• Journal of Chest Surgery
• /
• v.30 no.6
• /
• pp.566-572
• /
• 1997

A major obstacles to evaluation of newly-developed treatment strategy for human lung cancer has been the lack of appropriate experimental animal models. We describe a new experimental model of orthotopically-developed non-small cell lung cancer in nude rat, involving inoculation of tumor cell suspension by thoracotomy. Over 40 direct implantation to the periphery of the lung has been performed to date, each requiring less than'1 hour for completion. This model has been used to perform a series of experiments to investigate whether the rat lung and surrounding structures trapped tumor cells with 2 different non-small cell lung cancer cell lines(NCI-H46O and NCI-H1299). Every animal showed development of tumor masses, which were loculated at the periphery of the lung karenchyma and identified also by radiography. After 3 weetu of the inoculation, tumor develop meat at the mediastinal strutures were identified. The life expectancies of the victims were different between the cell lines, but were approximately 5 weeks when NCI-H46O cell line was used. This new orthotopic lung cancer model may be facilitate future studies of the new therapeutics of localized non-small cell lung cancer .

• Journal of Bio-Environment Control
• /
• v.31 no.3
• /
• pp.152-162
• /
• 2022

This study developed simulation model for predicting the greenhouse interior environment using artificial intelligence machine learning techniques. Various methods have been studied to predict the internal environment of the greenhouse system. But the traditional simulation analysis method has a problem of low precision due to extraneous variables. In order to solve this problem, we developed a model for predicting the temperature inside the greenhouse using machine learning. Machine learning models are developed through data collection, characteristic analysis, and learning, and the accuracy of the model varies greatly depending on parameters and learning methods. Therefore, an optimal model derivation method according to data characteristics is required. As a result of the model development, the model accuracy increased as the parameters of the hidden unit increased. Optimal model was derived from the GRU algorithm and hidden unit 6 (r² = 0.9848 and RMSE = 0.5857℃). Through this study, it was confirmed that it is possible to develop a predictive model for the temperature inside the greenhouse using data outside the greenhouse. In addition, it was confirmed that application and comparative analysis were necessary for various greenhouse data. It is necessary that research for development environmental control system by improving the developed model to the forecasting stage.

• Proceedings of the Korea Water Resources Association Conference
• /
• 2007.05a
• /
• pp.522-526
• /
• 2007

항공사진을 이용하여 하천의 경년변화를 조사하다 보면, 사주 변동에 따라 하천의 주 흐름이 다양하게 변화되고 있음을 알 수 있다. 이처럼 특정 하천의 지정된 구간에서의 흐름변동은 많은 시간에 걸쳐 이루어진다. 바꾸어 말하면, 짧은 시간 동안 자연하천에서의 주 흐름 변화를 관찰 하기는 일반적으로 매우 어렵다. 본 연구에서는 이틀이라는 짧은 시간 동안에, 하천에서의 주 흐름 변동에 따른 특성변화를 조사하였다. 이러한 조사는 "조정지 댐에서의 수문 조작"이라는 인위적인 방법을 동원함으로서 가능하였다. 모든 조정지 댐에서는 하천 유지를 위한 일정양의 물을 수문을 통하여 방류한다. 대청댐 하류에 있는 조정지 댐에는 폭이 약 10m에 이르는 10개의 수문이 있다. 평상시에는 우안으로부터 5번째에 있는 중앙의 수문을 개방하여 초당 약 18톤의 물을 방류한다. 그러므로 본 연구에서는 방류하고자 하는 지점의 수문높이를 조정하여 일정량을 유지한 채, 수문의 위치를 중앙에서 좌안 그리고 우안의 순으로 변경 하였다. 방류 수문 위치를 변경함에 따라 하천에서의 수리특성을 조사하기 위하여, 흐름이 안정 될 때까지 충분히 기다린 후, 각각의 경우에서의 하류지역을 대상으로 현지관측 및 수치실험을 실시하였다. 조사는, 첫째 지형측량, 유량측정 및 수위변동 등을 포함한 정밀현장조사, 둘째 일반적인 모델에 정밀조사 결과를 적용시킴으로서 얻을 수 있는 가시화 기법 개발 등의 순으로 진행하였다. 수치실험에 사용한 모델은 하천에서의 흐름거동을 2차원적으로 해석하는데 많이 사용되고 있는 상용프로그램인 SMS (Surface-Water Modeling System)의 RMA2 모형이다. 이모형은 RMA (Resource Management Associates, Inc.)에 의해 처음 개발된 2차원 유한요소 모델이며 지배방정식은 z방향을 수심 적분한 2차원 천수방정식으로, x와 y방향에 대한 Navier-Stokes 방정식과 연속 방정식으로 구성된다. 본 연구에서는 현장 조사 시 지배인자 파악의 중요성 및 수치계산을 위한 검증자료의 필요성을 강조하기 위하여, 일반적인 방법으로 수행한 계산 결과 및 다양한 현장 특성을 고려한 계산 결과를 비교 하였다. 그 결과 본 연구는 (1)최신 장비들의 도입 및 검증과 기존 장비의 활용 범위 확대, (2)기존의 상용 프로그램을 이용한 하천 흐름특성의 가시화 실현 등에 의의가 있다고 사료된다.

• The Journal of the Acoustical Society of Korea
• /
• v.33 no.3
• /
• pp.174-183
• /
• 2014

When a active sonar signal is transmitted and returned back from a target, it has been distorted by various properties of acoustic channel such as multipath arrivals. And signals have been appeared to be different form by target position and attitude. Therefore, we simulated the target echo signal using 3 dimensional target model include reflects target features. In this paper, we develop components form of a simulated target model is made up equally spaced highlight points, and each part of the target consists of shape function. We can simulate a target echo signal and Target strength (TS) according to wave incident angle. To verify, we made small scale target in kit form and we had got underwater target signal for comparing simulation result in water tank.

• Journal of the Korean Society of Propulsion Engineers
• /
• v.17 no.2
• /
• pp.128-134
• /
• 2013

A 2-way solenoid valve regulates to maintain the pressure of ullage volume of propellant tanks when the command is given by control system for the liquid-propellant feeding system of space launch vehicle. The simulation model of solenoid valve for pressurization is designed with AMESim to verify the designs and evaluate the dynamic characteristics and pneumatic behaviors of valve. To improve the accuracy of the model, numerical flow analysis by using FLUNET code. The simulation results of their operating durations of valve by AMESim analysis are matched up with the results of experiments and validate valve model. Using the model, we analyze performance of valve; opening/closing pressure, operating time on various design factors of basic valve and control valve; geometrical size of valve seat, ratio of basic valve and sealing area.

• Asia-Pacific Journal of Business Venturing and Entrepreneurship
• /
• v.18 no.2
• /
• pp.53-66
• /
• 2023

Role models are also known to influence an individual's job or career choice. The positive effect of role models on entrepreneurship has already been revealed through many precious researches. It is said that people choose not only family members who are related by blood, such as parents, siblings, and relatives, but also acquaintances whom they have met through social relationships as role models. In this study, we divided into entrepreneurs with no role models other than themselves and entrepreneurs with role models. In addition, we classified parental siblings and relative role models as role models with strong ties, and acquaintance role models as role models with weak ties. We analyzed the differences in personal attributes, entrepreneurial orientation factors, and learning orientation between the entrepreneurs with role models and those without role models. Also, the differences in personal attributes, innovativeness, proactiveness, risk-taking propensity, and learning orientation between the entrepreneurs with strong ties role models and those with weak ties role models were examined. The empirical analysis results are as follows. First, it was found that the proportion of women entrepreneurs without role models is higher. Second, the entrepreneurs with role models with weak ties tend to run larger scale start-ups. Third, it was found that the entrepreneurs with role models of weak ties tend to have higher learning orientation. Fourth, gender shows the greatest influence on th absence or presence of role models. Fifth, it was found that learning orientation and startup size have the greatest influence on the decision of the role model with weak ties or that with strong ties.

• 한국HCI학회:학술대회논문집
• /
• 2007.02a
• /
• pp.681-687
• /
• 2007

첨단 기술의 발전과 함께 장애인 및 노약자의 삶의 질에 대한 관심이 증가함에 따라 사용자가 각종 시스템들을 보다 쉽게 제어할 수 있는 방법들이 많이 연구되고 있다. 그 중 하나로 정의된 손 움직임 동작을 인식하여 가전기기 혹은 환경 제어 시스템, 홈 로봇 등에 명령을 내리는 기술을 예로 들 수 있다. 하지만, 정의된 손 움직임이 일상생활에서 발생하는 동작과 비슷한 경우 오작동을 일으킬 가능성이 있으며, 이를 차단하기 위해 복잡한 동작을 명령어로 사용할 경우 사용자의 편의성을 떨어뜨린다. 본 논문에서는 이러한 문제를 해결하기 위해 비슷한 동작 중에서 특정 동작을 검출할 수 있는 퍼지 가비지 모델을 제안한다. 퍼지 가비지 모델이란 인식하고자 하는 특정 동작을 제외한 다른 유사 동작의 특성을 반영하여 구현한 퍼지 모델을 말한다. 따라서 사용자의 동작으로부터 특징 값을 구한 후 이를 특정 동작에 대한 퍼지 모델과 퍼지 가비지 모델에 각각 대입하여 얻은 결과를 비교해서 어떤 동작이 발생하였는지 결정한다. 또한 사용자의 행동 특성은 개인마다 다르게 나타나고 동일 사용자라 하더라도 경우에 따라 동작에 편차가 나타날 수 있기 때문에 특정 사용자에 대한 시스템의 적응이 필요하다. 이를 위해 다양한 경우를 고려하여 최적화된 값을 찾을 수 있는 진화 알고리즘을 이용하여 퍼지 모델 파라미터를 갱신하는 방법을 제안한다. 제안한 방법의 타당성을 검증하기 위해 5명의 사용자로부터 명령 동작과 의미 없는 유사 동작의 데이터를 획득하여 실험 결과를 보인다.

• Transactions of the Korean Society of Mechanical Engineers A
• /
• v.41 no.7
• /
• pp.585-590
• /
• 2017

Vehicle behavior is determined by forces and a torques generated at the ground contact surface of the tire. Various tire models are used to calculate the forces and torques acting on the tire. The brush model calculates the forces and torques with fewer coefficients than other tire models. However, owing to fewer degrees of freedom in calculating the forces, this model has limitations in precisely expressing measured data. In this study, this problem was addressed by adding the least parameters to the friction coefficient and tire properties of the brush model, and the proposed model was validated.

• Journal of the Computational Structural Engineering Institute of Korea
• /
• v.17 no.4
• /
• pp.389-403
• /
• 2004

This study presents the structural model modification based on the modal data such as natural frequencies and mode shapes. Preliminary structural model can be obtained using design drawings and field measurement, and therefore the deteriorated stiffness of a structure and the effect of the boundary conditions are difficult to be evaluated in preliminary analysis model, and the preliminary model can be modified using structural response data including static and/or dynamic characteristics. In this study, the structural model is modified based on the structural modal data using genetic algorithm. Modal testing were carried out for Imjin River Bridge and Hangjoo Bridge, the modal properties were estimated using modal identification techniques, and finally the structural models were updated using genetic algorithm. The modified structural model could give us more reliable structural analysis results and therefore those can be used for structural performance evaluation such as load carrying capacity and seismic capacity.

• Journal of Korean Society of Coastal and Ocean Engineers
• /
• v.31 no.6
• /
• pp.458-467
• /
• 2019

The purpose of this study is the suggestion of optimized parameters in OI (Optimal Interpolation) by experimental study. The observation of applying optimal interpolation is ADCP (Acoustic Doppler Current Profiler) data at the southwestern sea of Korea. FVCOM (Finite Volume Coastal Ocean Model) is used for the barotropic model. OI is to the estimation of the gain matrix by a minimum value between the background error covariance and the observation error covariance using the least square method. The scaling factor and correlation radius are very important parameters for OI. It is used to calculate the weight between observation data and model data in the model domain. The optimized parameters from the experiments were found by the Taylor diagram. Constantly each observation point requires optimizing each parameter for the best assimilation. Also, a high accuracy of numerical model means background error covariance is low and then it can decrease all of the parameters in OI. In conclusion, it is expected to have prepared the foundation for research for the selection of ocean observation points and the construction of ocean prediction systems in the future.