• Journal of The Korean Society of Inherited Metabolic disease
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• v.15 no.2
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• pp.98-100
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• 2015

Short-chain acyl-CoA dehydrogenase (SCAD) deficiency is a rare mitochondrial fatty-acid oxidation disorder that is inherited as an autosomal recessive pattern. SCAD deficiency is caused by mutations in the ACADS gene (Acyl-CoA Dehydrogenase, Short-chain, OMIM #606885), which encodes SCAD, the mitochondrial enzyme that catalyzes the first reaction in the beta-oxidation of fatty acids four to six carbons in length. Here, we describe one Korean pediatric case of SCAD deficiency, which was diagnosed during newborn screening through tandem mass spectrometry. An increased concentration of butyrylcarnitine was detected on the newborn screening test, and the urine organic acid analysis showed increased urinary excretion of ethylmalonic acid. The patient has been asymptomatic and has shown normal growth and development by 8 months of age without any intervention during follow-up period.

• Proceedings of the Korea Society for Energy Engineering kosee Conference
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• 2007.11a
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• pp.193-198
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• 2007

KIER has been developing the anode supported flat tubular SOFC stack for the intermediate temperature $(700{\sim}800^{\circ}C)$ operation. for this purpose, we have first fabricated anode supported flat tubular cells by the optimization between the current collecting method and the induction brazing process. After that we designed the compact fuel & air manifold by adopting the simulation technique to uniformly supply fuel & air gas and the unique seal & insulation method to make the more compact stack. For making stack, the prepared anode-supported flat tubular cells with effective electrode area of $90cm^2$ of connected in series with 12 modules, in which one module consists of two cells connected in parallel. The performance of stack in 3 % humidified $H_2$ and air at $800^{\circ}C$ shows maximum power of 507 W. Through these experiments, we obtained basic & advanced technology of the anode-supported flat tubular cell and established the proprietary concept of the anode-supported flat tubular SOFC stack in KIER.

• Tunnel and Underground Space
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• v.21 no.3
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• pp.235-243
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• 2011

In this study, a control blast method, which utilizes crack guide holes, is suggested to achieve smooth fracture plane and minimize blast damage zone (BDZ) in smooth blasting. In order to verify the effectiveness of crack guide holes on the fracture plane control in blasting, fracture process analyses which consider regular smooth blasting and guide hole smooth blasting had been conducted and the fracture planes resulting from the analyses had been compared. The analyses models considered the ignition of the blast holes using detonation cords and each guide hole placed between blast holes. From the results, the smooth blasting utilizing guide holes showed lower fracture plane roughness than regular smooth blasting method in the hole spacing range between 20 to 40cm.

• The Journal of Internal Korean Medicine
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• v.40 no.6
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• pp.1051-1062
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• 2019

Objectives: Chest pain presents diagnostic and therapeutic challenges because of its various etiologies. Many patients have chest pain from unknown causes and persistent chest pain in spite of standard treatment. The purpose of this study was to investigate the effectiveness of a Korean herbal medicine called Pyungjinsujeom-san (PSS) in relieving chest pain. Methods: We reviewed the electronic medical records of patients who visited the Korean Medical Clinic of Cardiology at Kyunghee University Hospital at Gangdong from January 2009 to July 2019, with the chief complaint of chest pain and who were treated with PSS. The mean severity of chest pain measured on the Numerical Rating Scale was compared before and after the administration of PSS. Results: The mean severity of chest pain of 20 patients decreased significantly from 6.80±1.61 to 1.35±0.9 after taking PSS (p<0.001). Most patients had symptoms of phlegm and food retention, including indigestion, postprandial fullness, and epigastric pain.Conclusions: These results suggest that PSS may be effective in relieving chest pain from various causes, particularly in patients with symptoms of phlegm and food retention.

• Proceedings of the Korea Technical Association of the Pulp and Paper Industry Conference
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• 2000.11a
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• pp.63-63
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• 2000

저급의 고지 원료를 두께 방향으로 고온 압착을 가하여 건조함으로써 전반적인 종이 물성 을 향상시키는 콘디벨트 건조 방식은 70년대 중반부터 80년대에 이르는 10여년에 걸친 개발 과정을 거쳤으며 90년대에 들어서 핀랜드의 Inkeroinen에 위치한 V alemt- Tarnpella의 연구 소에 최초의 파일로트 설비가 설치되었으며 그 후 1996년에는 핀랜드 ENSO사의 P Pank밟oski 판지공장에 설치됨으로써 세계 최초의 상업생산설비를 이루게 되었다. 기존의 실린더 건조 기술과 비교할 때 콘디벨트 건조방식은 건조속도를 약 5-15배 향상시킬 수 있 으며, 건조 에너지 절감에 큰 효과가 있을 뿐만 아니라 기존의 실린더 건조시 종이가 폭방 향으로 수축되 어 인장 stiffness와 압축 강도 동의 종이 물성 이 저 하되 는 반면 습윤상태 의 섬유를 120도씨이상에서 가열에 의해 리그닌을 연화시킴과 동시에 섬유의 유연성을 증가시켜 준다. 그리고 높은 압력을 가해줌으로써 섬유간의 결합 면적을 증가시키고 건조시 종이의 폭방향의 수축을 감소시켜 인장강도, 내부결합강도, 밀도, 표면평활성, 투기저항성 등 종이의 물성을 대폭 향상시켜주는 혁신적인 제지기술로 인정받고 있으며 국내의 경우 현재 1998년 부터 상업생산을 이루어짐으로써 그 공헌도는 매우 크다고 할 수 있다. 골판지의 주원료가 되는 국산 골판지 고지 (Korean old corrugated container, K KOCC)의 거듭된 재생처리로 인하여 미세분의 함량이 전체 지료의 절반 이상에 달할 뿐만 아니라, 섬유가 각질화와 단섬유화로 인하여 고온압착 건조처리 만으로는 골판지 고지로 생 산된 원지의 강도를 버진펄프로 생산된 원지가 가지는 강도에 준하는 강도로 향상시키는데 한계점을 가지게 된다. 유럽의 제지선진국들은 골판지 원지의 강도를 향상시키는 방편으로 표변에 전분 사이즈 프레스 처리를 도입하였으며 본 연구에서는 고온 압착 건조 처리 설비를 활용한 전분 표면처리의 가능성을 검토하고 골판지 원지의 강도를 향상시키기 위한 표면처리조건을 탐색하였다.

• Fire Science and Engineering
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• v.18 no.3
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• pp.74-94
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• 2004

Fire trends in Korea, Japan, and the United States were analyzed in this paper. The number of fires in the U.S. tends to decrease greatly from 3,264,500 cases in 1977 to 1,687,500 in 2002. There have been an estimated 60,000 fires annually more than 20 years in Japan, at the peak of 73,072 cases in 1973. In case of Korea, 5438 fires occurred in 1980. However, fires increased rapidly up to 36,169 cases in 2001 and 31,372 cases in 2003. In addition, fire statistics processing methods and fire statistics reports were analyzed. The result was that Korea was behind most of the three countries. Therefore I confirmed that we need not only to study systematical processing methods of fire statistics in order to get confidence on those like accurate estimating fire data analysis, but also to publish variable and specific reports on fires for the purpose of analyzing fire data.

• The Journal of The Korea Institute of Intelligent Transport Systems
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• v.11 no.3
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• pp.92-101
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• 2012

Trip demands and patterns on weekends have been changed significantly over the past decade due to the income growth and the spread of the 5-day workweek in Korea. The increased weekend trips for shopping, leisure activities, entertainment and friendship have exacerbated traffic congestion in major highways or principal arterial roads from Friday afternoon through Sunday. Therefore, it is necessary to focus on travel demand forecasts and transport policies for weekend trips by investigating specific characteristics of the trips. Previous research efforts focus on simple analysis of characteristics of weekend trips and comparison of travel characteristics between weekdays and weekends. The paper analyzes the differences between weekday and weekend trips via statistical analyses to derive multiple types of characteristics of weekend trips, and develops Tobit models to identify key factors that may affect the number of trips, using Seoul city's weekend trip survey data in 2006. The model results show that weekend trips appear differently from weekdays by household or individual characteristics. Age, residence area and type of residence affected the number of trips, regardless of the type of the day, whereas gender, occupation, income, presence of household vehicle showed different impacts on trips between weekdays and weekends.

• Journal of the Korean housing association
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• v.22 no.4
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• pp.43-50
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• 2011

In an aging society, as the number of people with disabilities increases concerns are raised about the quality of life of these people and their access to a safe environment becomes important. The purpose of this study is to find out the value of accessibility as an attribute of housing. To estimate the value of accessible, barrier-free housing, this study uses the Contingent Valuation Method (CVM) and analyzes the factors which affect the Willingness To Pay (WTP) of survey respondents by using Survival Analysis. In addition, the importance and satisfaction of barrier-free facilities in the dwellings of survey respondents was investigated. Since aging could be an important factor in influencing the need for accessibility, this study surveyed two age groups, one group (212 respondents) of people below the age of 65 and the other (162 respondents) of people above 65. The results of this study show that respondents would pay on average 2.67% more for being barrier-free when answering an open-ended question and 3.87% more for barrier-free housing when using the double referendum model. This is the increase in value that the respondents perceive as a consequence of removing all the architectural barriers from a dwelling. On average, elderly respondents would pay 2.99% of housing price for accessible features compared to 4.40% of the younger group. However, if the elderly who have willingness to pay for accessibility, the value the older group put on barrier-free housing was higher than the value perceived by the younger group. Factors that influence the WTP are importance of barrier-free facilities, education level and housing type. The value of dwellings without barriers estimated in this study shows the potential size and value of this kind of housing market to the housing development sector.

• Journal of Periodontal and Implant Science
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• v.26 no.1
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• pp.317-333
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• 1996

The main goal of periodontal regeneration is to be achieved by epithelial exclusion, periodontal ligament cell activation or alveolar bone regeneration. The purpose of this study was to investigate on the physico- chemical and biological characteristics of biodegradable chitosan beads. Chitosan beads were fabricated by ionic gelation with sodium tripolyphosphate and they had the size in 300um diameter. As therapeutic agent, flurbiprofen was incorporated into the beads by 10, 20% loading contents. The release of drugs from the chitosan beads was measured in vitro. Also, biological activity tests of flurbiprofen loaded chitosan beads including cytotoxicity test, ihhibition of $IL-1{\beta}$ production, suppression to $PGE_2$ production, collagenase inhibition test, the ability of total protein synthesis, and tissue response were evaluated. The amount of flurbiprofen released from chitosan was 33-50% during 7 days. Minimal cytotoxicity was observed in chitosan beads. Flurbiprofen released from chitosan beads significantly suppressed the $IL-1{\beta}$ production of monocyte, $PGE_2$ production and markedly inhibited collagenase activity. Meanwhile, flurbiprofen released from this system showed increased ability for protein synthesis. Throughout 4 -week implantation period, no significant inflammatory cell infiltrated around chitosan bead and also fibroblast like cell types at the beads - tissue interface were revealed with gradual degradation of implanted chitosan beads. From these results, it was suggested that flurbiprofen loaded chitosan beads can be effectively useful for biocompatible local delivery system in periodontal regeneration.

• Journal of the Korean Society of Safety
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• v.30 no.6
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• pp.40-47
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• 2015

In this study, temperature characteristics and fire damage form were analyzed to investigate flame spreading form and fire probability from ignition sources subject to drivit component materials which is finishing material in architecture. Ignition sources were limited to a gas torch and exterior panel board fire, and the size of the sample was manufacture in 30 cm length ${\times}$ 50 cm height ${\times}$ 5cm thickness size. Marble (inner wall) + 3 mm drivit (outer wall), marble (inner wall) + 4 mm plaster stone (outer wall), sandwich panel + 3 mm driver bit (outer wall), sandwich panel + 3 mm driver bit + insulation (outer wall), and gypsum board (inner wall) + 3 mm drivit (outer wall) were prepared for the sample. As result of the research for temperature characteristics, large temperature difference by each material was shown in $218^{\circ}C{\sim}995^{\circ}C$ at 30 seconds and $501^{\circ}C{\sim}1078^{\circ}C$ at 300 seconds. Especially when the inner wall was a plaster board, lowest temperature of $501^{\circ}C$ was shown at 300 seconds and marble inner wall showed the following lowest temperature of $900^{\circ}C$. Temperature rising over $1000^{\circ}C$ was shown in other materials. Regarding fire damage form, drivit or gypsum board outer wall parts exposed to fire showed combustion and carbonization to show calcination(breaking phenomenon) and influence of heat exposure was higher as calcination became more severe.