• Title/Summary/Keyword: 한국 고지도

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Anti-obesity Effects of Barley Sprout Young Leaf on 3T3-L1 Cells and High-fat Diet-induced Obese Mice (지방분화가 유도된 3T3-L1 세포와 고지방식이로 유도된 마우스에서 보리순 물추출물의 항비만 효과)

  • Kang, Byoung Man;Sim, Mi Ok;Kim, Min Suk;Yoo, Seung Jin;Yeo, Jun Hwan;Jung, Won Seok
    • Korean Journal of Medicinal Crop Science
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    • v.25 no.6
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    • pp.367-374
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    • 2017
  • Background: An imbalance in energy intake and expenditure can cause obesity, which is a major risk factor for chronic diseases such as heart disease, type 2 diabetes, insulin resistance, cancers and hyperlipidemia. Methods and Results: In this study, we evaluated the anti-obesity effects of a water extract from the young leaves of barley sprout (BS) in 3T3-L1 cells and in high-fat diet (HFD)-induced obese mice (HF). Lipid accumulation measurement indicates that BS markedly inhibited adipogenesis by reducing lipid droplet production in a dose-dependent manner. Furthermore, the mRNA expression of adipogenic transcription factors peroxisome proliferator-activated receptor-${\gamma}$ and fatty acid synthetase, CCAAT/enhancer binding protein-${\alpha}$ and fatty acid binding protein 4 in 3T3-L1 cells was significantly inhibited by BS treatment. In an in vivo test, the BS-administered group of HFD-induced mice showed less body weight gain, and lower liver and epididymal white adipose tissue weights. The BS-treated mice showed decreased serum levels of leptin and lipids compared to untreated HFD mice and the levels of adiponectin and the HDL-cholesterol/total cholesterol ratio increased. These results indicate that BS inhibits body fat accumulation by reducing the mRNA expression of lipogenesis transcription factors and increasing serum adipokine concentration in in vitro and in vivo tests. Conclusions: BS reduced high fat diet-induced weight gain and had a positive effect on dyslipidemia.

Antioxidant Activity of Rosa rugosa Thunberg and Effect on Serum Lipid Level in High Fat Diet-induced Mice (해당화 열매 추출 분말의 항산화 활성과 고지방 식이로 유도된 Mice의 혈청지질 수준에 미치는 영향)

  • Choi, Kyung-Soon;Kim, Yong-Hwan;Lee, Ki-Won;Shin, Kyung-Ok
    • The Korean Journal of Food And Nutrition
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    • v.28 no.2
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    • pp.320-327
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    • 2015
  • Since Korean ancient times, powder of Rosa rugosa Thunberg has been used as a folk remedy. This study was conducted to verify the effects of Rosa rugosa Thunberg powder on in vitro antioxidant properties and serum lipid levels of high-fat diet-induced mice from a nutritional viewpoint. In the case of Rosa rugosa Thunberg powders, measurement of TPC, ABTS radical scavenging activity of trolox, DPPH radical scavenging activity, and measured value of FRAP were higher in ethanol extract than water extracts. For LDL-cholesterol concentration, mice fed 10% powder of Rosa rugosa Thunberg with high-fat diets showed a high numerical value compared with other groups (p<0.05). When testing for triglyceride concentrations in blood, mice fed 10% and 20% powder of Rosa rugosa Thunberg with high-fat diets showed the lowest numerical values (p<0.05). When testing for blood insulin concentrations, the high-fat diet group showed higher levels than compared to the control group (p<0.05). When testing for blood leptin concentrations, the high-fat diet group was $5.88{\pm}3.53ng/dL$, whereas mice fed 10% powder of Rosa rugosa Thunberg with high-fat diets showed a blood leptin level of $10.36{\pm}5.96ng/dL$ (p<0.05). Therefore, results prove that powder of Rosa rugosa Thunberg reduces triglyceride concentrations in the blood, and could be used as an excellent natural antioxidant in the future.

A Study on the Fire Safety Measure of Pumped Storage Power Plant (양수발전소의 화재안전 대책에 관한 연구)

  • Kim, Yoo-Shik
    • Fire Science and Engineering
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    • v.20 no.4 s.64
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    • pp.125-130
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    • 2006
  • Pumped storage power plant is a system of generating electricity with hydroelectric power, in which at times of low electrical demand such as during nights, excess generation capacity of many power plants is used to pump water into the higher reservoir, and when there is higher demand, water is released back into the lower reservoir through a turbine, generating electricity. As pumped storage power plants across the nation are not on building registry under "the Article 6 of the Special Act by the Development of Power Resources", they are classified as a structure, not as a building. As a result, permit of fire protection facility is unnecessary, and fire protection administration is excluded from approval to completion of construction. Therefore, this study is to improve problems in accordance with the application of "he Article 6 of the Special Act by the Development of Power Resources", repair of facilities and problems with safety control to effectively prevent similar damages from repeatedly happening to pumped storage power plants in operation or under construction nationwide during a fire.

Quality Characteristics of Health Concerned Funtional Cookies using Crude Ingredients (거친재료를 첨가한 건강기능성 쿠키의 품질 특성 연구)

  • Kang, Nam-E;Kim, Hye-Young L.
    • Journal of the Korean Society of Food Culture
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    • v.20 no.3
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    • pp.331-336
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    • 2005
  • Pysicochemical and sensory characteristics of health concerned funtional cookies using various levels of crude ingredients of resistant starch were investigated in this study. The 10% substituted group had significantly higher pH values compared to those of control. Spread factor of control group had significantly the largest value and the 30% substituted group had the lowest values(p<0.05). Results of sensory characteristics showed significantly higher hardness, crispness and yellowness with 20% substituted sample group at p<0.05. Acceptance test of cookies with 10% substituted sample groups showed higher savory taste, texture, and overall acceptability and they did not show significant differences with the 20% substituted groups.

Anti-Diabetic and Anti-Inflammatory Effects of Purple Corn Extract in High-Fat Diet Induced Obesity Mice (고지방식이 비만 유도 마우스에서 자색옥수수 추출물의 항당뇨 및 항염증 효과)

  • Joung, Hyunchae;Kim, Chai-hee;Lee, Yejoo;Kim, Soon-kwon;Do, Myoung-Sool
    • The Korean Journal of Food And Nutrition
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    • v.30 no.4
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    • pp.696-702
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    • 2017
  • Metabolic syndrome, including obesity, glucose intolerance and elevated blood pressure, is related to type 2 diabetes and cardiovascular disease. Previous studies have reported the anti-oxidative, anti-inflammatory and anti-diabetic effects of purple corn extract. We investigated the efficacy of purple corn extract (PC) against high-fat diet (HFD)-induced obesity and glucose intolerance, and examined the underlying mechanisms by analyzing expression of proteins and genes involved in glucose regulation and macrophage infiltration. C57BL/6 mice were fed with normal chow diet (ND), or HFD treated with distilled water (DW, control) or PC, for 10 weeks. Although body weights were similar in the HFD-fed groups, we observed a decrease in the liver and epididymal adipose tissue (EAT) weights, and enhanced glucose tolerance test (GTT) results in the PC group, as compared with DW group. Liver showed increased Akt phosphorylation in the PC-treated mice; however, no changes were observed in the EAT, for all groups. In PC-treated mice, decreased macrophage infiltration was seen in the EAT, with a reduced expression of macrophage marker genes. Finally, proinflammatory cytokine gene expressions were decreased by PC in the EAT, and a modest trend for downregulation was observed in the liver. Hence, we conclude that PC may decrease glucose intolerance by increasing the phosphorylation of Akt and reducing the macrophage infiltration into the EAT.

Effects of Fly Maggot Extracts on the Liver and Plasma Lipid in Rat Fed High-Fat Diets (고지방식이 유도된 흰쥐의 혈액지질 및 간에 관한 파리유충 추출물의 효과)

  • Park, Byung-Sung
    • Journal of the Korean Applied Science and Technology
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    • v.27 no.3
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    • pp.290-299
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    • 2010
  • The bioactive effects of ethanol extracts from fly maggot (ME) on reduction of plasma lipids levels in rats fed high-fat diets (Expt. Ⅰ), and on liver function recovery of hepatotoxicity rats by intraperitoneal injection of carbon tetrachloride ($CCl_4$) or by orally administration of alcohol (Expt. II) were investigated. In expt. I, twenty seven, male rat SDS(sprague dawley strain) were randomly assigned to three treated groups, including normal control group, HF (group with high fat diets which have no extracts) and HFE (HF plus orally administered doses of ME extract at 5.0 mg/100g of body weight). In expt. II, forty five, male rats (SDS) were randomly assigned to each of the five groups: T1 (control), T2 (intraperitoneal injection of $CCl_4$), T3 (intraperitoneal injection of $CCl_4$ after orally administered with ME), T4 (orally administered with combination of ME and alcohol), T5 (orally administration of ME after orally administered with alcohol). There were significant decreases in plasma (TAG), (TC), (LDL-C) in the HFE group with orally administered doses of ME at 5.0 mg/100g of body weight, respectively, however, the (HDL-C) were significantly increased in HFE group as compared to HF group with high fat diets which have no extracts (p<0.05). The levels of aspartate aminotransferase (AST), alanine aminotransferase (ALT), ${\gamma}$-glutamyl transferse(${\gamma}$-GTP) and bilirubin were highest in T2 or T3, and high in order T4 or T5, and lowest in T1 except for bilirubin which has same with T4, T5 (p<0.05). The high recovery of liver damage by $CCl_4$ from the light microscopic appearance was observed in rats (T3) with extracts, and also high in T4 than T5 by orally administrated with alcohol. In conclusion, the ethanol extracts from fly maggot may have a bioactive effects to prevent for human lipids disorder and alcoholic disease.

Effect of Potato Polyuphenolics on the Hyperlipidemia in Rats (식이성 고지혈증에 미치는 감자 폴리페놀의 영향)

  • 조영수;차재영
    • Journal of the Korean Society of Food Science and Nutrition
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    • v.29 no.2
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    • pp.274-279
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    • 2000
  • Effect of potato polyphenolic compound on the concentrations of serum and liver lipids, serum glucose, and urine protein was investigated in Sprague Dawley rats by feeding a diet containing 0.5% of cholesterol for 2 weeks. Polyphenolic compound extracted from potato (Solanum tuberosum variety Dejima) was supplemented at a 0.5% level in the basal diet or the cholesterol diet. The supplementation of potato polyphenolic compounds decreased slightly the concentrations of total cholesterol and VLDL+LDL-cholesterol in serum, and atherosclerotic index in rats fed the cholesterol diet, while those measurements were not altered by the supplementation of potato polyphenolic compounds in rats fed the basal diet. In the rats fed the basal diet or the cholesterol diet containing potato polyphenolic compounds, urine protein increased by 12% and 27% at 1st week, respectively, but this change was not seen at 2nd week. The concentration of serum glucose, however, was not significantly different in the dietary groups.

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A Study on the Comparison of Spatial Evapotranspiration between SEBAL and SWAT model results (SEBAL 모형과 SWAT 모형의 공간 증발산량 산정결과 비교 연구)

  • LEE, Yong-Gwan;JUNG, Chung-Gil;AHN, So-Ra;KIM, Seong-Joon
    • Proceedings of the Korea Water Resources Association Conference
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    • 2015.05a
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    • pp.470-470
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    • 2015
  • 본 연구의 목적은 위성영상 기반의 SEBAL(Surface Energy Balance Algorithm for Land) 모형과 SWAT(Soil and Water Assessment Tool) 수문모형을 용담댐 유역($922.3km^2$)에 적용하여 증발산량을 산정하고 모형 간 공간 증발산량의 비교를 통해 각 모형의 적용성을 평가하는데 있다. 이를 위해 SEBAL모형의 입력자료로 Terra MODIS(Moderate Resolution Imaging Spectrometer) Product 중 Normalized Distribution Vegetation Index(NDVI), Albedo 영상을 2012년부터 2013년까지 월단위로 구축하고, 일단위의 Land Surface Temperature(LST) 영상을 구축하였다. 지형자료로는 Digital Elevation Model(DEM)과 Land use를 구축하였으며 SEBAL 모형의 구동을 위한 위성영상 및 지형자료는 500 m의 공간해상도로 재구축하였다. SWAT 모형의 모의를 위해 기상 및 유량 자료를 2000년부터 2013년까지 일단위로 구축하였고, DEM, Land use, 토양도의 지형자료를 30 m의 공간해상도로 구축하였다. SWAT 모형의 유출 검보정 후 수위관측소 지점에서 평균 $R^2$를 산정한 결과 도치(0.80), 동향(0.72), 석정(0.64), 주천(0.80), 천천(0.80), 용담댐(0.72)로 높은 상관성을 나타냈으며, 유출 검보정 후 SWAT 모형의 증발산량 모의 결과를 바탕으로 SEBAL 모형과의 공간 증발산량을 비교하였다. 두 모형의 증발산량은 SEBAL 모형의 경우 지형에 따라 SWAT 모형은 토양 특성에 따라 분포하는 경향이 다르게 나타났다. SEBAL 모형은 주로 저지대에서 증발산량이 높게 산정되며 고지대로 갈수록 감소하여 증발산량이 지형의 고저차에 따라 분포하는 모습을 보였다. SWAT 모형은 토양 특성에 따라 증발산량이 분포하며 유역 내에서 뚜렷한 차이를 나타내지는 않았다. 월별 총 증발산량은 SWAT 모형의 경우 7~8월에 약 90 mm/mon로 가장 높게 나타나고 1~2월은 0 mm/mon로 계절별 변화폭이 컸으나, SEBAL 모형의 경우 5~6월에 증발산량이 약 60 mm/mon로 가장 높게 나타났고 계절별 변화 폭이 SWAT 모형에 비해 적은 모습을 보였다. 이는 위성영상을 기반으로 하는 SEBAL 모형의 특성상 장마 기간에 해당하는 7~8월은 구름으로 인해 일사량이 적게 계산되고, 그 결과 5~6월에 비해 증발산량이 작게 산정되는 것으로 판단된다.

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Hydraulic stability evaluation for deep tunnel on continuous precipitation (연속강우에 대한 대심도 터널의 수리적 안정성 평가)

  • Oh, Jun Oh;Park, Jae Hyeon;Park, Chang Keun;Jun, Sang Mi
    • Proceedings of the Korea Water Resources Association Conference
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    • 2016.05a
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    • pp.99-99
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    • 2016
  • 최근 홍수의 특성과 피해 양상은 과거와는 다르게 변화하고 있으며, 급격한 도시화로 인하여 기존 하천유역의 저류 능력이 감소하였는데 이러한 한계를 극복하기 위하여 이미 외국에서는 대심도 터널을 활용한 홍수재해 관리방안이 오래전부터 활용되어 왔다. 본 연구에서는 현재 서울시에 건설중인 '신월 빗물저류배수시설' 연속강우 시 대심도 터널의 수리적 안정성 평가와 운영방안 수립을 위한 수리모형실험을 실시하였다. 모형은 Froude 상사법칙을 사용하여 원형의 1/50크기로 제작하였다. 모형의 전체 저류 가능량은 모형기준 $2.78m^3$ (원형 $347,778m^3$)이며, 터널 내 잔류수는 전체 저류 가능량의 0 ~ 100%까지 10%씩 변화시켜 실험 CASE를 선정하였다. 각 실험CASE별 수직 유입구 안정성 평가를 실시한 결과 터널 내 잔류수가 10%~80%까지 존재 할 때는 저지수직구1에서의 압축공기 폭발현상으로 인한 월류현상이 발생하였으며, 10%~40%까지는 저지수직구2에서 월류현상이 발생하였다. 하지만 고지수직구에서는 모든 CASE에서의 공기폭발 현상 및 월류현상이 발생하지 않아 유입성능 및 공기배출 성능이 충분히 발휘되고 있는 것으로 분석되었다. 또한 저지수직구1에서의 월류현상 발생 시점은 5분55초에서 3분42초까지 빨라졌으며 저지수직구2에서의 월류현상 발생 시점은 5분57초에서 4분57초로 빨라졌다. 이는 터널 내 잔류수량이 증가할수록 터널 내 만관시점이 빨라져 발생하며, 저지수직구1,2에서의 압축공기 폭발현상 및 월류 현상은 터널 내에서 발생한 반사파의 영향으로 판단된다. 차후 터널 내 반사파 발생에 대한 연구가 추가적으로 진행되어야 할 것이다.

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Estimation of phased warning water level for flood warning in disaster prone area in Busan (부산광역시 재난취약지역의 홍수 예·경보 발령을 위한 단계별 기준수위 산정)

  • Yoon, Eui Hyeok;Lee, Jae Hyeok;Lee, Yeong Gon;Shin, Hyun Shuk
    • Proceedings of the Korea Water Resources Association Conference
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    • 2016.05a
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    • pp.266-266
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    • 2016
  • 2014년 8월 25일 시간당 130mm 이상의 폭우로 인하여 부산시 중구를 제외한 부산 전역에 걸쳐 인명 및 막대한 재산피해가 발생하였다. 이는 부산광역시의 지형특성상 고지대에 주택 등이 조밀하게 개발되어 불투수층의 증가 및 배수처리의 한계로 침수지역이 다량 발생하였고, 절개지 및 옹벽 등이 많은 지역, 소하천 및 산업단지 조성 후 지반이 약화된 지역 등에서 주로 피해가 발생하였다. 따라서 부산지역에서 도시홍수로 인한 막대한 피해를 입은 기장군과 부산광역시 일부 유역에 대하여 홍수 예보 시설을 설치 운영하기 위하여 체계적이고 효율적인 재해관리 방안을 마련하고자 하였다. 재난취약지역으로 선정된 기장군 일대와 부산광역시 일대의 총 10개 지점(14개소)에 대하여 현장 조사를 실시하여 수위관측시스템 설치를 위한 적절 지점을 선정하였으며, 이를 바탕으로 각 지점에 대하여 수리모형(HEC-RAS)을 구축하였다. 수리모형에서 산출된 결과를 바탕으로 도시 하천의 현실에 맞는 홍수 예 경보 발령을 위한 각 각의 4단계 기준수위(둔치위험 수위, 주의보 수위, 경보 수위, 하천범람 위험 수위)를 산정하였다. 그리고 각 지점별로 산정된 단계별 기준 수위를 이용하여 재난취약지역으로 선정된 기장군 6개 지점과 부산광역시 4개 지점에 대하여 "홍수 예 경보 발령을 위한 기준 수위 산정 결과"를 도출하였고, 위 결과를 바탕으로 부산광역시에 홍수 예 경보 발령을 위한 시스템을 구축하여 도심 재난 예방에 활용하도록 하였다. 또한 위 지점에 대하여 지속적인 하천 정비 등의 사후 관리 방안을 제시하였으며, 향후 부산광역시의 다른 재난취약지역에 대하여 보다 개선된 홍수 예 경보 시스템을 구축하여 현재 국가하천에 대하여 시행되고 있는 홍수 예보와 같은 재난 예방 시설의 구축과 국민의 생명과 재산을 보호할 수 있는 체계적인 대응 방안 마련에 기여하고자 하였다.

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