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Effects of SPAC1B3.08, ortholog of Thp1/PCID2, on mRNA export in fission yeast (분열효모에서 Thp1/PCID2의 이종상동체인 SPAC1B3.08이 mRNA 방출에 미치는 영향)

  • Park, Jin Hee;Yoon, Jin Ho
    • Korean Journal of Microbiology
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    • v.55 no.2
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    • pp.112-116
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    • 2019
  • Thp1/PCID2 is a subunit of the evolutionally conserved TREX-2 complex, which is required for transcription-coupled mRNA export from the nucleus to the cytoplasm. In fission yeast, Schizosaccharomyces pombe, there are two orthologs of the Thp1/PCID2 protein. In addition to pci2 (SPBC1105.07c) gene, SPAC1B3.08 gene encodes a PCI domain-containing protein that is predicted as a component of TREX-2 complex. Overexpression of SPAC1B3.08 cause slight defects of both growth and mRNA export. Yeast two-hybrid and co-immunoprecipitation analysis exhibits that the SPAC1B3.08 protein interacted with Sac3 and Dss1, which are another components of TREX-2 complex. These observations support the possibility that the S. pombe SPAC1B3.08 protein, as a component of TREX-2 complex, is involved in mRNA export.

A Tensor Space Model based Deep Neural Network for Automated Text Classification (자동문서분류를 위한 텐서공간모델 기반 심층 신경망)

  • Lim, Pu-reum;Kim, Han-joon
    • Database Research
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    • v.34 no.3
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    • pp.3-13
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    • 2018
  • Text classification is one of the text mining technologies that classifies a given textual document into its appropriate categories and is used in various fields such as spam email detection, news classification, question answering, emotional analysis, and chat bot. In general, the text classification system utilizes machine learning algorithms, and among a number of algorithms, naïve Bayes and support vector machine, which are suitable for text data, are known to have reasonable performance. Recently, with the development of deep learning technology, several researches on applying deep neural networks such as recurrent neural networks (RNN) and convolutional neural networks (CNN) have been introduced to improve the performance of text classification system. However, the current text classification techniques have not yet reached the perfect level of text classification. This paper focuses on the fact that the text data is expressed as a vector only with the word dimensions, which impairs the semantic information inherent in the text, and proposes a neural network architecture based upon the semantic tensor space model.

Utilizing Purely Symmetric J Measure for Association Rules (연관성 규칙의 탐색을 위한 순수 대칭적 J 측도의 활용)

  • Park, Hee-Chang
    • Journal of the Korean Data Analysis Society
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    • v.20 no.6
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    • pp.2865-2872
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    • 2018
  • In the field of data mining technique, there are various methods such as association rules, cluster analysis, decision tree, neural network. Among them, association rules are defined by using various association evaluation criteria such as support, confidence, and lift. Agrawal et al. (1993) first proposed this association rule, and since then research has been conducted by many scholars. Recently, studies related to crossover entropy have been published (Park, 2016b). In this paper, we proposed a purely symmetric J measure considering directionality and purity in the previously published J measure, and examined its usefulness by using examples. As a result, it is found that the pure symmetric J measure changes more clearly than the conventional J measure, the symmetric J measure, and the pure crossover entropy measure as the frequency of coincidence increases. The variation of the pure symmetric J measure was also larger depending on the magnitude of the inconsistency, and the presence or absence of the association was more clearly understood.

PVA-based Graft Copolymer Composite Membrane Synthesized by Free-Radical Polymerization for CO2 Gas Separation (자유 라디칼 중합법을 활용한 CO2 기체분리용 PVA 기반 가지형 공중합체 복합막)

  • Park, Min Su;Kim, Jong Hak;Patel, Rajkumar
    • Membrane Journal
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    • v.31 no.4
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    • pp.268-274
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    • 2021
  • One of the chronic problems in the issue of global warming is the emission of greenhouse gases. Carbon dioxide (CO2), which accounts for the highest proportion of various greenhouse gases, has been continuously researched by humans to separate it. From this point of view, a poly(vinyl alcohol) (PVA)-based copolymer with acrylic acid monomer was utilized in a gas separation membrane in this study. We employed a free radical polymerization to fabricate PVA-g-PAA (VAA) graft copolymer. It was utilized in the form of a composite membrane on a polysulfone substrate. The proper amount of acrylic acid reduced the crystallinity of PVA and increased CO2 solubility in separation membranes. In this perspective, we suggest the novel approach in CO2 separation membrane area by grafting and solution-diffusion.

Development of the Highly Dispersed Palladium-Nickel Catalysts for Catalytic Partial Oxidation of Methane (메탄 부분산화 반응을 위한 고분산된 팔라듐-니켈 촉매 합성 및 반응)

  • Lee, Seunghyun;Jeon, Jonghyun;Kim, Juchan;Ha, Kyoung-Su
    • Korean Chemical Engineering Research
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    • v.59 no.2
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    • pp.269-275
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    • 2021
  • In this study, ordered mesoporous silica-supported Ni catalysts were prepared for catalytic partial oxidation of methane (CPOM) by using electroless nickel plating method. Unlike conventionally impregnated catalysts, the electrolessly-plated nickel catalyst showed that nickel was highly dispersed and formed stably on silica-supported surface. It was verified by TEM-EDS analysis. During the activity tests, the electrolessly-plated nickel was barely sintered and the amount of carbon deposition was very small. Consequently, the catalyst was far less deactivated, while the sintering was significantly observed in the cases of the catalysts prepared by the conventional impregnation method. Regarding the palladium-promoted catalysts, the reducibility of nickel was increased, and the reaction performances were enhanced in terms of CH4 conversion and H2/CO ratio of produced syngas.

A Study of the Development of Gardening Products Converged with Cultural Contents of Kongjwi Patjwi (콩쥐 팥쥐전의 문화콘텐츠를 융합한 가드닝 제품 개발 연구)

  • Choi, Jung-Hwa;Lee, Myung-Ah
    • Journal of Digital Convergence
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    • v.17 no.11
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    • pp.501-508
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    • 2019
  • Today, home gardening is in the spotlight. Therefore, the necessity of developing a new type of gardening product was raised according to the consumer's desires. This study, the contents were developed using sparrows, a helper who helped the bean rat's grain-cracking task among the characters of 'kongjwi patjwi'. The cultural contents convergence product is a lid production that is used at the end of the plant support. The fabrication method was designed using UG NX program after design research, and after printing by 3D polyjet method, mold was made and cast into silicon and resin. Through product manufacturing, we could confirm the public's interest in the possibility of new products and creativity. In the future, it is expected that the development of products incorporating cultural contents through various cultural archetypes will be activated, contributing to the enhancement of economic added value and national brand value.

Motivation and Meaning of the Elderly Women's Line Dance Experience (여성 노인의 라인댄스 체험 동기와 의미 탐색)

  • Kim, Young-Mee;Oh, Jin-Sook
    • Journal of Digital Convergence
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    • v.19 no.2
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    • pp.471-479
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    • 2021
  • The purpose of this study is to find out what meanings would be brought to the old females' lives, who took part in the line dance as programs for senior's health. 6 the old females were selected. Research materials were gathered from in-depth interviews and observations by researcher. As a result of content analysis, the following conclusions were drawn. First, elderly's motives for participation in line dance were found to be solicitation of the surroundings, recovery and maintenance of health, and participation in pursuit of happiness. Second, the elderly's line dance experience was changed the perception of dance. Third, line dance improved interest and confidence in the body and appearance. Fourth, the line dance experience provides a space for making new friends. Fifth, the line dance experience improved a sense of accomplishment and immersion through dance. Sixth, the support and praise of the family increased self-esteem and improved overall life satisfaction and happiness.

Predictive Model for Quality of Life of the Older Men Living Alone (남성 독거노인의 삶의 질 예측모형)

  • Kim, Su Jin;Jeon, Gyeong-Suk
    • Journal of Korean Academy of Nursing
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    • v.50 no.6
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    • pp.799-812
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    • 2020
  • Purpose: This study aimed to construct and test a predictive model that explains and predicts the quality of life in older men living alone. Methods: A self-report questionnaire was used to collect data from 334 older adult men living along aged 65 years or over living in Jeollanam-do provinces. The endogenous variables were depression, self-rated health, instrumental activity of daily life, health promotion behaviors, the number of social participation activities and quality of life. Data were analyzed using the SPSS 21.0 and AMOS 21.0 programs. Results: The final model with 14 of the 8 analysed paths showed a good fit to the empirical data: χ2 = 173.26(p < .001, df = 53), normed χ2 = 3.27, GFI = .92, NFI = .90, CFI = .93, TLI = .89, RMSEA = .08 and SRMR = .06. Activities had direct effect on quality of life of older men living alone and social support had both direct and indirect effects. Meanwhile, function and socioeconomic status showed only indirect effects. The variables included in the eight significant paths explained 83.7% of variance in the prediction model. Conclusion: Instrumental activities of daily living and social support effect directly on quality of life in the older men living alone. Findings suggest that health care providers including community nurses need to provide social support as well as empowerment programs of instrumental activities of daily living and health promotion for improving quality of life of the older men living alone.

A Study on Inductive Power Line Communication with Metal Block Channel (금속블록 채널이 있는 유도형 전력선통신에 관한 연구)

  • Sohn, Kyung-Rak;Kim, Hyun-Sik
    • Journal of IKEEE
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    • v.25 no.1
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    • pp.95-100
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    • 2021
  • If we know the location of the hull block and the welding feeder in the shipyard, we can easily obtain the location information of the worker. That data is very useful for implementing a workplace safety monitoring system. However, it is difficult to apply a fixed communication network to the workplace due to the specificity of the hull structure and welding process. In this study, inductive power line communication, which can replace dedicated communication line, was reviewed. A ferrite core was used as an inductive coupler to be installed on the power cable of the welding machine, and a nano-crystalline core was applied as a coupler to be fastened to the support rod of the metal block. In order to visualize the operating principle of the proposed couplers, 3D modeling and finite element analysis were performed with the COMSOL AC/DC module. In the communication performance test using an aluminum profile, when the communication channel was formed by the contact of the welding electrode, the bandwidth was kept above 6 Mbps.

Die Genehmigungsfiktion im deutschen VwVfG (독일 행정절차법상의 허가의제제도와 그 시사점)

  • Kim, Jung-Kwon
    • Journal of Legislation Research
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    • no.54
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    • pp.39-69
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    • 2018
  • In $j{\ddot{u}}ngster$ Zeit wird eine Fiktion im Verwaltungsrecht als essentielles Instrument $f{\ddot{u}}r$ Deregulierung sowie Verwaltungsvereinfachung mehr und mehr ins Feld $gef{\ddot{u}}hrt$ und ihre Erweiterung gefordert, weil sie in der Regel auf das Zeitsparen durch Verfahrenswegfall zielt. In Deutschland $erh{\ddot{o}}hte$ sich eine Bedeutung der Genehmigungsfiktion, indem sie durch 4.Novelle des VwVfG, die bei der Umsetzung der Richtlinie 2006/123/EG $ben{\ddot{o}}tigt$ wurde, als ein allgemeines verwaltungsrechtliches Rechtsinstitut eingeordnet wird. In Korea gibt es $vielf{\ddot{a}}ltige$ Fiktionsmethode, $w{\ddot{a}}hrend$ im deutschen Recht die Fiktion lediglich darin besteh, nach Ablauf der festgesetzten Frist die Entscheidung bzw. den Verwaltungsakt anzunehmen. Die systematische und logische Festsetzung der Fiktionslehre in Korea ist erforderlich. Deshalb wird eine allgemeine Regel zur Fiktion durch eine Kodifikation des allgemeinen Verwaltungsgesetzes, wie VwVfG, gefordert.