• 월간산업보건
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• s.385
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• pp.9-13
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• 2020

삼염화인(Phosphorus trichloride)의 노출기준은 눈, 피부, 점막 그리고 호흡기계 기관지 자극의 가능성을 최소화하기 위해 TLV-TWA는 0.2ppm(1.1 mg/㎥), TLV-STEL은 0.5ppm(2.8 mg/㎥)으로 권고하였다. 삼염화인은 직접 피부 접촉 시 심각한 화상을 유발할 수 있으며 공기 중 농도 2ppm~27ppm 범위에서 작업자가 급성 노출되면 인두, 기침, 호흡 곤란 및 심한 천식 기관지염을 유발하는 것으로 보고되었다. 물 또는 습한 공기에서 삼염화인은 염산 및 인산으로 분해된다.(ACGIH의 인산 TLV 문서를 참조하는 것이 필요함). 피부흡수(Skin), 감작제(SEN)의 경고주석과 발암성을 표기하기에는 유용한 자료가 충분하지 않다.

• Proceedings of the Korean Society of Fisheries Technology Conference
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• 2000.10a
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• pp.187-188
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• 2000

최근 자외선 차단제의 사용이 증가하면서 자외선 차단제 도포로 인한 자극성 피부염, 접촉 피부염, 광알레르기성 또는 광독성 피부염 등의 보고가 증가하고 있어 피부에 자극이나 알레르기 반응, 독성을 나타내지 않는 적절한 천연소재 자외선 차단제의 개발에 대한 필요성이 증대되고 있다. 이에 본 연구에서는 새로운 자외선 차단제 개발을 위한 기초 자료를 확보하기 위하여, 국내산 해조류 중의 자외선 흡수 물질의 분포를 조사하였다. (중략)

• Journal of the Institute of Convergence Signal Processing
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• v.24 no.3
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• pp.153-159
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• 2023

As research results showed that ozonated olive oil has excellent therapeutic effects on skin diseases, attempts were made to develop cosmetics manufacturing technology using ozone. Ozone is harmful to the human body, so a separate facility must be prepared to manufacture ozonated olive oil as a cosmetic raw material. The manufacturing device developed in this study was designed as an optimized process for manufacturing cosmetics while ensuring the safety of workers involved in production. To verify the ozonated olive oil produced from the implemented device, a toxicity test was conducted on animals. After applying ozonated oil (high concentration) to the rabbit's back for 24 hours, mortality, general symptoms and symptoms were measured. A skin irritation evaluation was performed. As a result of the experiment, as a result of evaluating the test substance treatment area after a certain period of time, it was confirmed that no skin irritation was observed in all animals, confirming the safety of the ozonated oil production process and the safety of the product.

• Journal of Biomedical Engineering Research
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• v.19 no.5
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• pp.539-546
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• 1998

The purpose of this study is to estimate human emotion quantitatively under colors and music stimuli and to examine the for correlation between color and music sensibility. Physiological signals(electroencephalogram, electrocardiogram, Galvanic skin conductivity and respiration rate) were measured to compare color with music sensibilities. The personality of the subject were investigated using factor analysis and semantic differential method of 20 items(7 interval scaled). The results showed that red, yellow and violets color provoked active and exciting senses mainly as dance, rock and blues music. While blue, cyan and pink colors ware involved in tranquil and resting emotions deeply as classic and ballade music.

• Proceedings of the Korea Information Processing Society Conference
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• 2013.11a
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• pp.1474-1475
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• 2013

부항은 열 또는 음압(陰壓)장치에 의하여 부항단지 안에 음압을 조성하여 피부에 붙임으로써 피를 뽑거나 울혈(鬱血)을 일으키며 물리적 자극을 주어 병을 치료한다. 부항으로 얻어지는 물리적인 자극은 혈액순환을 촉진하고, 죽은피를 빼냄으로써 혈관을 자극하고 그로인해 다양한 효과를 얻는다. 따라서 본 논문에서는 신장에 해당하는 명문혈을 자극하여 신장과 관련된 음성분석 요소의 변화를 측정하였다. 이를 위해 신장에 이상이 없는 피실험자 10명을 선정하고 신장에 해당하는 명문혈을 자극하기 전과 후의 음성을 수집하였다. 실험은 음성분석 요소 중 신장과 관련된 1 Formant Bandwidth를 적용하여 신장 명문혈 자극 전과 후의 변화를 측정, 분석하였다. 실험 결과, 90%의 피실험자가 값이 감소하는 현상을 보였으며, 이를 통해 명문혈 자극에 따른 신장과 음성신호와의 상관성을 분석할 수 있었다.

• Journal of Veterinary Clinics
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• v.28 no.6
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• pp.607-609
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• 2011

A 6-year-old, neutered female, Cocker spaniel presented with severe abdominal erythema and crusts. These conditions developed 1 month ago. This patient had a history of using humectant spray for several months. Irritant contact dermatitis was diagnosed by history, clinical signs, laboratory and histopathologic examinations (H-E stain). Complete blood count and serum chemistry showed no remarkable findings. Histopathologic examination of skin samples revealed parakeratosis accompanied by acanthosis of the dermis and mild perivascular inflammations of the superficial dermis. Clinical signs were improved after avoidance of suspected offending substance.

• Journal of the Society of Cosmetic Scientists of Korea
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• v.22 no.1
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• pp.70-83
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• 1996

자외선 차단제는 화장품 원료 중 주요 자극원의 하나이다. 그러나 자오선 차단제를 고분자로 만들 경우 피부에 도포 되었을 때 경피흡수가 불가능 하여 피부 자극 문제를 해결할 수 있다. 이에 본 연구에서는 PVBC와 alkylhydroxycinnamate를 반응시켜 고분자 자외선 차단제를 합성하였다, PVBC는 benzylic chloride를 가지고 있는 고분자로서 이 작용기는 친핵성 치환반응이 용이하므로 side chain modification이 가능하다. PVBC와 alkyl hydroxycinnamate의 반응에서 반응성은 alkyl hydroxycinnamate의 크기와 반응에 첨가된 촉매의 종류에 영향을 받는다. 효율이 낮은 촉매를 사용할 경우에는 alkyl hydroxycinnamate의 크기가 작을수록 반응수율이 높았으며, 높은 효율을 갖는 촉매를 사용할 경우에는 alkyl hydroxycinnamate의 종류에 관계없이 반응수율은 100%였다. 실험에 사용한 PVBC는 평균 분자량이 55,000이었으며, 고분자의 구조와 분자량은 NMR과 GPC로 확인하였다. 고분자 자외선 차단제의 자외선 흡수 능력은 OMC에 비해 65 - 94% 였으며, caprylic/capric triglyceride에 좋은 용해도를 보여주었다.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.12 no.5
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• pp.2434-2438
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• 2011

Ghana is the country that produces world's biggest production of Cacao. Cacao is the main ingredient of chocolate, which has been widely used in a variety of food as its anti-oxidantal effect is well known to public. Moreover, Ghana-produced Cacao is known to have a bigger amount of polyphenol compared to the ones produced elsewhere, and as they are not processed with alkali Ghana-produced Cacoa is slightly acidic as it is. This project aimed at analysing this natural Ghana Cacao's polyphenol composition, developed cosmetic mask using it and don skin irritation tests in order to study skin improvement effect. As a result, it was found that Ghana-produced Cacao contains approximately 3.6% of tannin, showing 5.6 pH. From the result of the first skin irritation test, the result of experiment of the cometic masks which contain 15% of Ghana cacao powder showed that the irritation was not shown. After 120 minutes, in the experiment of skin improvement effect, it was proved to have skin improvement effect, appearing 20% increase in skin moisture, -17% decrease in skin moisture evaporation, convergence of 5.3pH, 24% increase in skin elasticity.

• Journal of Digital Convergence
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• v.12 no.4
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• pp.419-425
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• 2014

The objective of this study is to estimate the inhibition of skin melanin formation by extract of Angelica koreana and Cnidium monnieri and the possibility of functional cosmetic materials through anti-irritation and stability test. The extract used in this experiment is White-$AK^{TM}$ and the INCI name is Osthole. The main component of White-$AK^{TM}$ was identified as coumarin and EC50 value was 2.7ppm by mouse melanoma B 16 cell test. White-$AK^{TM}$ showed inhibitory effects 100 times lower concentration than arbutin. The main mechanism for skin whitening effect thought to be inhibition of tyrosinase-related gene expression. The basic essence formulation of White-$AK^{TM}$ 5% solution applied to the skin showed the effect of relieving skin irritation. White-$AK^{TM}$ in an opaque container, under UV conditions for 4 weeks, and showed close to 100% recovery and 97% recovery under $50^{\circ}C$ for 4 weeks. Therefore, it is thought that White-$AK^{TM}$ which helps skin whitening, relieving skin irritation and stable in UV condition is able to be used as the functional component in the cosmetic formulation.

• The Korean Journal of Pesticide Science
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• v.17 no.4
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• pp.478-481
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• 2013

This study was performed to evaluate the acute skin and eye irritation of plant extracts (neem and sophora) against rabbit. The result of skin irritation test indicated that neem extracts and sophora extracts were not irritant. For eye irritation test, the result showed no irritation for neem extracts. Sophora extracts have a severe eye irritation and the symptoms have been reduced to day 3. Thus, safety guidelines for agricultural workers is considered to be needed when sophora extracts is used as an organic agricultural materials.