construction costs.

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Quality Characteristics and Antioxidant Properties of Yanggaeng Supplemented with Hallabong Powder (한라봉 분말을 첨가한 양갱의 품질 및 항산화 활성)

  • Kim, Hyun Eun;Lim, Jeong Ah;Lee, Jun Ho
    • Journal of the Korean Society of Food Science and Nutrition
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    • v.44 no.12
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    • pp.1918-1922
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    • 2015
  • The feasibility of incorporating Hallabong powder (HP) as a value-added food ingredient into convenient food products was investigated using yanggaeng as a model system. HP was incorporated into yanggaeng at amounts of 0, 2, 4, 6, and 8% (w/w) based on total weight of cooked white beans and HP. pH level decreased while soluble solid content increased significantly with increasing levels of HP (P<0.05), whereas moisture content was not directly affected by level of HP incorporation. In terms of color, lightness decreased while redness and yellowness increased significantly (P<0.05) with increasing levels of HP. Hardness increased significantly when HP content exceeded 4% in the formulation (P<0.05). ABTS and DPPH radical scavenging activities were significantly elevated by HP addition, and they increased significantly as HP concentration increased in the formulation (P<0.05). Finally, consumer acceptance test indicated that the highest levels of HP incorporation (8%) had an adverse effect on general consumer preferences. In contrast, yanggaeng with moderate levels of HP (2%) is recommended based on its overall scores to take advantage of the antioxidant properties of HP without sacrificing consumer acceptability.

The Effects of Steeping and Cooking Pressure on Qualities of Cooked Brown Rice (침지조건과 압력이 현미의 취반특성에 미치는 효과)

  • Park, Jeong-Woo;Chae, Seon-Hee;Yoon, Sun
    • Journal of the Korean Society of Food Culture
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    • v.24 no.1
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    • pp.69-76
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    • 2009
  • This study was conducted to determine the optimal cooking conditions for brown rice using an electric pressure rice cooker. The effects of steeping conditions and cooking pressure on the hydration, gelatinization, texture and palatable properties of cooked brown rice were evaluated. Based on water uptake and DSC data, the optimal steeping time and temperature for brown rice were determined to be 25 minutes and ${\sim}60^{\circ}C$, respectively. The cooking conditions for brown rice were then divided into the following 6 categories: steeping at $25^{\circ}C$ for 25 minutes and cooking at an atmospheric pressure of 1.7 (25P) or 1.9 (25HP), steeping at $57^{\circ}C$ for 25 minutes and cooking at an atmospheric pressure of 1.7 (57P) or 1.9 (57HP), steeping at $85^{\circ}C$ for 15 minutes and cooking at an atmospheric pressure of 1.7 (85P) or 1.9 (85HP). The susceptibility of cooked brown rice starch to degradation into maltose by ${\alpha}$-amylase, which is related to the degree of gelatinization and in vitro digestibility, were then determined. The amount of maltose produced by cooked brown rice samples was highest in the 57HP group, followed by the 57P and 85HP groups. Storing cooked brown rice at $73^{\circ}C$ for 24 hours resulted in significantly higher amounts of starch being degraded into maltose in the 57P, 57HP and 85HP groups than in the other groups. Textural analysis demonstrated that the 57P, 57HP and 85HP groups had significantly lower gumminess and chewiness values when compared to the other groups, and that 57HP received had the lowest hardness of all treatments. These results were confirmed by the results of the sensory evaluations. Furthermore, the 57P and 57HP groups were found to have a higher glossiness, stickiness aroma and taste score than the other groups. These findings were taken to indicate that steeping conditions and pressure exerted a positive synergistic effect on the cooking quality of brown rice. The texture analyzer also revealed that storing the cooked rice at $73^{\circ}C$ for 24 hours only led to significantly lower scores in gumminess, hardness and chewiness in the 57P and 57HP groups, which indicates that these groups underwent a lesser degree of retrogradation than other groups. Taken together, the results of the present study demonstrate that steeping brown rice at $57^{\circ}C$ for 25 minutes and a higher cooking pressure improved the palatability and in vitro digestibility of brown rice significantly.

Development of Organization System for Health Management Program of Maternal-child in Public Health Centers (보건소 모성과 어린이 건강관리사업의 효율적 운영을 위한 조직구축 연구)

  • Hwang, Na-Mi;Park, Hyun-Tae
    • Research in Community and Public Health Nursing
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    • v.15 no.2
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    • pp.187-196
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    • 2004
  • Purpose: The purposes of this study are: to evaluate the effectiveness of organizations engaged in MCH programs; and to suggest the executive organizational system of maternal and child health (MCH) services linked to HP services at public health centers. Method: This study analyzes data on the present conditions and evaluates the organizational effectiveness of MCH workers at public health centers nationwide. The organizational effectiveness of MCH organization is assessed by MCH workers. Finally, this study seeks to obtain consensus among experts in the field of MCH. Result: The results are as follows. Of public health centers, 61.9% have a MCH organization for their MCH programs. For the other 38.2%, MCH services are undertaken by HP organization. Executive organizational systems for MCH services at leading MCH health centers are classified into three types: Type I (provides MCH and HP services through MCH organizations); Type II (provides MCH and HP Services through HP organizations) ; and Type III (provides MCH services through MCH organizations and HP services through HP organizations). The evaluation of the organizational effectiveness of MCH organizations shows that Type II is the most effective in terms of teamwork, autonomy, service quality and resource utilization. Conclusion: This study suggests that executive organizations for MCH and HP services for women and children should be established in accordance with lifetime health programs in order for public health centers to utilize the limited MCH and HP resources efficiently.

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