• Clinical and Experimental Pediatrics
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• v.46 no.6
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• pp.576-584
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• 2003

Purpose : For the early diagnosis of Henoch-Schonlein purpura(HSP) presenting with acute abdominal pain preceding skin rash. Methods : The clinical, endoscopic and radiological records of 23 cases of HSP, presenting with gastrointestinal symptoms preceding skin rash were reviewed. Results : The intervals from the onset of abdominal pain to the development of the skin rash were one day to 30 days(median five days), most of them were within two weeks. The presenting abdominal symptoms were abdominal pain(23 cases), vomiting(16 cases), hematochezia or melena(eight cases) and hematemesis(three cases). The abnormal endoscopic findings include coalescing erythematous lesions, areas of submucosal hemorrhage and superficial erosions and ulcers. The upper gastrointestinal endoscopy showed the abnormalities in 21 of 23 cases, which were observed in the duodenum( 21 cases), the stomach(12 cases) and the esophagus(one case). Duodenitis with hemorrhage and/or erosions in the descending duodenum was the sole endoscopic abnormality in two cases and was the most marked finding in three cases. Sigmoidoscopy showed the abnormalities in six of eight cases. The abdominal ultrasonogram showed abnormalities in 12 of 17 cases, which included small bowel wall thickening(eight cases) and intramural hemorrhage(three cases). Recurrences after three months of symptom free intervals developed in four cases; three of them had persistent nephritis beyond one year. Conclusion : The erosive hemorrhagic duodenitis in the descending duodenum in the upper endoscopy and the small bowel wall thickening in the abdominal ultrasonogram can be useful findings in the diagnosis of HSP presenting with acute abdomen.

• Korean Journal of Food Science and Technology
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• v.37 no.6
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• pp.989-996
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• 2005

Ultraviolet (UV) induces photo aging, erythema, sunburn, photo-toxicity, photo-allergy, and skin tumor, To investigate photo-protective effects of AmorePacific Beauty-03 (APB-03; mixture of red ginseng extract powder and soybean extract powder) on UV-induced damaged skins, 40 SKH hairless female mice were orally administered APB-03 or saline five times a week and irradiated with UV three times per week far up to 12 weeks. Visible skin changes and skin damage in dermis and epidermis by replica image analysis and histological analysis. In APB-03-treated group, better skin, negative replica appearance and less wrinkle formation were observed compared to the UV control group. These results demonstrate oral administration of APB-03 have photo-protective effects on UV-damaged hairless mouse skin.

• Food Science and Preservation
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• v.20 no.4
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• pp.583-591
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• 2013

Atopic dermatitis (AD) is a common chronic inflammatory disease associated with a cutaneous hypersensitivity reaction to an allergen. Although the incidence of AD is increasing these days, therapeutics has yet to be developed for its treatment. The aim of this study was conducted in order to compare and investigate the characteristic between the Castanea crenata inner shell extract (CS) and the Castanea crenata inner shell extract fermented by Lactobacillus bifermentans (FCS) for an anti-atopic medication. The total polyphenol and flavonoid contents were similar to CS and FCS. In the DPPH and superoxide anion radical scavenging, the CS and FCS had the potential for antioxidant activities. Both of them did not exhibit cytotoxicity to HS68 cells. The evaluation of the anti-inflammatory activity in Raw264.7 cells demonstrated that the FCS has inhibited the LPS-induced production of nitric oxide as compared to the CS. The anti-atopic dermatitis test was done through the induction of DNCB in AD hairless mice. The FCS has inhibited the development of the atopic dermatitis-like skin lesion by transdermal water loss, melanin and erythema of the skin as compared to the CS. Moreover, the pro-inflammatory cytokine IL-$1{\beta}$ and TNF-${\alpha}$ production in hairless mice were inhibited by the FCS treatment. It indicates that the fermentation of the Castanea crenata inner shell has the potential for the treatment of atopic dermatitis.

• Pediatric Infection and Vaccine
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• v.14 no.2
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• pp.188-193
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• 2007

Varicella-zoster virus is a human herpesvirus that causes chickenpox (varicella), becomes latent in cranial nerve and dorsal root ganglia, and frequently reactivates to produce shingles (zoster) and postherpetic neuralgia. Varicella zoster meningitis is a rare complication after varicella zoster infection. It usually affects a patient of immunocompromised or impaired cellular immunity, is rare in a immunocompetent child. We report two cases of aseptic meningitis in association with varicella zoster, not having any complication in the immunocompetent children.

• Investigative Magnetic Resonance Imaging
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• v.10 no.2
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• pp.117-120
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• 2006

Atretic cephalocelces are defined as skin-covered midline subscalp lesions that contain meninges and rest of glial and/or central nervous system tissue. When the straight sinus is absent or rudimentary, the falcine sinus can be recanalized to enable venous drainage. Although the atretic cephalocele or persistent falcine sinus has largely been described in the pediatric population, it is a rarely observed in the adult population. We report a unique case of spontaneously involuted atretic cephalocele coexistent with persistent falcine sinus in an adult. MR images and MR venography were useful for diagnosis and accurate anatomical depiction.

• Fashion & Textile Research Journal
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• v.8 no.5
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• pp.571-576
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• 2006

Thirty P. acnes were isolated from the 30 acne patients who visited some skin care shops from Feburary of 2001 to August of 2001. They were identified by morphological features (gram stain), biochemical properties. Only P. acne strains are isolated among Propionibacteria sp. and biochemical properities of P. acnes were not different from P. acnes ATCC 11827 strain significantly. The results of the biotyping was as follow: twenty three strains of biotype I from comedone, 1 strain of biotype II from pauple, 5 strains of biotype III from pauple and pustule, and 1 strain of biotype IV from pauple were isolated respectively.

• Journal of Veterinary Clinics
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• v.11 no.1
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• pp.343-346
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• 1994

Microsporum gypseum was identified as the prime cause of dermatitis in two young horses who were housed in unhygienic stables. The lesions were mainly distributed on the thorax, abdomen and rump. The diagnosis was established on the direct demonstration of dermatophyte in the cutaneous lesions and isolation of the fungus in pure and heavy growth from the infected hairs and skin scales on mycological medium at 3$0^{\circ}C$. Microscopoc morphology of the isolate in 'PHOL' stain many macroconidia and few microconidia. Epidemoilogical investigation revealed the prevalence of M. gypseum in the soil of stables. Mycological examination is highly imperative to distinguish the disease from other dermatological disorders. This apperas to be the first report of equine dermatitis due to M. gypseum in Westenn India.

• Journal of Veterinary Clinics
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• v.7 no.2
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• pp.521-525
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• 1990

The present investigation confirms the zoonotic significance of Microspoum canis infection in five patients who had direct contact with diseased dogs and cats. Typical ringworm type lesions were mainly encountered on the exposed areas of the body. M. canis was isolated from the cutaneous lesions of man ana infected pets ; and also directly demonstrated in skin materials. However, the fungus could neither be recovered from the non-contact group nor from the saprobic environment. The isolates from man, dog, and cat showed similar gross as well as microscopic morphology. Further genetic studies so indicated that all the human and animal isolates of M. canis were(-) mating type. It is believed that transmission of zoophilic dermatophytes from animal to man occurs more commonly with direct exposure. In addition, the epidemiology and preventive measures are also discussed.

• Clinical and Experimental Pediatrics
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• v.46 no.10
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• pp.1047-1050
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• 2003

Maternal varicella resulting in viremia may transmit the virus to the fetus by either transplacental spread, or by ascending infection from lesion in the birth canal. The characteristic symptoms consist of skin lesions in dermatomal distribution, eye diseases, neurological defects, and limb hypoplasia. Varicella of the newborn is a life-threatening illness that may occur when a newborn is delivered either within five days of the onset of the illness or after postdelivery exposure to varicella. The severity of neonatal disease is dependent upon the timing of maternal illness. The clinical approach to varicella of newborns should emphasize prevention. Our patient was the first child of a 31-year-old mother who had varicella-zoster ten days before delivery. The child showed muscular hypotonia, poor feeding but no skin lesions.

• 대한상한금궤의학회지
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• v.13 no.1
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• pp.179-188
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• 2021

Objective: This study aimed to report the improvement of a patient with nummular eczema treated by herbal medication based on the Shanghanlun disease pattern identification diagnostic system (DPIDS). Methods: According to the Shanghanlun DPIDS, the patient was diagnosed with Reverting yin disease (provision 351), and was administered Danggwihweyeok-tang for 30 days. The result of administration was evaluated by the Dermatology Life Quality Index (DLQI) and a visual analog scale (VAS). Results: After administration of Danggwihweyeok-tang for 30 days, the DLQI decreased from 18 to 0 and the VAS decreased from 10 to 1. Conclusions: The affected skin region recovered. This case report suggests that the words "厥" and "細" in the 351st Shanghanlun provision refer to physical and internal causes of nummular eczema.