• Food Science and Preservation
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• v.24 no.6
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• pp.795-801
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• 2017

Aralia elata Seemann (AE) has long been used as a folk medicine for the treatment of various diseases including diabetes mellitus, anti-arthritic, and anti-gastric ulcer agent in Korea, Japan, and China. This study was performed to establish a simple and reliable HPLC/UV analytical method for determination of most active anti-hypertensive compound, a 3-O-${\alpha}$-L-rhamnopyranosyl($1{\rightarrow}$2)-${\alpha}$-L-arabinopyranosyl hederagenin 28-O-${\beta}$-D-xylopyranosyl($1{\rightarrow}6$)-${\beta}$-D-glucopyranosylester (HE) for the standardization of the shoot extract of AE as a health functional food ingredient. The quantitative analytical method of HE was optimized by HPLC analysis using reverse-phase C18 column at $40^{\circ}C$ with $H_2O$ and acetonitrile (70:30, v/v) as an isocratic mobile phase at a flow rate of 1.0 mL/min and detection wavelength of UV 205 nm. This HPLC/UV analytical method showed good specificity and high linearity in the tested range of 0.03125-2.0mg/ml with excellent coefficient of determination ($R^2$) of 0.9999. The limit of detection and limit of quantification were $12.0{\mu}g/mL$ and $36.5{\mu}g/mL$, respectively. Relative standard deviation (RSD) values of data from intra- and inter-day precision were less than 0.2% and 0.1%, respectively. These results indicate that the established HPLC/UV analytical method is very simple, specific, precise, accurate, and reproducible and thus can be useful for the quantitative analysis of HE as a functional anti-hypertensive compound in AE extract.

• Clinics in Shoulder and Elbow
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• v.10 no.2
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• pp.160-166
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• 2007

Purpose: The current study assessed the factors affecting outcomes of primary repair procedures in tears of multiple rotator cuff tendons. Materials and Methods: Among the cases of rotator cuff tears involving two or more tendons receiving operations between 1997 and 2003, The clinical results of 19 cases with more than 2 years follow-up were evaluated by the UCLA score. We evaluated the correlation of trauma, active motion, acromiohumeral distance, tear size, and surface area with the UCLA score using Pearson's linear correlation coefficient (PLCC). Results: UCLA scores increased significantly in all cases, from 9 to 26.1 on average. However, the results were good in 53%, and poor in 47% according to Ellman's criteria. Trauma, active elevation, acromiohumeral distance, and tear size did not correlate with the UCLA score, but the tear surface area was inversely correlated with the score (PLCC=-0.696). Cases with degeneration of the infraspinatus muscle above Goutallier grade III on MRI showed worse results than cases with less degeneration. Conclusion: The clinical results of primary repair of rotator cuff tears involving multiple tendons were satisfactory in 53% of patients. Large tear surface area and severe degeneration of the infraspinatus were poor prognostic factors.

• The Journal of the Korea Contents Association
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• v.18 no.12
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• pp.150-160
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• 2018

Purpose: This study was conducted to understand what various factors influence school life adaption of nursing students by measuring life stress, anger and optimism. Methods: The subjects were 186 students in B city and the data were collected for the period of 17-28 April 2017. The collected data were analyzed with an independent t-test, ANOVA, Scheffe's method, Cronbach's alpha and Pearson's correlation coefficients. The results are as follows respectively: life stress 1.34/4, state anger 1.24/4, trait anger 1.57/4 at average, and among optimism was 3.45/5 at average. Multiple regression analysis showed perceived physical health status(${\beta}=.20$ t=2.72, p=.007), satisfaction on college(${\beta}=.19$, t=2.53 p=.012) and life stress (${\beta}=-.14$ t=-2.28, p=.027) were related to factors. They accounted 18.2% of the optimism of the subjects. However, there was no significant correlation between optimism and anger of nursing students. Conclusion: It is necessary to develop a program to improve the optimism of nursing college students and to develop a program that can enhance the coping ability of stress to cope with life stress experienced by nursing students.

• Proceedings of the Korea Water Resources Association Conference
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• 2021.06a
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• pp.444-444
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• 2021

하천의 오염부하량 관리 계획은 지속적인 모니터링을 통한 자료 구축과 모형을 이용한 예측결과를 기반으로 수립된다. 하천의 모니터링과 예측 분석은 많은 예산과 인력 등이 필요하나, 정부의 담당 공무원 수는 극히 부족한 상황이 일반적이다. 이에 정부는 전문가에게 관련 용역을 의뢰하지만, 한국과 같이 지형이 복잡한 지역에서의 오염부하량 배출 특성은 각각 다르게 나타나기 때문에 많은 예산 소모가 발생 된다. 이를 개선하고자, 본 연구는 합성곱 신경망 (convolution neural network)과 수문학적 이미지 (hydrological image)를 이용하여 강우 발생시 BOD 및 총인의 부하량 예측 모형을 개발하였다. 합성곱 신경망의 입력자료는 일반적으로 RGB (red, green, bule) 사진을 이용하는데, 이를 그래도 오염부하량 예측에 활용하는 것은 경험적 모형의 전제(독립변수와 종속변수의 관계)를 무너뜨리는 결과를 초래할 수 있다. 이에, 본 연구에서는 오염부하량이 수문학적 조건과 토지이용 등의 변수에 의해 결정된다는 인과관계를 만족시키고자 수문학적 속성이 내재된 수문학적 이미지를 합성곱 신경망의 훈련자료로 사용하였다. 수문학적 이미지는 임의의 유역에 대해 2차원 공간에서 무차원의 수문학적 속성을 갖는 grid의 집합으로 정의되는데, 여기서 각 grid의 수문학적 속성은 SCS 토양보존국(soil conservation service, SCS)에서 발표한 수문학적 토양피복형수 (curve number, CN)를 이용하여 산출한다. 합성곱 신경망의 구조는 2개의 Convolution Layer와 1개의 Pulling Layer가 5회 반복하는 구조로 설정하고, 1개의 Flatten Layer, 3개의 Dense Layer, 1개의 Batch Normalization Layer를 배열하고, 마지막으로 1개의 Dense Layer가 연결되는 구조로 설계하였다. 이와 함께, 각 층의 활성화 함수는 정규화 선형함수 (ReLu)로, 마지막 Dense Layer의 활성화 함수는 연속변수가 도출될 수 있도록 회귀모형에서 자주 사용되는 Linear 함수로 설정하였다. 연구의 대상지역은 경기도 가평군 조종천 유역으로 선정하였고, 연구기간은 2010년 1월 1일부터 2019년 12월 31일까지로, 2010년부터 2016년까지의 자료는 모형의 학습에, 2017년부터 2019년까지의 자료는 모형의 성능평가에 활용하였다. 모형의 예측 성능은 모형효율계수 (NSE), 평균제곱근오차(RMSE) 및 평균절대백분율오차(MAPE)를 이용하여 평가하였다. 그 결과, BOD 부하량에 대한 NSE는 0.9, RMSE는 1031.1 kg/day, MAPE는 11.5%로 나타났으며, 총인 부하량에 대한 NSE는 0.9, RMSE는 53.6 kg/day, MAPE는 17.9%로 나타나 본 연구의 모형은 우수(good)한 것으로 판단하였다. 이에, 본 연구의 모형은 일반 ANN 모형을 이용한 선행연구와는 달리 2차원 공간정보를 반영하여 오염부하량 모의가 가능했으며, 제한적인 입력자료를 이용하여 간편한 모델링이 가능하다는 장점을 나타냈다. 이를 통해 정부의 물관리 정책을 위한 의사결정 및 부족한 물관리 분야의 행정력에 도움이 될 것으로 생각된다.

• The Journal of the Convergence on Culture Technology
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• v.9 no.3
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• pp.271-279
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• 2023

The purpose of this study was to investigate the effect of learning flow, problem solving ability, professor-student interaction of academic achievement in nursing students. Data were collected from 274 nursing students in B city and analyzed by t-test, ANOVA, Pearson correlation coefficient, and hierarchial multiple regression using SPSS/WIN 22.0. The degree of academic achievement in nursing students was 3.70±0.70. There were significant differences in academic achievement with grade(F=4.755, p=.003), campus life satisfaction(F=5.643, p=.004), major satisfaction(t=5.794, p=.003), adapting to COVID-19(F=7.961, p<.001), satisfaction to non-face-to-face environment class(F=18.353, p<.001). There was positive correlation between academic achievement and learning flow(r=.649, p<.001), problem solving ability(r=.333, p<.001), professor-student interaction(r=.479, p<.001). The factors affecting academic achievement of the study subjects were learning flow(β=.563, p<.001), professor-student interaction(β=.280, p<.001), with an explanatory power of 52.0%. Therefore, strategies increase the academic achievement of nursing students in untact lecture, and environment improvement to increase learning flow and professor-student interaction are needed.

• The Journal of Engineering Geology
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• v.33 no.4
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• pp.599-609
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• 2023

In the seismic retrofitting of harbor breakwaters in Korea, the recovery rate is often uncertain due to site conditions and site conditions, and problems continue to arise. Therefore, in this study, we analyzed the recovery rate and compressive strength of the improved material through drilling survey by grouting confirmation method after applying low-fluidity mortar injection method, and furthermore, we checked the elastic modulus by downhole test and tomography to confirm the reinforcement effect of soft ground after ground improvement. The experimental results showed that the average shear wave velocity of the ground increased from 229 m/s to 288 m/s in BH-1 and BH-3 boreholes to a depth of 28.0 m, and the average shear wave velocity of the ground to a depth of 30.0 m tended to increase from 224 m/s to 282 m/s in the downhole test. This is believed to be a result of the increased stiffness of the ground after reinforcement. The results of the tomographic survey showed that the Vs of the soft ground of the sample at Site 1 increased from 113 m/s to 214 m/s, and the Vs of the sample at Site 2 increased from 120 m/s to 224 m/s. This shows that the stiffness of the ground after seismic reinforcement is reinforced with hard soil, as the Vs value satisfies 180 m/s to 360 m/s in the classification of rock quality according to shear wave velocity.

• Food Science and Preservation
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• v.19 no.1
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• pp.95-103
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• 2012

The objective of this study was to develop models for the predict of the milk properties (fat, protein, SNF, lactose, MUN) of unhomogenized milk using the visible and near-infrared (NIR) spectroscopic technique. A total of 180 milk samples were collected from dairy farms. To determine optimal measurement temperature, the temperatures of the milk samples were kept at three levels ($5^{\circ}C$, $20^{\circ}C$, and $40^{\circ}C$). A spectrophotometer was used to measure the reflectance spectra of the milk samples. Multilinear-regression (MLR) models with stepwise method were developed for the selection of the optimal wavelength. The preprocessing methods were used to minimize the spectroscopic noise, and the partial-least-square (PLS) models were developed to prediction of the milk properties of the unhomogenized milk. The PLS results showed that there was a good correlation between the predicted and measured milk properties of the samples at $40^{\circ}C$ and at 400~2,500 nm. The optimal-wavelength range of fat and protein were 1,600~1,800 nm, and normalization improved the prediction performance. The SNF and lactose were optimized at 1,600~1,900 nm, and the MUN at 600~800 nm. The best preprocessing method for SNF, lactose, and MUN turned out to be smoothing, MSC, and second derivative. The Correlation coefficients between the predicted and measured fat, protein, SNF, lactose, and MUN were 0.98, 0.90, 0.82, 0.75, and 0.61, respectively. The study results indicate that the models can be used to assess milk quality.

• Journal of Chest Surgery
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• v.35 no.10
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• pp.705-711
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• 2002

The advantages of mitral valve reconstruction have been well established and so mitral valve reconstruction is now considered as the procedure of choice to correct mitral valve disease. This is the report of intermediate-term results of 38 cases that performed mitral valve reconstruction for valve insufficiency(the total number of mitral valve reconstruction were 49 cases, but 11 cases that performed mitral valve replacement due to incomplete reconstruction were excluded). Material and Method : From March 1991 to March 2001, 38 patients underwent mitral valve repair due to mitral valve regurgitation with or without stenosis. Mean age was 47.6$\pm$14.7 years(range 15 to 70 years) : 11 were men and 27 were women. The causes of mitral valve regurgitation were degenerative in 14, rheumatic in 21, infective in 2 and the other was congenital. Result : According to the Carpentier's pathologic classification of mitral valve regurgitation, 3 were type 1 , 16 were type II and 19 were type III. Surgical procedures were annuloplasty 15, commissurotomy 19, leaflet resection and annular plication 9, chordae shortening 11, chordae transfer 5, new chordae formation 2, papillary muscle splitting 2 and vegetectomy 2. These procedures were combined in most patients. There were 2 early death and the causes of death were respiratory failure, renal failure and sepsis. There was no late death. Valve replacement was done in 6 patients after repair due to valve insufficiency or stenosis 3 weeks, 1, 3, 51, 69, 84months later respectively. These patients have been followed up from 1 to 116 months(mean 43.0 months). The mean functional class(NYHA) was 2.36 pre-operatively and improved to 1.70. Conclusion : In most cases of mitral valve regurgitation, mitral valve reconstruction when technically feasible is effective operation that can achieve stable functional results and low surgical and late mortality.

• Journal of Chest Surgery
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• v.35 no.3
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• pp.177-181
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• 2002

Background: Follow-up studies have shown that although outcomes have improved substantially over time, results of the Fontan operation and its modifications remain suboptimal. In this study, we reviewed our experience with the extracardiac conduit Fontan operation, with a focus early and midterm change of internal diameter of PTFE conduit. Material and Method: Between April 1997 and July 2000 were reviewed. Twelve patients (M:6, F:6, mean age 42.04 $\pm$ 12.43months, mean body weight 13.80$\pm$ 1.94kg) underwent extracardiac conduit Fontan operation with expanded PTFE graft. Mean cardiopulmonary bypass time was 109.7$\pm$26.99minute and mean operation time was 455$\pm$89.51minute. Intraoperative fenestration was performed in 10 patients. The aortic cross clamping was not performed in all patients. Result: There was no early deaths and no postoperative dysrhythmia. Postoperative protein losing enteropathy and prolonged pleural effusion occurred in 1(8.3%) and 4 patients(33.3%). Conduit patency was evaluated by magnetic resonance imaging studies. A 9.84$\pm$3.84% mean reduction in conduit internal diameter and there was no statistical correlation between the change of internal diameter of conduit and the postoperative duration after partial correlation analysis(r=0.019, p=0.955). Conclusion: These results demonstrate that the extracardiac conduit Fontan operation provies good early and midterm results and may reduce the prevalence of late arrhythmia. And there is no correlation between the change of internal diameter of conduit and the postoperative duration after extracardiac conduit Fontan operation with the expanded PTFE graft conduit.

• Journal of the Korea institute for structural maintenance and inspection
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• v.15 no.3
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• pp.142-154
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• 2011

This study predicted the probability of corrosion initiation of reinforced concrete tunnel boxes structures using the Monte Carlo Simulation. For the inner wall and outer wall in the tunnel boxes, exposed to airborne chloride ion and seawater directly respectively, statistical values of parameters like diffusion coefficient D, surface chloride content $C_s$, cover depth c, and the chloride threshold level $C_{lim}$ were examined from experiment or literature review. Their average values accounted for $3.77{\times}10^{-12}m^2/s$, 3.0% by weight of cement, 94.7mm and 45.5mm for outer wall and inner wall, respectively, and 0.69% by weight of cement for D, $C_s$, c, and $C_{lim}$, respectively. With these parametric values, the distribution of chloride contents at rebar with time and the probability of corrosion initiation of the tunnel boxes, inner wall and outer wall, was examined by considering time dependency of chloride transport. From the examination, the histogram of chloride contents at rebar is closer to a gamma distribution, and the mean value increases with time, while the coefficient of variance decreases with time. It was found that the probability of corrosion initiation and the time to corrosion were dependent on the time dependency of chloride transport. Time independent model predicted time to corrosion initiation of inner wall and outer wall as 8 and 12 years, respectively, while 178 and 283 years of time to corrosion was calculated by time dependent model for inner wall and outer wall, respectively. For time independent model, the probability of corrosion at 100 years of exposure for inner wall and outer wall was ranged 59.5 and 95.5%, respectively, while time dependent model indicated 2.9 and 0.2% of the probability corrosion, respectively. Finally, impact of $C_{lim}$, including values specified in current codes, on the probability of corrosion initiation and corrosion free life is discussed.