• Journal of IKEEE
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• v.24 no.3
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• pp.713-718
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• 2020

The method of measuring skin active points is a technique for obtaining a lot of biometric information because it is measured with convenience, low cost and non-invasive methods. In this paper, we used in a three electrode measure method that has the advantage of measuring the impedance of the APs under the skin. The impedance measuring method is well illustrated by a simple model of an equivalent electrical circuit that correlates well with experimental results. The characteristic frequencies of APs are about 15-30HZ higher than that of surrounding skin and the values of measured reactance are about 35-77KΩ smaller. This technology analyzed accurately and objectively the reactance and characteristic frequency of APs and the surrounding skin using a non-invasive measuring system.

• Proceedings of the KIEE Conference
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• 2008.10b
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• pp.129-130
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• 2008

교감 신경계의 활성정도를 판별할 수 있는 지표로 피부저항(Galvanic skin resistance: GSR)이 있다. 교감신경이 흥분하면 땀이 분비되어 손가락의 피부저항이 감소하게 된다[1]. 전자기장에 민감한 사람(electromagnetic hypersensitivity: EHS)에게 전자기장을 노출시키면 전자기장을 잘 느끼지 못하는 일반인에 비해 교감신경이 많이 흥분하여 땀을 더 많이 분비할 것이라 생각하여 손가락 피부저항의 변화를 측정하여 전자기장에 민감한 사람과 일반인의 교감신경 활성정도의 차이를 알아보고자 하였다. 그러나 전자기장에 민감한지 민감하지 않은지를 판별하기 위한 인지 및 증상에 관한 설문에 의해서도 피부저항의 변화가 생길 수 있다. 따라서 본 연구에서 전자파에 민감한 사람과 일반인간의 언어자극에 의한 피부저항의 변화를 알아보고 전자기장 노출 실험에서 인지 설문이 전자기장 노출여부에 의한 피부저항의 변화에 영향을 주는지 주지 않는지를 알아보고자 한다. 피부저항 측정 결과 EHS와 일반인군 모두에게서 언어자극(인지 및 자각증상에 관한 설문)에 의해 피부저항이 감소되는 경향을 보였다.

• Proceedings of the Korean Society of Applied Pharmacology
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• 1994.04a
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• pp.276-276
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• 1994

지구 환경문제의 하나인 오존충의 파괴는 지구상에 분포되어있는 자외선량을 증가시키는 외에 지금까지 지상에 도달하지 않았던 단파장역의 자외선량의 증가를 초래하여, 이것에 피부암, 백내장등의 발병율 증가등의 건강 피해가 염려된다. 이들 발병기전은 아직 확실치 않으나 에너지가 큰 단파영역의 자외선에 폭로되면 세포내의 물분자의 이온화에 기인되어 발생하는 활성산소종이 막지질, 핵산. 단백질등에 산화적 손상을 가져와 이것에 돌연변이, 세포사를 초래하는 것이 그 원인의 하나라고 생각된다. 본 연구는 자외선 중 UVB의 조사로 인한 장해와 유도단백질을 찾아내어, 자외선의 유해성을 밝히는데 목적을 두었다. UVB를 농도별로 1회 hairless mouse에게 조사하여, 경시적으로 피부를 채취하여, UVB 조사로 인해 유도되는 단백질을 2차 전기영동법을 이용해 관찰하고. 유도단백질이 HSP인지를 면역염색을 통해 밝히고, 유도된 단백질을 protein sequence를 하여, 어떤 단백질인지 밝혔다.

• Journal of the Korean Institute of Intelligent Systems
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• v.24 no.3
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• pp.316-322
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• 2014

A movie recommendation system is proposed to learn a preference model of a viewer by using multimodal features of a video content and their evoked implicit responses of the viewer in synchronized manner. In this system, facial expression, body posture, and physiological signals are measured to estimate the affective states of the viewer, in accordance with the stimuli consisting of low-level and affective features from video, audio, and text streams. Experimental results show that it is possible to predict arousal response, which is measured by electrodermal activity, of a viewer from auditory and text features in a video stimuli, for estimating interestingness on the video.

• Proceedings of the Korean Society for Emotion and Sensibility Conference
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• 2009.05a
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• pp.149-152
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• 2009

향에 대한 심리생리적 효과는 널리 알려져 있으며 다양한 연구방법을 통하여 보고되고 있다. 본 연구에서는 에센스 제품 향에 대한 심리적, 생리적 반응을 조사하고, 심리적 향 이미지와 생리적 변화간의 변화를 알아보았다. 실험은 피실험자의 EEG, ECG, SKT, GSR을 이용하였다. 실험 결과, 향 종류에 따른 중추신경반응을 뇌파로 측정하여 알파파의 활성을 비교한 결과, Relaxing Fragrance(Neuro $Fragrance^{TM}$) 및 뉴로 에센스, Grapefruit 향 조건에서 알파파의 활성 비율이 높았으며, 좌뇌보다는 우뇌에서 알파파의 활성도가 높았고 Relaxing Fragrance(Neuro $Fragrance^{TM}$)와 뉴고 에센스가 고른 알파파의 활성을 보였다. 향 종류에 따른 자율신경반응을 비교한 결과, 평균 R-R 간격은 Relaxing Fragrance(Neuro $Fragrance^{TM}$)와 뉴로 에센스 조건에서 무향에 비해서 증가하였다. 피부온도와 피부전기저항에서는 무향에 비해서 전체적으로 내려가는 경향을 띄였으며, Relaxing Fragrance(Neuro $Fragrance^{TM}$)와 뉴로 에센스 조건에서 가장 낮았다.

• The Transactions of The Korean Institute of Electrical Engineers
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• v.63 no.9
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• pp.1286-1293
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• 2014

Typically, studies through the simulation system have been progressed, because the evaluation of the driver's arousal state about the service of a actual train has risk of safety for the driver. When configured event same as the real in simulation system, the ability to cope with an accident situation may be the same each other. But the difference in the state of tension or arousal will occur. In this study, requested to cooperate with the railways in order to escape from these constraints, and the target of the experiment was to real engineer service. I was set about experiment when the train was stopped as safe as possible. As a result, the beta wave of EEG signals that representing complex calculations or anxiety is increased rapidly on the basis of a flag station from at the time of departure. The size of the electrodermal activity signal in response to movement of the body gave a noticeable. In terms of HRV, if the train approach a flag station gradually and the R-R interval is narrowed. So that the driver can be estimated as arousal state. In accordance with this study, if the quantitative standard of arousal state be based on the driver's biosignals will provide, it will be able to take advantage of development the system that would prevent train accidents caused by human error.

• Journal of the Society of Cosmetic Scientists of Korea
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• v.41 no.2
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• pp.113-119
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• 2015

The measurement of hydration level in the surface layer of the skin, stratum corneum (SC), gives important information on the biophysical properties and function of the skin barrier such as softness, flexibility, and healthiness of the skin. But it is difficult to measure a consistent hydration level from a sample to another sample due to individual variations and environmental changes. The aim of this study was to evaluate objective hydration after using various products in the SC. The SC Hydration was measured by capacitance (Corneometer$^{(R)}$, C+K, Germany) on the ventral site of forearm from 40 healthy volunteers. The skin surface was chronologically measured immediately after application of the test products and 3 and 6 hours later. We analyzed the averages of five measurements of each site and used the hydration increase rate for correction on untreated site variation. We found that most polyols including glycerol and butylenes glycol influenced directly the hydration increase rate in the SC previously. In this study, glycerol was used to prepare the standard products from 0 to 20 percents and applied to the same volunteers. The individual standard curve showed linear relation to glycerol concentrations. Based on the the standard curve, hydration of SC was converted into hydration increase rate to glycerol concentrations. The converted glycerol concentrations of products were repetitive and reproducible. In addition, the individual standard curve was used to relate the skin type of each individual. These results suggest that the hydration of the SC standardized regardless of external variation and individual skin condition can explain detailed skin state variation. Further studies will be conducted with other ingredients such as surfactants, lipids and aqueous materials, and with other methods for noninvasive measurement.

• Journal of the Society of Cosmetic Scientists of Korea
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• v.23 no.2
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• pp.118-151
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• 1997

Allergic contact dermatitis is a common skin disease resulting from specific immumologic sensitization to topically applied various allergen. Purpose of this study was to investigate skin morphologic chganges by light microscopic, changes of protein band by SDS-PAGE in the skin treated on the surfactant. Furthermore, lectin histochemistry is used to know the chagnges of the terminal sugar of the glycoconjugate in the skin treated on the surfactant. The results were as follows : The 1 day of treated group was indicated the enlargement of capillary, the 3 days of treated group was showed that the cytoplasm was eosinophlic by the pyknotic of nucleus. The 6 days of treated group was observed hyperkeratinoid, increased of inflammation cells to epithelium. The 9 days of treated group was appeares that serum crust was sheded and formed a acanthosis. But dermis layer was cytoplasmic vaculation and enlargement of intercellular space. The 12 days treated group made up new epidermis layer of seven layer and of observed an decreased in quantity of inflammation cells. The mast cell of degranulated type was increased in treated surfactnat. It was secreating granules hold histamin, serotonin and heparin. Accordingly, protein band of electrophortic phase was observed a sudden changes since 3 days treated group. At observeation of the cell-surface glycoconjugates, LCA, PNA, SBA and WGA lectin positive cells but inducated lectin negative cells in Con-A. Furthermore, PNA and SBA showed stroger positive reaction as treated surfactant group.

• Proceedings of the Korean Vacuum Society Conference
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• 2010.02a
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• pp.46-46
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• 2010

최근 상압 저온 플라즈마에서 발생되는 UV와 화학적 활성종들을 이용한 체내 조직 분해 처리, 피부 및 혈관 표면 처리, 대기 및 액체 정화 처리 등의 생체 의료적 응용이 활발하게 연구되고 있다. 이러한 플라즈마에서는 처리 대상 외의 생체 조직의 손상을 최소화 할 수 있는 기술이 필요하며, 이 조건이 확보된 상태에서 처리 목표 대상에 따른 플라즈마 특성, 즉 선택적 생성종 제어와 플라즈마 온도를 안정적으로 관리할 수 있어야 한다. 인체 내부 조직에 대하여 유효 활성종 등의 직접적인 작용이 필요할 경우 밀리미터 크기 이하의 미세침습성 플라즈마를 활용하게 된다. 이 경우 방전 특성을 간접적으로만 관측 가능하여 주변 조직과 플라즈마 간의 상호 영향 등이 고려되어야 하므로 직접적인 관측이 가능한 인체 외부에서 발생된 플라즈마에 비해서 더욱 정교한 제어가 필요하다. 본 연구에서는 미세 침습성 플라즈마의 발생 메커니즘 및 특성 분석을 수행하여 척추 디스크 탈출 치료 시술에 활용하기 위한 연구를 수행하였다. 처리 대상 조직으로의 접근 시 주변 조직의 손상을 막기 위하여 수 밀리미터 이하의 미세한 전극을 이용하였으며 전기 전도성을 띄는 인체 내부에서 절연공간의 확보를 위해 전극 표면에서 기포를 발생시켜 플라즈마 방전이 가능한 조건을 확보하였다. 또한 플라즈마 방전이 중단되거나 혹은 갑작스런 열 플라즈마로의 천이로 인해 생체에 심각한 열 손상을 초래하는 현상을 방지하기 위하여 발생 플라즈마와 주변 디스크간의 상호 영향을 통한 플라즈마의 동적인 특성 변화 및 안정적인 플라즈마 발생을 위한 조건을 도출하였다. 이를 실제 임상 실험에 활용한 결과를 소개하고 아울러 차세대 의료용 플라즈마 발생 장치 개발을 위한 플라즈마 학계의 관심을 이끌어 보고자 한다.

• Journal of the Korean Society of Fashion and Beauty
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• v.2 no.2 s.2
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• pp.101-106
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• 2004

Allergic contact dermatitis is a common skin disease resulting from specific immunologic sensitization to topically applied various allergen. The Purpose of this study was to investigate skin morphologic cahnges by light microscopic and scanning electron Microscope, changes of protein band by SDS-PAGE(SDS-polyacrylamide gel electrophoresis) in the skin effectiveness for beruty improvement of Geranium essential oil on skin troubles by surfactant. The results of the study are as follows, 1. From the observed result of FE-Scanning Electron Microscope, groups treated by Geranium essential oil in group treated Geranium essential oil during 1 week in surfactant treated group during 1 week, the group was repaired in irregularity surface of tissue by alleviate-keratinization of Geranium essential oil. 2. As a result of protein analysis the group treated on surfactant was rised protein upper range of 97,0004a11on by hyper-keratinization and group treated during 1 week by surfactant was decreased protein below range of 43,000dalton.