• Magazine of RCR
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• v.15 no.2
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• pp.35-38
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• 2020

• Journal of Environmental Science International
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• v.32 no.4
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• pp.259-266
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• 2023

Today, environmental pollution has been found to be one of the causes of various diseases, including brain and nervous system diseases. In particular, neurodegenerative diseases have been found to be caused by hyperactivation of immune system cells such as microglia. Preventive and therapeutic measures are needed to suppress them. Hirudo is known as a traditional herbal medicine, based on its multiple biological activities such as anti-eczema and anti-coagulation. In the present study, the anti-neuroinflammatory potential of hirudo extract was investigated in lipopolysccharide (LPS)-stimulated BV2 microglial cells and in mice. Hirudo extract significantly inhibited LPS-stimulated nitric oxide (NO) production and cytokine (IL-1Ra, KC, MCP-5, and RANTES) expression in a dose-dependent manner without causing cytotoxicity. Pretreatment with hirudo extract suppressed LPS-induced NF-κB p65 nuclear translocation. Moreover, hirudo extract reduced LPS-stimulated microglial acitivation and improved memory impairments. The results demonstrated that hirudo extract exerts anti-neuroinflammation activities, partly through inhibition of the NF-κB signaling pathway. These findings suggest that hirudo extract might have therapeutic potential with respect to neuroinflammation and neurodegenerative diseases.

• Proceedings of the Korean Operations and Management Science Society Conference
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• 1993.04a
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• pp.151-157
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• 1993

본 연구에서는 산.학.연 협동을 통해 기술실용화와 중소기업창업을 촉진하는 효과적인 추진방법의 하나로, 대학캠퍼스나 인근지역에 "기술창업.개발센터"(Technology Business Development Center: TBDC)를 설립하는 방안을 제시하고, 구체적인 기술창업.개발센터의 개념과 체계, 설립운영방안, 우리나라에서의 효과적인 추진전략을 제시한다. 특히 국가적 차원에서 TBDC를 지방대학들을 중심으로 한 지역기술개발센터(Regional Technology Center:RTC)의 형태로 전국 각 지역에 설립하여 육성하되, 공개경쟁을 통해 선별적으로 TBDC를 지정할 것을 제의한다. 아울러 정부의 TBDC지원유형과 TBDC의 단계별 육성방안도 제시한다.성방안도 제시한다.

• Proceedings of The Korean Society of Agricultural and Forest Meteorology Conference
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• 2018.06a
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• pp.80-81
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• 2018

• Proceedings of The Korean Society of Agricultural and Forest Meteorology Conference
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• 2015.08a
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• pp.31-34
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• 2015

• Journal of the Korean Society for information Management
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• v.36 no.3
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• pp.203-228
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• 2019

This study developed KISTI CLCM, a curation model suitable for the content life cycle, focusing on the KISTI Content Curation Center. For developing the KISTI Curation Model, the previously developed models DCC, DCC&U, UC3 and DCN models were reviewed and the advantages of the models connected to the mission and tasks of the digital curation center were derived. Interviews with staffs of the KISTI Content Curation Center identified the characteristics of the content and identified the level of achievement of the current task. In addition, this study proposed to enhance usability by developing KISTI content curation waves based on the UC3 model to discover user-centered services and add new values to digital resources.

• Journal of the Korean Society of Manufacturing Process Engineers
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• v.18 no.8
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• pp.98-103
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• 2019

A more accurate method of feature point extraction and matching for three-dimensional reconstruction using low-resolution images of crops is proposed herein. This method is important in basic computer vision. In addition to three-dimensional reconstruction from exact matching, map-making and camera location information such as simultaneous localization and mapping can be calculated. The results of this study suggest applicable methods for low-resolution images that produce accurate results. This is expected to contribute to a system that measures crop growth condition.

• Journal of the Korean Society of Manufacturing Process Engineers
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• v.20 no.10
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• pp.80-87
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• 2021

Our study introduces an improved modular agricultural platform to provide convenience to agricultural workers. We upgrade the platform design in three parts, namely, by adding a 458 pattern tire, electricity control, and four-wheel steering function, to improve the platform performance. Results showed that the upgrades enhanced the platform performance and reduced its overall weight as compared with the existing platform. To demonstrate the performance of our improved platform, we conducted five types of experiments with respect to the climbing angle, variable width, attitude control, speed, and obstacle passing.

• Journal of the Korean Society of Manufacturing Process Engineers
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• v.20 no.9
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• pp.70-75
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• 2021

We developed a platform that was capable of autonomous steering in a furrow environment. It was developed to autonomously control steering by recognizing the furrow using a laser distance, three-axis tilt, and temperature sensor. The performance evaluation indicated that the autonomous steering success rate was 99.17%, and it was possible to climb up to 5° on the slope. The usage time was approximately 40 h, and the maximum speed was 6.7 km/h.

• Journal of the Korean Society of Manufacturing Process Engineers
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• v.21 no.9
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• pp.92-97
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• 2022

In this paper, as a research on autonomous steering for agriculture, a sensor module for furrow recognition was developed through a low-cost distance sensor combination. The developed sensor module was applied to the vehicle, and when driving in a furrow curve, the autonomous steering success rate was 100% at a curvature of 20 m or more, and 70% at a curvature of 15 m or less. The self-steering success rate according to the ground condition showed a 100% success rate regardless of soil, weeds, or mulching film.